IN2014CN04039A - - Google Patents

Download PDF

Info

Publication number
IN2014CN04039A
IN2014CN04039A IN4039CHN2014A IN2014CN04039A IN 2014CN04039 A IN2014CN04039 A IN 2014CN04039A IN 4039CHN2014 A IN4039CHN2014 A IN 4039CHN2014A IN 2014CN04039 A IN2014CN04039 A IN 2014CN04039A
Authority
IN
India
Prior art keywords
secretory production
heterologous protein
protein
activity
produce
Prior art date
Application number
Other languages
English (en)
Inventor
Yoshihiko Matsuda
Hiroshi Itaya
Yoshimi Kikuchi
Haruki Beppu
Jurgis Antanas Vladovich Jomantas
Ekaterina Aleksandrovna Kutukova
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2011144497/10A external-priority patent/RU2011144497A/ru
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of IN2014CN04039A publication Critical patent/IN2014CN04039A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
IN4039CHN2014 2011-11-02 2012-11-01 IN2014CN04039A (2)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2011144497/10A RU2011144497A (ru) 2011-11-02 2011-11-02 Способ секреторного получения белка
JP2011240745 2011-11-02
PCT/JP2012/078906 WO2013065869A1 (en) 2011-11-02 2012-11-01 Method for secretory production of protein

Publications (1)

Publication Number Publication Date
IN2014CN04039A true IN2014CN04039A (2) 2015-10-23

Family

ID=47222244

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4039CHN2014 IN2014CN04039A (2) 2011-11-02 2012-11-01

Country Status (8)

Country Link
US (1) US9187554B2 (2)
EP (1) EP2748340B1 (2)
JP (1) JP6020581B2 (2)
KR (1) KR101653555B1 (2)
CN (1) CN103946371B (2)
AU (1) AU2012333451B2 (2)
IN (1) IN2014CN04039A (2)
WO (1) WO2013065869A1 (2)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014CN04002A (2) 2011-11-02 2015-10-23 Ajinomoto Kk
EP2748340B1 (en) 2011-11-02 2016-06-01 Ajinomoto Co., Inc. Method for secretory production of proteins
RU2013119826A (ru) 2013-04-29 2014-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Коринеформная бактерия и способ получения гетерологичных гибридных белков
WO2015060391A1 (ja) 2013-10-23 2015-04-30 味の素株式会社 目的物質の製造法
SG11201609108TA (en) * 2014-05-02 2016-12-29 Univ Shinshu Antibody gene expression-secretion system
US10519248B2 (en) * 2014-07-25 2019-12-31 Memorial Sloan Kettering Cancer Center Bispecific HER2 and CD3 binding molecules
CN107532163B (zh) 2015-04-24 2026-04-17 味之素株式会社 蛋白质的分泌生产方法
KR102335301B1 (ko) 2016-10-21 2021-12-06 아지노모토 가부시키가이샤 단백질의 분비 생산법
CN109937258B (zh) * 2016-10-21 2023-06-23 味之素株式会社 蛋白质的分泌产生方法
CN110494567B (zh) 2017-03-28 2024-07-12 味之素株式会社 生产rna的方法
EP3756466A4 (en) 2018-02-20 2021-11-24 Ajinomoto Co., Inc. METHOD FOR INDUCING RNA SILENCING
EP3783106A4 (en) 2018-04-20 2022-01-05 Ajinomoto Co., Inc. PROCESS FOR THE SECRETION OF A PROTEIN
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
WO2020085511A1 (ja) 2018-10-25 2020-04-30 味の素株式会社 タンパク質の分泌生産法
CN111909879B (zh) * 2020-08-24 2023-04-28 江南大学 一种高效表达外源蛋白的谷氨酸棒杆菌诱变菌株及应用
US12180521B2 (en) 2021-02-19 2024-12-31 Theripion, Inc. Paraoxonase fusion polypeptides and related compositions and methods
WO2023282315A1 (ja) 2021-07-07 2023-01-12 味の素株式会社 非天然アミノ酸含有タンパク質の分泌生産法
WO2023200008A1 (ja) 2022-04-15 2023-10-19 味の素株式会社 培養肉の製造方法
JPWO2024172163A1 (2) 2023-02-16 2024-08-22

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57134500A (en) 1981-02-12 1982-08-19 Kyowa Hakko Kogyo Co Ltd Plasmid pcg1
JPS57183799A (en) 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid
JPS5835197A (ja) 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドpcg2
JPS58192900A (ja) 1982-05-04 1983-11-10 Ajinomoto Co Inc 複合プラスミド
US4965197A (en) 1987-06-12 1990-10-23 Massachusetts Institute Of Technology Coryneform expression and secretion system
JPH01191686A (ja) 1988-01-26 1989-08-01 Mitsubishi Petrochem Co Ltd 複合プラスミド
JP2678995B2 (ja) 1988-09-08 1997-11-19 三菱化学株式会社 トリプトフアンシンターゼの製造法
US5185262A (en) 1988-07-27 1993-02-09 Mitsubishi Petrochemical Co., Ltd. DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism
JP2973446B2 (ja) 1990-01-11 1999-11-08 三菱化学株式会社 新規プラスミドベクター
JPH07108228B2 (ja) 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド
JP2925776B2 (ja) 1991-04-22 1999-07-28 三洋電機株式会社 吸収式冷凍機
WO1993003158A1 (fr) 1991-07-30 1993-02-18 Orsan Systeme d'expression et de secretion de proteines utilisables en particulier chez les corynebacteries
DE69535037T2 (de) 1994-08-26 2006-12-07 Novozymes A/S Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung
WO1996022366A1 (en) 1995-01-19 1996-07-25 Novo Nordisk A/S Transglutaminases from oomycetes
JPH0970291A (ja) 1995-06-30 1997-03-18 Ajinomoto Co Inc 人工トランスポゾンを用いた遺伝子増幅方法
JP4035855B2 (ja) 1996-06-05 2008-01-23 味の素株式会社 L−リジンの製造法
JP3711658B2 (ja) 1996-10-07 2005-11-02 味の素株式会社 コリネバクテリウム・アンモニアゲネス由来の新規な細胞表層蛋白質
JP4168463B2 (ja) 1996-12-05 2008-10-22 味の素株式会社 L−リジンの製造法
JPH11169182A (ja) 1997-12-10 1999-06-29 Mitsubishi Chemical Corp コリネ型細菌内で蛋白質を効率よく培地中へ分泌させる変異型分泌装置遺伝子
CN101200742A (zh) * 1998-03-06 2008-06-18 味之素株式会社 编码青霉素结合蛋白的基因和生产l-谷氨酸的方法
JP2000262288A (ja) 1999-03-16 2000-09-26 Ajinomoto Co Inc コリネ型細菌の温度感受性プラスミド
US20050244935A1 (en) 1999-06-25 2005-11-03 Basf Ag Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
KR100815041B1 (ko) 1999-08-02 2008-03-18 아처 다니엘 미드랜드 캄파니 아미노산 생산의 대사 공학
WO2001023591A1 (en) 1999-09-30 2001-04-05 Ajinomoto Co., Inc. Process for producing transglutaminase
JP4207426B2 (ja) 2000-01-21 2009-01-14 味の素株式会社 L−リジンの製造法
EP1375664B1 (en) 2001-03-30 2009-11-04 Ajinomoto Co., Inc. Method for the secretion and production of protein
EP1548116A4 (en) * 2002-09-30 2006-04-05 Ajinomoto Kk PROCESS FOR PRODUCING A PROTEIN MARKED BY A STABLE ISOTOPE
WO2004078973A1 (ja) 2003-03-07 2004-09-16 Ajinomoto Co. Inc. 微生物トランスグルタミナーゼの製造法
US7807176B2 (en) 2004-03-19 2010-10-05 Genomidea, Inc. Polypeptide promoting vascular endothelial cell growth
BRPI0509056A (pt) 2004-03-31 2007-08-21 Ajinomoto Kk bactéria pertencendo ao gênero bacillus ou ao gênero escherichia, e, métodos para produzir um nucleosìdeo de purina, para produzir um nucleotìdeo de purina e para produzir ácido 5'-guanìlico
WO2005103278A1 (ja) 2004-04-20 2005-11-03 Ajinomoto Co., Inc. タンパク質の製造法
EP1760143B1 (en) 2004-05-20 2012-05-16 Ajinomoto Co., Inc. Succinic acid-producing bacterium and process for producing succinic acid
JP4595506B2 (ja) 2004-11-25 2010-12-08 味の素株式会社 L−アミノ酸生産菌及びl−アミノ酸の製造方法
CA2598792A1 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
US7723097B2 (en) 2005-03-11 2010-05-25 Archer-Daniels-Midland Company Escherichia coli strains that over-produce L-threonine and processes for their production
RU2365622C2 (ru) 2006-12-22 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПРОДУКЦИИ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ МЕТОДОМ ФЕРМЕНТАЦИИ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Escherichia ИЛИ Bacillus
CN102089437B (zh) 2008-07-09 2014-11-05 味之素株式会社 生产氨基羟基苯甲酸盐类化合物的方法
IN2014CN04002A (2) 2011-11-02 2015-10-23 Ajinomoto Kk
EP2748340B1 (en) 2011-11-02 2016-06-01 Ajinomoto Co., Inc. Method for secretory production of proteins

Also Published As

Publication number Publication date
JP6020581B2 (ja) 2016-11-02
CN103946371B (zh) 2016-07-06
AU2012333451A1 (en) 2014-04-03
KR20140088215A (ko) 2014-07-09
KR101653555B1 (ko) 2016-09-02
JP2014532424A (ja) 2014-12-08
EP2748340B1 (en) 2016-06-01
EP2748340A1 (en) 2014-07-02
US20140255996A1 (en) 2014-09-11
RU2014122201A (ru) 2015-12-10
WO2013065869A1 (en) 2013-05-10
CN103946371A (zh) 2014-07-23
US9187554B2 (en) 2015-11-17
AU2012333451B2 (en) 2015-05-21

Similar Documents

Publication Publication Date Title
IN2014CN04039A (2)
IN2014CN04002A (2)
WO2012129548A3 (en) In situ expression of lipase for enzymatic production of alcohol esters during fermentation
WO2013003744A3 (en) Bioconversion process for producing nylon-7, nylon-7,7 and polyesters
MX2014012810A (es) Sistemas de celulas y metodos para mejorar la sintesis de acidos grasos mediante la expresion de deshidrogenasas.
MY165893A (en) Biological methods for preparing a fatty dicarboxylic acid
IN2014CN03887A (2)
MX355790B (es) Microorganismo recombinante para la produccion fermentativa de metionina.
MX349658B (es) Metodo para la diferenciacion de las celulas madre pluripotentes en celulas de lecho vascular.
IN2015DN02630A (2)
WO2013096898A3 (en) Bioconversion process for producing nylon-7, nylon-7,7 and polyesters
PL2796555T3 (pl) Sposób wytwarzania L-lizyny z użyciem mikroorganizmu mającego zdolność wytwarzania L-lizyny
PL2917359T3 (pl) Sposób enzymatycznej hydrolizy materiału lignocelulozowego z zastosowaniem tlenu
MY161726A (en) Biological methods for preparing adipic acid
EP2686436A4 (en) PROCESS FOR INTRODUCING CELLULASE CYCLES IN A LIGNOCELLULOSE ROHSTOF FAUFSCHLÄMMUNG
IN2014CN03196A (2)
AP3616A (en) Methods for improvement of enzymatic hydrolysis of lignocellulosic material
WO2012126013A3 (en) Method for making pluripotent stem cells
EP4458858A3 (en) Method for the production of immunoglobulin single variable domains
WO2015004403A3 (fr) Procede de culture cellulaire decouple
IN2014DN09217A (2)
MY180645A (en) Microbial production of fatty amines
WO2012141542A3 (ko) 미생물 발효를 통해 제조된 생성물을 흡착제를 이용하여 분리 정제하는 장치 및 방법
WO2014049382A3 (en) Ethylenediamine fermentative production by a recombinant microorganism
DK201370720A (en) Mutant microorganism belonging to the genus trichoderma and method for producing protein using the same