IS5339A - Alatrófloxasín samsetningar til notkunar utan meltingarvegar - Google Patents

Alatrófloxasín samsetningar til notkunar utan meltingarvegar

Info

Publication number
IS5339A
IS5339A IS5339A IS5339A IS5339A IS 5339 A IS5339 A IS 5339A IS 5339 A IS5339 A IS 5339A IS 5339 A IS5339 A IS 5339A IS 5339 A IS5339 A IS 5339A
Authority
IS
Iceland
Prior art keywords
alatrophloxacin
formulations
parenteral use
parenteral
alatrophloxacin formulations
Prior art date
Application number
IS5339A
Other languages
English (en)
Inventor
Mark Guinn Robert
Francis Lambert John
Sam Guhan Subramanian
Walter Walinsky Stanley
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of IS5339A publication Critical patent/IS5339A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06191Dipeptides containing heteroatoms different from O, S, or N
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IS5339A 1997-08-01 2000-01-14 Alatrófloxasín samsetningar til notkunar utan meltingarvegar IS5339A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5424697P 1997-08-01 1997-08-01
PCT/IB1998/001122 WO1999006430A1 (en) 1997-08-01 1998-07-23 Alatrofloxacin parenteral compositions

Publications (1)

Publication Number Publication Date
IS5339A true IS5339A (is) 2000-01-14

Family

ID=21989735

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5339A IS5339A (is) 1997-08-01 2000-01-14 Alatrófloxasín samsetningar til notkunar utan meltingarvegar

Country Status (40)

Country Link
US (1) US6194429B1 (is)
EP (1) EP1000086B1 (is)
JP (1) JP3463928B2 (is)
KR (1) KR20010022495A (is)
CN (1) CN1265671A (is)
AP (1) AP1031A (is)
AR (1) AR015417A1 (is)
AT (1) ATE259827T1 (is)
AU (1) AU734863B2 (is)
BG (1) BG104105A (is)
BR (1) BR9811580A (is)
CA (1) CA2296466C (is)
CO (1) CO4970688A1 (is)
DE (1) DE69821767T2 (is)
DK (1) DK1000086T3 (is)
DZ (1) DZ2576A1 (is)
EA (1) EA002120B1 (is)
ES (1) ES2214716T3 (is)
GT (1) GT199800112A (is)
HN (1) HN1998000106A (is)
HR (1) HRP980417B1 (is)
HU (1) HUP0004793A3 (is)
ID (1) ID24374A (is)
IL (1) IL134156A0 (is)
IS (1) IS5339A (is)
MA (1) MA24626A1 (is)
NO (1) NO20000485L (is)
NZ (1) NZ502249A (is)
OA (1) OA11281A (is)
PA (1) PA8456701A1 (is)
PE (1) PE103799A1 (is)
PL (1) PL338477A1 (is)
PT (1) PT1000086E (is)
SK (1) SK1012000A3 (is)
TN (1) TNSN98146A1 (is)
TW (1) TW538043B (is)
UY (1) UY25113A1 (is)
WO (1) WO1999006430A1 (is)
YU (1) YU2500A (is)
ZA (1) ZA986874B (is)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ECSP003699A (es) * 1999-10-08 2002-04-23 Smithkline Beecham Corp Inhibidores de fab i
EP1121933A1 (en) * 2000-02-02 2001-08-08 Pfizer Products Inc. Premixed alatrofloxacin injectable compositions
DE60230934D1 (de) 2001-04-06 2009-03-05 Affinium Pharm Inc Fab-i-inhibitoren
EP1575951B1 (en) 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
WO2004082586A2 (en) 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
CA2467321A1 (en) * 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
US8450307B2 (en) 2004-06-04 2013-05-28 Affinium Pharmaceuticals, Inc. Therapeutic agents, and methods of making and using the same
CA2632476A1 (en) * 2005-12-05 2007-06-14 Affinium Pharmaceuticals, Inc. Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
EP2687533B1 (en) 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors
WO2008098374A1 (en) * 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
KR101720885B1 (ko) 2012-06-19 2017-03-28 데비오팜 인터네셔날 에스 에이 (e)-n-메틸-n-((3-메틸벤조푸란-2-일)메틸)-3-(7-옥소-5,6,7,8-테트라히드로-1,8-나프티리딘-3-일)아크릴아미드의전구약물 유도체
RU2716164C2 (ru) * 2014-04-25 2020-03-06 Наурекс, Инк. Стабильные композиции нейроактивных пептидов
RS61312B1 (sr) 2016-02-26 2021-02-26 Debiopharm Int Sa Lek za lečenje infekcija dijabetskog stopala
CA3087898A1 (en) 2018-02-02 2019-08-08 Ripple Therapeutics Corporation Glass formulations comprising steroid dimers and uses thereof
WO2020154815A1 (en) 2019-02-01 2020-08-06 Ripple Therapeutics Corporation Crystalline forms of dexamethasone dimers and uses thereof
MY203711A (en) 2019-02-14 2024-07-15 Debiopharm Int Sa Afabicin formulation, method for making the same and uses thereof
JP7418475B2 (ja) 2019-06-14 2024-01-19 デバイオファーム インターナショナル エス.エー. バイオフィルムが関与する細菌感染症を治療するための医薬及びその使用
US12509469B2 (en) 2019-08-07 2025-12-30 Ripple Therapeutics Corporation Compositions and methods for the treatment of pain and dependence disorders
JP2023524494A (ja) 2020-05-01 2023-06-12 リップル セラピューティクス コーポレーション 眼障害を処置するためのヘテロ二量体組成物と方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3713672A1 (de) 1987-04-24 1988-11-17 Bayer Ag Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
US5256791A (en) 1992-03-02 1993-10-26 Pfizer Inc. Preparation of intermediates in the synthesis of quinoline antibiotics
RU2147303C1 (ru) 1994-01-18 2000-04-10 Пфайзер Инк. Промежуточные продукты и способ получения солей нафтиридонкарбоновой кислоты
TW420610B (en) 1994-04-07 2001-02-01 Pfizer A pharmaceutical composition for treating a H. pylori infection or gastric or duodenal ulcers
US5475116A (en) 1994-04-29 1995-12-12 Pfizer Inc. Aza bicyclo[3,1,0]hexane intermediates useful in the synthesis of quinolones
CA2223404C (en) 1995-06-06 2001-01-16 Thomas A. Morris Novel crystal form of anhydrous 7-(¬1.alpha., 5.alpha., 6.alpha.|-6-amino-3-azabicyclo¬3.1.0|hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt
US5939550A (en) * 1995-06-15 1999-08-17 Pfizer Inc. Process for preparing derivatives of azabicyclo naphthyridine carboxylic acid comprising a dipeptide
IL122652A (en) * 1995-08-29 2000-01-31 Pfizer Polymorphs of the pro drug 6-n-(l-ala-l-ala)- trovafloxacin their preparation and pharmaceutical compositions containing them
PL325170A1 (en) 1995-08-29 1998-07-06 Pfizer Bipolar forms of throwaflocacin
GB9524466D0 (en) 1995-11-30 1996-01-31 Pfizer Ltd Process
JPH1087617A (ja) 1996-07-09 1998-04-07 Pfizer Inc キノリン系抗生物質の合成に有用な中間体の製法

Also Published As

Publication number Publication date
JP2001512133A (ja) 2001-08-21
PE103799A1 (es) 1999-10-25
HUP0004793A2 (hu) 2001-04-28
DE69821767T2 (de) 2005-01-13
PL338477A1 (en) 2000-11-06
TW538043B (en) 2003-06-21
KR20010022495A (ko) 2001-03-15
NO20000485L (no) 2000-03-27
TNSN98146A1 (fr) 2005-03-15
CA2296466A1 (en) 1999-02-11
PT1000086E (pt) 2004-05-31
AU8236898A (en) 1999-02-22
IL134156A0 (en) 2001-04-30
NZ502249A (en) 2001-11-30
EP1000086A1 (en) 2000-05-17
DE69821767D1 (de) 2004-03-25
BG104105A (bg) 2000-08-31
CA2296466C (en) 2003-04-15
SK1012000A3 (en) 2000-09-12
JP3463928B2 (ja) 2003-11-05
GT199800112A (es) 2000-01-15
DK1000086T3 (da) 2004-05-17
ID24374A (id) 2000-07-13
HN1998000106A (es) 1999-01-08
WO1999006430A1 (en) 1999-02-11
AU734863B2 (en) 2001-06-21
MA24626A1 (fr) 1999-04-01
CN1265671A (zh) 2000-09-06
YU2500A (sh) 2002-09-19
AP1031A (en) 2001-12-21
HRP980417A2 (en) 1999-08-31
EA002120B1 (ru) 2001-12-24
AR015417A1 (es) 2001-05-02
US6194429B1 (en) 2001-02-27
UY25113A1 (es) 2000-12-29
NO20000485D0 (no) 2000-01-31
CO4970688A1 (es) 2000-11-07
HRP980417B1 (en) 2002-10-31
ZA986874B (en) 2000-01-31
AP9801310A0 (en) 1998-09-30
HUP0004793A3 (en) 2001-10-29
ATE259827T1 (de) 2004-03-15
EP1000086B1 (en) 2004-02-18
ES2214716T3 (es) 2004-09-16
EA200000086A1 (ru) 2000-08-28
BR9811580A (pt) 2000-08-22
PA8456701A1 (es) 2000-05-24
OA11281A (en) 2002-11-19
DZ2576A1 (fr) 2003-02-22

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