IS5223A - Lyfjasamsetningar af tizoxaníði og nitazoxaníði - Google Patents

Lyfjasamsetningar af tizoxaníði og nitazoxaníði

Info

Publication number: IS5223A
Authority: IS; Iceland
Prior art keywords: tizoxanide; nitazoxanide; pharmaceutical formulations; formulations; pharmaceutical
Prior art date: 1997-05-07

Application number

IS5223A

Other languages

English (en)

Other versions

IS2087B (is

Inventor

Rossignol Jean-François

Original Assignee

Romark Laboratories L.C.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-07

Filing date

1999-10-19

Publication date

1999-10-19

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS5223(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-05-07 Priority claimed from US08/852,447 external-priority patent/US5968961A/en

1997-07-03 Priority claimed from US08/887,809 external-priority patent/US5965590A/en

1997-07-03 Priority claimed from US08/887,810 external-priority patent/US5856348A/en

1999-10-19 Application filed by Romark Laboratories L.C. filed Critical Romark Laboratories L.C.

1999-10-19 Publication of IS5223A publication Critical patent/IS5223A/is

2006-03-15 Publication of IS2087B publication Critical patent/IS2087B/is

Links

FDTZUTSGGSRHQF-UHFFFAOYSA-N Desacetyl-nitazoxanide Chemical compound OC1=CC=CC=C1C(=O)NC1=NC=C([N+]([O-])=O)S1 FDTZUTSGGSRHQF-UHFFFAOYSA-N 0.000 title 1
YQNQNVDNTFHQSW-UHFFFAOYSA-N acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester Chemical compound CC(=O)OC1=CC=CC=C1C(=O)NC1=NC=C([N+]([O-])=O)S1 YQNQNVDNTFHQSW-UHFFFAOYSA-N 0.000 title 1
229960002480 nitazoxanide Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

IS5223A 1997-05-07 1999-10-19 Lyfjasamsetningar af tizoxaníði og nitazoxaníði IS2087B (is)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US08/852,447 US5968961A (en)	1997-05-07	1997-05-07	Pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,809 US5965590A (en)	1994-09-08	1997-07-03	Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,810 US5856348A (en)	1994-09-08	1997-07-03	Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
PCT/US1998/009229 WO1998050035A1 (en)	1997-05-07	1998-05-06	Pharmaceutical compositions of tizoxanide and nitazoxanide

Publications (2)

Publication Number	Publication Date
IS5223A true IS5223A (is)	1999-10-19
IS2087B IS2087B (is)	2006-03-15

Family

ID=27420362

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5223A IS2087B (is)	1997-05-07	1999-10-19	Lyfjasamsetningar af tizoxaníði og nitazoxaníði

Country Status (34)

Country	Link
EP (2)	EP1005342B1 (is)
JP (1)	JP3739802B2 (is)
KR (2)	KR100426657B1 (is)
CN (2)	CN1158074C (is)
AP (1)	AP1103A (is)
AR (1)	AR057242A2 (is)
AT (2)	ATE228839T1 (is)
AU (1)	AU740022B2 (is)
BG (2)	BG109365A (is)
BR (1)	BR9808722A (is)
CA (2)	CA2288003C (is)
CZ (2)	CZ298270B6 (is)
DE (2)	DE69809928T2 (is)
DK (2)	DK1222921T3 (is)
EA (2)	EA002908B1 (is)
EE (1)	EE04870B1 (is)
ES (2)	ES2150404T3 (is)
GE (1)	GEP20032970B (is)
HU (1)	HU229641B1 (is)
IL (2)	IL132516A (is)
IS (1)	IS2087B (is)
LV (1)	LV12492B (is)
ME (1)	ME00530B (is)
NO (2)	NO313983B1 (is)
NZ (2)	NZ513881A (is)
OA (1)	OA11169A (is)
PL (1)	PL193275B1 (is)
PT (2)	PT1005342E (is)
RO (1)	RO120605B1 (is)
SI (1)	SI20149B (is)
SK (2)	SK283947B6 (is)
TR (1)	TR199902733T2 (is)
UA (2)	UA57079C2 (is)
WO (1)	WO1998050035A1 (is)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2467321A1 (en)	2004-05-14	2005-11-14	Paul J. Santerre	Polymeric coupling agents and pharmaceutically-active polymers made therefrom
AP2907A (en)	2006-01-09	2014-05-31	Romark Lab Lc	Viral hepatitis treatment
EP2395840B1 (en) *	2009-02-13	2020-04-15	Romark Laboratories, L.C.	Controlled release pharmaceutical formulations of nitazoxanide
CN105853415A (zh) *	2009-05-12	2016-08-17	罗马克实验室有限公司	卤代烷基杂芳基苯甲酰胺化合物
MX391013B (es)	2009-06-26	2025-03-21	Romark Laboratories Lc	Compuestos y metodos para tratar influenza.
WO2013110975A1 (es)	2012-01-27	2013-08-01	Siegfried Rhein S.A. De C.V.	Composición de nitazoxanida mejorada y proceso para prepararla
EP3217795A4 (en) *	2014-11-11	2018-08-22	Romark Laboratories, L.C.	Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
CA3087898A1 (en)	2018-02-02	2019-08-08	Ripple Therapeutics Corporation	Glass formulations comprising steroid dimers and uses thereof
WO2019241376A1 (en)	2018-06-14	2019-12-19	The Trustees Of Columbia University In The City Of New York	Treatment of cognitive disorders using nitazoxanide (ntz), nitazoxanide (ntz) analogs, and metabolites thereof
WO2020154815A1 (en)	2019-02-01	2020-08-06	Ripple Therapeutics Corporation	Crystalline forms of dexamethasone dimers and uses thereof
US12509469B2 (en)	2019-08-07	2025-12-30	Ripple Therapeutics Corporation	Compositions and methods for the treatment of pain and dependence disorders
JP2023524494A (ja)	2020-05-01	2023-06-12	リップルセラピューティクスコーポレーション	眼障害を処置するためのヘテロ二量体組成物と方法
WO2022130406A1 (en) *	2020-12-15	2022-06-23	Cipla Limited	Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1437800A (en) *	1973-08-08	1976-06-03	Phavic Sprl	Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) *	1978-12-07	1982-02-09	Rossignol Jean F	Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US5387598A (en) *	1994-04-13	1995-02-07	Rossignol; Jean-Francois	Composition and galenic formulation suitable for combatting affections of the lower abdomen
US5578621A (en) *	1994-09-08	1996-11-26	Romark Lab Lc	Benzamide derivatives

1998
- 1998-05-06 KR KR10-1999-7009930A patent/KR100426657B1/ko not_active Expired - Lifetime
- 1998-05-06 PT PT98920285T patent/PT1005342E/pt unknown
- 1998-05-06 CZ CZ20060366A patent/CZ298270B6/cs not_active IP Right Cessation
- 1998-05-06 DE DE69809928T patent/DE69809928T2/de not_active Expired - Lifetime
- 1998-05-06 DK DK02002887T patent/DK1222921T3/da active
- 1998-05-06 SK SK708-2003A patent/SK283947B6/sk unknown
- 1998-05-06 NZ NZ513881A patent/NZ513881A/xx not_active IP Right Cessation
- 1998-05-06 EP EP98920285A patent/EP1005342B1/en not_active Expired - Lifetime
- 1998-05-06 EP EP02002887A patent/EP1222921B1/en not_active Expired - Lifetime
- 1998-05-06 SK SK1511-99A patent/SK283946B6/sk unknown
- 1998-05-06 EE EEP199900578A patent/EE04870B1/xx unknown
- 1998-05-06 AP APAP/P/1999/001675A patent/AP1103A/en active
- 1998-05-06 KR KR1020037011334A patent/KR100576646B1/ko not_active Expired - Fee Related
- 1998-05-06 IL IL13251698A patent/IL132516A/xx not_active IP Right Cessation
- 1998-05-06 JP JP54843798A patent/JP3739802B2/ja not_active Expired - Fee Related
- 1998-05-06 PL PL336805A patent/PL193275B1/pl not_active IP Right Cessation
- 1998-05-06 EA EA199901012A patent/EA002908B1/ru not_active IP Right Cessation
- 1998-05-06 ES ES98920285T patent/ES2150404T3/es not_active Expired - Lifetime
- 1998-05-06 WO PCT/US1998/009229 patent/WO1998050035A1/en not_active Ceased
- 1998-05-06 CZ CZ0391199A patent/CZ298269B6/cs not_active IP Right Cessation
- 1998-05-06 AT AT98920285T patent/ATE228839T1/de active
- 1998-05-06 DK DK98920285T patent/DK1005342T3/da active
- 1998-05-06 TR TR1999/02733T patent/TR199902733T2/xx unknown
- 1998-05-06 PT PT02002887T patent/PT1222921E/pt unknown
- 1998-05-06 EA EA200100956A patent/EA002920B1/ru not_active IP Right Cessation
- 1998-05-06 CA CA002288003A patent/CA2288003C/en not_active Expired - Fee Related
- 1998-05-06 HU HU0003330A patent/HU229641B1/hu not_active IP Right Cessation
- 1998-05-06 DE DE69827417T patent/DE69827417T2/de not_active Expired - Lifetime
- 1998-05-06 CN CNB988049007A patent/CN1158074C/zh not_active Expired - Fee Related
- 1998-05-06 RO RO99-01166A patent/RO120605B1/ro unknown
- 1998-05-06 SI SI9820037A patent/SI20149B/sl not_active IP Right Cessation
- 1998-05-06 BR BR9808722-3A patent/BR9808722A/pt not_active IP Right Cessation
- 1998-05-06 ES ES02002887T patent/ES2232687T3/es not_active Expired - Lifetime
- 1998-05-06 CA CA002418634A patent/CA2418634C/en not_active Expired - Fee Related
- 1998-05-06 NZ NZ500149A patent/NZ500149A/en not_active IP Right Cessation
- 1998-05-06 AT AT02002887T patent/ATE281166T1/de active
- 1998-05-06 IL IL15579998A patent/IL155799A/en not_active IP Right Cessation
- 1998-05-06 CN CNB2004100459536A patent/CN100515420C/zh not_active Expired - Fee Related
- 1998-05-06 AU AU72895/98A patent/AU740022B2/en not_active Ceased
- 1998-05-06 ME MEP-2008-877A patent/ME00530B/me unknown
- 1998-05-06 GE GEAP19985109A patent/GEP20032970B/en unknown
- 1998-06-05 UA UA99126626A patent/UA57079C2/uk unknown
- 1998-12-06 BG BG109365A patent/BG109365A/en unknown
1999
- 1999-10-19 IS IS5223A patent/IS2087B/is unknown
- 1999-10-29 OA OA9900239A patent/OA11169A/en unknown
- 1999-11-04 NO NO19995406A patent/NO313983B1/no not_active IP Right Cessation
- 1999-12-01 LV LVP-99-170A patent/LV12492B/en unknown
- 1999-12-06 BG BG103958A patent/BG64973B1/bg unknown
2002
- 2002-04-18 NO NO20021832A patent/NO335781B1/no not_active IP Right Cessation
2003
- 2003-04-04 UA UA2003042974A patent/UA74388C2/uk unknown
2006
- 2006-12-14 AR ARP060105534A patent/AR057242A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
AP9901675A0 (en)	1999-12-31
CA2418634C (en)	2004-10-26
DE69809928D1 (de)	2003-01-16
ME00530B (me)	2011-10-10
BG64973B1 (bg)	2006-11-30
EP1005342B1 (en)	2002-12-04
NO20021832L (no)	2000-01-04
JP2001503067A (ja)	2001-03-06
CN1552322A (zh)	2004-12-08
KR20040004544A (ko)	2004-01-13
CN1255060A (zh)	2000-05-31
ES2232687T3 (es)	2005-06-01
PL193275B1 (pl)	2007-01-31
SK283946B6 (sk)	2004-05-04
NO995406L (no)	2000-01-04
ES2150404T3 (es)	2003-07-01
CZ391199A3 (cs)	2000-07-12
LV12492B (en)	2001-01-20
ATE281166T1 (de)	2004-11-15
HUP0003330A2 (hu)	2001-05-28
NO313983B1 (no)	2003-01-13
KR20010020322A (ko)	2001-03-15
NO995406D0 (no)	1999-11-04
EP1222921B1 (en)	2004-11-03
DK1005342T3 (da)	2003-03-24
BR9808722A (pt)	2000-07-11
CA2418634A1 (en)	1998-11-12
BG109365A (en)	2006-08-31
DE69827417D1 (de)	2004-12-09
DE69809928T2 (de)	2003-04-24
DK1222921T3 (da)	2005-03-07
SK283947B6 (sk)	2004-05-04
NO335781B1 (no)	2015-02-16
UA74388C2 (uk)	2005-12-15
CZ298269B6 (cs)	2007-08-08
EA002908B1 (ru)	2002-10-31
EA002920B1 (ru)	2002-10-31
WO1998050035A1 (en)	1998-11-12
IL155799A0 (en)	2003-12-23
EA200100956A1 (ru)	2002-02-28
EP1222921A1 (en)	2002-07-17
NZ500149A (en)	2001-11-30
HU229641B1 (en)	2014-03-28
IL155799A (en)	2004-08-31
CZ298270B6 (cs)	2007-08-08
KR100426657B1 (ko)	2004-04-13
SI20149A (sl)	2000-08-31
NO20021832D0 (no)	2002-04-18
DE69827417T2 (de)	2005-10-27
AU7289598A (en)	1998-11-27
CN100515420C (zh)	2009-07-22
SK151199A3 (en)	2000-07-11
ES2150404T1 (es)	2000-12-01
PT1005342E (pt)	2003-02-28
AP1103A (en)	2002-09-04
CN1158074C (zh)	2004-07-21
HUP0003330A3 (en)	2002-10-28
ATE228839T1 (de)	2002-12-15
CA2288003C (en)	2003-10-21
IS2087B (is)	2006-03-15
EA199901012A1 (ru)	2000-08-28
IL132516A0 (en)	2001-03-19
HK1025907A1 (en)	2000-12-01
BG103958A (en)	2000-07-31
AR057242A2 (es)	2007-11-21
SI20149B (en)	2001-08-31
EP1005342A1 (en)	2000-06-07
IL132516A (en)	2003-12-10
TR199902733T2 (xx)	2000-03-21
RO120605B1 (ro)	2006-05-30
LV12492A (en)	2000-06-20
UA57079C2 (uk)	2003-06-16
GEP20032970B (en)	2003-05-27
EP1005342A4 (en)	2001-02-07
KR100576646B1 (ko)	2006-05-08
PL336805A1 (en)	2000-07-17
EE04870B1 (et)	2007-08-15
PT1222921E (pt)	2005-02-28
JP3739802B2 (ja)	2006-01-25
NZ513881A (en)	2002-10-25
EE9900578A (et)	2000-08-15
AU740022B2 (en)	2001-10-25
OA11169A (en)	2003-04-25
CA2288003A1 (en)	1998-11-12

Publication	Publication Date	Title
DK0797431T3 (da)	2002-08-19	Aerosolformuleringer af peptider og proteiner
NO20021401D0 (no)	2002-03-20	Konazolinforbindelser og farmasöytiske preparater inneholdende slike forbindelser
DK0969836T3 (da)	2007-03-19	Lactosefri, ikke-vandsugende og vandfri farmaceutiske sammensætninger af descarbethoxyloratadin
IS5245A (is)	1999-11-11	Lyfjablanda úr ómeprasól
NO20014220D0 (no)	2001-08-31	<Kappa>-agonist-forbindelser og farmasöytiske preparater derav
NO981967L (no)	1998-06-30	Stabile fryset°rkede farmas°ytiske formuleringer
FI953515L (fi)	1996-01-21	Fluoksetiinin farmaseuttiset formulaatiot
NO993887L (no)	1999-08-12	Farmasöytiske formuleringer som innbefatter amoksycillin og clavulanat
NO20001914L (no)	2000-06-02	<alfa>-akryl-N-alkylnitroner og farmasøytiske blandinger som inneholder slike
DK1001813T3 (da)	2003-07-28	Farmaceutiske formuleringer indeholdende voriconazol
DK0983251T3 (da)	2004-09-27	Anti-inflammatorisk piperazinylbenzyltetrazolderivater og mellemprodukter derfor
LT99141A (lt)	2000-08-25	Tizoksanido ir nitazoksanido farmacinės kompozicijos
HUP9902655A3 (en)	2000-12-28	Pharmaceutical composition of hedgehog proteins and use thereof
IS2087B (is)	2006-03-15	Lyfjasamsetningar af tizoxaníði og nitazoxaníði
DK0994706T3 (da)	2006-03-06	Præparater til oral indgivelse af taxaner og anvendelse deraf
ID16781A (id)	1997-11-13	Formulasi-formulasi farmasi
HUP9900251A3 (en)	2001-01-29	Pharmaceutical compositions containing hedgehog proteins and use of former compositions
ZA995006B (en)	2000-02-07	Pharmaceutical composition of hedgehog proteins and use thereof.
BR9605220A (pt)	1998-07-21	Gonadotropinas e composiçao farmacêutica
SE9703737D0 (sv)	1997-10-14	Pharmaceutical composition and use
BR1101151A (pt)	2003-08-12	Compostos e composição farmacêutica
ZA99887B (en)	1999-08-04	Pharmaceutical composition of hedgehog proteins and use thereof.
NO974516D0 (no)	1997-09-30	Kreft og aids medisin: AXA