IS2220B - Fjölpeptíð sem geta myndað mótefnavaka bindibyggingar með sértækni fyrir resus D mótefnavökum, DNA-ið sem táknar þau og aðferðin til framleiðslu og notkunar þeirra. - Google Patents

Fjölpeptíð sem geta myndað mótefnavaka bindibyggingar með sértækni fyrir resus D mótefnavökum, DNA-ið sem táknar þau og aðferðin til framleiðslu og notkunar þeirra.

Info

Publication number
IS2220B
IS2220B IS4922A IS4922A IS2220B IS 2220 B IS2220 B IS 2220B IS 4922 A IS4922 A IS 4922A IS 4922 A IS4922 A IS 4922A IS 2220 B IS2220 B IS 2220B
Authority
IS
Iceland
Prior art keywords
antigens
resus
specificity
production
binding sites
Prior art date
Application number
IS4922A
Other languages
English (en)
Other versions
IS4922A (is
Inventor
Miescher Sylvia
Vogel Monique
Stadler Beda
Morell Andreas
Imboden Martin
Amstutz Hanspeter
Original Assignee
Zlb Behring Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zlb Behring Ag filed Critical Zlb Behring Ag
Publication of IS4922A publication Critical patent/IS4922A/is
Publication of IS2220B publication Critical patent/IS2220B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/80—Antibody or fragment thereof whose amino acid sequence is disclosed in whole or in part
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
IS4922A 1996-06-24 1998-12-11 Fjölpeptíð sem geta myndað mótefnavaka bindibyggingar með sértækni fyrir resus D mótefnavökum, DNA-ið sem táknar þau og aðferðin til framleiðslu og notkunar þeirra. IS2220B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96810421 1996-06-24
PCT/EP1997/003253 WO1997049809A1 (en) 1996-06-24 1997-06-20 Polypeptides capable of forming antigen binding structures with specificity for the rhesus d antigens, the dna encoding them and the process for their preparation and use

Publications (2)

Publication Number Publication Date
IS4922A IS4922A (is) 1998-12-11
IS2220B true IS2220B (is) 2007-03-15

Family

ID=8225636

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4922A IS2220B (is) 1996-06-24 1998-12-11 Fjölpeptíð sem geta myndað mótefnavaka bindibyggingar með sértækni fyrir resus D mótefnavökum, DNA-ið sem táknar þau og aðferðin til framleiðslu og notkunar þeirra.

Country Status (23)

Country Link
US (3) US7038020B1 (is)
EP (1) EP0920509B1 (is)
JP (1) JP3841360B2 (is)
KR (1) KR100361449B1 (is)
AT (1) ATE272116T1 (is)
AU (1) AU722127B2 (is)
BG (1) BG64534B1 (is)
BR (1) BR9709958A (is)
CA (1) CA2258494C (is)
CZ (1) CZ296807B6 (is)
DE (1) DE69730031T2 (is)
DK (1) DK0920509T3 (is)
ES (1) ES2224255T3 (is)
HU (1) HUP9902605A3 (is)
IL (1) IL127595A (is)
IS (1) IS2220B (is)
NO (1) NO327947B1 (is)
NZ (1) NZ333329A (is)
PL (1) PL186019B1 (is)
RU (1) RU2204602C2 (is)
SK (1) SK284879B6 (is)
TR (1) TR199802692T2 (is)
WO (1) WO1997049809A1 (is)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000029583A2 (en) * 1998-11-19 2000-05-25 Incyte Pharmaceuticals, Inc. Immunoglobulin superfamily proteins
EP1106625A1 (en) * 1999-11-17 2001-06-13 ZLB Bioplasma AG Rhesus D specific peptide sequences
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
US8288322B2 (en) 2000-04-17 2012-10-16 Dyax Corp. Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
DK1276855T3 (da) 2000-04-17 2012-11-26 Dyax Corp Fremgangsmåde til konstruktion af visningsbiblioteker over genetiske pakker for medlemmer af en diversificeret peptidfamilie
WO2002046435A2 (en) * 2000-12-05 2002-06-13 Alexion Pharmaceuticals, Inc. Engineered plasmids and their use for in situ production of genes
DK1360288T3 (da) 2000-12-18 2011-06-14 Dyax Corp Fokuserede biblioteker af genetiske pakker
AU2016225923B2 (en) * 2001-04-17 2018-07-05 Takeda Pharmaceutical Company Limited Novel Methods of Constructing Libraries Comprising Displayed and/or Expressed Members of a Diverse Family of Peptides, Polypeptides or Proteins and the Novel Libraries
RU2209434C1 (ru) * 2001-11-15 2003-07-27 Российский центр судебно-медицинской экспертизы Министерства здравоохранения Российской Федерации Способ получения резус-пептидов анти-d, специфически выявляющих антиген rhd в следах крови и выделений
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
KR20070038556A (ko) 2004-07-20 2007-04-10 심포젠 에이/에스 항-ｒｈｅｓｕｓ ｄ 재조합 폴리클로날 항체 및 이의 제조방법
AU2005263334C1 (en) 2004-07-20 2011-01-20 Symphogen A/S A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line
GB0706558D0 (en) * 2007-04-03 2007-05-09 Common Services Agency For The Diagnostic assay
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
JP5933894B2 (ja) 2007-09-14 2016-06-15 アディマブ， エルエルシー 合理的に設計された、合成抗体ライブラリおよびその使用
US12529164B2 (en) 2007-09-14 2026-01-20 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
US20090093004A1 (en) 2007-10-04 2009-04-09 Symphogen A/S Potency assay
WO2009114815A1 (en) 2008-03-13 2009-09-17 Dyax Corp Libraries of genetic packages comprising novel hc cdr3 designs
WO2009132287A2 (en) 2008-04-24 2009-10-29 Dyax Corp. Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
KR102810907B1 (ko) 2010-07-16 2025-05-21 아디맵 엘엘씨 항체 라이브러리
KR20150082367A (ko) * 2012-11-06 2015-07-15 메디뮨 엘엘씨 항슈도모나스 ｐｓｌ 및 ｐｃｒｖ 결합 분자를 이용한 병용 요법
CA3079014A1 (en) * 2017-10-20 2019-04-25 Csl Ltd. Method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2127434A (en) 1982-09-17 1984-04-11 Univ London A human monoclonal antibody against Rhesus D antigen
GB8722018D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8925590D0 (en) * 1989-11-13 1990-01-04 Central Blood Lab Authority Monoclonal antibodies

Also Published As

Publication number Publication date
ES2224255T3 (es) 2005-03-01
US7399471B2 (en) 2008-07-15
US7038020B1 (en) 2006-05-02
DE69730031T2 (de) 2005-06-16
CA2258494A1 (en) 1997-12-31
JP2000515732A (ja) 2000-11-28
NO327947B1 (no) 2009-10-26
PL330794A1 (en) 1999-06-07
DK0920509T3 (da) 2004-12-06
IL127595A (en) 2005-09-25
JP3841360B2 (ja) 2006-11-01
KR20000022530A (ko) 2000-04-25
US7429647B2 (en) 2008-09-30
US20060165694A1 (en) 2006-07-27
TR199802692T2 (xx) 1999-03-22
EP0920509B1 (en) 2004-07-28
HUP9902605A3 (en) 2001-11-28
SK176198A3 (en) 1999-07-12
BR9709958A (pt) 1999-08-10
US20050266013A1 (en) 2005-12-01
WO1997049809A1 (en) 1997-12-31
IS4922A (is) 1998-12-11
AU722127B2 (en) 2000-07-20
CZ296807B6 (cs) 2006-06-14
AU3342397A (en) 1998-01-14
ATE272116T1 (de) 2004-08-15
BG103016A (en) 1999-08-31
NZ333329A (en) 2000-07-28
SK284879B6 (sk) 2006-01-05
EP0920509A1 (en) 1999-06-09
PL186019B1 (pl) 2003-09-30
CA2258494C (en) 2008-05-27
CZ395998A3 (cs) 1999-05-12
NO986088L (no) 1999-02-24
HUP9902605A2 (hu) 1999-11-29
IL127595A0 (en) 1999-10-28
NO986088D0 (no) 1998-12-23
RU2204602C2 (ru) 2003-05-20
KR100361449B1 (ko) 2003-01-24
BG64534B1 (bg) 2005-06-30
DE69730031D1 (de) 2004-09-02

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