IL96081A - Benzocycloalkyl pyridinamines, a process and intermediates for their preparation and their use as medicaments - Google Patents

Benzocycloalkyl pyridinamines, a process and intermediates for their preparation and their use as medicaments

Info

Publication number
IL96081A
IL96081A IL9608190A IL9608190A IL96081A IL 96081 A IL96081 A IL 96081A IL 9608190 A IL9608190 A IL 9608190A IL 9608190 A IL9608190 A IL 9608190A IL 96081 A IL96081 A IL 96081A
Authority
IL
Israel
Prior art keywords
compound
formula
pyridinyl
amino
indole
Prior art date
Application number
IL9608190A
Other languages
English (en)
Other versions
IL96081A0 (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL96081A0 publication Critical patent/IL96081A0/xx
Publication of IL96081A publication Critical patent/IL96081A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
IL9608190A 1989-10-24 1990-10-22 Benzocycloalkyl pyridinamines, a process and intermediates for their preparation and their use as medicaments IL96081A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/425,712 US4992448A (en) 1989-10-24 1989-10-24 Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders

Publications (2)

Publication Number Publication Date
IL96081A0 IL96081A0 (en) 1991-07-18
IL96081A true IL96081A (en) 1994-12-29

Family

ID=23687722

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9608190A IL96081A (en) 1989-10-24 1990-10-22 Benzocycloalkyl pyridinamines, a process and intermediates for their preparation and their use as medicaments

Country Status (17)

Country Link
US (1) US4992448A (de)
EP (1) EP0428878B1 (de)
JP (1) JPH0725748B2 (de)
KR (1) KR0169109B1 (de)
AT (1) ATE123492T1 (de)
AU (1) AU626470B2 (de)
CA (1) CA2028287C (de)
DE (1) DE69019920T2 (de)
DK (1) DK0428878T3 (de)
ES (1) ES2074508T3 (de)
FI (1) FI905191A7 (de)
IE (1) IE903810A1 (de)
IL (1) IL96081A (de)
NO (1) NO904575L (de)
PH (1) PH27409A (de)
PT (1) PT95651B (de)
ZA (1) ZA908460B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008818D0 (en) * 1990-04-19 1990-06-13 Ici Plc Amine derivatives
US5102891A (en) * 1990-07-23 1992-04-07 Hoechst-Roussel Pharmaceuticals Inc. 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates
DE69531458T2 (de) * 1994-05-27 2004-08-05 Glaxosmithkline S.P.A. Chinolinderivate als tachykinin nk3 rezeptor antagonisten
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
US6339093B1 (en) * 1999-10-08 2002-01-15 Hoffmann-La Roche Inc. Isoquinoline derivatives
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2671508B1 (de) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-Informatiksystem
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質(rap)結合体の投与による肝障害の処置
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3118884A (en) * 1959-10-19 1964-01-21 Schering Corp Derivatives of 3-azaphenothiazine and 3-azaphenoxazine
CH498114A (de) * 1967-06-02 1970-10-31 Ruetgerswerke Ag Verfahren zur Herstellung von 2-N-substituierten 2-Amino-5-nitropyridinen
US3495969A (en) * 1967-09-25 1970-02-17 Mobil Oil Corp Substituted nitropyridines as herbicides
US3576616A (en) * 1969-05-15 1971-04-27 Monsanto Co Herbicidal compositions and methods
US3721676A (en) * 1969-11-12 1973-03-20 Merck & Co Inc Certain 3-amino-2(1h)pyridones
US4042697A (en) * 1972-10-19 1977-08-16 Allen & Hanburys Limited Isoquinolium compounds for treating diabetes
US4190660A (en) * 1978-08-11 1980-02-26 Siu Patrick M Anti-drug withdrawal syndrome composition and method of use
GB2073736B (en) * 1979-10-03 1984-02-01 Ici Ltd Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
NO904575L (no) 1991-04-25
EP0428878A2 (de) 1991-05-29
PT95651B (pt) 1997-12-31
DE69019920D1 (de) 1995-07-13
US4992448A (en) 1991-02-12
JPH03151378A (ja) 1991-06-27
ATE123492T1 (de) 1995-06-15
AU626470B2 (en) 1992-07-30
DK0428878T3 (da) 1995-10-16
FI905191A0 (fi) 1990-10-22
EP0428878A3 (en) 1991-09-25
EP0428878B1 (de) 1995-06-07
FI905191A7 (fi) 1991-04-25
CA2028287C (en) 2001-04-03
KR0169109B1 (ko) 1999-01-15
IL96081A0 (en) 1991-07-18
PT95651A (pt) 1991-09-13
AU6485890A (en) 1991-05-02
CA2028287A1 (en) 1991-04-25
KR910007911A (ko) 1991-05-30
NO904575D0 (no) 1990-10-23
JPH0725748B2 (ja) 1995-03-22
ZA908460B (en) 1991-08-28
DE69019920T2 (de) 1995-11-16
IE903810A1 (en) 1991-04-24
ES2074508T3 (es) 1995-09-16
PH27409A (en) 1993-06-21

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Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)
RH Patent void