IL94885A - Muramyl dipeptide derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

Muramyl dipeptide derivatives, their preparation and pharmaceutical compositions containing them Download PDF

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Publication number
IL94885A
IL94885A IL9488590A IL9488590A IL94885A IL 94885 A IL94885 A IL 94885A IL 9488590 A IL9488590 A IL 9488590A IL 9488590 A IL9488590 A IL 9488590A IL 94885 A IL94885 A IL 94885A
Authority
IL
Israel
Prior art keywords
compound according
compound
cells
substance
treatment
Prior art date
Application number
IL9488590A
Other languages
English (en)
Other versions
IL94885A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL94885A0 publication Critical patent/IL94885A0/xx
Publication of IL94885A publication Critical patent/IL94885A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL9488590A 1989-06-29 1990-06-27 Muramyl dipeptide derivatives, their preparation and pharmaceutical compositions containing them IL94885A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3921246 1989-06-29
DE3921248 1989-06-29
DE3924874 1989-07-27
DE3924875 1989-07-27

Publications (2)

Publication Number Publication Date
IL94885A0 IL94885A0 (en) 1991-04-15
IL94885A true IL94885A (en) 1994-07-31

Family

ID=27434666

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9488590A IL94885A (en) 1989-06-29 1990-06-27 Muramyl dipeptide derivatives, their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US5210072A (de)
EP (1) EP0406175B1 (de)
JP (1) JPH0737479B2 (de)
KR (1) KR910000775A (de)
AT (1) ATE130313T1 (de)
AU (1) AU636150B2 (de)
CA (1) CA2019922A1 (de)
DE (1) DE69023559T2 (de)
ES (1) ES2079464T3 (de)
FI (1) FI903232A7 (de)
HU (1) HU205147B (de)
IE (1) IE902345A1 (de)
IL (1) IL94885A (de)
MY (1) MY105727A (de)
NZ (1) NZ234270A (de)
PL (1) PL163888B1 (de)
PT (1) PT94517A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ240369A (en) * 1990-10-30 1993-09-27 Daiichi Seiyaku Co Muramyl dipeptide derivatives and vaccine compositions
US5919466A (en) * 1993-10-01 1999-07-06 Gerbu Biotechnik Gmbh Method for improving the yield of immunoantibodies in the vaccination of animals and humans
GB9320820D0 (en) * 1993-10-08 1993-12-01 Biokine Tech Ltd Compounds for medicinal use
GB9326518D0 (en) * 1993-12-29 1994-03-02 Sandoz Ltd Organic compounds
GB9413935D0 (en) * 1994-07-11 1994-08-31 Peptech Uk Ltd Use of maramyl peptide compounds
US6270758B1 (en) 1998-10-08 2001-08-07 Duke University Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects
US10927147B2 (en) 2015-12-10 2021-02-23 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
US12134664B2 (en) 2015-12-10 2024-11-05 Bharat Biotech International Ltd. Muramyl peptide derivatives
CN108883080B (zh) 2015-12-15 2021-12-21 巴拉特生物技术国际有限公司 胞壁酰肽衍生物化合物、其合成及其用途
US10717703B2 (en) 2017-08-21 2020-07-21 Celgene Corporation Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897308A (en) * 1975-06-30 1990-01-30 L'oreal Compositions comprising aqueous dispersions of lipid spheres
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
US4315913A (en) * 1980-06-09 1982-02-16 Merck & Co. Inc. Immunologically active dipeptidyl 2-amino-1,2-dideoxy-D-glucose derivatives and methods of preparation
IL64397A0 (en) * 1981-01-07 1982-02-28 Weder Hans G Process for the preparation of liposomal medicaments
JPS58172399A (ja) * 1982-04-05 1983-10-11 Dai Ichi Seiyaku Co Ltd ムラミルトリペプチド誘導体
JPS6078997A (ja) * 1983-10-07 1985-05-04 Dai Ichi Seiyaku Co Ltd ムラミルペプチド誘導体
FR2564096B1 (fr) * 1984-05-11 1988-02-19 Anvar Derives lipophiles de muramylpeptides ayant des proprietes d'activation des macrophages, compositions les contenant et procede pour les obtenir

Also Published As

Publication number Publication date
IE902345A1 (en) 1991-01-16
JPH03135998A (ja) 1991-06-10
EP0406175A2 (de) 1991-01-02
DE69023559D1 (de) 1995-12-21
ATE130313T1 (de) 1995-12-15
PT94517A (pt) 1991-02-08
NZ234270A (en) 1993-02-25
ES2079464T3 (es) 1996-01-16
PL163888B1 (pl) 1994-05-31
HU903880D0 (en) 1990-11-28
AU5787590A (en) 1991-01-03
HUT54180A (en) 1991-01-28
EP0406175A3 (en) 1992-04-01
KR910000775A (ko) 1991-01-30
EP0406175B1 (de) 1995-11-15
FI903232A0 (fi) 1990-06-27
JPH0737479B2 (ja) 1995-04-26
DE69023559T2 (de) 1996-06-27
AU636150B2 (en) 1993-04-22
CA2019922A1 (en) 1990-12-29
IL94885A0 (en) 1991-04-15
IE902345L (en) 1990-12-29
MY105727A (en) 1994-11-30
US5210072A (en) 1993-05-11
FI903232A7 (fi) 1990-12-30
PL285842A1 (en) 1991-03-11
HU205147B (en) 1992-03-30

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