IL99011A0 - 2-(9-fluorenonyl)-carbapenems and pharmaceutical compositions containing them - Google Patents

2-(9-fluorenonyl)-carbapenems and pharmaceutical compositions containing them

Info

Publication number
IL99011A0
IL99011A0 IL99011A IL9901191A IL99011A0 IL 99011 A0 IL99011 A0 IL 99011A0 IL 99011 A IL99011 A IL 99011A IL 9901191 A IL9901191 A IL 9901191A IL 99011 A0 IL99011 A0 IL 99011A0
Authority
IL
Israel
Prior art keywords
fluorenonyl
carbapenems
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
IL99011A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/561,541 external-priority patent/US5025007A/en
Priority claimed from US07/594,809 external-priority patent/US5144028A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IL99011A0 publication Critical patent/IL99011A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL99011A 1990-08-01 1991-07-30 2-(9-fluorenonyl)-carbapenems and pharmaceutical compositions containing them IL99011A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/561,541 US5025007A (en) 1990-08-01 1990-08-01 2-(9-fluorenonyl)-carbapenem antibacterial agents
US07/594,809 US5144028A (en) 1990-10-09 1990-10-09 2-(9-fluorenonyl)-carbapenem intermediates

Publications (1)

Publication Number Publication Date
IL99011A0 true IL99011A0 (en) 1992-07-15

Family

ID=27072673

Family Applications (1)

Application Number Title Priority Date Filing Date
IL99011A IL99011A0 (en) 1990-08-01 1991-07-30 2-(9-fluorenonyl)-carbapenems and pharmaceutical compositions containing them

Country Status (12)

Country Link
EP (1) EP0469844A1 (fr)
JP (1) JPH0798821B2 (fr)
KR (1) KR920004389A (fr)
AU (1) AU643308B2 (fr)
CA (1) CA2048279A1 (fr)
FI (1) FI913654A7 (fr)
IE (1) IE912708A1 (fr)
IL (1) IL99011A0 (fr)
MX (1) MX9100467A (fr)
NO (1) NO912979L (fr)
NZ (1) NZ239187A (fr)
PT (1) PT98521A (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2142735A1 (fr) * 1993-06-18 1995-01-05 Tatsuyoshi Tanaka Derives du fluorenone, procede de preparation correspondant et agent de traitement ou de prevention de la degeneration du systeme nerveux central ou du systeme nerveux peripherique
US5451579A (en) * 1994-02-15 1995-09-19 Merck & Co., Inc. 1-β-methyl-carbapenem, compositions containing same and methods of use
JPWO2006025475A1 (ja) * 2004-09-03 2008-05-08 大日本住友製薬株式会社 新規なカルバペネム化合物
EP2135871A1 (fr) * 2008-06-18 2009-12-23 LEK Pharmaceuticals D.D. Nouveaux antibiotiques trinem et inhibiteurs de beta-lactamases
US9296752B2 (en) 2010-07-08 2016-03-29 Hans R. Pfaendler Fluorescent carbapenems

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543257A (en) * 1977-10-19 1985-09-24 Merck & Co., Inc. 1-Carba-2-penem-3-carboxylic acid
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
US4600713A (en) * 1979-12-03 1986-07-15 Merck & Co., Inc. 1-, 6- and 2-substituted-1-carba-2-penem-3-carboxylic acids
EP0277743A1 (fr) * 1987-02-02 1988-08-10 Merck & Co. Inc. 2-(Hétéroaryliumalkyl)phényl-carbapénèmes, comme agents antibactériens
US5025008A (en) * 1989-06-08 1991-06-18 Merck & Co., Inc. 2-(substituted-dibenzofuranyl and dibenzothienyl) carbapenem antibacterial agents

Also Published As

Publication number Publication date
KR920004389A (ko) 1992-03-27
CA2048279A1 (fr) 1992-02-02
NO912979L (no) 1992-02-03
NZ239187A (en) 1993-10-26
AU643308B2 (en) 1993-11-11
PT98521A (pt) 1992-06-30
FI913654A0 (fi) 1991-07-31
EP0469844A1 (fr) 1992-02-05
JPH05105681A (ja) 1993-04-27
IE912708A1 (en) 1992-02-12
FI913654L (fi) 1992-02-02
AU8151891A (en) 1992-02-06
JPH0798821B2 (ja) 1995-10-25
NO912979D0 (no) 1991-07-31
FI913654A7 (fi) 1992-02-02
MX9100467A (es) 1992-04-01

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