IL98231A - Pyrido (3,4-b) pyrrolo (1,2-e) (1,4,5) oxadiazepines and related analogs, a process for their preparation and their use as medicaments - Google Patents

Pyrido (3,4-b) pyrrolo (1,2-e) (1,4,5) oxadiazepines and related analogs, a process for their preparation and their use as medicaments

Info

Publication number
IL98231A
IL98231A IL9823191A IL9823191A IL98231A IL 98231 A IL98231 A IL 98231A IL 9823191 A IL9823191 A IL 9823191A IL 9823191 A IL9823191 A IL 9823191A IL 98231 A IL98231 A IL 98231A
Authority
IL
Israel
Prior art keywords
compound
loweralkyl
hydrogen
methyl
pyrido
Prior art date
Application number
IL9823191A
Other languages
English (en)
Other versions
IL98231A0 (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL98231A0 publication Critical patent/IL98231A0/xx
Publication of IL98231A publication Critical patent/IL98231A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL9823191A 1990-05-25 1991-05-23 Pyrido (3,4-b) pyrrolo (1,2-e) (1,4,5) oxadiazepines and related analogs, a process for their preparation and their use as medicaments IL98231A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/529,082 US5015637A (en) 1990-05-25 1990-05-25 Pyrido[3,4-b]pyrrolo[1,2-e][1,4,5]oxadiazepines

Publications (2)

Publication Number Publication Date
IL98231A0 IL98231A0 (en) 1992-06-21
IL98231A true IL98231A (en) 1994-11-28

Family

ID=24108456

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9823191A IL98231A (en) 1990-05-25 1991-05-23 Pyrido (3,4-b) pyrrolo (1,2-e) (1,4,5) oxadiazepines and related analogs, a process for their preparation and their use as medicaments

Country Status (22)

Country Link
US (1) US5015637A (cs)
EP (1) EP0458331B1 (cs)
JP (1) JP3090500B2 (cs)
KR (1) KR100286405B1 (cs)
AT (1) ATE183746T1 (cs)
AU (1) AU638572B2 (cs)
CA (1) CA2043229C (cs)
CS (1) CS157191A3 (cs)
DE (1) DE69131546T2 (cs)
DK (1) DK0458331T3 (cs)
ES (1) ES2135383T3 (cs)
FI (1) FI912499L (cs)
GR (1) GR3031538T3 (cs)
HU (1) HU207520B (cs)
IE (1) IE911788A1 (cs)
IL (1) IL98231A (cs)
MX (1) MX25922A (cs)
NO (1) NO911998L (cs)
NZ (1) NZ238238A (cs)
PL (1) PL290405A1 (cs)
PT (1) PT97762B (cs)
ZA (1) ZA913951B (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2333691T3 (es) * 1993-05-27 2010-02-26 Board Of Regents Of The University Of Washington Union a gmp ciclica, materiales de fosfodiesterasa especificos a gmp ciclicos y metodos.
AR037853A1 (es) * 2001-12-18 2004-12-09 Syngenta Participations Ag Proceso para la preparacion de derivados de [1,4,5]-oxadiazepinas, y empleo de esos derivados en la preparacion de un herbicida del tipo de la tetrahidropirazolodiona
KR20130072194A (ko) 2010-04-18 2013-07-01 유창준 위치조절이 가능한 삽입물을 갖는 베개

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029672A (en) * 1976-02-26 1977-06-14 American Hoechst Corporation Aminoalkylpyrrolobenzoxazalkanes
US4045448A (en) * 1976-02-26 1977-08-30 American Hoechst Corporation Pyrrolo[2,1-c][1,4]benzoxazepine and benzoxazocine derivatives
FI803908L (fi) * 1979-12-21 1981-06-22 Sandoz Ag Nya pyrrolobenszotriazepiner deras framstaellning och dessa innehaollande farmaceutiska foereningar
US4608374A (en) * 1983-11-07 1986-08-26 Hoechst-Roussel Pharmaceuticals Inc. 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents
US4794110A (en) * 1987-07-20 1988-12-27 Hoechst-Roussel Pharmaceuticals, Inc. 5-Aryl-11-substituted-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepined as analgesic and hypotensive agents
US4879382A (en) * 1988-07-25 1989-11-07 Hoechst-Roussel Pharmaceuticals, Inc. Pyrido(3,4-f)pyrrolo(1,2-b)(1,2,5)triazepines

Also Published As

Publication number Publication date
FI912499A7 (fi) 1991-11-26
EP0458331B1 (en) 1999-08-25
IL98231A0 (en) 1992-06-21
FI912499L (fi) 1991-11-26
MX25922A (es) 1993-10-01
NZ238238A (en) 1993-06-25
AU7621391A (en) 1991-11-28
HU207520B (en) 1993-04-28
DE69131546T2 (de) 2000-03-23
ES2135383T3 (es) 1999-11-01
HU911755D0 (en) 1991-12-30
CS157191A3 (en) 1992-01-15
KR100286405B1 (ko) 2001-04-16
CA2043229A1 (en) 1991-11-26
IE911788A1 (en) 1991-12-04
DE69131546D1 (de) 1999-09-30
PT97762B (pt) 1998-10-30
AU638572B2 (en) 1993-07-01
PL290405A1 (en) 1992-08-24
PT97762A (pt) 1992-02-28
ZA913951B (en) 1992-03-25
JP3090500B2 (ja) 2000-09-18
JPH04235186A (ja) 1992-08-24
KR910020018A (ko) 1991-12-19
EP0458331A1 (en) 1991-11-27
GR3031538T3 (en) 2000-01-31
ATE183746T1 (de) 1999-09-15
NO911998L (no) 1991-11-26
NO911998D0 (no) 1991-05-24
US5015637A (en) 1991-05-14
CA2043229C (en) 2003-02-11
HUT60744A (en) 1992-10-28
DK0458331T3 (da) 2000-03-13
FI912499A0 (fi) 1991-05-23

Similar Documents

Publication Publication Date Title
FI91401B (fi) Menetelmä terapeuttisesti aktiivisten substituoitujen 9-aminotetrahydroakriinien ja niille läheisten yhdisteiden valmistamiseksi
WO2019099402A1 (en) Therapeutic compounds and methods to treat infection
EP0892796B1 (en) Isatin derivatives as acetylcholinesterase inhibitors and analgesics
EP0258755A1 (en) Alpha-alkyl-4-amino-3-quinoline-methanols and 1-(4-aralkylamino-3-quinolinyl) alkanones, a process for their preparation and their use as medicaments
CN115151541A (zh) 新型化合物及其用途
JPH02184674A (ja) 新規化合物、その製法及びそれを含む医薬組成物
AU2013352463A1 (en) Triazolo-pyrazine derivatives useful in the treatment of disorders of the central nervous system
US4840947A (en) Antiinflammatory and analgesic piperidin-4-yl-tetracyclic benzodiazepines and use thereas
AU604786B2 (en) Fused heterocyclic tetrahydroaminoquinolinols and related compounds, a process for their preparation and their use as medicaments
IL98231A (en) Pyrido (3,4-b) pyrrolo (1,2-e) (1,4,5) oxadiazepines and related analogs, a process for their preparation and their use as medicaments
JPH07502485A (ja) ヒドロイソキノリン誘導体
US4897392A (en) 4H-indolo(1,2-d)(1,2,4)triazolo(4,3-A)(1,4)benzodiazepines
RU2012561C1 (ru) 3-(1,2-бензизоксазол-3-ил)-4-пиридамины, проявляющие анальгетическую, антихолинэстеразную и дерматологическую активность
TW202208374A (zh) 經取代三環醯胺類、其類似物及使用其之方法
EP0475352B1 (en) 3-(1H-Indazol-3-yl)-4-pyridinamines, a process and intermediates for their preparation and their use as medicaments
EP0197318B1 (en) Benzo[C]-1,5-naphthyridines, a process and intermediates for their preparation and their use as medicaments
EP0413300A1 (en) Pyrido [3,4-b][1,4] benzoxazepines, a process for their preparation and their use as medicaments
US3334086A (en) Thieno-pyrido-benzodiazepin-ones
US3433794A (en) Certain 7 - (2 - aminophenyl) - 4,5 - dihydro thieno(2,3-c)pyridines and derivatives thereof
HU198945B (en) Process for producing tricyclic pyridone derivatives and pharmaceutical compositions comprising same
AU662730B2 (en) Neuroprotectant agents
EP0119541A1 (en) Substituted 4,10-dihydro-10-oxothieno-benzoxepins, a process for their preparation and their use as medicaments
AU716997C (en) Isatin derivatives as acetylcholinesterase inhibitors and analgesics
US4914201A (en) Indolo[1,2-d][1,4]benzodiazepin-6(7H)-thiones
US3118906A (en) 3-substituted-3-pyrrolidinols

Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)