IN2012DN01850A - - Google Patents

Download PDF

Info

Publication number
IN2012DN01850A
IN2012DN01850A IN1850DEN2012A IN2012DN01850A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A IN 1850DEN2012 A IN1850DEN2012 A IN 1850DEN2012A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A
Authority
IN
India
Prior art keywords
separation
line
units
fluid
separation unit
Prior art date
Application number
Other languages
English (en)
Inventor
M Williams Alan
Kaletski Adam
Stack Lisa
G Go Daniel
Krasnansky John
A Wareheim David
Lin Bin
Original Assignee
Ge Healthcare Bio Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43779133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN01850(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ge Healthcare Bio Sciences filed Critical Ge Healthcare Bio Sciences
Publication of IN2012DN01850A publication Critical patent/IN2012DN01850A/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
IN1850DEN2012 2009-09-25 2010-09-20 IN2012DN01850A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/566,701 US9527010B2 (en) 2009-09-25 2009-09-25 Separation system and method
PCT/SE2010/051003 WO2011037522A1 (en) 2009-09-25 2010-09-20 Separation system and method

Publications (1)

Publication Number Publication Date
IN2012DN01850A true IN2012DN01850A (de) 2015-08-21

Family

ID=43779133

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1850DEN2012 IN2012DN01850A (de) 2009-09-25 2010-09-20

Country Status (7)

Country Link
US (1) US9527010B2 (de)
EP (1) EP2480305B1 (de)
JP (1) JP5749270B2 (de)
CN (1) CN102574026B (de)
AU (1) AU2010298768B2 (de)
IN (1) IN2012DN01850A (de)
WO (1) WO2011037522A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2480943B1 (de) * 2009-09-25 2017-07-12 GE Healthcare Bio-Sciences AB Verfahren und system zur herstellung flüssiger mischungen
MX2012009283A (es) * 2010-02-12 2012-09-07 Dsm Ip Assets Bv Purificacion de anticuerpo de una unidad.
ES2603396T3 (es) * 2010-07-30 2017-02-27 Pfizer Inc Purificación en tándem de proteínas
US20130109102A1 (en) * 2010-09-20 2013-05-02 Hiroyuki Yabe Liquid chromatography system and method for protein separation and purification
MX2013004720A (es) * 2010-11-01 2013-05-28 Dsm Ip Assets Bv Purificacion de anticuerpos mediante cromatografia de intercambio ionico de una uncia unidad.
AU2012269240B2 (en) * 2011-06-16 2016-01-21 Dpx Holdings B.V. Single unit chromatography antibody purification
US9096648B2 (en) * 2011-08-19 2015-08-04 Emd Millipore Corporation Methods of reducing level of one or more impurities in a sample during protein purification
EP2578286A1 (de) * 2011-10-04 2013-04-10 Merck Patent GmbH Verfahren und Vorrichtung zur chromatographischen Aufreinigung
RU2610386C2 (ru) * 2011-11-10 2017-02-09 Ф.Хоффманн-Ля Рош Аг Препаративная хроматографическая колоночная система
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
SG11201406407TA (en) 2012-06-29 2014-11-27 Emd Millipore Corp Methods for inactivating viruses during a protein purification process
ES2665645T3 (es) * 2013-05-06 2018-04-26 Sanofi Proceso multietapa continuo para purificar anticuerpos
CN103439433B (zh) * 2013-09-11 2015-06-10 青岛普仁仪器有限公司 免稀释作线性曲线的色谱仪及线性曲线测量方法
JPWO2015041218A1 (ja) * 2013-09-17 2017-03-02 株式会社カネカ 新規抗体精製方法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎＭｅｔｈｏｄａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ）、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎｍｅｔｈｏｄｕｓｉｎｇＣａｔｉｏｎＥｘｃｈａｎｇｅｒａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ）
ES2864721T3 (es) * 2014-02-07 2021-10-14 Cmc Biologics As Disposición y proceso continuo de un biorreactor para la producción y captura de un biopolímero
EP3105580B1 (de) 2014-02-14 2023-10-04 Cytiva Sweden AB Mehrstufiges automatisches reinigungssystem
JP6331485B2 (ja) * 2014-03-04 2018-05-30 株式会社島津製作所 液体クロマトグラフ及び液体クロマトグラフ分析方法
CN106661083A (zh) * 2014-05-02 2017-05-10 诺和诺德股份有限公司 集成的连续生物制造处理方法
US11835501B2 (en) 2015-07-13 2023-12-05 Sartorius Stedim Chromatography Systems Ltd. Optimizing operating binding capacity for a multiple column chromatography process
JP6579515B2 (ja) * 2015-08-10 2019-09-25 国立大学法人 岡山大学 アポｅ含有ｈｄｌの測定方法及び測定装置
DK3440518T3 (da) * 2016-04-04 2026-01-19 Boehringer Ingelheim Rcv Gmbh Realtids-overvågning af produktoprensning
GB201622343D0 (en) * 2016-12-29 2017-02-15 Ge Healthcare Bio Sciences Ab Method in bioprocess purification system
US11016110B2 (en) 2017-01-26 2021-05-25 Myriad Women's Health, Inc. Reagent delivery and waste management system
US11185830B2 (en) 2017-09-06 2021-11-30 Waters Technologies Corporation Fluid mixer
FR3073424B1 (fr) 2017-11-16 2022-03-25 Novasep Process Procede regule de separation d’un melange
GB201802593D0 (en) * 2018-02-16 2018-04-04 Fujifilm Diosynth Biotechnologies Uk Ltd Rig
KR102825164B1 (ko) * 2018-03-27 2025-06-26 브리스톨-마이어스 스큅 컴퍼니 자외선 신호를 사용한 단백질 농도의 실시간 모니터링
EP3546475A1 (de) 2018-03-27 2019-10-02 Sanofi Volldurchflussverfahren zur reinigung rekombinanter proteine
CN109453545A (zh) * 2018-12-20 2019-03-12 上海兆维科技发展有限公司 层析柱洗脱液的配液装置
BR112021013056A2 (pt) * 2019-02-11 2021-11-23 Bayer Ag Influência de uma cromatografia sequencial em tempo real
EP3763429A1 (de) * 2019-07-08 2021-01-13 Bayer Aktiengesellschaft Beeinflussung einer sequenziellen chromatografie in echtzeit
EP3693732A1 (de) * 2019-02-11 2020-08-12 Bayer Aktiengesellschaft Beeinflussung einer sequenziellen chromatographie in echtzeit
EP3699697A1 (de) * 2019-02-25 2020-08-26 Bayer Aktiengesellschaft Automatisierte gleichzeitige prozesssteuerung
FR3099066B1 (fr) 2019-07-26 2021-08-13 Novasep Process Procédé de purification d’une substance cible avec inactivation virale
CN119715878A (zh) 2019-08-12 2025-03-28 沃特世科技公司 用于色谱系统的混合器
GB201911685D0 (en) 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying monoclonal antibodies
GB201911686D0 (en) * 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying target substances
MX2022003513A (es) * 2019-09-23 2022-07-11 Genzyme Corp Medicion de atributos de calidad de producto.
JP7388206B2 (ja) * 2020-01-22 2023-11-29 株式会社島津製作所 液体クロマトグラフおよび分析方法
CN113663364B (zh) * 2020-05-14 2025-02-21 佛山汉腾生物科技有限公司 层析装置
EP4179310B1 (de) 2020-07-07 2025-07-30 Waters Technologies Corporation Mischer für die flüssigkeitschromatographie
EP4179311B1 (de) 2020-07-07 2025-07-30 Waters Technologies Corporation Kombinationsmischeranordnung zur rauschminderung in der flüssigkeitschromatographie
US11802818B2 (en) * 2020-09-17 2023-10-31 Computational International LLC System and method for monitoring for the presence of elements
CN116194767A (zh) 2020-09-22 2023-05-30 沃特世科技公司 连续流混合器
JP2022091322A (ja) 2020-12-09 2022-06-21 株式会社島津製作所 液体クロマトグラフのｐＨ管理システムおよびプログラム
WO2022245566A1 (en) 2021-05-20 2022-11-24 Waters Technologies Corporation Equal dispersion split-flow mixer
EP4359118A1 (de) 2021-06-23 2024-05-01 Waters Technologies Corporation Passiver lösungsmittelmischer für die flüssigkeitschromatographie
US20250179466A1 (en) * 2022-03-03 2025-06-05 Chromacon Ag Chromatographic purification method and uses thereof
CN114797173A (zh) * 2022-04-10 2022-07-29 南通星中细胞工程有限公司 一种用于外泌体的高效制备装置及制备方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3918907A (en) * 1973-10-29 1975-11-11 Beckman Instruments Inc Micro automatic amino acid analysis process and system
US4246101A (en) * 1978-12-28 1981-01-20 Pure Cycle Corporation Water recycling system
US4762796A (en) 1981-10-05 1988-08-09 Exxon Research And Engineering Company pH control of a process stream
JPS62255865A (ja) 1986-04-28 1987-11-07 Hitachi Ltd 液体クロマトグラフ
US4840730A (en) * 1986-07-25 1989-06-20 Sepragen Corporation Chromatography system using horizontal flow columns
JP2581568B2 (ja) 1987-10-08 1997-02-12 株式会社日立製作所 イオンクロマトグラフイ装置
US5114576A (en) * 1990-02-15 1992-05-19 Trineos Prevention of contaminants buildup in captured and recirculated water systems
JP3175941B2 (ja) * 1991-03-28 2001-06-11 パーセプティブ バイオシステムズ インコーポレイテッド クロマトグラフ溶出液の減法に依るオンライン生成物確認方法及び装置
US5792371A (en) 1996-08-22 1998-08-11 Iosolutions Incorporated Method of disinfecting water with iodine species
US6799883B1 (en) 1999-12-20 2004-10-05 Air Liquide America L.P. Method for continuously blending chemical solutions
US20030170810A1 (en) * 2001-09-18 2003-09-11 Masoud Vedadi Methods and apparatuses for purification
WO2003083467A2 (de) 2002-03-28 2003-10-09 Siemens Aktiengesellschaft Gaschromatograph und verfahren zur gaschromatographischen analyse eines stoffgemischs
JP2004077329A (ja) 2002-08-20 2004-03-11 Japan Organo Co Ltd クロマト分離装置
US6972415B2 (en) * 2002-09-26 2005-12-06 R-Can Environmental Inc. Fluid treatment system with UV sensor and intelligent driver
US20040124253A1 (en) * 2002-10-17 2004-07-01 Bergwin Gregory A. Injection apparatus for irrigation system
EP1567659A4 (de) 2002-11-18 2006-08-09 Taurus Hsa Llc Verfahren zum kontinuierlichen,automatischen mischen von lösungen aus säuren und basen
WO2004103519A2 (en) 2003-05-16 2004-12-02 Cryobiophysica, Inc. External gradient chromatofocusing
US7632410B2 (en) * 2003-08-21 2009-12-15 Christopher Heiss Universal water purification system
WO2005040787A1 (en) 2003-10-17 2005-05-06 Ge Healthcare Bio-Sciences Ab Chromatography system, method and software for the separation of biomolecules
US8271139B2 (en) 2003-10-17 2012-09-18 Asahi Kasei Bioprocess, Inc. Multi-stage accurate blending system and method
US7072742B1 (en) 2003-10-17 2006-07-04 Technikrom, Inc. Accurate blending module and method
WO2005111599A1 (en) * 2004-05-17 2005-11-24 Firmenich Sa New multidimensional gas chromatography apparatus and analyte transfer procedure using a multiple-cool strand interface
GB0624707D0 (en) * 2004-05-21 2007-01-17 Waters Investments Ltd Closed loop flow control of a hplc constant flow pump to enable low-flow operation
US7642306B2 (en) 2004-06-25 2010-01-05 Johns Manville Control of pH in formaldehyde-free binder systems
EP1807101B1 (de) 2004-09-30 2016-04-13 Bayer Healthcare LLC Geräte und verfahren zur integriertenkontinuierlichen herstellung von biologischen molekülen
US8123949B2 (en) * 2005-01-20 2012-02-28 Waters Technologies Corporation Methods for separating compounds
EP1716900A1 (de) * 2005-04-29 2006-11-02 Eidgenössische Technische Hochschule Zürich Verfahren und Vorrichtung zur chromatographischen Reinigung
EP1775001A1 (de) 2005-10-13 2007-04-18 Xendo Holding B.V. Vorrichtung für chromatographische Trennungen
JP4939910B2 (ja) * 2006-11-29 2012-05-30 株式会社東芝 マイクロ化学分析システム及びマイクロ化学分析装置
AU2007351639B2 (en) 2007-04-17 2012-12-13 Sartorius Stedim Chromatography Systems Ltd. Method and device for continuous membrane adsorption
GB0709109D0 (en) 2007-05-11 2007-06-20 Enpar Technologies Inc Wastewater ammonium extraction and electrolytic conversion to nitrogen gas
US20090149638A1 (en) * 2007-10-03 2009-06-11 Ley Arthur C Systems and methods for purifying proteins
US20110105725A1 (en) 2008-05-15 2011-05-05 Novo Nordisk A/S Antibody purification process
WO2010124159A1 (en) 2009-04-23 2010-10-28 Xcellerex, Inc. System and method for variable speed feedback control chromatography loading

Also Published As

Publication number Publication date
EP2480305A4 (de) 2014-07-02
AU2010298768A1 (en) 2012-03-15
US20110073548A1 (en) 2011-03-31
CN102574026A (zh) 2012-07-11
JP5749270B2 (ja) 2015-07-15
JP2013506127A (ja) 2013-02-21
EP2480305A1 (de) 2012-08-01
US9527010B2 (en) 2016-12-27
CN102574026B (zh) 2015-10-07
AU2010298768B2 (en) 2015-07-02
WO2011037522A1 (en) 2011-03-31
EP2480305B1 (de) 2020-10-28

Similar Documents

Publication Publication Date Title
IN2012DN01850A (de)
SG10201803601SA (en) Methods and systems for processing a cell culture
WO2011150604A8 (zh) 净化饮水装置及其控制方法
WO2015175679A3 (en) Process control systems and methods for use with filters and filtration processes
EA201101427A1 (ru) Настраиваемые устройства регулирования потока для использования при добыче углеводородов
MX2015002556A (es) Sistema y metodo para tratamiento de agua.
MY167267A (en) Downhole fluid flow control system having a fluidic module with a bridge network and method for use of same
BRPI0913857A2 (pt) sistema de drenagem de líquido
MX2023000906A (es) Un aparato de purificacion de agua y un metodo para controlar por lo menos una propiedad del fluido en un aparato de purificacion de agua.
NZ594012A (en) A gravity fed water treatment system comprising a foam filter element, a biological layer and a restriction orifice to limit the flow of water through the system
MX2013010347A (es) Sistemas y metodos para controlar el flujo de fluidos corporales.
GB201219919D0 (en) Flushing system
ATE527874T1 (de) Strömungstechnische ausrichtungs- und sortiervorrichtung für pflanzenembryos
WO2008143638A3 (en) Pumping and flow control in systems including microfluidic systems
MY157460A (en) Filter comprising a halogen release system and chitosan
WO2020005069A3 (en) A mobile system for continuous, automatic, online monitoring of water quality and particle sampling in a drinking water distribution network
WO2012081027A3 (en) Filtration system and components there for
ZA201103186B (en) Method for the filtration of a bioreactor liquid from a bioreactor;cross-flow membrane module,and bioreactor membrane system
PH12017500312B1 (en) Anaerobic membrane bioreactor system
BRPI0512907A (pt) dispositivo de purificação, suplemento e método de purificação de um lìquido
MA34044B1 (fr) Dispositif pour filtrer et separer des milieux en ecoulement
WO2013156988A8 (en) Effecting high recovery desalination with pressure driven membranes
WO2007007341A3 (en) Continuous membrane filter separation of suspended particles in closed circuit
WO2012120265A3 (en) Apparatus for saving water
MX2010000534A (es) Filtracion por flujo tangencial variable.