IN2014DN10236A - - Google Patents

Download PDF

Info

Publication number
IN2014DN10236A
IN2014DN10236A IN10236DEN2014A IN2014DN10236A IN 2014DN10236 A IN2014DN10236 A IN 2014DN10236A IN 10236DEN2014 A IN10236DEN2014 A IN 10236DEN2014A IN 2014DN10236 A IN2014DN10236 A IN 2014DN10236A
Authority
IN
India
Prior art keywords
terpenes
methods
produced
microbial fermentation
pathway enzymes
Prior art date
Application number
Other languages
English (en)
Inventor
Wendy Chen
Fungmin Liew
Michael Koepke
Original Assignee
Lanzatech New Zealand Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49670710&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2014DN10236(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lanzatech New Zealand Ltd filed Critical Lanzatech New Zealand Ltd
Publication of IN2014DN10236A publication Critical patent/IN2014DN10236A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1229—Phosphotransferases with a phosphate group as acceptor (2.7.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01088—Hydroxymethylglutaryl-CoA reductase (1.1.1.88)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01267—1-Deoxy-D-xylulose-5-phosphate reductoisomerase (1.1.1.267)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y117/00—Oxidoreductases acting on CH or CH2 groups (1.17)
    • C12Y117/07—Oxidoreductases acting on CH or CH2 groups (1.17) with an iron-sulfur protein as acceptor (1.17.7)
    • C12Y117/07001—(E)-4-Hydroxy-3-methylbut-2-enyl-diphosphate synthase (1.17.7.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01—Transketolases and transaldolases (2.2.1)
    • C12Y202/01007—1-Deoxy-D-xylulose-5-phosphate synthase (2.2.1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01009—Acetyl-CoA C-acetyltransferase (2.3.1.9)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/03—Acyl groups converted into alkyl on transfer (2.3.3)
    • C12Y203/0301—Hydroxymethylglutaryl-CoA synthase (2.3.3.10)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/0101—(2E,6E)-Farnesyl diphosphate synthase (2.5.1.10), i.e. geranyltranstransferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/0109—All-trans-octaprenyl-diphosphate synthase (2.5.1.90)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01036—Mevalonate kinase (2.7.1.36)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01148—4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (2.7.1.148)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/04—Phosphotransferases with a phosphate group as acceptor (2.7.4)
    • C12Y207/04002—Phosphomevalonate kinase (2.7.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/0706—2-C-Methyl-D-erythritol 4-phosphate cytidylyltransferase (2.7.7.60)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01033—Diphosphomevalonate decarboxylase (4.1.1.33), i.e. mevalonate-pyrophosphate decarboxylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027—Isoprene synthase (4.2.3.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03046—Alpha-farnesene synthase (4.2.3.46)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y406/00—Phosphorus-oxygen lyases (4.6)
    • C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
    • C12Y406/01012—2-C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (4.6.1.12)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/03—Intramolecular oxidoreductases (5.3) transposing C=C bonds (5.3.3)
    • C12Y503/03002—Isopentenyl-diphosphate DELTA-isomerase (5.3.3.2)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
IN10236DEN2014 2012-06-01 2013-06-04 IN2014DN10236A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261654412P 2012-06-01 2012-06-01
PCT/NZ2013/000095 WO2013180584A1 (en) 2012-06-01 2013-06-04 Recombinant microorganisms and uses therefor

Publications (1)

Publication Number Publication Date
IN2014DN10236A true IN2014DN10236A (de) 2015-08-07

Family

ID=49670710

Family Applications (1)

Application Number Title Priority Date Filing Date
IN10236DEN2014 IN2014DN10236A (de) 2012-06-01 2013-06-04

Country Status (10)

Country Link
US (5) US20130323820A1 (de)
EP (3) EP2855662B1 (de)
JP (2) JP6643083B2 (de)
CN (3) CN111304260A (de)
DK (2) DK3346008T3 (de)
EA (1) EA028892B1 (de)
ES (2) ES2841725T3 (de)
IN (1) IN2014DN10236A (de)
PL (2) PL2855662T3 (de)
WO (1) WO2013180584A1 (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130323820A1 (en) * 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
WO2014065271A1 (ja) 2012-10-23 2014-05-01 積水化学工業株式会社 組換え細胞、並びに、イソプレンの生産方法
RU2013146377A (ru) * 2013-10-17 2015-04-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ ИЗОПРЕНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ РОДА Bacillus
CA2936251C (en) 2014-01-28 2017-11-07 Lanzatech New Zealand Limited Method of producing a recombinant microorganism
CA2936252C (en) 2014-01-30 2019-08-20 Lanzatech New Zealand Limited Recombinant acetogenic bacterium with mutated lactate biosynthesis pathway enzyme and methods of use thereof
JP6325862B2 (ja) * 2014-03-25 2018-05-16 積水化学工業株式会社 組換え細胞、並びに、環式モノテルペンの生産方法
JP2016059313A (ja) * 2014-09-17 2016-04-25 積水化学工業株式会社 組換え細胞、並びに、イソプレン又は環式イソプレノイドの生産方法
US10113194B2 (en) 2014-10-22 2018-10-30 Lanzatech New Zealand Limited Gas testing unit and method
FI3209786T3 (fi) 2014-10-22 2023-06-13 Lanzatech Nz Inc Monivaiheisia bioreaktoriprosesseja
DK3230459T3 (da) * 2014-12-08 2020-12-07 Lanzatech New Zealand Ltd Rekombinante mikroorganismer med øget strømning gennem en fermenteringsbane
WO2016138050A1 (en) 2015-02-23 2016-09-01 Lanzatech New Zealand Limited Recombinant acetogenic bacterium for the conversion of methane to products
DE102015103608A1 (de) * 2015-03-11 2016-09-15 Basf Se Verfahren zur mikrobiellen de novo Synthese von Terpenen
US20170145441A1 (en) 2015-08-17 2017-05-25 INVISTA North America S.à.r.l. Methods, hosts, and reagents related thereto for production of unsaturated pentahydrocarbons, derivatives and intermediates thereof
US10167487B2 (en) 2015-08-17 2019-01-01 INVISTA North America S.à.r.l. Methods, cells and reagents for production of isoprene, derivatives and intermediates thereof
CA3151149C (en) 2015-10-13 2024-03-26 Lanzatech Nz, Inc. Genetically engineered bacterium comprising energy-generating fermentation pathway
US20180334657A1 (en) * 2015-11-30 2018-11-22 Sekisui Chemical Co., Ltd. Recombinant cell, method for producing recombinant cell, and method for producing organic compound
CN108431208A (zh) * 2015-12-03 2018-08-21 朗泽科技新西兰有限公司 增补精氨酸以改善气体发酵产乙酸菌的效率
US10358661B2 (en) 2015-12-28 2019-07-23 Lanzatech New Zealand Limited Microorganism with modified hydrogenase activity
PT3411489T (pt) 2016-02-01 2023-08-07 Lanzatech Nz Inc Processo de fermentação e eletrólise integrado
EP3420089B1 (de) 2016-02-26 2021-12-29 LanzaTech NZ, Inc. Crispr/cas-systeme für c-1-fixierbakterien
WO2017200884A1 (en) 2016-05-14 2017-11-23 Lanzatech, Inc. Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods
JPWO2018070141A1 (ja) * 2016-10-13 2019-08-08 積水化学工業株式会社 偏性嫌気性酢酸生成微生物、並びに、組換え微生物
KR102000755B1 (ko) * 2016-12-27 2019-07-17 한국과학기술원 외부 유전자가 도입된 재조합 미생물 및 상기 미생물을 이용하여 개미산과 이산화탄소로부터 유용물질을 제조하는 방법
GB201701548D0 (en) * 2017-01-31 2017-03-15 Univ Manchester Process for producing monoterpenes
CN110268058B (zh) 2017-02-27 2023-11-21 积水化学工业株式会社 重组细胞、重组细胞的制备方法以及异戊二烯或萜烯的生产方法
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
CN111051517B (zh) 2017-09-08 2023-10-27 朗泽科技有限公司 用于使用富氢气的含有c1的底物生产代谢物的方法和系统
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
CN109722404B (zh) * 2017-10-30 2021-03-12 中国石油化工股份有限公司 利用纤维素制备金合欢烯的工程菌株及方法
CA3084263A1 (en) 2017-12-07 2019-06-13 Zymergen Inc. Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation
US11555209B2 (en) 2017-12-19 2023-01-17 Lanzatech, Inc. Microorganisms and methods for the biological production of ethylene glycol
BR112020012704A8 (pt) 2017-12-21 2022-03-03 Zymergen Inc Nepetalactol oxidorredutases, nepetalactol sintases, e micróbios capazes de produzir nepetalactona
CN111683731B (zh) 2018-02-12 2022-09-02 朗泽科技有限公司 用于提高碳转化效率的工艺
KR102122898B1 (ko) * 2018-02-26 2020-06-15 주식회사 엠디헬스케어 블라우티아 속 세균 유래 나노소포 및 이의 용도
US11053517B2 (en) 2018-04-20 2021-07-06 Lanzatech, Inc. Intermittent electrolysis streams
CN112955558A (zh) 2018-11-19 2021-06-11 朗泽科技有限公司 发酵和气化的集成
CN112969795A (zh) 2019-02-08 2021-06-15 朗泽科技有限公司 用于回收沸点接近的产物的方法
CN109666683B (zh) * 2019-02-27 2021-10-29 昆明理工大学 乙酰辅酶A乙酰转移酶基因RKAcaT2及其应用
WO2020188033A1 (en) 2019-03-20 2020-09-24 Global Bioenergies Improved means and methods for producing isobutene from acetyl-coa
CN109777815B (zh) * 2019-03-28 2021-10-29 昆明理工大学 HMG-CoA合成酶基因RKHMGCS及其应用
WO2021006995A1 (en) 2019-07-11 2021-01-14 Lanzatech, Inc. Methods for optimizing gas utilization
CN110702821B (zh) * 2019-11-26 2022-06-07 四川大学华西医院 一种慢性阻塞性肺疾病分型检测试剂盒
US11976310B2 (en) 2020-02-17 2024-05-07 Scientist Of Fortune S.A. Method for the incorporation of formaldehyde into biomass
US11932818B2 (en) 2020-03-16 2024-03-19 Lanzatech, Inc. Tail gas of gas fermentation to dry gasification feedstock
JP2023518045A (ja) 2020-03-18 2023-04-27 ランザテク，インコーポレイテッド ガス基質からの２－フェニルエタノールの発酵産生
KR20220159450A (ko) 2020-04-29 2022-12-02 란자테크, 인크. 가스성 기질로부터의 β-케토아디페이트의 발효 제조
US11760989B2 (en) 2020-06-06 2023-09-19 Lanzatech, Inc. Microorganism with knock-in at acetolactate decarboxylase gene locus
US11788092B2 (en) 2021-02-08 2023-10-17 Lanzatech, Inc. Recombinant microorganisms and uses therefor
CN115181803B (zh) * 2021-04-07 2025-03-21 暨南大学 检测多子小瓜虫的Taqman探针qPCR检测引物组和应用
JP2024513395A (ja) 2021-04-09 2024-03-25 ランザテク，インコーポレイテッド 供給原料を提供するためのプロセス及び装置
US12241105B2 (en) 2021-07-20 2025-03-04 Lanzatech, Inc. Recombinant microorganisms and uses therefor
TW202307202A (zh) 2021-08-06 2023-02-16 美商朗澤科技有限公司 用於改良乙二醇之生物產生的微生物及方法
EP4144838A1 (de) 2021-09-06 2023-03-08 Global Bioenergies Organismen, die weniger crotonsäure produzieren
US20250327097A1 (en) 2021-09-06 2025-10-23 Global Bioenergies Organisms producing less crotonic acid
US12091648B2 (en) 2021-11-03 2024-09-17 Lanzatech, Inc. System and method for generating bubbles in a vessel
US12280331B2 (en) 2022-04-29 2025-04-22 Lanzatech, Inc. Low residence time gas separator
US12077800B2 (en) 2022-06-16 2024-09-03 Lanzatech, Inc. Liquid distributor system and process of liquid distribution
AU2023286621A1 (en) 2022-06-21 2025-01-09 Lanzatech, Inc. Microorganisms and methods for the continuous co-production of tandem repeat proteins and chemical products from c1-substrates
CN119403929A (zh) 2022-06-21 2025-02-07 朗泽科技有限公司 用于由c1底物连续共产生高价值专用蛋白和化学产物的微生物和方法
US12129503B2 (en) 2022-08-10 2024-10-29 Lanzatech, Inc. Carbon sequestration in soils with production of chemical products
WO2024253882A1 (en) 2023-06-05 2024-12-12 Lanzatech, Inc. Integrated gas fermentation
US12359224B2 (en) 2023-06-05 2025-07-15 Lanzatech, Inc. Integrated gas fermentation and carbon black processes
CN119876212A (zh) * 2025-03-25 2025-04-25 江西农业大学 一种瘤胃丁酸弧菌RnfC蛋白的原核表达纯化方法

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2002A (en) 1841-03-12 Tor and planter for plowing
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
US5593886A (en) 1992-10-30 1997-01-14 Gaddy; James L. Clostridium stain which produces acetic acid from waste gases
US6531303B1 (en) * 1998-07-06 2003-03-11 Arkion Life Sciences Llc Method of producing geranylgeraniol
UA72220C2 (uk) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання
WO2002008438A2 (en) 2000-07-25 2002-01-31 Bioengineering Resources, Inc. Methods for increasing the production of ethanol from microbial fermentation
DE60228439D1 (de) * 2001-06-06 2008-10-02 Dsm Ip Assets Bv Verbesserte isoprenoid herstellung
NZ546496A (en) 2006-04-07 2008-09-26 Lanzatech New Zealand Ltd Gas treatment process
WO2007136847A2 (en) * 2006-05-19 2007-11-29 The Regents Of The University Of California Methods for increasing isoprenoid and isoprenoid precursor production by modulating fatty acid levels
US7704723B2 (en) 2006-08-31 2010-04-27 The Board Of Regents For Oklahoma State University Isolation and characterization of novel clostridial species
DK2066778T3 (en) * 2006-09-26 2016-04-18 Amyris Biotechnologies Inc PREPARATION OF ISOPRENOIDS AND ISOPRENOID PRECURSORS
NZ553984A (en) 2007-03-19 2009-07-31 Lanzatech New Zealand Ltd Alcohol production process
WO2008137092A2 (en) * 2007-05-01 2008-11-13 Acidophil, Llc Methods for the direct conversion of carbon dioxide into a hydrocarbon using a metabolically engineered photosynthetic microorganism
US20090082495A1 (en) * 2007-09-20 2009-03-26 Rene Jean Zimmer Pneumatic Tire
JP2010539902A (ja) * 2007-09-20 2010-12-24 アミリス バイオテクノロジーズ，インコーポレイティド イソプレノイドの生産
JP5600296B2 (ja) 2007-11-13 2014-10-01 ランザテク・ニュージーランド・リミテッド 新規細菌及びその使用法
AU2008334945C1 (en) * 2007-12-13 2013-09-05 Danisco Us Inc. Compositions and methods for producing isoprene
CA2712779C (en) * 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
EP2285948B1 (de) * 2008-03-03 2014-01-08 Joule Unlimited Technologies, Inc. Konstruierte co2 fixierende mikroorganismen, die interessierende produkte auf kohlenstoffbasis produzieren
CN102317463B (zh) 2008-06-09 2014-12-03 蓝瑟科技纽西兰有限公司 厌氧微生物发酵生产丁二醇
US8609371B2 (en) * 2008-08-12 2013-12-17 Allylix, Inc. Isoprenoid compounds
SG172806A1 (en) * 2008-12-30 2011-08-29 Danisco Us Inc Methods of producing isoprene and a co-product
TWI427149B (zh) * 2009-06-17 2014-02-21 Danisco Us Inc 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造
US8759047B2 (en) * 2009-09-16 2014-06-24 Coskata, Inc. Process for fermentation of syngas from indirect gasification
PL2516656T3 (pl) 2009-12-22 2014-10-31 Global Bioenergies Sposób otrzymywania izoprenolu z mewalonianu z zastosowaniem dekarboksylazy difosfomewalonianu
WO2011112103A1 (en) 2010-03-10 2011-09-15 Lanzatech New Zealand Limited Acid production by fermentation
US8143037B2 (en) 2010-03-19 2012-03-27 Coskata, Inc. Ethanologenic Clostridium species, Clostridium coskatii
CN103025688A (zh) * 2010-06-17 2013-04-03 丹尼斯科美国公司 包含异戊二烯衍生物的燃料组合物
US8987431B2 (en) * 2010-07-01 2015-03-24 Coskata, Inc. Essential genes encoding conserved metabolic pathway function in autotrophic solventogenic clostridial species
CA2786903C (en) 2010-07-28 2015-01-20 Lanzatech New Zealand Limited Novel bacteria and methods of use thereof for producing ethanol and acetate
WO2012019169A1 (en) * 2010-08-06 2012-02-09 Danisco Us Inc. Production of isoprene under neutral ph conditions
US20120045807A1 (en) * 2010-08-19 2012-02-23 Lanzatech New Zealand Limited Process for producing chemicals using microbial fermentation of substrates comprising carbon monoxide
WO2012026833A1 (en) 2010-08-26 2012-03-01 Lanzatech New Zealand Limited Process for producing ethanol and ethylene via fermentation
WO2012034023A2 (en) * 2010-09-10 2012-03-15 University Of Delaware Recombinant clostridia that fix co2 and co and uses thereof
US20110236941A1 (en) 2010-10-22 2011-09-29 Lanzatech New Zealand Limited Recombinant microorganism and methods of production thereof
US20110256600A1 (en) * 2011-02-02 2011-10-20 Lanzatech New Zealand Limited Recombinant Microorganisms and Methods of Use Thereof
BR112013021524A2 (pt) 2011-02-25 2017-06-13 Lanzatech New Zealand Ltd micro-organismos recombinantes e usos dos mesmos
JP2014528705A (ja) 2011-08-04 2014-10-30 ダニスコ・ユーエス・インク アセトアセチルＣｏＡシンターゼを用いるイソプレン、イソプレノイド前駆体、及びイソプレノイドの生産
EP2753700B1 (de) 2011-09-08 2020-02-19 Lanzatech New Zealand Limited Fermentierungsverfahren
WO2013066568A1 (en) 2011-10-07 2013-05-10 Danisco Us Inc. Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene
US20130273625A1 (en) * 2011-10-07 2013-10-17 Danisco Us Inc. Methods for increasing microbial production of isoprene, isoprenoids, and isoprenoid precursor molecules using glucose and acetate co-metabolism
EP2766492B1 (de) 2011-10-11 2018-06-06 Metabolic Explorer Fermentative Herstellung von Prenol
IN2014DN10168A (de) 2012-05-30 2015-08-21 Lanzatech New Zealand Ltd
US20130323820A1 (en) * 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
WO2013181647A2 (en) * 2012-06-01 2013-12-05 Danisco Us Inc. Compositions and methods of producing isoprene and/or industrrial bio-products using anaerobic microorganisms
CN113186144A (zh) 2012-06-08 2021-07-30 朗泽科技新西兰有限公司 重组微生物和其用途
US9347076B2 (en) 2012-06-21 2016-05-24 Lanzatech New Zealand Limited Recombinant microorganisms that make biodiesel
IN2015DN01365A (de) 2012-08-28 2015-07-03 Lanzatech New Zealand Ltd
WO2015081331A1 (en) 2013-11-29 2015-06-04 Lanzatech New Zealand Limited Methods and systems for improving fermentation efficiency
DK3230459T3 (da) 2014-12-08 2020-12-07 Lanzatech New Zealand Ltd Rekombinante mikroorganismer med øget strømning gennem en fermenteringsbane
CA3151149C (en) 2015-10-13 2024-03-26 Lanzatech Nz, Inc. Genetically engineered bacterium comprising energy-generating fermentation pathway
CA3012054C (en) 2016-03-16 2023-01-17 William Marsh Rice University Microbial synthesis of isoprenoid precursors, isoprenoids and derivatives including prenylated aromatics compounds
US11555209B2 (en) 2017-12-19 2023-01-17 Lanzatech, Inc. Microorganisms and methods for the biological production of ethylene glycol

Also Published As

Publication number Publication date
CN111218418A (zh) 2020-06-02
CN104822823A (zh) 2015-08-05
JP6643083B2 (ja) 2020-02-12
US10913958B2 (en) 2021-02-09
CN104822823B8 (zh) 2020-05-22
WO2013180584A1 (en) 2013-12-05
JP2015519065A (ja) 2015-07-09
US20210062229A1 (en) 2021-03-04
US20230013524A1 (en) 2023-01-19
US20180142265A1 (en) 2018-05-24
US20150191747A1 (en) 2015-07-09
EP2855662A1 (de) 2015-04-08
DK3346008T3 (da) 2021-01-11
US11459589B2 (en) 2022-10-04
DK2855662T3 (en) 2018-06-25
EP2855662B1 (de) 2018-03-21
EA028892B1 (ru) 2018-01-31
EP3346008B1 (de) 2020-10-07
EP2855662A4 (de) 2015-12-30
CN104822823B (zh) 2020-02-14
JP2018110584A (ja) 2018-07-19
PL3346008T3 (pl) 2021-04-19
JP6636550B2 (ja) 2020-01-29
US20130323820A1 (en) 2013-12-05
PL2855662T3 (pl) 2018-08-31
EA201492206A1 (ru) 2015-09-30
EP3795680A1 (de) 2021-03-24
US12286660B2 (en) 2025-04-29
EP3346008A1 (de) 2018-07-11
CN111304260A (zh) 2020-06-19
ES2841725T3 (es) 2021-07-09
ES2674984T3 (es) 2018-07-05

Similar Documents

Publication Publication Date Title
IN2014DN10236A (de)
PH12019501410A1 (en) Novel fermentation systems and methods
WO2012019175A8 (en) Production of malonyl-coa derived products via anaerobic pathways
NZ708842A (en) Processing biomass
WO2018217064A3 (ko) 형질전환된 t세포를 이용한 자연살해세포의 배양방법
MY164882A (en) Recombinant microorganisms make biodiesel
MX2012008738A (es) Microorganismos y metodos para la biosintesis de p-toluato y tereftalato.
WO2015031441A3 (en) Microorganisms engineered to use unconventional sources of phosphorus or sulfur
IN2014CN03467A (de)
EP4234707A3 (de) Integriertes fermentations- und elektrolyseverfahren
NZ590750A (en) Methods and compositions for improving the production of products in microorganisms, especially clostridium phytofermentans
WO2019014310A8 (en) Biological methods for preparing terpenes
GB2459756B (en) Enhanced ABE fermentation with high yielding butanol tolerant Clostridium strains
MY193665A (en) Recombinant microorganisms and uses therefor
WO2014200598A3 (en) Conversion of carbon dioxide utilizing chemoautotrophic microorganisms
WO2009002772A3 (en) Bioreactor
WO2014144210A3 (en) Competitive growth and/or productivity advantage for butanologen microorganism
CA3010562A1 (en) Lactic acid-utilizing bacteria genetically modified to secrete polysaccharide-degrading enzymes
MX351722B (es) Composición que comprende una biomasa microbiana activada.
MY153054A (en) Bioprocessing
EA201491785A1 (ru) Способ ферментации
MY160960A (en) Filamentous fungi having an altered viscosity phenotype
AR091107A1 (es) Proceso para fermentar sustratos gaseosos que contienen monoxido de carbono
MX378401B (es) Cocultivo de propionibacteria y levadura.
MY181195A (en) Method for producing single cell oil from lignocellulosic materials