IN2014DN08135A - - Google Patents

Info

Publication number
IN2014DN08135A
IN2014DN08135A IN8135DEN2014A IN2014DN08135A IN 2014DN08135 A IN2014DN08135 A IN 2014DN08135A IN 8135DEN2014 A IN8135DEN2014 A IN 8135DEN2014A IN 2014DN08135 A IN2014DN08135 A IN 2014DN08135A
Authority
IN
India
Prior art keywords
reaction sites
chip
biological reactions
nanoliter
substrate
Prior art date
Application number
Other languages
English (en)
Inventor
Michael C Pallas
James Nurse
Gary Lim
Theodore Straub
Eliodor Ghenciu
Evan Foster
Jorge Fonseca
Kevin Maher
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of IN2014DN08135A publication Critical patent/IN2014DN08135A/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50857—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates using arrays or bundles of open capillaries for holding samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50851—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/20—Exposure; Apparatus therefor
    • G03F7/2002—Exposure; Apparatus therefor with visible light or UV light, through an original having an opaque pattern on a transparent support, e.g. film printing, projection printing; by reflection of visible or UV light from an original such as a printed image
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/142—Preventing evaporation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0896—Nanoscaled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
IN8135DEN2014 2012-03-16 2013-03-15 IN2014DN08135A (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201261612087P 2012-03-16 2012-03-16
US201261612005P 2012-03-16 2012-03-16
US201261612008P 2012-03-16 2012-03-16
US201261659029P 2012-06-13 2012-06-13
US201261723710P 2012-11-07 2012-11-07
US201261723759P 2012-11-07 2012-11-07
US201261723658P 2012-11-07 2012-11-07
US201261723738P 2012-11-07 2012-11-07
US201361774499P 2013-03-07 2013-03-07
PCT/US2013/032420 WO2013138767A1 (en) 2012-03-16 2013-03-15 Systems and methods for biological analysis

Publications (1)

Publication Number Publication Date
IN2014DN08135A true IN2014DN08135A (da) 2015-05-01

Family

ID=48014371

Family Applications (1)

Application Number Title Priority Date Filing Date
IN8135DEN2014 IN2014DN08135A (da) 2012-03-16 2013-03-15

Country Status (10)

Country Link
US (4) US20150044686A1 (da)
EP (2) EP2825310A2 (da)
JP (2) JP2015511015A (da)
KR (2) KR20140140080A (da)
CN (2) CN104302400B (da)
AU (1) AU2013231910A1 (da)
IN (1) IN2014DN08135A (da)
RU (2) RU2014140837A (da)
SG (2) SG11201406039WA (da)
WO (2) WO2013138706A2 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012100824A1 (de) * 2012-02-01 2013-09-05 Albert-Ludwigs-Universität Freiburg Gemultiplexte Digital PCR
CA2915475A1 (en) 2013-05-24 2014-11-27 Life Technologies Corporation Case and case holder for biological samples and corresponding method of use
EP3142790B8 (en) * 2014-05-14 2019-04-24 Hooke Bio Limited Method for handling fluid in a microfluidic device with channel plates
JP6800864B2 (ja) 2015-02-06 2020-12-16 ライフ テクノロジーズ コーポレーション 生物学的分析のためのシステムおよび方法
EP3719481B1 (en) * 2015-02-06 2023-03-29 Life Technologies Corporation An optical instrument for biological analysis
JP6661947B2 (ja) * 2015-10-01 2020-03-11 凸版印刷株式会社 蛍光画像撮影装置及び蛍光画像撮影方法
CN105543064B (zh) * 2015-12-29 2018-04-17 西安交通大学 一种数字pcr芯片及其使用方法
CN109313396B (zh) * 2016-05-18 2022-11-22 Illumina公司 使用图案化疏水性表面进行的自组装图案化
WO2018085835A1 (en) 2016-11-07 2018-05-11 Battelle Memorial Institute Nanoscale biochemical sample preparation and analysis
US11719702B2 (en) 2016-11-07 2023-08-08 Battelle Memorial Institute Methods and systems of proteome analysis and imaging
US11085039B2 (en) 2016-12-12 2021-08-10 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
EP3551745A4 (en) 2016-12-12 2020-07-15 Xcella Biosciences, Inc. SCREENING METHODS AND SYSTEMS USING MICROCAPILLARY NETWORKS
CN110382439B (zh) 2016-12-30 2026-07-21 埃克切拉生物科学公司 多级样品回收系统
CN107254511A (zh) * 2017-04-27 2017-10-17 臻准生物科技(上海)有限公司 一种数字pcr芯片信号读取方法
CN110878250A (zh) * 2018-09-05 2020-03-13 上海新微技术研发中心有限公司 基于通孔结构和微流控的dPCR原位芯片及制作方法
DK3890876T3 (da) 2018-12-06 2024-07-22 Xcella Biosciences Inc Lateral påfyldning af mikrokapillære arrays
CN111349555B (zh) * 2018-12-21 2023-07-18 成都万众壹芯生物科技有限公司 一种基于微孔阵列芯片的数字pcr扩增装置及其使用方法
JP7347931B2 (ja) * 2018-12-26 2023-09-20 スリーエム イノベイティブ プロパティズ カンパニー マイクロ流体デバイス用フィルム、マイクロ流体デバイス及びその製造方法
US12140542B2 (en) * 2019-03-28 2024-11-12 National University Corporation Ehime University Optical analysis chip
CN112239719A (zh) * 2019-07-19 2021-01-19 成都万众壹芯生物科技有限公司 基于微孔阵列芯片的数字pcr扩增装置和利用其进行扩增的方法
CA3156776A1 (en) 2019-11-08 2021-05-14 xCella Biosciences, Inc. Apparatus and methods for laser-based single cell recovery from microcapillary arrays
US12209985B2 (en) * 2020-09-18 2025-01-28 Visera Technologies Company Limited Sensor device and method of using the same
KR102595551B1 (ko) * 2021-06-23 2023-10-30 (주)옵토레인 다중 친수성을 갖는 체외진단칩
KR102674118B1 (ko) * 2021-07-08 2024-06-12 (주)옵토레인 Pcr 모듈
KR20230138571A (ko) 2022-03-23 2023-10-05 삼성전자주식회사 바이오 입자 검출 장치 및 방법
CN117019248B (zh) * 2023-08-17 2025-05-02 杭州跃真生物科技有限公司 一种微孔芯片与单细胞分析方法

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3473927A (en) * 1965-12-14 1969-10-21 Corning Glass Works Double negative exposure method for photosensitively opacifiable glass
JPS582240A (ja) * 1981-06-26 1983-01-07 Hoya Corp 化学切削性感光ガラスの露光方法
US6143496A (en) * 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US20020015997A1 (en) * 1997-06-16 2002-02-07 Lafferty William Michael Capillary array-based sample screening
WO1999034920A1 (en) * 1998-01-12 1999-07-15 Massachusetts Institute Of Technology Method and apparatus for performing microassays
US6893877B2 (en) * 1998-01-12 2005-05-17 Massachusetts Institute Of Technology Methods for screening substances in a microwell array
US6027695A (en) * 1998-04-01 2000-02-22 Dupont Pharmaceuticals Company Apparatus for holding small volumes of liquids
AU3649199A (en) * 1998-04-17 1999-11-08 Ljl Biosystems, Inc. Sample-holding devices and systems
US6511793B1 (en) * 1999-03-24 2003-01-28 Lg Electronics Inc. Method of manufacturing microstructure using photosensitive glass substrate
US20040132166A1 (en) * 2001-04-10 2004-07-08 Bioprocessors Corp. Determination and/or control of reactor environmental conditions
JP3877572B2 (ja) * 2001-08-09 2007-02-07 オリンパス株式会社 微細流路装置およびその使用方法
US20030044320A1 (en) * 2001-08-31 2003-03-06 Shun Luo High throughput screening micro array platform
WO2003042697A1 (en) * 2001-11-14 2003-05-22 Genospectra, Inc. Biochemical analysis system with combinatorial chemistry applications
US7258839B2 (en) * 2001-12-21 2007-08-21 Cytonome, Inc. Temperature controlled microfabricated two-pin liquid sample dispensing system
US7241420B2 (en) * 2002-08-05 2007-07-10 Palo Alto Research Center Incorporated Capillary-channel probes for liquid pickup, transportation and dispense using stressy metal
US7341865B1 (en) * 2002-10-25 2008-03-11 Perlegen Sciences, Inc. Liquid delivery devices and methods
US20060094108A1 (en) * 2002-12-20 2006-05-04 Karl Yoder Thermal cycler for microfluidic array assays
EP1608952B1 (en) * 2002-12-20 2016-08-10 Life Technologies Corporation Assay apparatus and method using microfluidic arrays
US20060233671A1 (en) * 2003-09-19 2006-10-19 Beard Nigel P High density plate filler
WO2005028629A2 (en) * 2003-09-19 2005-03-31 Applera Corporation Whole genome expression analysis system
US20050221358A1 (en) * 2003-09-19 2005-10-06 Carrillo Albert L Pressure chamber clamp mechanism
US20060088857A1 (en) * 2003-12-01 2006-04-27 Said Attiya Method for isolation of independent, parallel chemical micro-reactions using a porous filter
US20050264805A1 (en) * 2004-02-09 2005-12-01 Blueshift Biotechnologies, Inc. Methods and apparatus for scanning small sample volumes
JP2008504845A (ja) * 2004-06-07 2008-02-21 バイオプロセッサーズ コーポレイション リアクター環境条件の制御
EP1614460A1 (en) * 2004-07-08 2006-01-11 Yamatake Corporation Substrate for biochips
US20060057209A1 (en) 2004-09-16 2006-03-16 Predicant Biosciences, Inc. Methods, compositions and devices, including microfluidic devices, comprising coated hydrophobic surfaces
US20060105453A1 (en) 2004-09-09 2006-05-18 Brenan Colin J Coating process for microfluidic sample arrays
US7315019B2 (en) * 2004-09-17 2008-01-01 Pacific Biosciences Of California, Inc. Arrays of optical confinements and uses thereof
EP1693337A1 (de) * 2005-02-18 2006-08-23 Infineon Technologies AG Makroporöser Träger für chemische Amplifikationsreaktionen
EP1882189A2 (en) * 2005-04-20 2008-01-30 Fluidigm Corporation Analysis engine and database for manipulating parameters for fluidic systems on a chip
JP4657803B2 (ja) * 2005-05-19 2011-03-23 富士フイルム株式会社 送液システム及びその送液方法並びに流路ユニット。
US20070081163A1 (en) * 2005-06-03 2007-04-12 Minhua Liang Method and apparatus for scanned beam microarray assay
DK1907571T3 (da) * 2005-06-15 2017-08-21 Complete Genomics Inc Nukleinsyreanalyse ved hjælp af tilfældige blandinger af ikke-overlappende fragmenter
NL1030102C2 (nl) * 2005-10-03 2007-04-04 Ccm Beheer Bv Fluorescentiemicroscoop.
WO2007062218A1 (en) * 2005-11-23 2007-05-31 Bioprocessors Corp. Method for performing fed-batch operations in small volume reactors
US7998708B2 (en) * 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
WO2008063135A1 (en) * 2006-11-24 2008-05-29 Agency For Science, Technology And Research Apparatus for processing a sample in a liquid droplet and method of using the same
AU2008209561A1 (en) * 2007-01-22 2008-07-31 Wafergen, Inc. Apparatus for high throughput chemical reactions
JPWO2009004911A1 (ja) * 2007-07-04 2010-08-26 日本電気株式会社 マイクロチップとこれを用いた分析方法
WO2010008480A2 (en) * 2008-06-25 2010-01-21 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes using large scale fet arrays
JP2010127890A (ja) * 2008-12-01 2010-06-10 Shimadzu Corp 反応容器プレート及び反応処理方法
JP5780487B2 (ja) * 2009-06-01 2015-09-16 日本電気硝子株式会社 ガラス基板の製造方法
US8758633B1 (en) * 2009-07-28 2014-06-24 Clemson University Dielectric spectrometers with planar nanofluidic channels
US8980550B2 (en) * 2009-12-15 2015-03-17 California Institute Of Technology Methods for measuring samples using consumer electronic devices and systems
US8709702B2 (en) * 2010-02-10 2014-04-29 3D Glass Solutions Methods to fabricate a photoactive substrate suitable for microfabrication
AU2013231955A1 (en) * 2012-03-16 2014-10-30 Life Technologies Corporation Systems and methods for loading liquid samples

Also Published As

Publication number Publication date
CN104302400A (zh) 2015-01-21
EP2825314A1 (en) 2015-01-21
AU2013231910A1 (en) 2014-10-30
KR20140140080A (ko) 2014-12-08
RU2014140837A (ru) 2016-05-10
US20150044686A1 (en) 2015-02-12
EP2825310A2 (en) 2015-01-21
SG11201406039WA (en) 2014-11-27
RU2014141637A (ru) 2016-05-10
KR20150003738A (ko) 2015-01-09
US20190381502A1 (en) 2019-12-19
SG11201405785WA (en) 2014-11-27
US20150080247A1 (en) 2015-03-19
WO2013138706A3 (en) 2014-01-16
JP2015511015A (ja) 2015-04-13
JP2015516802A (ja) 2015-06-18
WO2013138767A1 (en) 2013-09-19
CN104411408A (zh) 2015-03-11
US11590506B2 (en) 2023-02-28
US20230201839A1 (en) 2023-06-29
CN104302400B (zh) 2017-03-01
WO2013138706A2 (en) 2013-09-19
CN104411408B (zh) 2017-07-11

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