IN2012DN03032A - - Google Patents

Download PDF

Info

Publication number: IN2012DN03032A
Authority: IN; India
Prior art keywords: receptor antagonist; arb; salts; manufacture; processes
Prior art date: 2009-10-27

Application number

Other languages

English (en)

Inventor

Gottfried Sedelmeier

Florian Andreas Rampf

Dominique Grimler

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-10-27

Filing date

2010-10-25

Publication date

2015-07-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41716392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN03032(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2010-10-25 Application filed by Novartis Ag filed Critical Novartis Ag

2015-07-31 Publication of IN2012DN03032A publication Critical patent/IN2012DN03032A/en

Links

229940125364 angiotensin receptor blocker Drugs 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
239000002333 angiotensin II receptor antagonist Substances 0.000 abstract 1
239000000400 angiotensin II type 1 receptor blocker Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000002464 receptor antagonist Substances 0.000 abstract 1
229940044551 receptor antagonist Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/32—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/32—Separation; Purification; Stabilisation; Use of additives
- C07C253/34—Separation; Purification
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)

IN3032DEN2012 2009-10-27 2010-10-25 IN2012DN03032A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP09174264A EP2316821A1 (fr)	2009-10-27	2009-10-27	Procédé pour la fabrication de composés organiques
PCT/EP2010/066041 WO2011051213A1 (fr)	2009-10-27	2010-10-25	Procédé de fabrication de composés organiques

Publications (1)

Publication Number	Publication Date
IN2012DN03032A true IN2012DN03032A (fr)	2015-07-31

Family

ID=41716392

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IN3032DEN2012 IN2012DN03032A (fr)	2009-10-27	2010-10-25

Country Status (24)

Country	Link
US (1)	US20120238761A1 (fr)
EP (2)	EP2316821A1 (fr)
JP (1)	JP2013508436A (fr)
KR (1)	KR20120098652A (fr)
CN (1)	CN102596899A (fr)
AR (1)	AR079104A1 (fr)
AU (1)	AU2010311636B2 (fr)
BR (1)	BR112012009815A2 (fr)
CA (1)	CA2777031A1 (fr)
CL (1)	CL2012001081A1 (fr)
CO (1)	CO6531487A2 (fr)
EC (1)	ECSP12011833A (fr)
IL (1)	IL219111A0 (fr)
IN (1)	IN2012DN03032A (fr)
MA (1)	MA33692B1 (fr)
MX (1)	MX2012005025A (fr)
NZ (1)	NZ599218A (fr)
PE (1)	PE20121501A1 (fr)
PH (1)	PH12012500677A1 (fr)
RU (1)	RU2012121591A (fr)
TN (1)	TN2012000154A1 (fr)
TW (1)	TW201124389A (fr)
WO (1)	WO2011051213A1 (fr)
ZA (1)	ZA201202490B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102321038B (zh) *	2011-07-11	2014-03-26	安徽省虹升生物科技有限公司	一种改进的制备缬沙坦方法
FR2981077B1 (fr) *	2011-10-11	2013-11-01	Michelin Soc Tech	Methode pour preparer un melange maitre d'elastomere dienique et de silice
EP3508479A4 (fr) *	2016-09-02	2020-02-19	Noratech Pharmaceuticals, Inc.	Formes cristallines de sel disodique de valsartan
CN110078640B (zh) *	2019-03-29	2022-04-05	浙江美诺华药物化学有限公司	一种缬沙坦中间体的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4874867A (en)	1987-05-22	1989-10-17	E. I. Du Pont De Nemours And Company	Tetrazole intermediates to antihypertensive compounds
EP0443983B1 (fr)	1990-02-19	1996-02-28	Ciba-Geigy Ag	Composés acylés
JPH04297466A (ja)	1990-06-22	1992-10-21	Nippon Shinyaku Co Ltd	テトラゾール誘導体及び医薬
GB9222700D0 (en) *	1992-10-29	1992-12-09	Smithkline Beecham Plc	Chemical compounds
GB0222056D0 (en)	2002-09-23	2002-10-30	Novartis Ag	Process for the manufacture of organic compounds
GB0316546D0 (en) *	2003-07-15	2003-08-20	Novartis Ag	Process for the manufacture of organic compounds
ITMI20032267A1 (it) *	2003-11-21	2005-05-22	Dinamite Dipharma S P A In Forma A Bbreviata Diph	Procdimento per la preparzione di valsartan e suoi intermedi
HRP20030965A2 (en) *	2003-11-24	2005-08-31	Belupo - Lijekovi I Kozmetika D.D.	Process for production of (s)-n-pentanoyl-n-[[2'-(
EP1714963A1 (fr) *	2005-04-19	2006-10-25	IPCA Laboratories Limited	Procédé pour la préparation du Valsartan et de ses intermédiaires
DE602006008962D1 (de) *	2005-08-22	2010-07-08	Alembic Ltd	Verfahren zur herstellung von valsartan
US7880015B2 (en) *	2006-07-03	2011-02-01	Aurobindo Pharma Ltd.	Process for the preparation of angiotensin II antagonist
CN101450917B (zh) *	2007-12-06	2012-07-11	浙江海正药业股份有限公司	缬沙坦的合成方法
EP2090567A3 (fr) *	2008-02-13	2011-06-01	Ranbaxy Laboratories Limited	Processus pour la préparation d'intermédiaires de valsartan

2009
- 2009-10-27 EP EP09174264A patent/EP2316821A1/fr not_active Ceased
2010
- 2010-10-25 BR BR112012009815A patent/BR112012009815A2/pt not_active IP Right Cessation
- 2010-10-25 AR ARP100103910A patent/AR079104A1/es not_active Application Discontinuation
- 2010-10-25 EP EP10768497A patent/EP2493848A1/fr not_active Withdrawn
- 2010-10-25 KR KR1020127010679A patent/KR20120098652A/ko not_active Withdrawn
- 2010-10-25 WO PCT/EP2010/066041 patent/WO2011051213A1/fr not_active Ceased
- 2010-10-25 CA CA2777031A patent/CA2777031A1/fr not_active Abandoned
- 2010-10-25 AU AU2010311636A patent/AU2010311636B2/en not_active Expired - Fee Related
- 2010-10-25 PE PE2012000559A patent/PE20121501A1/es not_active Application Discontinuation
- 2010-10-25 PH PH1/2012/500677A patent/PH12012500677A1/en unknown
- 2010-10-25 JP JP2012535763A patent/JP2013508436A/ja active Pending
- 2010-10-25 MX MX2012005025A patent/MX2012005025A/es not_active Application Discontinuation
- 2010-10-25 CN CN2010800487722A patent/CN102596899A/zh active Pending
- 2010-10-25 IN IN3032DEN2012 patent/IN2012DN03032A/en unknown
- 2010-10-25 US US13/504,333 patent/US20120238761A1/en not_active Abandoned
- 2010-10-25 RU RU2012121591/04A patent/RU2012121591A/ru not_active Application Discontinuation
- 2010-10-25 NZ NZ599218A patent/NZ599218A/en not_active IP Right Cessation
- 2010-10-26 TW TW099136578A patent/TW201124389A/zh unknown
2012
- 2012-04-03 TN TNP2012000154A patent/TN2012000154A1/en unknown
- 2012-04-04 ZA ZA2012/02490A patent/ZA201202490B/en unknown
- 2012-04-05 IL IL219111A patent/IL219111A0/en unknown
- 2012-04-26 EC ECSP12011833 patent/ECSP12011833A/es unknown
- 2012-04-26 CL CL2012001081A patent/CL2012001081A1/es unknown
- 2012-04-26 CO CO12068973A patent/CO6531487A2/es unknown
- 2012-04-26 MA MA34806A patent/MA33692B1/fr unknown

Also Published As

Publication number	Publication date
MX2012005025A (es)	2012-06-08
IL219111A0 (en)	2012-06-28
JP2013508436A (ja)	2013-03-07
EP2493848A1 (fr)	2012-09-05
AU2010311636A1 (en)	2012-05-03
CL2012001081A1 (es)	2013-06-14
PE20121501A1 (es)	2012-11-15
BR112012009815A2 (pt)	2016-10-18
KR20120098652A (ko)	2012-09-05
TN2012000154A1 (en)	2013-12-12
CA2777031A1 (fr)	2011-05-05
WO2011051213A1 (fr)	2011-05-05
EP2316821A1 (fr)	2011-05-04
AR079104A1 (es)	2011-12-28
ZA201202490B (en)	2012-12-27
US20120238761A1 (en)	2012-09-20
AU2010311636B2 (en)	2014-03-06
CO6531487A2 (es)	2012-09-28
RU2012121591A (ru)	2013-12-10
MA33692B1 (fr)	2012-10-01
CN102596899A (zh)	2012-07-18
ECSP12011833A (es)	2012-06-29
NZ599218A (en)	2014-02-28
PH12012500677A1 (en)	2012-10-29
TW201124389A (en)	2011-07-16

Publication	Publication Date	Title
TN2011000673A1 (en)	2013-05-24	Bace inhibitors
PH12013500554A1 (en)	2013-05-06	Process for preparing pan-cdk inhibitors of the formula (i) and intermediates in the preparation
PT2470546E (pt)	2013-10-14	Compostos de hexa-hidrooxazinopteridina para serem utilizados como inibidores de mtor
IN2012DN02642A (fr)	2015-09-11
CL2009000503A1 (es)	2010-04-09	Proceso de preparacion de compuestos derivados de acido 2-amino-5-cianobenzoico-3-sustituidos o 1h-pirazol-5-carboxamida.
WO2011022596A3 (fr)	2011-07-28	Préparation de bazédoxifène et de ses sels
JO2887B1 (en)	2015-03-15	Spiro-pyridine compounds as ORL-1 receptor antagonists
MX2011008621A (es)	2011-09-15	Proceso para la purificacion de lipopeptidos.
MX2010009003A (es)	2010-10-25	Ciclohexanodimetanamina por aminacion directa de ciclohexanodimetanol.
BR112012009823A2 (pt)	2016-10-18	poliuretano dispersível em água
EP2443457A4 (fr)	2012-10-31	Procédés, systèmes et coffrets pour détecter des interactions protéine-acide nucléique
GEP20135903B (en)	2013-08-12	Method of (1s, 2r)-milnacipran synthesis
EA201270280A1 (ru)	2013-01-30	Соединения пиримидина в качестве ингибиторов при лечении туберкулеза
MX2010000724A (es)	2010-06-02	Metodo para reducir presion intracraneal.
WO2012015999A3 (fr)	2012-08-30	Procédé de préparation de mésylate d'imatinib
TN2012000154A1 (en)	2013-12-12	Process for the manufacture of organic compounds
UA106386C2 (ru)	2014-08-26	Способ синтеза ивабрадина и его аддитивных солей с фармацевтически приемлемой кислотой
PH12012501153A1 (en)	2012-10-22	Process for synthesis of intermediates useful for making substituted indazole and azaindazole compounds
WO2011018771A3 (fr)	2011-05-12	Procédé de préparation de chlorhydrate de valganciclovir
MX2012010443A (es)	2012-12-05	Proceso para la preparacion de 1-alquiltetrazoles 5-sustituidos.
WO2012063115A3 (fr)	2012-10-26	Procédé de préparation de rosuvastatine calcique via un nouvel intermédiaire amine
MY183201A (en)	2021-02-18	Processes for the preparation of 2-(1-phenylethyl)isoindolin-1-one compounds
MX2010003056A (es)	2010-04-07	Polimorfos de valomaciclovir.
MX2011012460A (es)	2012-04-20	Proceso para la preparacion de olmesartan medoxomil.
MX337610B (es)	2016-03-10	Proceso para la preparacion de (r)-2-acetamido-n-bencil-3-metoxipr opionamida e intermediarios de la misma.