IL98149A0 - Disulfide derivatives of mercapto-acylamino acids - Google Patents

Disulfide derivatives of mercapto-acylamino acids

Info

Publication number: IL98149A0
Authority: IL; Israel
Prior art keywords: lower alkyl; aryl; heteroaryl; alkyl; mercapto
Prior art date: 1990-05-17

Application number

IL98149A

Other languages

English (en)

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-17

Filing date

1991-05-15

Publication date

1992-06-21

1991-05-15 Application filed by Schering Corp filed Critical Schering Corp

1992-06-21 Publication of IL98149A0 publication Critical patent/IL98149A0/xx

Links

150000002019 disulfides Chemical class 0.000 title abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 10
125000003118 aryl group Chemical group 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 4
125000001072 heteroaryl group Chemical group 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
208000024172 Cardiovascular disease Diseases 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
125000003396 thiol group Chemical class [H]S* 0.000 abstract 2
239000005541 ACE inhibitor Substances 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
125000004659 aryl alkyl thio group Chemical group 0.000 abstract 1
125000002102 aryl alkyloxo group Chemical group 0.000 abstract 1
230000001746 atrial effect Effects 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
239000002833 natriuretic agent Substances 0.000 abstract 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL98149A 1990-05-17 1991-05-15 Disulfide derivatives of mercapto-acylamino acids IL98149A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US52537090A	1990-05-17	1990-05-17

Publications (1)

Publication Number	Publication Date
IL98149A0 true IL98149A0 (en)	1992-06-21

Family

ID=24092967

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL98149A IL98149A0 (en)	1990-05-17	1991-05-15	Disulfide derivatives of mercapto-acylamino acids

Country Status (14)

Country	Link
EP (1)	EP0528997B1 (de)
JP (1)	JPH06102648B2 (de)
AT (1)	ATE117988T1 (de)
AU (1)	AU7957291A (de)
DE (1)	DE69107207T2 (de)
DK (1)	DK0528997T3 (de)
ES (1)	ES2069893T3 (de)
GR (1)	GR3015801T3 (de)
IE (1)	IE911666A1 (de)
IL (1)	IL98149A0 (de)
NZ (1)	NZ238154A (de)
PT (1)	PT97669A (de)
WO (1)	WO1991017980A1 (de)
ZA (1)	ZA913685B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ334898A (en) *	1996-10-23	2000-09-29	Warner Lambert Co	Substituted gamma aminobutyric acids as pharamceutical agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4173704A (en) *	1976-05-10	1979-11-06	E. R. Squibb & Sons, Inc.	Dithio aminoacid derivatives
US4053651A (en) *	1976-05-10	1977-10-11	E. R. Squibb & Sons, Inc.	Compounds and method for alleviating angiotensin related hypertension
CH637374A5 (en) *	1977-12-02	1983-07-29	Squibb & Sons Inc	Substituted amino acids
US4329495A (en) *	1981-05-18	1982-05-11	Pfizer Inc.	Enkephalinase enzyme inhibiting compounds
DE3467754D1 (de) *	1983-10-03	1988-01-07	Squibb & Sons Inc	Enkephalinase inhibitors
JPS60136554A (ja) *	1983-10-03	1985-07-20	イ−・ア−ル・スクイブ・アンド・サンズ・インコ−ポレイテッド	エンケフアリナ−ゼ抑制剤
FR2556721B1 (fr) *	1983-12-14	1986-05-16	Roussel Uclaf	Nouveaux derives de o-mercaptopropanamide d'o amino-acides, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
DE3814374A1 (de) *	1988-04-28	1989-11-09	Joerg Schwarzbich	Kugelraste

1991
- 1991-05-15 PT PT97669A patent/PT97669A/pt not_active Application Discontinuation
- 1991-05-15 DE DE69107207T patent/DE69107207T2/de not_active Expired - Fee Related
- 1991-05-15 EP EP91911546A patent/EP0528997B1/de not_active Expired - Lifetime
- 1991-05-15 IL IL98149A patent/IL98149A0/xx unknown
- 1991-05-15 IE IE166691A patent/IE911666A1/en unknown
- 1991-05-15 ES ES91911546T patent/ES2069893T3/es not_active Expired - Lifetime
- 1991-05-15 DK DK91911546.9T patent/DK0528997T3/da active
- 1991-05-15 ZA ZA913685A patent/ZA913685B/xx unknown
- 1991-05-15 AU AU79572/91A patent/AU7957291A/en not_active Abandoned
- 1991-05-15 NZ NZ238154A patent/NZ238154A/xx unknown
- 1991-05-15 AT AT91911546T patent/ATE117988T1/de active
- 1991-05-15 WO PCT/US1991/003251 patent/WO1991017980A1/en not_active Ceased
- 1991-05-15 JP JP3510190A patent/JPH06102648B2/ja not_active Expired - Lifetime
1995
- 1995-04-17 GR GR950400931T patent/GR3015801T3/el unknown

Also Published As

Publication number	Publication date
EP0528997B1 (de)	1995-02-01
NZ238154A (en)	1993-07-27
AU7957291A (en)	1991-12-10
JPH05502038A (ja)	1993-04-15
JPH06102648B2 (ja)	1994-12-14
WO1991017980A1 (en)	1991-11-28
EP0528997A1 (de)	1993-03-03
DE69107207D1 (de)	1995-03-16
GR3015801T3 (en)	1995-07-31
ES2069893T3 (es)	1995-05-16
ATE117988T1 (de)	1995-02-15
DK0528997T3 (da)	1995-04-24
PT97669A (pt)	1992-02-28
IE911666A1 (en)	1991-11-20
ZA913685B (en)	1992-02-26
DE69107207T2 (de)	1995-06-29

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ZA88266B (en)	1988-11-30	Novel treatment
ES8606341A1 (es)	1986-04-16	Un procedimiento para la preparacion de pirazolo piridinas.
EP0320118A3 (en)	1990-07-04	Peptides with collagenase inhibiting activity
MY132145A (en)	2007-09-28	2-amino-1, 3,5-triazines, processes for their preparation, and their use as herbicides and plant growth regulators
DE59000151D1 (de)	1992-07-16	Verfahren zur bekaempfung von pilzen ausserhalb des menschlichen oder tierischen koerpers.
ZA853719B (en)	1986-01-29	New beta-carboline-3-oxadiazolyl derivatives,method of preparing the same and their use
ES2052714T3 (es)	1994-07-16	Un proceso para la preparacion de un compuesto denominado "cornexistina".
TW366263B (en)	1999-08-11	2,4-diamino-1,3,5-triazines, their preparation, and their use as herbicides and plant growth regulators
YU248589A (en)	1992-02-20	Process for obtaining new hypoglichemical agents
AU7077487A (en)	1987-10-22	Sulphide derivatives of acrylic acid
EP0249938A3 (en)	1989-09-06	Imidazolesulfonamide derivatives,herbicides and a method for inhibiting growth of undesirable plants
ZA9110014B (en)	1992-08-26	N-(mercaptoalkyl)amides
AU8445591A (en)	1992-03-17	N-(mercaptoalkyl)ureas and carbamates
GR3015801T3 (en)	1995-07-31	Disulfide derivatives of mercaptoacylamino acids.
OA09644A (en)	1993-04-30	Mercapto-acylamino acids
IL88536A (en)	1993-02-21	Process for the preparation of herbicidal o-carboxylaryl- imidazolinones, and novel intermediates thereof
HU913685D0 (en)	1992-07-28	Method for producing 2-(substituted pyrrholydinyl-thio)-carbapenem derivatives
HU902029D0 (en)	1990-07-28	Process for producing thio-formamide derivatives and pharmaceutical preparatives containing these compounds