IL98473A - Liposome immunoassays for detection of antigens antibodies and haptens - Google Patents

Liposome immunoassays for detection of antigens antibodies and haptens

Info

Publication number: IL98473A
Authority: IL; Israel
Prior art keywords: liposomes; liposome; hapten; antibody; enmeshed
Prior art date: 1991-06-12

Application number

IL9847391A

Other languages

English (en)

Other versions

IL98473A0 (en

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-12

Filing date

1991-06-12

Publication date

1995-08-31

1991-06-12 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

1991-06-12 Priority to IL9847391A priority Critical patent/IL98473A/en

1992-06-11 Priority to DE69228720T priority patent/DE69228720D1/de

1992-06-11 Priority to EP92109828A priority patent/EP0518319B1/de

1992-06-12 Priority to JP4195826A priority patent/JPH06160389A/ja

1992-07-15 Publication of IL98473A0 publication Critical patent/IL98473A0/xx

1995-08-31 Publication of IL98473A publication Critical patent/IL98473A/en

Links

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VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 description 1
229940079593 drug Drugs 0.000 description 1
235000013345 egg yolk Nutrition 0.000 description 1
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230000002708 enhancing effect Effects 0.000 description 1
230000002255 enzymatic effect Effects 0.000 description 1
230000005284 excitation Effects 0.000 description 1
238000000684 flow cytometry Methods 0.000 description 1
MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 description 1
238000001506 fluorescence spectroscopy Methods 0.000 description 1
238000005558 fluorometry Methods 0.000 description 1
239000008103 glucose Substances 0.000 description 1
229940116332 glucose oxidase Drugs 0.000 description 1
235000019420 glucose oxidase Nutrition 0.000 description 1
125000001475 halogen functional group Chemical group 0.000 description 1
229960002897 heparin Drugs 0.000 description 1
229920000669 heparin Polymers 0.000 description 1
230000002209 hydrophobic effect Effects 0.000 description 1
230000001900 immune effect Effects 0.000 description 1
230000008105 immune reaction Effects 0.000 description 1
230000006872 improvement Effects 0.000 description 1
238000011065 in-situ storage Methods 0.000 description 1
239000003999 initiator Substances 0.000 description 1
230000000977 initiatory effect Effects 0.000 description 1
229940125396 insulin Drugs 0.000 description 1
230000002101 lytic effect Effects 0.000 description 1
239000012567 medical material Substances 0.000 description 1
239000012528 membrane Substances 0.000 description 1
244000005700 microbiome Species 0.000 description 1
238000000386 microscopy Methods 0.000 description 1
239000004005 microsphere Substances 0.000 description 1
230000037361 pathway Effects 0.000 description 1
WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 description 1
239000013612 plasmid Substances 0.000 description 1
239000003505 polymerization initiator Substances 0.000 description 1
OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 description 1
102000004196 processed proteins & peptides Human genes 0.000 description 1
WHMDPDGBKYUEMW-UHFFFAOYSA-N pyridine-2-thiol Chemical compound SC1=CC=CC=N1 WHMDPDGBKYUEMW-UHFFFAOYSA-N 0.000 description 1
238000004451 qualitative analysis Methods 0.000 description 1
238000012207 quantitative assay Methods 0.000 description 1
238000010791 quenching Methods 0.000 description 1
238000011084 recovery Methods 0.000 description 1
238000011160 research Methods 0.000 description 1
230000004044 response Effects 0.000 description 1
238000012552 review Methods 0.000 description 1
239000013049 sediment Substances 0.000 description 1
238000000926 separation method Methods 0.000 description 1
150000003384 small molecules Chemical class 0.000 description 1
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229940083466 soybean lecithin Drugs 0.000 description 1
238000002798 spectrophotometry method Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
230000008961 swelling Effects 0.000 description 1
125000003396 thiol group Chemical group [H]S* 0.000 description 1
229960000984 tocofersolan Drugs 0.000 description 1
229960004747 ubidecarenone Drugs 0.000 description 1
229960005356 urokinase Drugs 0.000 description 1
239000002076 α-tocopherol Substances 0.000 description 1
235000004835 α-tocopherol Nutrition 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/586—Liposomes, microcapsules or cells

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Cell Biology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Immunology (AREA)
Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

IL9847391A 1991-06-12 1991-06-12 Liposome immunoassays for detection of antigens antibodies and haptens IL98473A (en)

Priority Applications (4)

Application Number	Priority Date	Filing Date	Title
IL9847391A IL98473A (en)	1991-06-12	1991-06-12	Liposome immunoassays for detection of antigens antibodies and haptens
DE69228720T DE69228720D1 (de)	1991-06-12	1992-06-11	Liposome-Immunoassay zum Nachweis von Antigenen, Antikörpern und Haptenen
EP92109828A EP0518319B1 (de)	1991-06-12	1992-06-11	Liposome-Immunoassay zum Nachweis von Antigenen, Antikörpern und Haptenen
JP4195826A JPH06160389A (ja)	1991-06-12	1992-06-12	抗原、抗体およびハプテン検出用のリポソーム免疫検定法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IL9847391A IL98473A (en)	1991-06-12	1991-06-12	Liposome immunoassays for detection of antigens antibodies and haptens

Publications (2)

Publication Number	Publication Date
IL98473A0 IL98473A0 (en)	1992-07-15
IL98473A true IL98473A (en)	1995-08-31

Family

ID=11062538

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL9847391A IL98473A (en)	1991-06-12	1991-06-12	Liposome immunoassays for detection of antigens antibodies and haptens

Country Status (4)

Country	Link
EP (1)	EP0518319B1 (de)
JP (1)	JPH06160389A (de)
DE (1)	DE69228720D1 (de)
IL (1)	IL98473A (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5738868A (en) *	1995-07-18	1998-04-14	Lipogenics Ltd.	Liposome compositions and kits therefor

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2711974B2 (ja) *	1993-02-03	1998-02-10	日水製薬株式会社	免疫凝集反応試薬及び免疫分析方法
GB9617631D0 (en) *	1996-08-22	1996-10-02	Biovation Ltd	Signal amplification method
JP2001208754A (ja) *	2000-01-26	2001-08-03	Kazunori Kataoka	生物学的な被検体を検出するための組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4176174A (en) *	1974-07-19	1979-11-27	Burroughs Wellcome Co.	Viral antibody diagnostic test system
FR2538907A1 (fr) *	1982-09-15	1984-07-06	Braylan Paul	Reactif immunologique constitue par des antigenes ou des anticorps en forme de cellules des particules ou des molecules ancres sur des surfaces solides continues par des unions ioniques ou covalents
JPS60231609A (ja) *	1984-04-28	1985-11-18	Terumo Corp	リポソ−ム製剤
US4874710A (en) *	1986-02-20	1989-10-17	Becton Dickinson And Company	Assay and product in which binder and liposomes are supported on a solid support
JPS6319559A (ja) *	1986-07-11	1988-01-27	Fuji Photo Film Co Ltd	免疫分析方法
EP0301333A3 (de) *	1987-07-29	1992-07-01	Abbott Laboratories	Auf liposomen basierter, homogener Immunoassay für diagnostische Teste

1991
- 1991-06-12 IL IL9847391A patent/IL98473A/en not_active IP Right Cessation
1992
- 1992-06-11 DE DE69228720T patent/DE69228720D1/de not_active Expired - Lifetime
- 1992-06-11 EP EP92109828A patent/EP0518319B1/de not_active Expired - Lifetime
- 1992-06-12 JP JP4195826A patent/JPH06160389A/ja active Pending

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5738868A (en) *	1995-07-18	1998-04-14	Lipogenics Ltd.	Liposome compositions and kits therefor

Also Published As

Publication number	Publication date
EP0518319B1 (de)	1999-03-24
IL98473A0 (en)	1992-07-15
EP0518319A2 (de)	1992-12-16
JPH06160389A (ja)	1994-06-07
DE69228720D1 (de)	1999-04-29
EP0518319A3 (en)	1993-01-13

Legal Events

Date	Code	Title	Description
1997-09-30	KB	Patent renewed
2002-02-10	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
CA1175740A (en)	1984-10-09	Immunolabelled liposomes
US4605630A (en)	1986-08-12	Large-liposome agglutination reagent and method
FI81914B (fi)	1990-08-31	Lipidvesikel innehaollande detekterbart maerkningsaemne och dess anvaendning vid analys.
CA1264662A (en)	1990-01-23	Immunoliposome assay - methods and products
US7858397B2 (en)	2010-12-28	Dehydration/rehydration of derivatized, marker-loaded liposomes on a test device and method of use thereof
EP0091958A1 (de)	1983-10-26	Liposom-konjugate sowie diagnoseverfahren die diese verwenden
EP0212989B1 (de)	1992-02-19	Lipid-Vesikel die markierte Spezies enthalten und ihre analytische Benutzung
US4745074A (en)	1988-05-17	Blood-fluid composition for cell lysis system
EP0518319B1 (de)	1999-03-24	Liposome-Immunoassay zum Nachweis von Antigenen, Antikörpern und Haptenen
Monroe	1989	Novel liposome immunoassays for detecting antigens, antibodies, and haptens
JPH0355790B2 (de)	1991-08-26
NAKAMURA et al.	1989	A Liposome Immunoassay Based on a Chemiluminescense Reaction
US4806466A (en)	1989-02-21	Cell agglutination reagent comprising conjugates of antibody covalently bound to liposomes
Rongen et al.	1995	Biotinylated and streptavidinylated liposomes as labels in cytokine immunoassays
JPH02115A (ja)	1990-01-05	薬剤の担体としての並びに免疫分析および細胞／分子分別のミクロ浮選装置としての乳脂小球の使用法
WO1992007959A1 (en)	1992-05-14	Homogeneous membrane lytic immunoassay method utilizing contact sensitive liposome formulations
US4888288A (en)	1989-12-19	Vesicles resistant to enzyme lysis and use thereof in an enzyme assay
EP0258388A1 (de)	1988-03-09	Immunoliposomes testverfahren und erzeugnisse
JP3654732B2 (ja)	2005-06-02	免疫測定法
Badley et al.	2018	Phospholipids in diagnosis
JPH0544626B2 (de)	1993-07-06
Kung et al.	1989	Recent Developments in the use of Liposomes in in vitro Diagnostic Assays
Ho	1987	Target sensitive immunoliposomes: design and applications
JP2652881B2 (ja)	1997-09-10	免疫分析方法
Litchfield et al.	1985	Liposome-Entrapped Enzyme Mediated Immunoassays

IL98473A - Liposome immunoassays for detection of antigens antibodies and haptens - Google Patents

Info

Links

Classifications

Landscapes

Priority Applications (4)

Applications Claiming Priority (1)

Publications (2)

Family

ID=11062538

Family Applications (1)

Country Status (4)

Cited By (1)

Families Citing this family (3)

Family Cites Families (6)

Cited By (1)

Also Published As

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