IN2004CH02621A - Low-cost production of peptides - Google Patents

Low-cost production of peptides

Info

Publication number
IN2004CH02621A
IN2004CH02621A IN2621CH2004A IN2004CH02621A IN 2004CH02621 A IN2004CH02621 A IN 2004CH02621A IN 2621CH2004 A IN2621CH2004 A IN 2621CH2004A IN 2004CH02621 A IN2004CH02621 A IN 2004CH02621A
Authority
IN
India
Prior art keywords
peptides
multimers
subject invention
amps
subject
Prior art date
Application number
Other languages
English (en)
Inventor
Joseph Krebs
Paul Zorner
Ian Tomlinson
Original Assignee
Dow Global Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies Inc filed Critical Dow Global Technologies Inc
Publication of IN2004CH02621A publication Critical patent/IN2004CH02621A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IN2621CH2004 2002-04-22 2004-11-22 Low-cost production of peptides IN2004CH02621A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37464402P 2002-04-22 2002-04-22

Publications (1)

Publication Number Publication Date
IN2004CH02621A true IN2004CH02621A (en) 2007-03-02

Family

ID=29251215

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2621CH2004 IN2004CH02621A (en) 2002-04-22 2004-11-22 Low-cost production of peptides

Country Status (11)

Country Link
US (1) US7595173B2 (fr)
EP (1) EP1501935B1 (fr)
JP (1) JP4472998B2 (fr)
KR (1) KR20050016362A (fr)
CN (1) CN100489114C (fr)
AT (1) ATE443767T1 (fr)
AU (1) AU2003228637B2 (fr)
CA (1) CA2482995C (fr)
DE (1) DE60329382D1 (fr)
IN (1) IN2004CH02621A (fr)
WO (1) WO2003089455A2 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
EP1692282B1 (fr) * 2003-11-19 2012-08-08 Pfenex, Inc. Systemes d'expression de proteine ameliores dans Pseudomonas fluorescens auxotrophe
BRPI0416807A (pt) 2003-11-21 2007-01-09 Dow Global Technologies Inc sistemas de expressão aperfeiçoados com secreção de sistema sec
CA2547511A1 (fr) * 2003-12-01 2005-07-28 Dow Global Technolgies Inc. Production de particules du type virus icosaedrique recombine chez des pseudomonades
KR101183720B1 (ko) 2004-01-16 2012-09-17 다우 글로벌 테크놀로지스 엘엘씨 슈도모나스 플루오레센스에서의 포유류 단백질의 발현
WO2005086667A2 (fr) 2004-02-27 2005-09-22 The Dow Chemical Company Production de peptides dans des cellules de plantes avec un rendement eleve
CN101031655A (zh) 2004-07-26 2007-09-05 陶氏环球技术公司 通过株工程改进蛋白表达的方法
WO2006076742A2 (fr) * 2005-01-16 2006-07-20 Georgia Tech Research Corporation Procedes et compositions pour accroitre la permeabilite membranaire
KR101491867B1 (ko) 2007-01-31 2015-02-10 피페넥스 인크. 증가된 발현을 위한 박테리아 리더 서열
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US8318481B2 (en) 2007-12-07 2012-11-27 Pfenex Inc. High copy number self-replicating plasmids in pseudomonas
WO2009094634A1 (fr) 2008-01-24 2009-07-30 Esperance Pharmaceuticals Produits de fusion recombinants à domaine lytique et leurs procédés de fabrication et d'utilisation
GB0815484D0 (en) 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
EP2429564A1 (fr) * 2009-05-15 2012-03-21 Basf Se Compositions pharmaceutiques contenant des peptides antifongiques
NZ615847A (en) * 2009-06-03 2014-11-28 Basf Se Recombinant production of peptides
US20120195872A1 (en) 2009-06-26 2012-08-02 Lysando Ag Antimicrobial agents
PL2445515T3 (pl) 2009-06-26 2016-10-31 Środki przeciwdrobnoustrojowe
EP2585606A4 (fr) 2010-06-26 2016-02-17 Virdia Ltd Mélanges de sucres, méthodes de production et d'utilisation associées
US8609621B2 (en) 2010-11-15 2013-12-17 E I Du Pont De Nemours And Company Acid-cleavable linkers exhibiting altered rates of acid hydrolysis
CN112400900A (zh) 2012-03-09 2021-02-26 韦斯塔隆公司 毒肽产生、植物中的肽表达和富含半胱氨酸的肽的组合
US11692016B2 (en) 2012-03-09 2023-07-04 Vestaron Corporation High gene expression yeast strain
KR20210090298A (ko) 2012-10-30 2021-07-19 에스퍼란스 파마슈티컬스, 인코포레이티드 항체/약물 컨쥬게이트 및 이의 사용 방법
KR101830792B1 (ko) * 2016-01-27 2018-02-21 건국대학교 산학협력단 항균 펩타이드를 포함하는 불용성 융합단백질 및 이를 이용한 항균 펩타이드의 제조 방법
US11535653B2 (en) * 2016-10-21 2022-12-27 Vestaron Corporation Cleavable peptides and insecticidal and nematicidal proteins comprising same
JP2019002696A (ja) * 2017-06-12 2019-01-10 日本電子株式会社 質量分析データ処理装置、質量分析システム及び質量分析データ処理方法
WO2020206056A1 (fr) 2019-04-04 2020-10-08 Greenvenus Llc Peptides et procédés de protection de plantes
CN110305890A (zh) * 2019-07-02 2019-10-08 河南城建学院 一种新型5种抗菌肽串联表达重组工程菌构建方法及其应用
WO2021216621A2 (fr) 2020-04-20 2021-10-28 Vestaron Corporation Polypeptides variants d'u1-agatoxine-ta1b stables à la protéolyse pour la lutte antiparasitaire
EP4444739A2 (fr) 2021-12-08 2024-10-16 Oakgrove Bio LLC Production biologique de peptides riches en histidine
CN115083176B (zh) * 2022-06-28 2024-05-10 浙江大学 一种基于多任务并行控制的网联自动车群串联排列实现方法
CN120958034A (zh) * 2023-02-23 2025-11-14 微肽技术有限公司 用于产生和纯化肽的方法和组合物
CN116333051A (zh) * 2023-03-09 2023-06-27 天津科技大学 一种抗菌肽改造体om19r原核表达制备方法及应用
US20260226101A1 (en) * 2023-10-30 2026-08-06 Ramakrishna Reddy ISANAKA Peptide with anti-inflammatory and anti-microbial activity

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2274344A (en) * 1939-01-06 1942-02-24 Kraft Cheese Company Package and method of making the same
GB1549167A (en) 1975-04-11 1979-08-01 Takeda Chemical Industries Ltd Method for producing aminoglycosidec anitibiotics
US5206154A (en) 1985-01-28 1993-04-27 Xoma Corporation Method of producing cecropins by microbiological techniques
US5861478A (en) 1987-07-06 1999-01-19 Helix Biomedix, Inc. Lytic peptides
DE3854476T2 (de) 1987-07-06 1996-04-04 Univ Louisiana State Inhibierung von eukaryotischen pathogenen und neoplasmen mit lytischen peptiden.
CA1327311C (fr) 1987-07-06 1994-03-01 Jesse M. Jaynes Polypeptides antimicrobiens therapeutiques, leurs methodes de preparation et leurs usages
US6132775A (en) 1987-08-11 2000-10-17 New York University Therapeutic uses of biologically active bactericidal/permeability-increasing protein fragments
US5128130A (en) 1988-01-22 1992-07-07 Mycogen Corporation Hybrid Bacillus thuringiensis gene, plasmid and transformed Pseudomonas fluorescens
US5055294A (en) 1988-03-03 1991-10-08 Mycogen Corporation Chimeric bacillus thuringiensis crystal protein gene comprising hd-73 and berliner 1715 toxin genes, transformed and expressed in pseudomonas fluorescens
US4853334A (en) 1988-04-27 1989-08-01 Microlife Technics, Inc. Method for the degradation of volatile chlorinated aliphatic hydrocarbons using pseudomonas fluorescens
JP2854872B2 (ja) 1989-02-02 1999-02-10 マルハ株式会社 カブトガニ血球膜由来抗菌性ペプタイドをリガンドとする不溶性担体
WO1990012866A1 (fr) 1989-04-10 1990-11-01 Louisiana State University And Agricultural And Mechanical College Peptides lytiques, leur emploi pour la croissance, l'infection et le cancer
US5627262A (en) 1989-07-05 1997-05-06 The Board Of Regents Of The University Of Oklahoma Method and composition for the treatment of septic shock
US5169760A (en) 1989-07-27 1992-12-08 Mycogen Corporation Method, vectors, and host cells for the control of expression of heterologous genes from lac operated promoters
DK0535060T3 (da) 1990-06-15 1995-07-17 Hoechst Schering Agrevo Gmbh Antifungisk polypeptid samt fremgangsmåde til dets fremstilling
JPH07108232B2 (ja) * 1990-10-09 1995-11-22 エム・ディ・リサーチ株式会社 ペプチド又は蛋白質の製造方法
AU668347B2 (en) 1990-11-21 1996-05-02 Torrey Pines Institute For Molecular Studies Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
US5348742A (en) 1991-05-24 1994-09-20 Ciba-Geigy Corporation Anti-pathogenic bacterial strains of Pseudomonas fluorescens
GB9115669D0 (en) 1991-07-19 1991-09-04 Sandoz Ltd Improvements in or relating to organic compounds
US5336757A (en) 1992-02-07 1994-08-09 Harbor Branch Oceanographic Institution, Inc. Antibacterial peptide and methods of use
US5593866A (en) * 1992-08-21 1997-01-14 The University Of British Columbia Cationic peptides and method for production
US5789377A (en) 1992-08-21 1998-08-04 University Of British Columbia Treatment of endotoxin-associated disorders with cationic peptides
US5496547A (en) * 1994-01-24 1996-03-05 Ciba-Geigy Corporation Pseudomonas biocontrol strains
US5527883A (en) 1994-05-06 1996-06-18 Mycogen Corporation Delta-endotoxin expression in pseudomonas fluorescens
US5716849A (en) 1994-06-08 1998-02-10 Novartis Finance Corporation Genes for the biosynthesis of soraphen
US5985617A (en) * 1997-02-18 1999-11-16 Liao; James C. Microorganisms and methods for overproduction of DAHP by cloned PPS gene
JPH08322556A (ja) 1995-03-28 1996-12-10 Nisshin Flour Milling Co Ltd 新規なシュードモナス・フルオレッセンス
US5711945A (en) 1995-05-11 1998-01-27 Regents Of The University Of Minnesota Pitch degradation with Pseudomonas fluorescens
US5944306A (en) * 1995-11-07 1999-08-31 Fuji Photo Film Co., Ltd. Package of thermal recording sheets and magazine
US5994306A (en) 1995-11-22 1999-11-30 Intrabiotics Pharmaceuticals, Inc. Fine-tuned protegrins
US6255279B1 (en) 1995-12-16 2001-07-03 Beiersdorf Ag Cosmetic preparations containing vertebrate proteins and having antibacterial, antimycotical and antiviral action
AUPN861496A0 (en) 1996-03-13 1996-04-04 Commonwealth Scientific And Industrial Research Organisation Lytic peptides
US5851802A (en) 1996-03-22 1998-12-22 Xoma Corporation Methods for recombinant microbial production of fusion proteins and BPI-derived peptides
ES2165557T3 (es) 1996-12-13 2002-03-16 Hoechst Ag Nuevo antibiotico, feglimicina, procedimiento para su preparacion y utilizacion.
AU6035398A (en) 1997-01-31 1998-08-25 Incyte Pharmaceuticals, Inc. Human c5a-like receptor
KR100263583B1 (ko) 1997-05-28 2000-08-01 박종헌 항균 펩타이드의 대량 제조방법 및 그에 유용한 플라즈미드 벡타
FR2766191B1 (fr) 1997-07-21 2000-11-10 Ifremer Peptides anti-microbiens de crustaces
ATE243221T1 (de) 1998-03-25 2003-07-15 Korea Advanced Inst Sci & Tech Neuartiges aus -i(parasilurus asotus) isoliertes antimikrobielles peptid und seine verwendung
KR100319529B1 (ko) 1998-06-09 2002-01-09 김일웅 펩타이드 항생물질의 대량 생산 방법 및 그에 유용한 유전자 구조물
US20020107174A1 (en) 1998-07-02 2002-08-08 Erik J. Paus Composition comprising endotoxin neutralizing protein and derivatives and uses thereof
JP2002530114A (ja) * 1998-11-20 2002-09-17 マイクロロジックス バイオテック,インコーポレイテッド 宿主細胞において抗菌カチオン性ペプチドを産生するための効率的な方法
AU1805200A (en) 1998-12-10 2000-06-26 Samyang Genex Corporation Method of separating basic peptide or basic protein
US6242219B1 (en) 1999-03-18 2001-06-05 Xoma (Us) Llc Methods for recombinant peptide production
AU2002306484A1 (en) 2002-02-13 2003-09-04 Dow Global Technologies Inc. Over-expression of extremozyme genes in pseudomonads and closely related bacteria

Also Published As

Publication number Publication date
AU2003228637A1 (en) 2003-11-03
CA2482995C (fr) 2013-01-29
CN1662657A (zh) 2005-08-31
JP4472998B2 (ja) 2010-06-02
JP2006504400A (ja) 2006-02-09
EP1501935B1 (fr) 2009-09-23
KR20050016362A (ko) 2005-02-21
WO2003089455A3 (fr) 2004-05-27
EP1501935A2 (fr) 2005-02-02
EP1501935A4 (fr) 2007-05-23
DE60329382D1 (de) 2009-11-05
WO2003089455A2 (fr) 2003-10-30
CA2482995A1 (fr) 2003-10-30
AU2003228637B2 (en) 2010-08-05
US20050227321A1 (en) 2005-10-13
US7595173B2 (en) 2009-09-29
ATE443767T1 (de) 2009-10-15
CN100489114C (zh) 2009-05-20

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