IN2012DN03807A - - Google Patents
Download PDFInfo
- Publication number
- IN2012DN03807A IN2012DN03807A IN3807DEN2012A IN2012DN03807A IN 2012DN03807 A IN2012DN03807 A IN 2012DN03807A IN 3807DEN2012 A IN3807DEN2012 A IN 3807DEN2012A IN 2012DN03807 A IN2012DN03807 A IN 2012DN03807A
- Authority
- IN
- India
- Prior art keywords
- methods
- cognitive function
- dinaline
- impairments
- metabolite
- Prior art date
Links
- 230000003920 cognitive function Effects 0.000 abstract 2
- QGMGHALXLXKCBD-UHFFFAOYSA-N 4-amino-n-(2-aminophenyl)benzamide Chemical compound C1=CC(N)=CC=C1C(=O)NC1=CC=CC=C1N QGMGHALXLXKCBD-UHFFFAOYSA-N 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25692709P | 2009-10-30 | 2009-10-30 | |
| US26546809P | 2009-12-01 | 2009-12-01 | |
| PCT/US2010/054872 WO2011053876A1 (fr) | 2009-10-30 | 2010-10-29 | Utilisation de ci-994 et de dinaline pour le traitement de troubles de la mémoire/cognition et de l'anxiété |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN03807A true IN2012DN03807A (fr) | 2015-08-28 |
Family
ID=43922604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3807DEN2012 IN2012DN03807A (fr) | 2009-10-30 | 2010-10-29 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8563615B2 (fr) |
| EP (1) | EP2493298A4 (fr) |
| JP (1) | JP2013509441A (fr) |
| CN (1) | CN102834002A (fr) |
| AU (1) | AU2010313255B2 (fr) |
| CA (1) | CA2779497A1 (fr) |
| IN (1) | IN2012DN03807A (fr) |
| NZ (1) | NZ599757A (fr) |
| WO (1) | WO2011053876A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110009475A1 (en) * | 2007-07-13 | 2011-01-13 | Massachusetts Institute Of Technology | Methods for treating stress induced emotional disorders |
| US8263547B2 (en) | 2008-05-28 | 2012-09-11 | Massachusetts Institute Of Technology | DISC-1 pathway activators in the control of neurogenesis |
| WO2011053876A1 (fr) * | 2009-10-30 | 2011-05-05 | Massachusetts Institute Of Technology | Utilisation de ci-994 et de dinaline pour le traitement de troubles de la mémoire/cognition et de l'anxiété |
| WO2012003413A1 (fr) * | 2010-06-30 | 2012-01-05 | The Broad Institute, Inc. | Nouvelles formes solides de tacédinaline |
| WO2012149540A1 (fr) | 2011-04-28 | 2012-11-01 | The Broad Institute Inc | Inhibiteurs de l'histone désacétylase |
| US8691875B2 (en) | 2011-07-01 | 2014-04-08 | Broad Institute, Inc. | Solid forms of tacedinaline |
| PT2734510T (pt) | 2011-07-22 | 2019-02-13 | Massachusetts Inst Technology | Ativadores de histona desacetilases de classe i (hdacs) e seus usos |
| EP2877444B1 (fr) * | 2012-07-27 | 2020-09-02 | The Broad Institute, Inc. | Inhibiteurs d'histone-désacétylases |
| WO2014046871A1 (fr) * | 2012-09-04 | 2014-03-27 | Massachusetts Institute Of Technology | Utilisation d'un profilage d'expression génétique comme biomarqueur pour évaluer l'efficacité d'un traitement de maladies neurodégénératives par un inhibiteur de hdac |
| US9914717B2 (en) | 2012-12-20 | 2018-03-13 | The Broad Institute, Inc. | Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors |
| CA3125731A1 (fr) | 2018-01-12 | 2019-07-18 | KDAc Therapeutics, Inc. | Combinaison d'un inhibiteur selectif de desacetylase d'histone 3 (hdac3) et d'un agent d'immunotherapie pour le traitement du cancer |
| GB202001023D0 (en) * | 2020-01-24 | 2020-03-11 | Univ Leicester | HDAC Degrader |
| CN112062826A (zh) * | 2020-06-01 | 2020-12-11 | 暨南大学 | 一种与中枢神经衰老相关的乙酰化修饰h2b蛋白标记分子及其应用 |
| WO2023034440A1 (fr) * | 2021-09-01 | 2023-03-09 | Case Western Reserve University | Traitement de maladies neurodégénératives avec des inhibiteurs de hdac |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525727A (en) | 1982-05-18 | 1996-06-11 | University Of Florida | Brain-specific drug delivery |
| US5994392A (en) | 1988-02-26 | 1999-11-30 | Neuromedica, Inc. | Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid |
| US5177064A (en) | 1990-07-13 | 1993-01-05 | University Of Florida | Targeted drug delivery via phosphonate derivatives |
| US6110697A (en) | 1995-09-20 | 2000-08-29 | Merck & Co., Inc. | Histone deacetylase as target for antiprotozoal agents |
| ATE361316T1 (de) | 1999-09-08 | 2007-05-15 | Sloan Kettering Inst Cancer | Kristallstruktur einer deacetylase und deren inhibitoren |
| US6713454B1 (en) | 1999-09-13 | 2004-03-30 | Nobex Corporation | Prodrugs of etoposide and etoposide analogs |
| KR20100035666A (ko) | 1999-11-23 | 2010-04-05 | 메틸진 인크. | 히스톤 디아세틸라제의 억제제 |
| JP2001149081A (ja) | 1999-11-29 | 2001-06-05 | Cyclex Co Ltd | 脱アセチル化酵素の活性測定方法、並びにこれら酵素の阻害剤もしくは促進剤のスクリーニング方法 |
| EP2292593A3 (fr) | 2000-09-29 | 2011-05-25 | TopoTarget UK Limited | Composés d'acide carbamique comportant une liaison de sulfamide en tant qu'inhibiteurs HDAC |
| US20060148743A1 (en) | 2001-05-18 | 2006-07-06 | Vasant Jadhav | RNA interference mediated inhibition of histone deacetylase (HDAC) gene expression using short interfering nucleic acid (siNA) |
| WO2002102323A2 (fr) | 2001-06-14 | 2002-12-27 | Bristol-Myers Squibb Company | Nouvelles histones deacetylases humaines |
| CA2465978C (fr) | 2001-09-14 | 2015-04-07 | Soon Hyung Woo | Inhibiteurs de l'histone-deacetylase |
| EP1443928B1 (fr) | 2001-10-16 | 2011-07-27 | Sloan-Kettering Institute For Cancer Research | Traitement des maladies neurodegeneratives et du cancer du cerveau |
| AU2002361022A1 (en) | 2001-12-07 | 2003-06-17 | Novartis Ag | Use of alpha-tubulin acetylation levels as a biomarker for protein deacetylase inhibitors |
| JP2005517007A (ja) | 2002-02-07 | 2005-06-09 | アクシス・ファーマスーティカルズ | ヒストンデアセチラーゼ阻害剤としての新規二環式ヒドロキサメート |
| WO2003066885A2 (fr) | 2002-02-08 | 2003-08-14 | Novartis Ag | Procede de criblage de composes presentant une activite inhibitrice de hdac |
| US20050288227A1 (en) | 2002-02-15 | 2005-12-29 | Marks Paul A | Use of thioredoxin measurements for diagnostics and treatments |
| US20030235588A1 (en) * | 2002-02-15 | 2003-12-25 | Richon Victoria M. | Method of treating TRX mediated diseases |
| US7456219B2 (en) | 2002-03-04 | 2008-11-25 | Merck Hdac Research, Llc | Polymorphs of suberoylanilide hydroxamic acid |
| WO2003083067A2 (fr) | 2002-03-28 | 2003-10-09 | Brigham And Women's Hospital, Inc. | Inhibiteurs d'histone deacetylase permettant de traiter la sclerose en plaques, la sclerose laterale amyotrophique et la maladie d'alzheimer |
| US20030224473A1 (en) | 2002-05-23 | 2003-12-04 | Mccafferty Dewey G. | Methods for screening for histone deacetylase activity and for identifying histone deacetylase inhibitors |
| EP1551795A1 (fr) | 2002-10-17 | 2005-07-13 | Methylgene, Inc. | Inhibiteurs de l'histone deacetylase |
| TW200424174A (en) | 2003-02-06 | 2004-11-16 | Hoffmann La Roche | New TP diamide |
| US20050037992A1 (en) | 2003-07-22 | 2005-02-17 | John Lyons | Composition and method for treating neurological disorders |
| AU2004276337B2 (en) | 2003-09-24 | 2009-11-12 | Methylgene Inc. | Inhibitors of histone deacetylase |
| US20050227929A1 (en) * | 2003-11-13 | 2005-10-13 | Masferrer Jaime L | Combination therapy comprising a Cox-2 inhibitor and an antineoplastic agent |
| AU2005225471B2 (en) | 2004-03-26 | 2011-05-12 | Methylgene Inc. | Inhibitors of histone deacetylase |
| JP2007533745A (ja) * | 2004-04-20 | 2007-11-22 | アールエヌディー・ファーマシューティカルズ | 脂溶性のシリコン置換シクロオキシゲナーゼ−２選択的非ステロイド性抗炎症薬及び誘導体の医薬組成物及び使用方法 |
| EP1591109B1 (fr) * | 2004-04-30 | 2008-07-02 | TopoTarget Germany AG | Formulation à libération biphasique comprenant un inhibiteur d'histone déacétylase |
| US20060008517A1 (en) | 2004-07-09 | 2006-01-12 | Lynch Marina A | Treatment of age-related memory impairment |
| US20060018921A1 (en) | 2004-07-16 | 2006-01-26 | Baylor College Of Medicine | Histone deacetylase inhibitors and cognitive applications |
| CA2587013A1 (fr) | 2004-11-08 | 2006-05-18 | Errant Gene Therapeutics, Llc | Inhibiteurs d'histone deacetylase |
| JP2008540574A (ja) | 2005-05-11 | 2008-11-20 | タケダ サン ディエゴ インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
| US20070015183A1 (en) | 2005-06-03 | 2007-01-18 | The General Hospital Corporation | Biomarkers for huntington's disease |
| CA2615105A1 (fr) | 2005-07-14 | 2007-01-25 | Takeda San Diego, Inc. | Inhibiteurs de l'histone deacetylase |
| CA2621560A1 (fr) | 2005-09-07 | 2007-03-15 | Braincells, Inc. | Modulation de la neurogenese par inhibition de la hdac |
| WO2007049262A1 (fr) * | 2005-10-27 | 2007-05-03 | Berand Limited | Procedes et compositions pour favoriser la croissance neuronale et le traitement de l'asociabilite et des troubles affectifs |
| JP2009514859A (ja) | 2005-11-03 | 2009-04-09 | メルク エンド カムパニー インコーポレーテッド | 置換ニコチンアミド化合物 |
| WO2007056435A2 (fr) * | 2005-11-08 | 2007-05-18 | The General Hospital Corporation | Maladies mediees par la dynamine et procedes et produits associes |
| US8168658B2 (en) | 2006-02-28 | 2012-05-01 | Merck Sharp & Dohme Corp. | Inhibitors of histone deacetylase |
| CA2648804C (fr) | 2006-04-07 | 2014-05-27 | Methylgene Inc. | Derives de benzamide utilises en tant qu'inhibiteurs de l'histone desacetylase |
| WO2007127137A2 (fr) | 2006-04-26 | 2007-11-08 | Merck & Co., Inc. | Composés de l'aniline disubstitués |
| CA2651681A1 (fr) | 2006-05-18 | 2007-11-29 | Merck & Co., Inc. | Composes spirocycliques fusionnes a aryle |
| US20100112600A1 (en) | 2006-07-13 | 2010-05-06 | Azard Bonni | Methods and compositions for modulating synapse formation |
| US8088951B2 (en) | 2006-11-30 | 2012-01-03 | Massachusetts Institute Of Technology | Epigenetic mechanisms re-establish access to long-term memory after neuronal loss |
| US8030344B2 (en) | 2007-03-13 | 2011-10-04 | Methylgene Inc. | Inhibitors of histone deacetylase |
| US20110009475A1 (en) | 2007-07-13 | 2011-01-13 | Massachusetts Institute Of Technology | Methods for treating stress induced emotional disorders |
| US8263547B2 (en) | 2008-05-28 | 2012-09-11 | Massachusetts Institute Of Technology | DISC-1 pathway activators in the control of neurogenesis |
| AU2009274571A1 (en) | 2008-07-23 | 2010-01-28 | Massachusetts Institute Of Technology | Activation of histone deacetylase 1 (HDAC1) protects against DNA damage and increases neuronal survival |
| JP2012510512A (ja) | 2008-12-03 | 2012-05-10 | マサチューセッツ インスティテュート オブ テクノロジー | 記憶を推進するためのｈｄａｃ２の阻害 |
| WO2010098888A1 (fr) | 2009-02-27 | 2010-09-02 | Massachusetts Institute Of Technology | Utilisations de produits chimiques pour moduler la signalisation par gsk–3 pour le traitement d'un trouble bipolaire et autres troubles cérébraux |
| WO2011053876A1 (fr) | 2009-10-30 | 2011-05-05 | Massachusetts Institute Of Technology | Utilisation de ci-994 et de dinaline pour le traitement de troubles de la mémoire/cognition et de l'anxiété |
| PT2734510T (pt) | 2011-07-22 | 2019-02-13 | Massachusetts Inst Technology | Ativadores de histona desacetilases de classe i (hdacs) e seus usos |
-
2010
- 2010-10-29 WO PCT/US2010/054872 patent/WO2011053876A1/fr not_active Ceased
- 2010-10-29 CN CN201080060203XA patent/CN102834002A/zh active Pending
- 2010-10-29 CA CA2779497A patent/CA2779497A1/fr not_active Abandoned
- 2010-10-29 AU AU2010313255A patent/AU2010313255B2/en not_active Ceased
- 2010-10-29 IN IN3807DEN2012 patent/IN2012DN03807A/en unknown
- 2010-10-29 EP EP10827583.5A patent/EP2493298A4/fr not_active Withdrawn
- 2010-10-29 NZ NZ599757A patent/NZ599757A/en not_active IP Right Cessation
- 2010-10-29 JP JP2012537154A patent/JP2013509441A/ja active Pending
- 2010-11-01 US US12/917,402 patent/US8563615B2/en not_active Expired - Fee Related
-
2012
- 2012-08-27 US US13/595,048 patent/US8841346B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN102834002A (zh) | 2012-12-19 |
| US20110224303A1 (en) | 2011-09-15 |
| WO2011053876A1 (fr) | 2011-05-05 |
| EP2493298A1 (fr) | 2012-09-05 |
| US8841346B2 (en) | 2014-09-23 |
| AU2010313255A1 (en) | 2012-05-31 |
| AU2010313255B2 (en) | 2015-04-30 |
| CA2779497A1 (fr) | 2011-05-05 |
| NZ599757A (en) | 2014-08-29 |
| US20120322879A1 (en) | 2012-12-20 |
| JP2013509441A (ja) | 2013-03-14 |
| US8563615B2 (en) | 2013-10-22 |
| EP2493298A4 (fr) | 2013-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2011007930A (es) | Conjugados de insulina cristalina. | |
| IN2014CN02616A (fr) | ||
| WO2013072932A3 (fr) | Compositions de soin oral | |
| MX356210B (es) | Formulaciones de polimero acrilico. | |
| AP2012006189A0 (en) | 2'-fluoro substituted carbanucleoside analogs for antiviral treatment. | |
| WO2011057262A3 (fr) | Traitement des infections par des antagonistes du récepteur tp | |
| IL232914A0 (en) | New Azetidine histories, pharmaceutical preparations and their uses | |
| ZA201301463B (en) | Pharmaceutical compositions for calonolides,their derivatives and analogues,and process for producing the same | |
| UA86731C2 (ru) | Делимая галеновая форма модифицированного высвобождения активного ингредиента | |
| TW200942530A (en) | Pyridine compounds | |
| WO2011009938A3 (fr) | Stambomycine et dérivés, leur production et leur utilisation comme médicaments | |
| MY155330A (en) | Methods for salt production | |
| ZA201108292B (en) | New compounds,pharmaceutical composition and methods relating thereto | |
| WO2012016683A3 (fr) | Forme galénique orale de prégabaline | |
| GB2482817A (en) | Novel use | |
| EP2794806A4 (fr) | Compositions de type azéotropique comprenant du cis-1-chloro-3,3,3-trifluoropropène | |
| WO2009011901A3 (fr) | Procédés pour favoriser la veille | |
| IN2014MN01382A (fr) | ||
| MX2012010317A (es) | ß-HIDROXIALQUILAMIDAS, METODO PARA SU PRODUCCION Y SU USO. | |
| MX349563B (es) | Formulacion farmaceutica de fenofibrato nanonizado. | |
| UA96476C2 (ru) | Фармацевтические композиции, которые содержат ирбесартан | |
| WO2012082942A3 (fr) | Analogues de neuropeptides, compositions et procédés pour le traitement de la douleur | |
| WO2012174243A8 (fr) | D-sérine dans le traitement des troubles du système visuel | |
| WO2010083240A9 (fr) | Procédés pour le traitement de troubles inflammatoires au moyen de composés de la 2,4-pyrimidine diamine | |
| EP2387565A4 (fr) | Composés de la 2,4-pyrimidine diamine pour le traitement de troubles inflammatoires |