IN2012DN02642A - - Google Patents
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- Publication number
- IN2012DN02642A IN2012DN02642A IN2642DEN2012A IN2012DN02642A IN 2012DN02642 A IN2012DN02642 A IN 2012DN02642A IN 2642DEN2012 A IN2642DEN2012 A IN 2642DEN2012A IN 2012DN02642 A IN2012DN02642 A IN 2012DN02642A
- Authority
- IN
- India
- Prior art keywords
- cells
- oncogene
- differentiation stage
- present
- desired differentiation
- Prior art date
Links
- 230000004069 differentiation Effects 0.000 abstract 4
- 238000004519 manufacturing process Methods 0.000 abstract 3
- 108700020796 Oncogene Proteins 0.000 abstract 2
- 230000026969 oncogene-induced senescence Effects 0.000 abstract 2
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0641—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0644—Platelets; Megakaryocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/48—Regulators of apoptosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009213645 | 2009-09-15 | ||
| PCT/JP2010/065903 WO2011034073A1 (ja) | 2009-09-15 | 2010-09-15 | 分化細胞の新規製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN02642A true IN2012DN02642A (es) | 2015-09-11 |
Family
ID=43758674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2642DEN2012 IN2012DN02642A (es) | 2009-09-15 | 2010-09-15 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9200254B2 (es) |
| EP (2) | EP3159001B1 (es) |
| JP (4) | JP5791191B2 (es) |
| KR (2) | KR101667834B1 (es) |
| CN (2) | CN105385659B (es) |
| AU (1) | AU2010296415B2 (es) |
| BR (2) | BR112012005710B1 (es) |
| CA (1) | CA2774193C (es) |
| DK (2) | DK3159001T3 (es) |
| ES (2) | ES2664194T3 (es) |
| IN (1) | IN2012DN02642A (es) |
| RU (2) | RU2661107C1 (es) |
| WO (1) | WO2011034073A1 (es) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5861191B2 (ja) * | 2010-09-30 | 2016-02-16 | 国立大学法人 熊本大学 | ミエロイド系血液細胞の製造方法 |
| WO2012157586A1 (ja) * | 2011-05-13 | 2012-11-22 | 国立大学法人東京大学 | 多核化巨核球細胞、及び血小板の製造方法 |
| KR102031386B1 (ko) | 2011-10-03 | 2019-10-11 | 닛산 가가쿠 가부시키가이샤 | 다능성 간세포로부터의 거핵구 및/또는 혈소판의 제조 방법 |
| GB201210857D0 (en) | 2012-06-19 | 2012-08-01 | Cambridge Entpr Ltd | Transcription factor mediated programming towards megakaryocytes |
| CA2896053A1 (en) | 2012-12-21 | 2014-06-26 | Ocata Therapeutics, Inc. | Methods for production of platelets from pluripotent stem cells and compositions thereof |
| JP6495658B2 (ja) * | 2013-02-08 | 2019-04-03 | 国立大学法人京都大学 | 巨核球及び血小板の製造方法 |
| WO2014168255A1 (ja) * | 2013-04-12 | 2014-10-16 | 国立大学法人京都大学 | 巨核球の成熟化促進物質 |
| WO2014171486A1 (ja) | 2013-04-17 | 2014-10-23 | 日産化学工業株式会社 | 培地組成物及び当該培地組成物を用いた赤血球の製造方法 |
| EP3760711A1 (en) * | 2013-05-15 | 2021-01-06 | University Of Rochester | Human extensively self-renewing erythroblasts (esre) |
| US10112977B2 (en) | 2014-06-23 | 2018-10-30 | Toagosei Co., Ltd. | Peptide for inducing multinucleation in cells, and use therefor |
| RU2750740C2 (ru) * | 2015-03-09 | 2021-07-02 | Мегакарион Корпорейшн | Способ получения культуры, содержащей мегакариоциты, и способ получения тромбоцитов с ее применением |
| RU2730034C2 (ru) * | 2015-04-14 | 2020-08-14 | Киото Юниверсити | Способ получения клона стволовых клеток, пригодного для индуцирования дифференцировки в соматические клетки |
| KR20160129609A (ko) | 2015-04-30 | 2016-11-09 | 삼성전자주식회사 | Ｂｒａｆ 저해제를 포함하는 세포 또는 개체의 노화를 감소시키기 위한 조성물 및 그의 용도 |
| ES2833357T3 (es) * | 2015-11-02 | 2021-06-15 | Megakaryon Corp | Procedimiento de preparación de plaquetas con un dispositivo de agitación recíproca |
| WO2017131228A1 (ja) | 2016-01-29 | 2017-08-03 | 国立大学法人京都大学 | 血小板産生促進剤のスクリーニング方法 |
| JP6879511B2 (ja) | 2016-01-29 | 2021-06-02 | 国立大学法人京都大学 | 血小板産生促進剤及びそれを用いた血小板の製造方法 |
| WO2018164040A1 (ja) | 2017-03-06 | 2018-09-13 | 国立大学法人京都大学 | 血小板の製造方法 |
| FR3068366B1 (fr) * | 2017-06-30 | 2023-11-24 | Francais Du Sang Ets | Procede de production de progeniteurs erythroides |
| ES3063930T3 (en) | 2017-07-07 | 2026-04-21 | Univ Kyoto | Platelet production method and apparatus and method for determining operating conditions in platelet production apparatus |
| EP3680325B1 (en) | 2017-09-19 | 2026-02-18 | Megakaryon Corporation | Platelet production method, platelet preparation production method, and blood preparation production method |
| WO2019059235A1 (ja) | 2017-09-19 | 2019-03-28 | 株式会社メガカリオン | 精製血小板の製造方法、血小板製剤の製造方法、血液製剤の製造方法、血小板保存液、血小板保存剤および血小板の保存方法 |
| JP2021509812A (ja) | 2018-01-05 | 2021-04-08 | プレートレット バイオジェネシス， インコーポレイテッド | 巨核球を産生するための組成物および方法 |
| EP3813853A4 (en) | 2018-06-29 | 2022-04-06 | Platelet Biogenesis, Inc. | DELIVERY COMPOSITIONS AND METHODS OF USE |
| US20200268839A1 (en) * | 2019-02-25 | 2020-08-27 | National Yang-Ming University | Composition for treating pulmonary fibrosis and emphysema and therapeutic method using the same |
| EP3963082A4 (en) * | 2019-05-01 | 2023-01-04 | Immunebridge Inc. | Methods of making oligopotent and unipotent precursors |
| JP7058431B2 (ja) * | 2019-12-12 | 2022-04-22 | 国立大学法人千葉大学 | 巨核球および血小板を含む凍結乾燥製剤 |
| EP4063489A4 (en) | 2019-12-13 | 2024-02-28 | Megakaryon Corporation | COMPOSITION AND USE THEREOF |
| EP4238572A4 (en) | 2020-10-27 | 2024-10-16 | Nagasaki University | Osteogenic composition and use thereof |
| JP7716851B2 (ja) * | 2020-12-28 | 2025-08-01 | イビデン株式会社 | 凍結保存液 |
| US20240352418A1 (en) | 2021-06-18 | 2024-10-24 | Megakaryon Corporation | Method for producing multinucleated megakaryocyte with enhanced platelet production capability, method for producing platelets, method for producing platelet preparation, and method for producing blood preparation |
| EP4365283A4 (en) | 2021-06-30 | 2025-06-11 | National University Corporation Chiba University | Methods for improving the proliferative properties of common myeloid progenitor cells (CMP) or myelocytic progenitor cells |
| WO2024010317A1 (ko) * | 2022-07-04 | 2024-01-11 | 주식회사 아트블러드 | 유전자 과발현 조합을 이용한 적혈구 분화능이 우수한 불멸화 적혈구전구세포주 확립, 이의 제조방법 및 용도 |
| JP2025534107A (ja) | 2022-10-18 | 2025-10-09 | ソングァン メディカル ファンデーション | 幹細胞から血小板前駆細胞への分化誘導用培地組成物及びそれを用いた分化方法 |
| CN120641558A (zh) | 2022-12-28 | 2025-09-12 | 国立大学法人千叶大学 | 细胞分化度的调节方法 |
| TW202444899A (zh) | 2023-04-03 | 2024-11-16 | 日商大塚製藥股份有限公司 | 巨核細胞之製造方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US572333A (en) | 1896-12-01 | Evaporating apparatus | ||
| JPH06508749A (ja) * | 1991-06-28 | 1994-10-06 | ニュー イングランド ディーコネス ホスピタル | 新規な巨核球分化因子を産生する分化した巨核球の一系統 |
| GB9502022D0 (en) * | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
| US5723333A (en) | 1995-02-10 | 1998-03-03 | Regents Of The University Of California | Human pancreatic cell lines: developments and uses |
| WO1996024669A1 (en) | 1995-02-10 | 1996-08-15 | The Regents Of The University Of California | Human pancreatic cell lines: developments and uses |
| US20050159378A1 (en) * | 2001-05-18 | 2005-07-21 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA) |
| CN100350040C (zh) * | 2002-09-27 | 2007-11-21 | 生物E股份有限公司 | 细胞分离组合物和方法 |
| JP3896482B2 (ja) * | 2002-10-07 | 2007-03-22 | 独立行政法人産業技術総合研究所 | 分化細胞の作製方法 |
| JP2004350601A (ja) | 2003-05-29 | 2004-12-16 | Tanabe Seiyaku Co Ltd | 霊長類動物の胚性幹細胞から造血系細胞への分化方法 |
| JP4706208B2 (ja) | 2004-08-27 | 2011-06-22 | 株式会社アイル | 造血幹細胞の製造方法 |
| JP2006141356A (ja) | 2004-11-24 | 2006-06-08 | Institute Of Physical & Chemical Research | Ｅｓ細胞から樹立された造血幹細胞 |
| IL296832A (en) | 2005-10-18 | 2022-11-01 | Nat Jewish Health | Process of preparing red blood cells using conditionally immortalized long-term hematopoietic stem cells and erythropoietin |
| JP2009514967A (ja) * | 2005-11-07 | 2009-04-09 | ザ ジェネラル ホスピタル コーポレーション | 幹細胞の加齢化を調節するための方法及び組成物 |
| US8048999B2 (en) * | 2005-12-13 | 2011-11-01 | Kyoto University | Nuclear reprogramming factor |
| US8058064B2 (en) | 2006-10-04 | 2011-11-15 | The University Of Tokyo | Sac-like structure enclosing hematopoietic progenitor cells produced from ES cells and method for preparing blood cells |
| KR101564044B1 (ko) * | 2007-10-31 | 2015-10-28 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 핵초기화 방법 |
| CN101492676B (zh) * | 2008-09-16 | 2011-02-16 | 中国科学院广州生物医药与健康研究院 | 用脑膜细胞生成诱导的多能性干细胞的方法及其用途 |
-
2010
- 2010-09-15 DK DK16202612.4T patent/DK3159001T3/da active
- 2010-09-15 CA CA2774193A patent/CA2774193C/en active Active
- 2010-09-15 KR KR1020127009225A patent/KR101667834B1/ko active Active
- 2010-09-15 DK DK10817186.9T patent/DK2500418T3/en active
- 2010-09-15 EP EP16202612.4A patent/EP3159001B1/en active Active
- 2010-09-15 BR BR112012005710A patent/BR112012005710B1/pt active IP Right Grant
- 2010-09-15 CN CN201510530896.9A patent/CN105385659B/zh not_active Expired - Fee Related
- 2010-09-15 EP EP10817186.9A patent/EP2500418B1/en active Active
- 2010-09-15 JP JP2011531940A patent/JP5791191B2/ja active Active
- 2010-09-15 CN CN201080042161.7A patent/CN102712906B/zh active Active
- 2010-09-15 BR BR122013008030A patent/BR122013008030B8/pt active IP Right Grant
- 2010-09-15 WO PCT/JP2010/065903 patent/WO2011034073A1/ja not_active Ceased
- 2010-09-15 US US13/496,321 patent/US9200254B2/en active Active
- 2010-09-15 KR KR1020167027550A patent/KR101834687B1/ko active Active
- 2010-09-15 AU AU2010296415A patent/AU2010296415B2/en active Active
- 2010-09-15 ES ES10817186.9T patent/ES2664194T3/es active Active
- 2010-09-15 ES ES16202612T patent/ES2725688T3/es active Active
- 2010-09-15 RU RU2016139042A patent/RU2661107C1/ru active
- 2010-09-15 RU RU2012114427/10A patent/RU2603094C2/ru active
- 2010-09-15 IN IN2642DEN2012 patent/IN2012DN02642A/en unknown
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2015
- 2015-02-13 JP JP2015026547A patent/JP2015130866A/ja active Pending
- 2015-08-03 JP JP2015153048A patent/JP6265437B2/ja active Active
- 2015-10-28 US US14/925,508 patent/US10087419B2/en active Active
-
2016
- 2016-11-29 JP JP2016231020A patent/JP6382917B2/ja active Active
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