IL96734A - Spray pharmaceuticals containing autoantigens - Google Patents

Spray pharmaceuticals containing autoantigens

Info

Publication number: IL96734A
Authority: IL; Israel
Prior art keywords: mbp; aerosol; disease; autoimmune; administration
Prior art date: 1989-12-20

Application number

IL9673490A

Other languages

English (en)

Hebrew (he)

Other versions

IL96734A0 (en

Original Assignee

Brigham & Womens Hospital

Autoimmune Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-20

Filing date

1990-12-20

Publication date

1996-11-14

1990-12-20 Application filed by Brigham & Womens Hospital, Autoimmune Inc filed Critical Brigham & Womens Hospital

1991-09-16 Publication of IL96734A0 publication Critical patent/IL96734A0/xx

1996-11-14 Publication of IL96734A publication Critical patent/IL96734A/en

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
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IL9673490A 1989-12-20 1990-12-20 Spray pharmaceuticals containing autoantigens IL96734A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US45480689A	1989-12-20	1989-12-20

Publications (2)

Publication Number	Publication Date
IL96734A0 IL96734A0 (en)	1991-09-16
IL96734A true IL96734A (en)	1996-11-14

Family

ID=23806184

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL9673490A IL96734A (en)	1989-12-20	1990-12-20	Spray pharmaceuticals containing autoantigens

Country Status (14)

Country	Link
EP (1)	EP0506785B1 (fr)
JP (1)	JP2625253B2 (fr)
KR (1)	KR0185747B1 (fr)
AT (1)	ATE190496T1 (fr)
AU (1)	AU642693B2 (fr)
BR (1)	BR9007950A (fr)
CA (1)	CA2070281C (fr)
DE (1)	DE69033487T2 (fr)
DK (1)	DK0506785T3 (fr)
ES (1)	ES2144398T3 (fr)
GR (1)	GR3033634T3 (fr)
HU (2)	HUT61487A (fr)
IL (1)	IL96734A (fr)
WO (1)	WO1991008760A1 (fr)

Families Citing this family (50)

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US5869054A (en) *	1987-06-24	1999-02-09	Autoimmune Inc.	Treatment of multiple sclerosis by oral administration of autoantigens
US5849298A (en) *	1987-06-24	1998-12-15	Autoimmune Inc.	Treatment of multiple sclerosis by oral administration of bovine myelin
US5843445A (en) *	1987-06-24	1998-12-01	Autoimmune, Inc.	Method of treating rheumatoid arthritis with type II collagen
US6645504B1 (en)	1987-06-24	2003-11-11	Autoimmune Inc.	Bystander suppression of type I diabetes by oral administration of glucagon
DK0482089T3 (da) *	1989-07-14	1998-05-25	Autoimmune Inc	Fremgangsmåder til behandling af autoimmun uveoretnitis i mennesker
IL99699A (en)	1990-10-10	2002-04-21	Autoimmune Inc	Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
HUT69942A (en) *	1990-10-15	1995-09-28	Brigham & Womens Hospital	Treatment of autoimmun diseases by oral administration of autoantigenes
HU220357B (hu) *	1992-02-28	2001-12-28	Autoimmune Inc.	Eljárás és készítmények autoimmun betegségek kezelésére bystander antigén alkalmazásával
EP0662838A4 (fr) *	1992-09-25	1996-07-24	Autoimmune Inc	Procede de traitement de la polyarthrite rhumatoide avec du collagene de type ii.
EP0705108A4 (fr) *	1993-06-02	1997-08-06	Tvw Telethon Inst Child Health	Peptides caches permettant d'induire une tolerance immunologique
IL115766A0 (en) *	1994-10-25	1996-01-19	Immulogic Pharma Corp	Composition and treatment for multiple sclerosis
US6488933B2 (en)	1995-07-05	2002-12-03	Yeda Research And Development Co. Ltd.	Preparations for the treatment of T cell mediated diseases
US5856446A (en) *	1995-07-07	1999-01-05	Autoimmune Inc.	Method of treating rheumatoid arthritis with low dose type II collagen
JP3935938B2 (ja) *	1996-01-05	2007-06-27	オートイミューンインク	▲ｉｉ▼型コラーゲンの調製法
AUPO269996A0 (en) *	1996-10-01	1996-10-24	Walter And Eliza Hall Institute Of Medical Research, The	A method of prophylaxis and treatment
AU741439B2 (en)	1996-12-30	2001-11-29	Battelle Memorial Institute	Formulation and method for treating neoplasms by inhalation
US7097845B2 (en)	1997-04-23	2006-08-29	Jacob Sten Petersen	Combinations of antigen and mucosal binding component for inducing specific immunological tolerance
US7588766B1 (en)	2000-05-26	2009-09-15	Elan Pharma International Limited	Treatment of amyloidogenic disease
US7179892B2 (en)	2000-12-06	2007-02-20	Neuralab Limited	Humanized antibodies that recognize beta amyloid peptide
US6923964B1 (en)	1997-12-02	2005-08-02	Neuralab Limited	Active immunization of AScr for prion disorders
US7790856B2 (en)	1998-04-07	2010-09-07	Janssen Alzheimer Immunotherapy	Humanized antibodies that recognize beta amyloid peptide
US6750324B1 (en)	1997-12-02	2004-06-15	Neuralab Limited	Humanized and chimeric N-terminal amyloid beta-antibodies
US6787523B1 (en)	1997-12-02	2004-09-07	Neuralab Limited	Prevention and treatment of amyloidogenic disease
US6913745B1 (en)	1997-12-02	2005-07-05	Neuralab Limited	Passive immunization of Alzheimer's disease
US6905686B1 (en)	1997-12-02	2005-06-14	Neuralab Limited	Active immunization for treatment of alzheimer's disease
TWI239847B (en)	1997-12-02	2005-09-21	Elan Pharm Inc	N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US20080050367A1 (en)	1998-04-07	2008-02-28	Guriq Basi	Humanized antibodies that recognize beta amyloid peptide
US6761888B1 (en)	2000-05-26	2004-07-13	Neuralab Limited	Passive immunization treatment of Alzheimer's disease
US6710226B1 (en)	1997-12-02	2004-03-23	Neuralab Limited	Transgenic mouse assay to determine the effect of Aβ antibodies and Aβ Fragments on alzheimer's disease characteristics
US20030147882A1 (en)	1998-05-21	2003-08-07	Alan Solomon	Methods for amyloid removal using anti-amyloid antibodies
US6787637B1 (en)	1999-05-28	2004-09-07	Neuralab Limited	N-Terminal amyloid-β antibodies
UA81216C2 (en)	1999-06-01	2007-12-25		Prevention and treatment of amyloid disease
SE9902155L (sv) *	1999-06-09	2000-12-10	Bjoern Rydevik	Serum antibodies
US7897575B2 (en)	2000-05-24	2011-03-01	The United States Of America As Represented By The Department Of Health And Human Services	Treatment and prevention of vascular dementia
US7261896B2 (en)	2000-05-24	2007-08-28	United States Of America As Represented By The Secretary Of The Department Of Health And Human Services National Institutes Of Health	Methods for preventing strokes by inducing tolerance to e-selectin
PE20020574A1 (es)	2000-12-06	2002-07-02	Wyeth Corp	Anticuerpos humanizados que reconocen el peptido amiloideo beta
US7700751B2 (en)	2000-12-06	2010-04-20	Janssen Alzheimer Immunotherapy	Humanized antibodies that recognize β-amyloid peptide
MY139983A (en)	2002-03-12	2009-11-30	Janssen Alzheimer Immunotherap	Humanized antibodies that recognize beta amyloid peptide
DE10230381A1 (de)	2002-07-05	2004-01-22	Institut für Medizintechnologie Magdeburg GmbH, IMTM	Verwendung von Inhibitoren der Alanyl-Aminopeptidasen und diese umfassende pharmazeutischen Zubereitungen
AU2003266081A1 (en)	2002-09-13	2004-04-30	Universite Laval	Nucleoside triphosphate diphosphohydrolase (ntpdase 8) and uses thereof
TWI306458B (en)	2003-05-30	2009-02-21	Elan Pharma Int Ltd	Humanized antibodies that recognize beta amyloid peptide
EP1838348B1 (fr)	2004-12-15	2013-06-26	Janssen Alzheimer Immunotherapy	Anticorps du peptide beta-amyloide humanises utilises dans l'amelioration de la cognition
US7625560B2 (en)	2004-12-15	2009-12-01	Janssen Alzheimer Immunotherapy	Humanized antibodies that recognize beta amyloid peptide
EP1910410B1 (fr)	2005-07-01	2011-10-26	Forsyth Dental Infirmary for Children	Essais de detection d'antigenes de la tuberculose et vaccins
US8784810B2 (en)	2006-04-18	2014-07-22	Janssen Alzheimer Immunotherapy	Treatment of amyloidogenic diseases
US8003097B2 (en)	2007-04-18	2011-08-23	Janssen Alzheimer Immunotherapy	Treatment of cerebral amyloid angiopathy
DK2182983T3 (da)	2007-07-27	2014-07-14	Janssen Alzheimer Immunotherap	Behandling af amyloidogene sygdomme med humaniserede anti-abeta antistoffer
JO3076B1 (ar)	2007-10-17	2017-03-15	Janssen Alzheimer Immunotherap	نظم العلاج المناعي المعتمد على حالة apoe
US9067981B1 (en)	2008-10-30	2015-06-30	Janssen Sciences Ireland Uc	Hybrid amyloid-beta antibodies
US20130236484A1 (en)	2012-03-08	2013-09-12	Detectogen Inc.	Leishmaniasis antigen detection assays and vaccines

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* Cited by examiner, † Cited by third party
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US379778A (en) *		1888-03-20		Machine for mitering printers rules
US65734A (en) *		1867-06-11		Joseph fantou
EP0359783B2 (fr) *	1987-06-24	2002-04-17	Autoimmune, Inc.	Traitement de maladies auto-immunitaires par administration orale d'auto-antigenes
AU645244B2 (en) *	1988-04-08	1994-01-13	Genetics Institute, Llc	Bone and cartilage inductive compositions

1990
- 1990-12-17 CA CA002070281A patent/CA2070281C/fr not_active Expired - Lifetime
- 1990-12-17 AT AT91901622T patent/ATE190496T1/de not_active IP Right Cessation
- 1990-12-17 AU AU69791/91A patent/AU642693B2/en not_active Expired
- 1990-12-17 DK DK91901622T patent/DK0506785T3/da active
- 1990-12-17 EP EP91901622A patent/EP0506785B1/fr not_active Expired - Lifetime
- 1990-12-17 BR BR909007950A patent/BR9007950A/pt not_active Application Discontinuation
- 1990-12-17 JP JP3501992A patent/JP2625253B2/ja not_active Expired - Fee Related
- 1990-12-17 DE DE69033487T patent/DE69033487T2/de not_active Expired - Lifetime
- 1990-12-17 HU HU922072A patent/HUT61487A/hu unknown
- 1990-12-17 ES ES91901622T patent/ES2144398T3/es not_active Expired - Lifetime
- 1990-12-17 KR KR1019920701486A patent/KR0185747B1/ko not_active Expired - Lifetime
- 1990-12-17 WO PCT/US1990/007455 patent/WO1991008760A1/fr not_active Ceased
- 1990-12-20 IL IL9673490A patent/IL96734A/en not_active IP Right Cessation
1995
- 1995-02-15 HU HU95P/P00074P patent/HU210715A9/hu unknown
2000
- 2000-06-08 GR GR20000401321T patent/GR3033634T3/el unknown

Also Published As

Publication number	Publication date
KR920703081A (ko)	1992-12-17
HUT61487A (en)	1993-01-28
EP0506785A4 (en)	1993-09-08
AU642693B2 (en)	1993-10-28
DE69033487T2 (de)	2000-06-29
GR3033634T3 (en)	2000-10-31
HU9202072D0 (en)	1992-09-28
DK0506785T3 (da)	2000-07-24
BR9007950A (pt)	1992-10-27
WO1991008760A1 (fr)	1991-06-27
CA2070281C (fr)	2005-08-23
JP2625253B2 (ja)	1997-07-02
ES2144398T3 (es)	2000-06-16
EP0506785A1 (fr)	1992-10-07
AU6979191A (en)	1991-07-18
JPH05504341A (ja)	1993-07-08
IL96734A0 (en)	1991-09-16
KR0185747B1 (ko)	1999-05-01
CA2070281A1 (fr)	1991-06-21
ATE190496T1 (de)	2000-04-15
DE69033487D1 (de)	2000-04-20
EP0506785B1 (fr)	2000-03-15
HU210715A9 (en)	1995-06-28

Legal Events

Date	Code	Title
1997-04-15	FF	Patent granted
1997-11-20	KB	Patent renewed
2001-04-30	KB	Patent renewed
2005-02-20	KB	Patent renewed
2009-07-20	KB	Patent renewed
2011-07-31	EXP	Patent expired

Publication	Publication Date	Title
EP0506785B1 (fr)	2000-03-15	Traitement ameliore de maladies auto-immunes par administration par aerosol d'auto-antigenes
US5645820A (en)	1997-07-08	Treatment of autoimmune diseases by aerosol administration of autoantigens
US5571499A (en)	1996-11-05	Treatment of autoimmune diseases by aerosol administration of autoantigens
US5571500A (en)	1996-11-05	Treatment of autoimmune diseases through administration by inhalation of autoantigens
US5641474A (en)	1997-06-24	Prevention of autoimmune diseases by aerosol administration of autoantigens
AU720695B2 (en)	2000-06-08	Bystander suppression of autoimmune diseases
EP1033998B1 (fr)	2005-10-19	Suppression des modifications liees aux beta-amyloides dans la maladie d'alzheimer
US5783188A (en)	1998-07-21	Method of treating rheumatoid arthritis with type collagen peptide fragments containing repeating sequences
US6645504B1 (en)	2003-11-11	Bystander suppression of type I diabetes by oral administration of glucagon
WO1994007520A9 (fr)	1994-07-07	Procede de traitement de la polyarthrite rhumatoide avec du collagene de type ii
WO1994007520A1 (fr)	1994-04-14	Procede de traitement de la polyarthrite rhumatoide avec du collagene de type ii
IL97446A (en)	1996-03-31	Medicinal product for the improvement of down-regulation of autoimmune diseases
US5935577A (en)	1999-08-10	Treatment of autoimmune disease using tolerization in combination with methotrexate
KR20000070460A (ko)	2000-11-25	메토트렉세이트와 공동으로 내성화를 사용한 자기면역질병의 치료
WO1998032451A9 (fr)	1998-12-30	Traitement des maladies auto-immunes a l'aide d'une tolerance induite en combinaison avec du methotrexate
US20010007758A1 (en)	2001-07-12	Treatment of multiple sclerosis using COP-1 and Th2-enhancing cytokines
EP0752880A1 (fr)	1997-01-15	Traitement de maladies auto-immunes utilisant la tolerance orale et/ou l'interferon de type i
CA2410563C (fr)	2013-04-23	Methodes de prevention des accidents vasculaires cerebraux moyennant l'induction d'une tolerance a e-selectin
AU2001264813A1 (en)	2002-02-21	Methods for preventing strokes by inducing tolerance to E-selectin
WO1999037315A1 (fr)	1999-07-29	Derives chimiques d'autoantigenes et de peptides suppresseurs d'auto-immunisation, et preparations pharmaceutiques les contenant
EP1842551A1 (fr)	2007-10-10	E-selectin pour le traitement ou la prevention des accidents vasculaires cerebraux
EP0662838A1 (fr)	1995-07-19	Procede de traitement de la polyarthrite rhumatoide avec du collagene de type ii
US20040115217A1 (en)	2004-06-17	Bystander suppression of autoimmune diseases
AU2005235514A1 (en)	2005-12-08	Pharmaceutical formulations and methods for preventing or treating damage to brain tissue