IN2014DN10550A - - Google Patents

Info

Publication number
IN2014DN10550A
IN2014DN10550A IN10550DEN2014A IN2014DN10550A IN 2014DN10550 A IN2014DN10550 A IN 2014DN10550A IN 10550DEN2014 A IN10550DEN2014 A IN 10550DEN2014A IN 2014DN10550 A IN2014DN10550 A IN 2014DN10550A
Authority
IN
India
Prior art keywords
cerium oxide
multiple sclerosis
oxide nanoparticles
biocompatible
nanoparticles
Prior art date
Application number
Other languages
English (en)
Inventor
Kenneth Joseph Reed
Wendi Ann Costanzo
Joseph Samuel Erlichman
Eric Leslie Bell
Original Assignee
Cerion Entpr Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerion Entpr Llc filed Critical Cerion Entpr Llc
Publication of IN2014DN10550A publication Critical patent/IN2014DN10550A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/244Lanthanides; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00Particle morphology
    • C01P2004/60Particles characterised by their size
    • C01P2004/64Nanometer sized, i.e. from 1-100 nanometer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
IN10550DEN2014 2012-06-13 2013-03-15 IN2014DN10550A (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261689806P 2012-06-13 2012-06-13
US201261690100P 2012-06-18 2012-06-18
US201261795241P 2012-10-12 2012-10-12
US201261796639P 2012-11-16 2012-11-16
PCT/US2013/032318 WO2013187980A1 (fr) 2012-06-13 2013-03-15 Nanoparticules d'oxyde de cérium pour le traitement du stress oxydatif

Publications (1)

Publication Number Publication Date
IN2014DN10550A true IN2014DN10550A (fr) 2015-08-21

Family

ID=48048227

Family Applications (1)

Application Number Title Priority Date Filing Date
IN10550DEN2014 IN2014DN10550A (fr) 2012-06-13 2013-03-15

Country Status (12)

Country Link
US (4) US9034392B2 (fr)
EP (1) EP2861212B1 (fr)
JP (1) JP6174692B2 (fr)
KR (1) KR101990070B1 (fr)
CN (1) CN104812375B (fr)
AU (1) AU2013274901B2 (fr)
CA (1) CA2875206C (fr)
DK (1) DK2861212T3 (fr)
ES (1) ES2617528T3 (fr)
IN (1) IN2014DN10550A (fr)
MX (1) MX2014015251A (fr)
WO (1) WO2013187980A1 (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014DN10550A (fr) 2012-06-13 2015-08-21 Cerion Entpr Llc
US9446070B2 (en) * 2012-06-13 2016-09-20 Cerion, Llc Nanoceria with citric acid additive
AU2014256983B2 (en) 2013-04-25 2018-10-04 Cerion Enterprises, Llc Chelated nanoceria for the treatment of oxidative stress
US10182994B2 (en) * 2014-06-10 2019-01-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nanoparticulate complex of nicotine and cerium oxide and use thereof
BR112017000800A8 (pt) * 2014-07-17 2023-04-25 Biocurity Holdings Inc Tratamento do câncer com uma combinação de radiação, nanoparticulas de óxido de cério, e um agente quimioterápico
JP2018508568A (ja) 2015-01-20 2018-03-29 セリオン,リミティド ライアビリティ カンパニー カタラーゼ様活性を有するeddsでキレート化されたナノセリア
KR101765557B1 (ko) 2015-02-27 2017-08-23 서울대학교산학협력단 생흡수성 전자 스텐트
US11389536B2 (en) 2015-07-17 2022-07-19 BioCurity Pharmaceuticals Inc. Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent
EP3380088A4 (fr) * 2015-11-25 2019-07-31 The Regents of the University of Colorado, A Body Corporate Utilisation de microarn-146a et d'un conjugué de nanoparticules d'oxyde de cérium pour améliorer la cicatrisation et promouvoir la régénération tissulaire
AU2017384425B2 (en) * 2016-12-21 2023-08-31 Nanobiotix Nanoparticles for use for treating a neuronal disorder
AU2018390163B2 (en) 2017-12-19 2024-05-02 Nanobiotix Nanoparticles for use in enhancing brain performances or in treating stress
HUE068741T2 (hu) 2017-12-19 2025-01-28 Nanobiotix Nanorészecskék idegi zavarok kezelésére
WO2020069292A1 (fr) * 2018-09-28 2020-04-02 The Regents Of The University Of Colorado, A Body Corporate Méthode de prévention et de traitement de l'inflammation et de la fibrose pulmonaire
CN111333098B (zh) * 2018-11-30 2022-04-19 中国科学院大连化学物理研究所 二氧化铈纳米立方块的制备方法
CN109806278B (zh) * 2019-02-01 2021-08-10 浙江大学 磷脂聚乙二醇修饰的超小型氧化铈纳米晶的应用
FR3093640B1 (fr) * 2019-03-15 2021-10-01 Biophytis Phytoecdysones et leurs dérivés pour leur utilisation dans le traitement de maladies neuromusculaires
CN109939125B (zh) * 2019-04-22 2021-05-18 南昌大学第二附属医院 一种抗氧化剂及其制备方法与应用
FR3098723B1 (fr) * 2019-07-18 2023-01-13 Bionuclei Traitement ecobiologique des effets secondaires de la radiotherapie.
KR102107760B1 (ko) * 2019-08-28 2020-05-07 한국콜마주식회사 피부 장벽 강화, 피부 보습 및/또는 미세 먼지 차단용 세륨옥사이드 분산액 및 이를 포함하는 화장료 조성물
JP7740020B2 (ja) * 2020-05-27 2025-09-17 東レ株式会社 酸化セリウムのナノ粒子、抗菌剤、抗ウイルス剤および酸化セリウムのナノ粒子の製造方法
CN111773243B (zh) * 2020-07-17 2022-09-23 南京大学 炎症性肠病的药物及其制备方法和用途
CN112007016B (zh) * 2020-09-07 2021-07-23 南京大学 一种纳米缓释制剂及其制备方法和在制备治疗线粒体功能障碍疾病的药物中的应用
CN112494513A (zh) * 2020-12-15 2021-03-16 中国药科大学 一种二氧化铈纳米粒及其制备方法与应用
CN112516294B (zh) * 2020-12-22 2023-04-07 浙江大学 一种氧化铈纳米稳定剂在制备预防过敏性疾病药物中的应用及预防过敏性疾病的药物组合物
CN113546093A (zh) * 2021-07-20 2021-10-26 中国人民解放军陆军军医大学 氧化铈纳米颗粒在制备治疗和预防肾缺血再灌注损伤的药物中的应用
CN113842469B (zh) * 2021-08-25 2024-04-02 中国科学院过程工程研究所 一种囊泡表面原位结晶高催化活性铈纳米晶的递药系统及其制备方法和应用
CN114470326B (zh) * 2021-12-06 2022-09-13 中国人民解放军空军军医大学 一种仿生矿化胶原-糖胺聚糖材料制备方法及其应用
KR102810481B1 (ko) * 2022-01-21 2025-05-19 성균관대학교산학협력단 다발성경화증 치료용 백신
US12521414B2 (en) * 2022-06-08 2026-01-13 National Health Research Institutes Method for preventing or treating urological chronic pelvic pain syndrome
CN116270729A (zh) * 2022-11-09 2023-06-23 西安交通大学医学院第一附属医院 多孔纳米棒状氧化铈在制备治疗特应性皮炎的药物中的应用
CN115737678B (zh) * 2022-11-30 2024-12-20 浙江大学金华研究院 载三苯基膦修饰的氧化铈和全反式维甲酸的脂质体凝胶
CN116180065B (zh) * 2022-12-27 2024-10-08 国科大杭州高等研究院 一种表面改性的镍钛合金材料及其制备方法和应用
CN116036127B (zh) * 2023-01-17 2025-09-23 中国人民解放军陆军军医大学 氧化铈纳米簇在改善慢性肾病中的应用
AU2023424695A1 (en) * 2023-01-18 2025-08-28 Applause Pharma Co., Ltd. Pharmaceutical composition having, as active ingredient, cerium compound that contains trivalent cerium
CN116850147B (zh) * 2023-06-05 2024-05-14 中南大学 Ppc纳米颗粒、其制备方法以及在治疗心肌梗死的药物中的应用

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FR2809637B1 (fr) 2000-06-05 2003-01-24 Rhodia Terres Rares Dispersion colloidale d'un compose de cerium ou d'un compose de cerium et d'au moins un autre element choisi parmi les terres rares et des metaux de transition et comprenant un acide amine
JP3768401B2 (ja) 2000-11-24 2006-04-19 Necエレクトロニクス株式会社 化学的機械的研磨用スラリー
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JP3793802B2 (ja) 2001-07-09 2006-07-05 独立行政法人物質・材料研究機構 個々の粒子がナノサイズに分離したセリア粉末の製造法
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EP1765280A1 (fr) 2004-06-28 2007-03-28 Procyte Corporation Procédés et composition pour la prévention et le traitement de l"hyperpigmentation de la peau
WO2007002662A2 (fr) 2005-06-27 2007-01-04 Edward Via Virginia College Of Osteopathic Medicine Capacites de nanoparticules d'oxyde de cerium anti-inflammatoires, radioprotectrices et renforçant de la longevite
WO2008002323A2 (fr) 2005-12-23 2008-01-03 Eastman Kodak Company Production de grains d'oxyde métallique contenant du cérium
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CN102281945A (zh) * 2008-12-17 2011-12-14 丝润技术有限公司 包含晶格经改造的二氧化铈纳米颗粒的燃料添加剂
US8679344B2 (en) 2008-12-17 2014-03-25 Cerion Technology, Inc. Process for solvent shifting a nanoparticle dispersion
IN2014DN10550A (fr) 2012-06-13 2015-08-21 Cerion Entpr Llc

Also Published As

Publication number Publication date
JP2015525228A (ja) 2015-09-03
WO2013187980A1 (fr) 2013-12-19
US20180250333A1 (en) 2018-09-06
JP6174692B2 (ja) 2017-08-02
US9962406B2 (en) 2018-05-08
CN104812375B (zh) 2017-08-22
EP2861212A1 (fr) 2015-04-22
KR101990070B1 (ko) 2019-06-17
AU2013274901A1 (en) 2014-12-18
US20130337083A1 (en) 2013-12-19
AU2013274901B2 (en) 2017-09-14
ES2617528T3 (es) 2017-06-19
US20150231174A1 (en) 2015-08-20
US9533007B2 (en) 2017-01-03
CA2875206C (fr) 2020-07-14
MX2014015251A (es) 2015-04-13
KR20150028293A (ko) 2015-03-13
DK2861212T3 (en) 2017-03-06
CA2875206A1 (fr) 2013-12-19
CN104812375A (zh) 2015-07-29
US9034392B2 (en) 2015-05-19
US20170100430A1 (en) 2017-04-13
US10729717B2 (en) 2020-08-04
EP2861212B1 (fr) 2016-12-07

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