IN2012DN04908A - - Google Patents

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Publication number
IN2012DN04908A
IN2012DN04908A IN4908DEN2012A IN2012DN04908A IN 2012DN04908 A IN2012DN04908 A IN 2012DN04908A IN 4908DEN2012 A IN4908DEN2012 A IN 4908DEN2012A IN 2012DN04908 A IN2012DN04908 A IN 2012DN04908A
Authority
IN
India
Prior art keywords
antibody
disclosed
antibodies
expressing cells
drug conjugates
Prior art date
Application number
Other languages
English (en)
Inventor
Michel Pierres
Eric Vivier
Myriam Baratin
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43827827&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN04908(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Publication of IN2012DN04908A publication Critical patent/IN2012DN04908A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN4908DEN2012 2009-12-09 2010-12-08 IN2012DN04908A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28501809P 2009-12-09 2009-12-09
PCT/IB2010/003411 WO2011070443A1 (fr) 2009-12-09 2010-12-08 Anticorps monoclonaux qui se lient à b7h6 et leurs utilisations

Publications (1)

Publication Number Publication Date
IN2012DN04908A true IN2012DN04908A (fr) 2015-09-25

Family

ID=43827827

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4908DEN2012 IN2012DN04908A (fr) 2009-12-09 2010-12-08

Country Status (18)

Country Link
US (2) US8822652B2 (fr)
EP (1) EP2510011B2 (fr)
JP (2) JP2013513380A (fr)
CN (2) CN102741290B (fr)
BR (1) BR112012013975B8 (fr)
CA (1) CA2783740C (fr)
DK (1) DK2510011T3 (fr)
EA (1) EA024629B1 (fr)
ES (1) ES2523472T3 (fr)
HR (1) HRP20141170T1 (fr)
IN (1) IN2012DN04908A (fr)
MX (1) MX2012006443A (fr)
PL (1) PL2510011T3 (fr)
PT (1) PT2510011E (fr)
RS (1) RS53667B1 (fr)
SI (1) SI2510011T1 (fr)
SM (1) SMT201400184B (fr)
WO (1) WO2011070443A1 (fr)

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US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
US12492376B2 (en) 2009-10-29 2025-12-09 The Trustees Of Dartmouth College T-cell receptor-deficient T cell compositions
IN2012DN04908A (fr) 2009-12-09 2015-09-25 Inst Nat Sante Rech Med
US9833476B2 (en) 2011-08-31 2017-12-05 The Trustees Of Dartmouth College NKP30 receptor targeted therapeutics
WO2013037727A1 (fr) * 2011-09-13 2013-03-21 Deutsches Krebsforschungszentrum Anticorps monoclonal thérapeutiquement actif contre le polypeptide b7-h6
ES2719495T5 (en) * 2012-05-07 2025-09-10 Dartmouth College Anti-b7-h6 antibody, fusion proteins, and methods of using the same
WO2014044799A1 (fr) * 2012-09-21 2014-03-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Méthodes et trousses pour le diagnostic d'états inflammatoires impliquant la détection, l'identification ou l'estimation de polypeptides b7-h6 solubles
EP2711707A1 (fr) 2012-09-21 2014-03-26 Institut Gustave Roussy Procédés et kits pour prédire la sensibilité d'un sujet à une chimiothérapie
CN109310764B (zh) * 2016-04-15 2022-01-14 达特茅斯大学理事会 高亲和力b7-h6抗体和抗体片段
EP3469001A4 (fr) * 2016-06-09 2020-05-06 Seattle Genetics, Inc. Combinaisons de conjugués anticorps-médicament à base de pbd avec des d'inhibiteurs de flt3
WO2019099687A1 (fr) * 2017-11-16 2019-05-23 Antigenesis Llc Systèmes et procédés de mort cellulaire immunogène induite par lysosome
WO2019139987A1 (fr) 2018-01-09 2019-07-18 Elstar Therapeutics, Inc. Constructions de liaison à la calréticuline et lymphocytes t modifiés pour le traitement de maladies
US12152073B2 (en) 2018-03-14 2024-11-26 Marengo Therapeutics, Inc. Multifunctional molecules that bind to calreticulin and uses thereof
WO2020010250A2 (fr) 2018-07-03 2020-01-09 Elstar Therapeutics, Inc. Molécules d'anticorps anti-tcr et leurs utilisations
GB2597851B (en) 2019-02-21 2024-05-29 Marengo Therapeutics Inc Antibody molecules that bind to NKP30 and uses thereof
AU2020226893B2 (en) 2019-02-21 2025-02-27 Marengo Therapeutics, Inc. Multifunctional molecules that bind to T cell related cancer cells and uses thereof
AU2020416273A1 (en) 2020-01-03 2022-07-28 Marengo Therapeutics, Inc. Anti-TCR antibody molecules and uses thereof
IL294714A (en) * 2020-01-17 2022-09-01 Beigene Ltd Anti-nkp30 antibodies and methods of use
JP2024511465A (ja) 2021-03-26 2024-03-13 イナート・ファルマ・ソシエテ・アノニム Ｎｋ細胞エンゲージングのためにサイトカインに融合したｎｋｐ４６結合性部位、がん抗原結合性部位を含む多特異性タンパク質
MX2023014647A (es) 2021-06-09 2024-01-31 Innate Pharma Proteinas de union a nkp46 multiespecificas.
WO2022258691A1 (fr) 2021-06-09 2022-12-15 Innate Pharma Protéines multispécifiques se liant à nkg2d, récepteur de cytokine, antigène tumoral et cd16a
WO2022258678A1 (fr) 2021-06-09 2022-12-15 Innate Pharma Protéines multispécifiques se liant à nkp30, un récepteur de cytokine, un antigène tumoral et cd16a
CN114395047B (zh) * 2021-12-07 2023-11-07 合肥天港免疫药物有限公司 双特异性抗体及其应用
CN114395043B (zh) * 2021-12-07 2023-07-11 合肥天港免疫药物有限公司 Ncr3lg1抗体及其应用
CN114395044B (zh) * 2021-12-07 2023-12-29 合肥天港免疫药物有限公司 重组抗体及其应用
CN114395045B (zh) * 2021-12-07 2023-06-09 合肥天港免疫药物有限公司 B7h6抗体及其应用
CN114634574B (zh) * 2022-04-18 2022-12-20 先进生物(苏州)有限公司 抗B7H6的scFv抗体、其编码基因及其应用
KR20240003756A (ko) * 2022-06-29 2024-01-09 고려대학교 산학협력단 NKp30 결합력이 향상된 B7-H6 변이체
WO2024104777A1 (fr) * 2022-11-16 2024-05-23 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Inhibiteurs d'interaction de cellules nk-cellules destinés à être utilisés dans le traitement de maladies
WO2024208818A1 (fr) 2023-04-04 2024-10-10 Innate Pharma Récepteur antigénique chimérique modulaire
CN121628833B (zh) * 2026-02-03 2026-05-08 浙江省中医院、浙江中医药大学附属第一医院（浙江省东方医院） 人源壶腹癌细胞系dpc-x5及其应用

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Also Published As

Publication number Publication date
EP2510011A1 (fr) 2012-10-17
CA2783740A1 (fr) 2011-06-16
SMT201400184B (it) 2015-01-15
CN104926942A (zh) 2015-09-23
PT2510011E (pt) 2014-12-12
US20150056214A1 (en) 2015-02-26
PL2510011T3 (pl) 2015-02-27
BR112012013975B8 (pt) 2021-05-25
US8822652B2 (en) 2014-09-02
WO2011070443A1 (fr) 2011-06-16
JP2017031147A (ja) 2017-02-09
EA201270654A1 (ru) 2013-02-28
HRP20141170T1 (hr) 2015-01-30
EA024629B1 (ru) 2016-10-31
MX2012006443A (es) 2012-06-28
EP2510011B1 (fr) 2014-09-17
RS53667B1 (sr) 2015-04-30
BR112012013975B1 (pt) 2021-01-12
ES2523472T3 (es) 2014-11-26
CN102741290B (zh) 2015-04-22
DK2510011T3 (en) 2014-12-01
SI2510011T1 (sl) 2014-12-31
CN104926942B (zh) 2018-09-14
US20130004432A1 (en) 2013-01-03
BR112012013975A2 (pt) 2017-01-10
JP2013513380A (ja) 2013-04-22
US9663577B2 (en) 2017-05-30
CN102741290A (zh) 2012-10-17
EP2510011B2 (fr) 2021-03-31
JP6212181B2 (ja) 2017-10-11
CA2783740C (fr) 2020-03-10

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