IN2014MN02467A - - Google Patents

Download PDF

Info

Publication number: IN2014MN02467A
Authority: IN; India
Prior art keywords: tetrahydrothieno; thiazol; dioxo; pyrimidin; difluoro
Prior art date: 2012-06-08

Application number

Other languages

English (en)

Inventor

Suresh Mahadev Kadam

Abraham Thomas

Sukumar Sinha

Sukeerthi Kumar

Bipin Parsottam Kansagra

Sachin Gavhane

Sandeep Bandu Khandagale

Shailesh Pawase

Jayant Prakashrao Patil

Shailendra Bhadane

Bhavna Mishra

Rajesh Dwivedi

Original Assignee

Glenmark Pharmaceuticals Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-06-08

Filing date

2013-06-08

Publication date

2015-07-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54193746&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2014MN02467(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2013-06-08 Application filed by Glenmark Pharmaceuticals Sa filed Critical Glenmark Pharmaceuticals Sa

2013-06-08 Priority to IN2467MUN2014 priority Critical patent/IN2014MN02467A/en

2015-07-10 Publication of IN2014MN02467A publication Critical patent/IN2014MN02467A/en

Links

DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
PQIOSYKVBBWRRI-UHFFFAOYSA-N methylphosphonyl difluoride Chemical group CP(F)(F)=O PQIOSYKVBBWRRI-UHFFFAOYSA-N 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004528 pyrimidin-5-yl group Chemical group N1=CN=CC(=C1)* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000437 thiazol-2-yl group Chemical group [H]C1=C([H])N=C(*)S1 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

IN2467MUN2014 2012-06-08 2013-06-08 IN2014MN02467A (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IN2467MUN2014 IN2014MN02467A (fr)	2012-06-08	2013-06-08

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
IN1687MU2012		2012-06-08
US201261665282P	2012-06-27	2012-06-27
IN3519MU2012		2012-12-13
US201261748016P	2012-12-31	2012-12-31
PCT/IB2013/054703 WO2013183035A2 (fr)	2012-06-08	2013-06-08	Amides de composés de 2-amino-4-arylthiazole et leurs sels
IN2467MUN2014 IN2014MN02467A (fr)	2012-06-08	2013-06-08

Publications (1)

Publication Number	Publication Date
IN2014MN02467A true IN2014MN02467A (fr)	2015-07-10

Family

ID=54193746

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IN2467MUN2014 IN2014MN02467A (fr)	2012-06-08	2013-06-08

Country Status (22)

Country	Link
US (1)	US9458173B2 (fr)
EP (1)	EP2858999B1 (fr)
JP (1)	JP5989900B2 (fr)
KR (1)	KR20150015488A (fr)
CN (1)	CN104350058A (fr)
AP (1)	AP3546A (fr)
AU (1)	AU2013273118B2 (fr)
BR (1)	BR112014029155A2 (fr)
CA (1)	CA2873570C (fr)
CL (1)	CL2014003317A1 (fr)
EA (1)	EA031334B1 (fr)
HK (1)	HK1207643A1 (fr)
IL (1)	IL236084A0 (fr)
IN (1)	IN2014MN02467A (fr)
MX (1)	MX354014B (fr)
MY (1)	MY165622A (fr)
NZ (1)	NZ701721A (fr)
PE (1)	PE20142306A1 (fr)
PH (1)	PH12014502685A1 (fr)
SG (1)	SG11201408093PA (fr)
WO (1)	WO2013183035A2 (fr)
ZA (1)	ZA201500082B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20150040265A (ko)	2012-06-08	2015-04-14	길리애드 사이언시즈, 인코포레이티드	플라비비리대 바이러스의 마크로시클릭 저해제
AR091279A1 (es)	2012-06-08	2015-01-21	Gilead Sciences Inc	Inhibidores macrociclicos de virus flaviviridae
EP3010489A1 (fr)	2013-06-20	2016-04-27	Glenmark Pharmaceuticals S.A.	Formulation nanoparticulaire comprenant un antagoniste de trpa1
WO2016023832A1 (fr) *	2014-08-11	2016-02-18	Hydra Biosciences, Inc.	Dérivés de thiéno- et furo[2,3-d]pyrimidine-2,4(1h,3h)-dione à titre de modulateurs des trpc5 pour le traitement des troubles neuropsychiatriques
WO2016042501A1 (fr) *	2014-09-16	2016-03-24	Glenmark Pharmaceuticals S.A.	Antagoniste de trpa1 permettant le traitement de la douleur associée à la douleur neuropathique diabétique
TW202321229A (zh)	2021-08-18	2023-06-01	美商富曼西公司	殺真菌的取代的雜環化合物
CN114671875A (zh) *	2022-04-27	2022-06-28	成都施贝康生物医药科技有限公司	新型二氢嘧啶类化合物、异构体或盐及其制备方法和用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2248231A1 (de)	1972-10-02	1974-04-11	Basf Ag	3-aminoisothiazolo eckige klammer auf 3,4-d eckige klammer zu pyrimidine
SE9701398D0 (sv)	1997-04-15	1997-04-15	Astra Pharma Prod	Novel compounds
ES2193839B1 (es) *	2001-06-22	2005-02-16	Almirall Prodesfarma, S.A.	Nuevos derivados de 6-fenildihidropirrolpirimidindiona.
AU2003253165A1 (en) *	2002-08-13	2004-02-25	Warner-Lambert Company Llc	Pyrimidine fused bicyclic metalloproteinase inhibitors
US6890923B2 (en)	2002-12-16	2005-05-10	Astrazeneca Ab	Compounds
AU2003290066A1 (en)	2002-12-18	2004-07-09	Novartis Ag	Anktm1, a cold-activated trp-like channel expressed in nociceptive neurons
EP1657238A4 (fr)	2003-08-22	2008-12-03	Takeda Pharmaceutical	Derive de pyrimidine fusionne et utilisation associee
US20070099940A1 (en)	2004-02-11	2007-05-03	Spearing Paul K	Pth agonists
WO2005089206A2 (fr)	2004-03-13	2005-09-29	Irm Llc	Modulateurs du canal ionique trpa1
JPWO2006083005A1 (ja)	2005-02-03	2008-06-26	武田薬品工業株式会社	縮合ピリミジン誘導体およびその用途
WO2007019251A2 (fr)	2005-08-04	2007-02-15	Apogee Biotechnology Corporation	Inhibiteurs de la sphingosine kinase et leurs methodes d'utilisation
US20070105920A1 (en)	2005-11-08	2007-05-10	Akzo Nobel N.V.	2-(Benzimidazol-1-Yl)-N-(4-phenylthiazol-2-yl) acetamide derivatives
CN102499921A (zh) *	2005-12-22	2012-06-20	海德拉生物科学公司	治疗疼痛的方法和组合物
CN101454318A (zh) *	2006-03-22	2009-06-10	阿斯利康(瑞典)有限公司	吡啶并嘧啶衍生物及其作为pde4抑制剂的用途
TW200800997A (en)	2006-03-22	2008-01-01	Astrazeneca Ab	Chemical compounds
JP2011201776A (ja)	2008-07-23	2011-10-13	Mochida Pharmaceut Co Ltd	ヘテロシクリデン−ｎ−（３，４−ジヒドロ−２（１ｈ）−キナゾリノン−５−イル）アセトアミド誘導体
AR065081A1 (es)	2007-01-29	2009-05-13	Xenon Pharmaceuticals Inc	Compuestos de quinazolinona y pirimidona fusionados y composicion farmaceutica
US8163761B2 (en) *	2007-06-22	2012-04-24	Hydra Biosciences, Inc.	Methods and compositions for treating disorders
US7951814B2 (en) *	2008-06-17	2011-05-31	Glenmark Pharmaceuticals, S.A.	Quinazolinedione derivatives as TRPA1 modulators
WO2009158719A2 (fr)	2008-06-27	2009-12-30	Hydra Biosciences, Inc.	Méthodes et compositions de traitement de troubles
EA201190191A1 (ru)	2009-03-23	2012-11-30	Гленмарк Фармасьютикалс, С.А.	Изотиазоло-пиримидинедионовые производные в качестве модуляторов trpa1
US8623880B2 (en)	2009-03-23	2014-01-07	Glenmark Pharmaceuticals S.A.	Fused pyrimidine-dione derivatives as TRPA1 modulators
KR20110128898A (ko)	2009-03-23	2011-11-30	그렌마크 파머수티칼스 에스. 아.	Ｔｒｐａ1 조절자로서 푸로피리미딘디온 유도체
JP5657638B2 (ja)	2009-03-23	2015-01-21	グレンマークファーマシューティカルズ，エセ．アー．	Ｔｒｐａ１調節因子としての縮合ピリミジンジオン誘導体
EA023141B1 (ru)	2010-12-20	2016-04-29	Гленмарк Фармасьютикалс С.А.	Соединения 2-амино-4-арилтиазола в качестве антагонистов trpa1

2013
- 2013-06-08 JP JP2015515642A patent/JP5989900B2/ja not_active Expired - Fee Related
- 2013-06-08 IN IN2467MUN2014 patent/IN2014MN02467A/en unknown
- 2013-06-08 HK HK15108333.2A patent/HK1207643A1/xx unknown
- 2013-06-08 NZ NZ701721A patent/NZ701721A/en not_active IP Right Cessation
- 2013-06-08 CA CA2873570A patent/CA2873570C/fr active Active
- 2013-06-08 MX MX2014014482A patent/MX354014B/es active IP Right Grant
- 2013-06-08 WO PCT/IB2013/054703 patent/WO2013183035A2/fr not_active Ceased
- 2013-06-08 EP EP13742279.6A patent/EP2858999B1/fr active Active
- 2013-06-08 MY MYPI2014003389A patent/MY165622A/en unknown
- 2013-06-08 EA EA201492054A patent/EA031334B1/ru unknown
- 2013-06-08 KR KR1020147033855A patent/KR20150015488A/ko not_active Abandoned
- 2013-06-08 PE PE2014002226A patent/PE20142306A1/es not_active Application Discontinuation
- 2013-06-08 AP AP2014008076A patent/AP3546A/xx active
- 2013-06-08 AU AU2013273118A patent/AU2013273118B2/en not_active Ceased
- 2013-06-08 SG SG11201408093PA patent/SG11201408093PA/en unknown
- 2013-06-08 CN CN201380030184.XA patent/CN104350058A/zh active Pending
- 2013-06-08 US US14/402,608 patent/US9458173B2/en not_active Expired - Fee Related
- 2013-06-08 BR BR112014029155A patent/BR112014029155A2/pt not_active Application Discontinuation
2014
- 2014-12-02 PH PH12014502685A patent/PH12014502685A1/en unknown
- 2014-12-04 IL IL236084A patent/IL236084A0/en unknown
- 2014-12-04 CL CL2014003317A patent/CL2014003317A1/es unknown
2015
- 2015-01-07 ZA ZA2015/00082A patent/ZA201500082B/en unknown

Also Published As

Publication number	Publication date
CA2873570A1 (fr)	2013-12-12
PH12014502685B1 (en)	2015-01-26
US20150111038A1 (en)	2015-04-23
PE20142306A1 (es)	2015-01-16
IL236084A0 (en)	2015-02-01
US9458173B2 (en)	2016-10-04
NZ701721A (en)	2016-03-31
AP3546A (en)	2016-01-14
AP2014008076A0 (en)	2014-11-30
EP2858999A2 (fr)	2015-04-15
EP2858999B1 (fr)	2017-05-10
SG11201408093PA (en)	2015-01-29
KR20150015488A (ko)	2015-02-10
EA201492054A1 (ru)	2016-08-31
AU2013273118A1 (en)	2014-11-27
ZA201500082B (en)	2015-12-23
WO2013183035A2 (fr)	2013-12-12
MY165622A (en)	2018-04-18
AU2013273118B2 (en)	2015-11-05
JP5989900B2 (ja)	2016-09-07
PH12014502685A1 (en)	2015-01-26
MX354014B (es)	2018-02-08
MX2014014482A (es)	2015-06-05
JP2015520183A (ja)	2015-07-16
EA031334B1 (ru)	2018-12-28
CL2014003317A1 (es)	2015-02-13
CA2873570C (fr)	2016-11-01
HK1207643A1 (en)	2016-02-05
BR112014029155A2 (pt)	2017-06-27
WO2013183035A3 (fr)	2014-02-27
CN104350058A (zh)	2015-02-11

Publication	Publication Date	Title
IN2014MN02467A (fr)	2015-07-10
MY161757A (en)	2017-05-15	Meglumine salt of 6-fluoro-3-hydroxy-2-pyrazine carboxamide
PH12015501649A1 (en)	2015-10-05	Sodium salt of 6-fluoro-3-hydroxy-2-pyrazine carboxamide
CO6831982A2 (es)	2014-01-10	Pirazolo[4,3-d]pirimidinas útiles como inhibidores de cinasas
PH12012502138B1 (en)	2019-09-25	N3-substituted-n1-sulfonyl-5-fluoropyrimidinone derivatives
NZ749557A (en)	2020-01-31	3-alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1h)-one derivatives as fungicides
PH12016500250A1 (en)	2016-05-16	Novel triazolo [4,5-d] pyrimidine derivatives
EP2788000A4 (fr)	2015-11-18	Pyrrolopyrimidines en tant qu'inhibiteurs de kinase janus
ZA201306719B (en)	2015-04-29	3,4-dihydro-pyrrolo[1,2-a]pyrazin-1-ylamine derivatives useful as inhibitors of beta-secretase (bace)
MY171831A (en)	2019-11-01	Novel fused pyrimidine compound or salt thereof
EP2938616A4 (fr)	2016-06-15	Procédé de préparation de tofacitinib et d'intermédiaires
MX2013015308A (es)	2014-05-20	Inhibidores de proteasoma y procesos para su preparacion, purificacion y uso.
PH12015500363A1 (en)	2015-04-20	Prodrugs of amino quinazoline kinase inhibitor
NZ701933A (en)	2017-01-27	Phenoxyethyl piperidine compounds
EA201591105A1 (ru)	2015-10-30	ПИРИМИДО[4,5-b]ХИНОЛИН-4,5-(3H,10H)-ДИОНЫ В КАЧЕСТВЕ СУПРЕССОРОВ НОНСЕНС МУТАЦИЙ
MX344911B (es)	2017-01-11	Compuestos de eter amido-piridilico y composiciones y su uso contra parasitos.
PH12015502409B1 (en)	2016-02-22	Pyrrolo[2,3-d]pyrimidine derivatives as cb2 receptor agonists
MX2014010423A (es)	2014-09-22	Sales de arginina utiles inmunologicamente.
GEP20146183B (en)	2014-10-27	Process for preparation of l-arginine salt of perindopril
EP2759529A4 (fr)	2015-05-20	Procédé de préparation de 1-palmitoyl-3-acétylglycérol et procédé de préparation de 1-palmitoyl-2-linoléoyl-3-acétylglycérol l'utilisant
EP2702044A4 (fr)	2014-06-04	Procédé de préparation de rilpivirine
WO2014160177A3 (fr)	2015-05-14	Inhibiteurs quinazolines de pi3k
EP2885302A4 (fr)	2016-03-09	Procédé de préparation d'inhibiteurs de dipeptidylpeptidase
CR20140545A (es)	2015-01-12	Piperazino[1,2-a]indol-1-onas y [1,4]diazepino [1,2-a]indol-1-ona
MY164134A (en)	2017-11-30	Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring