IN2012DN01850A - - Google Patents
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- Publication number
- IN2012DN01850A IN2012DN01850A IN1850DEN2012A IN2012DN01850A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A IN 1850DEN2012 A IN1850DEN2012 A IN 1850DEN2012A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A
- Authority
- IN
- India
- Prior art keywords
- separation
- line
- units
- fluid
- separation unit
- Prior art date
Links
- 238000000926 separation method Methods 0.000 abstract 11
- 239000012530 fluid Substances 0.000 abstract 4
- 230000007613 environmental effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/24—Automatic injection systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/566,701 US9527010B2 (en) | 2009-09-25 | 2009-09-25 | Separation system and method |
| PCT/SE2010/051003 WO2011037522A1 (fr) | 2009-09-25 | 2010-09-20 | Système et procédé de séparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN01850A true IN2012DN01850A (fr) | 2015-08-21 |
Family
ID=43779133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1850DEN2012 IN2012DN01850A (fr) | 2009-09-25 | 2010-09-20 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9527010B2 (fr) |
| EP (1) | EP2480305B1 (fr) |
| JP (1) | JP5749270B2 (fr) |
| CN (1) | CN102574026B (fr) |
| AU (1) | AU2010298768B2 (fr) |
| IN (1) | IN2012DN01850A (fr) |
| WO (1) | WO2011037522A1 (fr) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9327212B2 (en) * | 2009-09-25 | 2016-05-03 | Ge Healthcare Bio-Sciences Ab | Method and system for preparation of liquid mixtures |
| CN102762585B (zh) * | 2010-02-12 | 2016-01-20 | DPx控股有限公司 | 单一单元抗体纯化 |
| US9428546B2 (en) * | 2010-07-30 | 2016-08-30 | Pfizer Inc. | Tandem purification of proteins |
| US20130109102A1 (en) * | 2010-09-20 | 2013-05-02 | Hiroyuki Yabe | Liquid chromatography system and method for protein separation and purification |
| AU2011325341B2 (en) * | 2010-11-01 | 2015-12-17 | Dpx Holdings B.V. | Single unit ion exchange chromatography antibody purification |
| US20140187749A1 (en) * | 2011-06-16 | 2014-07-03 | Dsm Ip Assets B.V. | Single unit chromatography antibody purification |
| US9096648B2 (en) * | 2011-08-19 | 2015-08-04 | Emd Millipore Corporation | Methods of reducing level of one or more impurities in a sample during protein purification |
| EP2578286A1 (fr) | 2011-10-04 | 2013-04-10 | Merck Patent GmbH | Procédé et appareil de purification chromatographique |
| JP6158819B2 (ja) * | 2011-11-10 | 2017-07-05 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 分取カラムクロマトグラフィシステム |
| WO2013075740A1 (fr) | 2011-11-23 | 2013-05-30 | Sanofi | Procédé de purification d'anticorps |
| WO2014004103A1 (fr) * | 2012-06-29 | 2014-01-03 | Emd Millipore Corporation | Méthodes permettant d'inactiver des virus lors d'un procédé de purification de protéines |
| EP3301115B1 (fr) * | 2013-05-06 | 2021-11-10 | Sanofi | Procedes continue en plusieurs etapes destine a la purification des anticorps |
| CN103439433B (zh) * | 2013-09-11 | 2015-06-10 | 青岛普仁仪器有限公司 | 免稀释作线性曲线的色谱仪及线性曲线测量方法 |
| JPWO2015041218A1 (ja) * | 2013-09-17 | 2017-03-02 | 株式会社カネカ | 新規抗体精製方法及びそれから得られる抗体(NovelAntibodyPurificationMethodandAntibodyobtainedtherefrom)、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体(NovelAntibodyPurificationmethodusingCationExchangerandAntibodyobtainedtherefrom) |
| US11286292B2 (en) * | 2014-02-07 | 2022-03-29 | Cmc Biologics A/S | Bioreactor arrangement and continuous process for producing and capturing a biopolymer |
| JP6612242B2 (ja) * | 2014-02-14 | 2019-11-27 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 自動化された多段階精製システム及び多段階クロマトグラフィー精製方法 |
| JP6331485B2 (ja) * | 2014-03-04 | 2018-05-30 | 株式会社島津製作所 | 液体クロマトグラフ及び液体クロマトグラフ分析方法 |
| US20170058308A1 (en) * | 2014-05-02 | 2017-03-02 | Novo Nordisk A/S | Integrated continuous biomanufacturing process |
| US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
| JP6579515B2 (ja) * | 2015-08-10 | 2019-09-25 | 国立大学法人 岡山大学 | アポe含有hdlの測定方法及び測定装置 |
| KR102344339B1 (ko) * | 2016-04-04 | 2021-12-28 | 베링거 인겔하임 에르체파우 게엠베하 운트 코 카게 | 제제 정제의 실시간 모니터링 |
| GB201622343D0 (en) * | 2016-12-29 | 2017-02-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| WO2018140485A1 (fr) * | 2017-01-26 | 2018-08-02 | Counsyl, Inc. | Système de distribution de réactifs et de gestion des déchets |
| US11185830B2 (en) | 2017-09-06 | 2021-11-30 | Waters Technologies Corporation | Fluid mixer |
| FR3073424B1 (fr) | 2017-11-16 | 2022-03-25 | Novasep Process | Procede regule de separation d’un melange |
| GB201802593D0 (en) * | 2018-02-16 | 2018-04-04 | Fujifilm Diosynth Biotechnologies Uk Ltd | Rig |
| CN120943884A (zh) * | 2018-03-27 | 2025-11-14 | 百时美施贵宝公司 | 使用紫外线信号实时监测滴度 |
| EP3546475A1 (fr) | 2018-03-27 | 2019-10-02 | Sanofi | Processus d'écoulement intégral pour purifier des protéines recombinées |
| CN109453545A (zh) * | 2018-12-20 | 2019-03-12 | 上海兆维科技发展有限公司 | 层析柱洗脱液的配液装置 |
| EP3763429A1 (fr) * | 2019-07-08 | 2021-01-13 | Bayer Aktiengesellschaft | Influence d'une chromatographie séquentielle en temps réel |
| EP3693732A1 (fr) * | 2019-02-11 | 2020-08-12 | Bayer Aktiengesellschaft | Influence d'une chromatographie séquentielle en temps réel |
| KR20210127702A (ko) * | 2019-02-11 | 2021-10-22 | 바이엘 악티엔게젤샤프트 | 실시간 순차적 크로마토그래피에 대한 영향 |
| EP3699697A1 (fr) * | 2019-02-25 | 2020-08-26 | Bayer Aktiengesellschaft | Commande de processus simultané et automatisé |
| FR3099066B1 (fr) | 2019-07-26 | 2021-08-13 | Novasep Process | Procédé de purification d’une substance cible avec inactivation virale |
| CN114207433B (zh) | 2019-08-12 | 2025-01-14 | 沃特世科技公司 | 用于色谱系统的混合器 |
| GB201911685D0 (en) * | 2019-08-15 | 2019-10-02 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process for purifying monoclonal antibodies |
| GB201911686D0 (en) | 2019-08-15 | 2019-10-02 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process for purifying target substances |
| CA3151967A1 (fr) * | 2019-09-23 | 2021-04-01 | Marina Hincapie | Mesure d'attribut de qualite de produit |
| JP7388206B2 (ja) * | 2020-01-22 | 2023-11-29 | 株式会社島津製作所 | 液体クロマトグラフおよび分析方法 |
| CN113663364B (zh) * | 2020-05-14 | 2025-02-21 | 佛山汉腾生物科技有限公司 | 层析装置 |
| US11898999B2 (en) | 2020-07-07 | 2024-02-13 | Waters Technologies Corporation | Mixer for liquid chromatography |
| WO2022010666A1 (fr) | 2020-07-07 | 2022-01-13 | Waters Technologies Corporation | Agencement de mélangeur combiné pour la réduction de bruit en chromatographie en phase fluide |
| TW202227797A (zh) * | 2020-09-17 | 2022-07-16 | 美商計算國際有限公司 | 用於監測元素的存在之系統和方法 |
| EP4217729B1 (fr) | 2020-09-22 | 2025-08-13 | Waters Technologies Corporation | Mélangeur à écoulement continu |
| JP2022091322A (ja) | 2020-12-09 | 2022-06-21 | 株式会社島津製作所 | 液体クロマトグラフのpH管理システムおよびプログラム |
| US12399158B2 (en) | 2021-05-20 | 2025-08-26 | Waters Technologies Corporation | Equal dispersion split-flow mixer |
| US12551858B2 (en) | 2021-06-23 | 2026-02-17 | Waters Technologies Corporation | Passive solvent mixer for liquid chromatography |
| WO2023165947A1 (fr) * | 2022-03-03 | 2023-09-07 | Chromacon Ag | Procédé de purification chromatographique et ses utilisations |
| CN114797173A (zh) * | 2022-04-10 | 2022-07-29 | 南通星中细胞工程有限公司 | 一种用于外泌体的高效制备装置及制备方法 |
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| US3918907A (en) * | 1973-10-29 | 1975-11-11 | Beckman Instruments Inc | Micro automatic amino acid analysis process and system |
| US4246101A (en) * | 1978-12-28 | 1981-01-20 | Pure Cycle Corporation | Water recycling system |
| US4762796A (en) | 1981-10-05 | 1988-08-09 | Exxon Research And Engineering Company | pH control of a process stream |
| JPS62255865A (ja) | 1986-04-28 | 1987-11-07 | Hitachi Ltd | 液体クロマトグラフ |
| US4840730A (en) * | 1986-07-25 | 1989-06-20 | Sepragen Corporation | Chromatography system using horizontal flow columns |
| JP2581568B2 (ja) | 1987-10-08 | 1997-02-12 | 株式会社日立製作所 | イオンクロマトグラフイ装置 |
| US5114576A (en) * | 1990-02-15 | 1992-05-19 | Trineos | Prevention of contaminants buildup in captured and recirculated water systems |
| EP0533909B1 (fr) * | 1991-03-28 | 1997-01-08 | Perseptive Biosystems, Inc. | Identification rapide de produits dans une phase fluide de chromatographie par soustraction |
| US5792371A (en) | 1996-08-22 | 1998-08-11 | Iosolutions Incorporated | Method of disinfecting water with iodine species |
| US6799883B1 (en) | 1999-12-20 | 2004-10-05 | Air Liquide America L.P. | Method for continuously blending chemical solutions |
| AU2002325755A1 (en) * | 2001-09-18 | 2003-04-01 | Affinium Pharmaceuticals, Inc. | Methods and apparatuses for purification |
| EP1488226B1 (fr) | 2002-03-28 | 2012-08-29 | Siemens Aktiengesellschaft | Chromatographe pour phase gazeuse pour l'analyse de gaz naturel |
| JP2004077329A (ja) * | 2002-08-20 | 2004-03-11 | Japan Organo Co Ltd | クロマト分離装置 |
| US6972415B2 (en) * | 2002-09-26 | 2005-12-06 | R-Can Environmental Inc. | Fluid treatment system with UV sensor and intelligent driver |
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| JP2006513170A (ja) | 2002-11-18 | 2006-04-20 | トーラス エイチエスエイ エルエルシー | 酸および塩基から溶液を連続的に自動混合する方法 |
| EP1628729A2 (fr) | 2003-05-16 | 2006-03-01 | Cryobiophysica, Inc. | Chromatofocalisation a gradient externe |
| US7632410B2 (en) * | 2003-08-21 | 2009-12-15 | Christopher Heiss | Universal water purification system |
| US7072742B1 (en) | 2003-10-17 | 2006-07-04 | Technikrom, Inc. | Accurate blending module and method |
| US8271139B2 (en) | 2003-10-17 | 2012-09-18 | Asahi Kasei Bioprocess, Inc. | Multi-stage accurate blending system and method |
| WO2005040787A1 (fr) | 2003-10-17 | 2005-05-06 | Ge Healthcare Bio-Sciences Ab | Systeme de chromatographie, procede et logiciel pour la separation de biomolecules |
| EP1751537B1 (fr) | 2004-05-17 | 2019-07-10 | Firmenich SA | Appareil de chromatographie en phase gazeuse multidimensionnelle et procedure de transfert d'analyte au moyen d'une interface a brins de refroidissement multiples |
| JP4959565B2 (ja) * | 2004-05-21 | 2012-06-27 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 低流量動作を可能にするためのhplc定流量ポンプの閉ループ流量制御 |
| US7642306B2 (en) | 2004-06-25 | 2010-01-05 | Johns Manville | Control of pH in formaldehyde-free binder systems |
| PL1807101T3 (pl) | 2004-09-30 | 2016-11-30 | Urządzenia i sposoby do zintegrowanego wytwarzania cząsteczek biologicznych w sposób ciągły | |
| EP1871503B2 (fr) | 2005-01-20 | 2025-04-23 | Waters Technologies Corporation | Procedes de separation de composes |
| EP1716900A1 (fr) | 2005-04-29 | 2006-11-02 | Eidgenössische Technische Hochschule Zürich | Méthode et appareil pour purification par chromatographie |
| EP1775001A1 (fr) | 2005-10-13 | 2007-04-18 | Xendo Holding B.V. | Dispositif pour séparations chromatographiques |
| JP4939910B2 (ja) * | 2006-11-29 | 2012-05-30 | 株式会社東芝 | マイクロ化学分析システム及びマイクロ化学分析装置 |
| JP5140721B2 (ja) | 2007-04-17 | 2013-02-13 | イクスエンド、ホールディング、ベスローテン、フェンノートシャップ | 連続メンブレン吸着方法および装置 |
| GB0709109D0 (en) | 2007-05-11 | 2007-06-20 | Enpar Technologies Inc | Wastewater ammonium extraction and electrolytic conversion to nitrogen gas |
| WO2009045897A1 (fr) | 2007-10-03 | 2009-04-09 | Dyax Corp. | Systèmes et procédés de purification de protéines |
| EP2281000A2 (fr) | 2008-05-15 | 2011-02-09 | Novo Nordisk A/S | Procédé de purification d'anticorps |
| WO2010124159A1 (fr) | 2009-04-23 | 2010-10-28 | Xcellerex, Inc. | Système et procédé pour charger un système de chromatographie à commande par rétroaction à vitesse variable |
-
2009
- 2009-09-25 US US12/566,701 patent/US9527010B2/en active Active
-
2010
- 2010-09-20 JP JP2012530844A patent/JP5749270B2/ja active Active
- 2010-09-20 WO PCT/SE2010/051003 patent/WO2011037522A1/fr not_active Ceased
- 2010-09-20 CN CN201080043193.9A patent/CN102574026B/zh active Active
- 2010-09-20 IN IN1850DEN2012 patent/IN2012DN01850A/en unknown
- 2010-09-20 AU AU2010298768A patent/AU2010298768B2/en active Active
- 2010-09-20 EP EP10819116.4A patent/EP2480305B1/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9527010B2 (en) | 2016-12-27 |
| JP5749270B2 (ja) | 2015-07-15 |
| AU2010298768A1 (en) | 2012-03-15 |
| WO2011037522A1 (fr) | 2011-03-31 |
| EP2480305A4 (fr) | 2014-07-02 |
| CN102574026A (zh) | 2012-07-11 |
| US20110073548A1 (en) | 2011-03-31 |
| EP2480305B1 (fr) | 2020-10-28 |
| CN102574026B (zh) | 2015-10-07 |
| AU2010298768B2 (en) | 2015-07-02 |
| JP2013506127A (ja) | 2013-02-21 |
| EP2480305A1 (fr) | 2012-08-01 |
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