IN2014DN08505A - - Google Patents
Info
- Publication number
- IN2014DN08505A IN2014DN08505A IN8505DEN2014A IN2014DN08505A IN 2014DN08505 A IN2014DN08505 A IN 2014DN08505A IN 8505DEN2014 A IN8505DEN2014 A IN 8505DEN2014A IN 2014DN08505 A IN2014DN08505 A IN 2014DN08505A
- Authority
- IN
- India
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/12—Triazine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/30—Vaccines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261610411P | 2012-03-13 | 2012-03-13 | |
| PCT/US2013/030196 WO2013138236A1 (en) | 2012-03-13 | 2013-03-11 | 2'- substituted carba-nucleoside analogs for antiviral treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN08505A true IN2014DN08505A (ru) | 2015-05-15 |
Family
ID=47997868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN8505DEN2014 IN2014DN08505A (ru) | 2012-03-13 | 2014-10-10 |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US9481704B2 (ru) |
| EP (4) | EP3210993B1 (ru) |
| JP (3) | JP6242378B2 (ru) |
| KR (1) | KR102068856B1 (ru) |
| CN (2) | CN106749272B (ru) |
| AU (2) | AU2013232378B2 (ru) |
| CA (1) | CA2866381C (ru) |
| EA (2) | EA028928B9 (ru) |
| ES (4) | ES2878087T3 (ru) |
| IL (2) | IL234586A (ru) |
| IN (1) | IN2014DN08505A (ru) |
| MD (1) | MD4496C1 (ru) |
| MX (1) | MX355267B (ru) |
| NZ (1) | NZ629996A (ru) |
| PL (1) | PL2834258T3 (ru) |
| PT (1) | PT2834258T (ru) |
| SI (1) | SI2834258T1 (ru) |
| WO (1) | WO2013138236A1 (ru) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG171914A1 (en) | 2008-12-02 | 2011-07-28 | Chiralgen Ltd | Method for the synthesis of phosphorus atom modified nucleic acids |
| EP2451461A4 (en) | 2009-07-06 | 2013-05-29 | Ontorii Inc | NOVEL NUCLEIC ACID PRODRUGS AND METHOD OF USE THEREOF |
| DK2620428T3 (da) | 2010-09-24 | 2019-07-01 | Wave Life Sciences Ltd | Asymmetrisk hjælpegruppe |
| US9605019B2 (en) | 2011-07-19 | 2017-03-28 | Wave Life Sciences Ltd. | Methods for the synthesis of functionalized nucleic acids |
| US8633198B1 (en) | 2011-09-20 | 2014-01-21 | Nant Holdings Ip, Llc | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase |
| SG10201610936RA (en) | 2011-12-22 | 2017-02-27 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| KR102068856B1 (ko) * | 2012-03-13 | 2020-01-21 | 길리애드 사이언시즈, 인코포레이티드 | 항바이러스 치료를 위한 2'-치환된 카바-뉴클레오시드 유사체 |
| RS58437B1 (sr) * | 2012-03-21 | 2019-04-30 | Alios Biopharma Inc | Supstituisani nukleozidi, nukleotidi i njihovi analozi |
| USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| DK2872485T3 (da) | 2012-07-13 | 2021-03-08 | Wave Life Sciences Ltd | Asymmetrisk hjælpegruppe |
| UA119050C2 (uk) * | 2013-11-11 | 2019-04-25 | Ґілеад Саєнсиз, Інк. | ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ |
| WO2015088516A1 (en) * | 2013-12-11 | 2015-06-18 | Nant Holdings Ip, Llc | Small molecule inhibitors of influenza a rna-dependent rna polymerase |
| KR102423317B1 (ko) | 2014-01-16 | 2022-07-22 | 웨이브 라이프 사이언시스 리미티드 | 키랄 디자인 |
| MA39317A1 (fr) * | 2014-02-06 | 2018-01-31 | Riboscience Llc | Dérivés de nucléosides à substitution 4'-difluorométhyle utilisés en tant qu'inhibiteurs de la réplication de l'arn du virus de la grippe |
| WO2015143712A1 (en) * | 2014-03-28 | 2015-10-01 | Merck Sharp & Dohme Corp. | 4'-substituted nucleoside reverse transcriptase inhibitors |
| TWI678369B (zh) | 2014-07-28 | 2019-12-01 | 美商基利科學股份有限公司 | 用於治療呼吸道合胞病毒感染之噻吩並［３,２-ｄ］嘧啶、呋喃並［３,２-ｄ］嘧啶及吡咯並［３,２-ｄ］嘧啶化合物類 |
| BR112017006264A2 (pt) | 2014-09-26 | 2017-12-12 | Riboscience Llc | derivados de nucleosídeo substituído com 4?-vinila como inibidores de replicação de rna do vírus sincitial respiratório |
| IL296496B2 (en) | 2014-12-26 | 2024-10-01 | Univ Emory | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
| MX391226B (es) | 2015-09-23 | 2025-03-21 | Merck Sharp & Dohme Llc | Inhibidores de transcriptasa inversa de nucleosido 4'-substituido y preparaciones de los mismos. |
| US10202412B2 (en) | 2016-07-08 | 2019-02-12 | Atea Pharmaceuticals, Inc. | β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections |
| ES2901875T3 (es) | 2017-04-24 | 2022-03-24 | Cocrystal Pharma Inc | Derivados de la pirrolopirimidina útiles como inhibidores de la replicación del virus de la influenza |
| KR102626210B1 (ko) | 2017-12-07 | 2024-01-18 | 에모리 유니버시티 | N4-하이드록시사이티딘 및 유도체 및 이와 관련된 항-바이러스 용도 |
| US11040975B2 (en) | 2017-12-08 | 2021-06-22 | Merck Sharp & Dohme Corp. | Carbocyclic nucleoside reverse transcriptase inhibitors |
| WO2020023813A1 (en) | 2018-07-27 | 2020-01-30 | Cocrystal Pharma, Inc. | Pyrrolo[2,3-b]pyridin derivatives as inhibitors of influenza virus replication |
| EP3849978B1 (en) | 2018-09-10 | 2022-11-02 | Cocrystal Pharma, Inc. | Pyridopyrazine and pyridotriazine inhibitors of influenza virus replication |
| US12565488B2 (en) | 2018-11-26 | 2026-03-03 | Cocrystal Pharma, Inc. | Inhibitors of influenza virus replication |
| TWI794742B (zh) | 2020-02-18 | 2023-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| AU2021224588B2 (en) | 2020-02-18 | 2024-07-18 | Gilead Sciences, Inc. | Antiviral compounds |
| TWI874791B (zh) | 2020-02-18 | 2025-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| CN115315252A (zh) * | 2020-03-22 | 2022-11-08 | 盈擘医药股份有限公司 | 用于预防或暴露后治疗感染或呼吸疾病的抗病毒组合物 |
| BR112022019486A2 (pt) * | 2020-03-30 | 2022-11-16 | Fujifilm Toyama Chemical Co Ltd | Agente terapêutico para infecção por coronavírus |
| CN111956630A (zh) * | 2020-08-20 | 2020-11-20 | 大连理工大学 | 一种瑞德西韦供雾化器用的液体制剂、制备方法及其应用 |
| JP7688152B2 (ja) | 2021-04-16 | 2025-06-03 | ギリアード サイエンシーズ， インコーポレイテッド | アミドを使用してカルバヌクレオシドを調製する方法 |
| JP7719954B2 (ja) | 2021-08-18 | 2025-08-06 | ギリアード サイエンシーズ， インコーポレイテッド | リン脂質化合物並びにその製造方法及び使用方法 |
| WO2023022216A1 (ja) * | 2021-08-20 | 2023-02-23 | 塩野義製薬株式会社 | ウイルス増殖抑制作用を有するヌクレオシド誘導体及びそれらのプロドラッグ |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3361306A (en) | 1966-03-31 | 1968-01-02 | Merck & Co Inc | Aerosol unit dispensing uniform amounts of a medically active ingredient |
| US3565070A (en) | 1969-02-28 | 1971-02-23 | Riker Laboratories Inc | Inhalation actuable aerosol dispenser |
| FR2224175B1 (ru) | 1973-04-04 | 1978-04-14 | Isf Spa | |
| US4069819A (en) * | 1973-04-13 | 1978-01-24 | Societa Farmaceutici S.P.A. | Inhalation device |
| IT1017153B (it) | 1974-07-15 | 1977-07-20 | Isf Spa | Apparecchio per inalazioni |
| SE438261B (sv) | 1981-07-08 | 1985-04-15 | Draco Ab | Anvendning i dosinhalator av ett perforerat membran |
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| US4805811A (en) | 1985-03-29 | 1989-02-21 | Aktiebolaget Draco | Dosage device |
| SE448277B (sv) | 1985-04-12 | 1987-02-09 | Draco Ab | Indikeringsanordning vid en doseringsanordning for lekemedel |
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| SI1355916T1 (sl) * | 2001-01-22 | 2007-04-30 | Merck & Co Inc | Nukleozidni derivati kot inhibitorji RNA-odvisne RNA virusne polimeraze |
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| EP2313102A2 (en) | 2008-07-03 | 2011-04-27 | Biota Scientific Management | Bycyclic nucleosides and nucleotides as therapeutic agents |
| AU2010295373B2 (en) * | 2009-09-21 | 2016-09-29 | Gilead Sciences, Inc. | 2' -fluoro substituted carba-nucleoside analogs for antiviral treatment |
| US8455451B2 (en) * | 2009-09-21 | 2013-06-04 | Gilead Sciences, Inc. | 2'-fluoro substituted carba-nucleoside analogs for antiviral treatment |
| WO2011035250A1 (en) * | 2009-09-21 | 2011-03-24 | Gilead Sciences, Inc. | Processes and intermediates for the preparation of 1'-substituted carba-nucleoside analogs |
| ES2524356T3 (es) * | 2010-07-22 | 2014-12-05 | Gilead Sciences, Inc. | Métodos y compuestos para tratar infecciones provocadas por virus Paramyxoviridae |
| TW201305185A (zh) * | 2010-09-13 | 2013-02-01 | 吉李德科學股份有限公司 | 用於抗病毒治療之２’－氟取代之碳－核苷類似物 |
| KR102068856B1 (ko) | 2012-03-13 | 2020-01-21 | 길리애드 사이언시즈, 인코포레이티드 | 항바이러스 치료를 위한 2'-치환된 카바-뉴클레오시드 유사체 |
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2013
- 2013-03-11 KR KR1020147028523A patent/KR102068856B1/ko active Active
- 2013-03-11 NZ NZ629996A patent/NZ629996A/en unknown
- 2013-03-11 ES ES18155061T patent/ES2878087T3/es active Active
- 2013-03-11 AU AU2013232378A patent/AU2013232378B2/en active Active
- 2013-03-11 EA EA201491548A patent/EA028928B9/ru unknown
- 2013-03-11 CN CN201611121597.0A patent/CN106749272B/zh active Active
- 2013-03-11 US US13/793,557 patent/US9481704B2/en active Active
- 2013-03-11 EP EP16203290.8A patent/EP3210993B1/en active Active
- 2013-03-11 ES ES13712043.2T patent/ES2621217T3/es active Active
- 2013-03-11 ES ES16203290T patent/ES2709071T3/es active Active
- 2013-03-11 EA EA201791916A patent/EA201791916A1/ru unknown
- 2013-03-11 CN CN201380014318.9A patent/CN104185638A/zh active Pending
- 2013-03-11 MX MX2014011009A patent/MX355267B/es active IP Right Grant
- 2013-03-11 JP JP2015500493A patent/JP6242378B2/ja active Active
- 2013-03-11 PT PT137120432T patent/PT2834258T/pt unknown
- 2013-03-11 EP EP13712043.2A patent/EP2834258B1/en active Active
- 2013-03-11 SI SI201330567A patent/SI2834258T1/sl unknown
- 2013-03-11 EP EP18155061.7A patent/EP3351552B1/en active Active
- 2013-03-11 PL PL13712043T patent/PL2834258T3/pl unknown
- 2013-03-11 MD MDA20140112A patent/MD4496C1/ru active IP Right Grant
- 2013-03-11 EP EP21168626.6A patent/EP3932931B1/en active Active
- 2013-03-11 WO PCT/US2013/030196 patent/WO2013138236A1/en not_active Ceased
- 2013-03-11 CA CA2866381A patent/CA2866381C/en active Active
- 2013-03-11 ES ES21168626T patent/ES3005115T3/es active Active
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2014
- 2014-09-11 IL IL234586A patent/IL234586A/en active IP Right Grant
- 2014-10-10 IN IN8505DEN2014 patent/IN2014DN08505A/en unknown
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2016
- 2016-09-30 US US15/282,492 patent/US20170114086A1/en not_active Abandoned
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2017
- 2017-06-21 JP JP2017121389A patent/JP6525441B2/ja active Active
- 2017-12-18 IL IL256397A patent/IL256397A/en unknown
- 2017-12-19 AU AU2017279590A patent/AU2017279590A1/en not_active Abandoned
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2018
- 2018-06-22 US US16/016,369 patent/US10941177B2/en active Active
- 2018-12-26 JP JP2018242679A patent/JP2019069986A/ja not_active Withdrawn
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2021
- 2021-01-28 US US17/161,065 patent/US11787832B2/en active Active