IS5846A - GnRH gerendur, sem ekki eru peptíð og aðferðir ogmilliefni til framleiðslu þeirra - Google Patents

GnRH gerendur, sem ekki eru peptíð og aðferðir ogmilliefni til framleiðslu þeirra

Info

Publication number: IS5846A
Authority: IS; Iceland
Prior art keywords: gnrh; intermediates; peptides; production; methods
Prior art date: 1998-08-20

Application number

IS5846A

Other languages

English (en)

Inventor

Brian Anderson Mark

N. Vazir Haresh

Robert Luthin David

Deguzman Paderes Genevieve

P. Pathak Ved

Christopher Christie Lance

Hong Yufeng

Valenzuela Tomkins Eileen

Li Haitao

Faust James

Original Assignee

Agouron Pharmaceuticals, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-20

Filing date

2001-02-16

Publication date

2001-02-16

2001-02-16 Application filed by Agouron Pharmaceuticals, Inc. filed Critical Agouron Pharmaceuticals, Inc.

2001-02-16 Publication of IS5846A publication Critical patent/IS5846A/is

Links

NMJREATYWWNIKX-UHFFFAOYSA-N GnRH Chemical compound C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CC(C)C)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 NMJREATYWWNIKX-UHFFFAOYSA-N 0.000 title 1
101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IS5846A 1998-08-20 2001-02-16 GnRH gerendur, sem ekki eru peptíð og aðferðir ogmilliefni til framleiðslu þeirra IS5846A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US9752098P	1998-08-20	1998-08-20
PCT/US1999/018790 WO2000020358A2 (en)	1998-08-20	1999-08-20	NON-PEPTIDE GnRH AGENTS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION

Publications (1)

Publication Number	Publication Date
IS5846A true IS5846A (is)	2001-02-16

Family

ID=22263796

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5846A IS5846A (is)	1998-08-20	2001-02-16	GnRH gerendur, sem ekki eru peptíð og aðferðir ogmilliefni til framleiðslu þeirra

Country Status (33)

Country	Link
EP (1)	EP1105120B1 (is)
JP (1)	JP2002535244A (is)
KR (1)	KR20010085402A (is)
CN (1)	CN1379666A (is)
AP (1)	AP2001002053A0 (is)
AT (1)	ATE291423T1 (is)
AU (1)	AU759310B2 (is)
BG (1)	BG105362A (is)
BR (1)	BR9913374A (is)
CA (1)	CA2341346A1 (is)
CZ (1)	CZ2001523A3 (is)
DE (1)	DE69924387D1 (is)
EA (1)	EA200100255A1 (is)
EE (1)	EE200100102A (is)
ES (1)	ES2237966T3 (is)
GE (1)	GEP20043315B (is)
HR (1)	HRP20010206A2 (is)
HU (1)	HUP0103622A3 (is)
ID (1)	ID29244A (is)
IL (1)	IL141396A0 (is)
IS (1)	IS5846A (is)
LT (1)	LT4904B (is)
LV (1)	LV12732B (is)
NO (1)	NO20010309L (is)
NZ (1)	NZ509252A (is)
OA (1)	OA11599A (is)
PL (1)	PL356984A1 (is)
SI (1)	SI20746A (is)
SK (1)	SK2262001A3 (is)
TR (1)	TR200100631T2 (is)
WO (1)	WO2000020358A2 (is)
YU (1)	YU13701A (is)
ZA (1)	ZA200100831B (is)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69333894D1 (de) *	1992-04-22	2005-12-01	Ligand Pharm Inc	Verbindungen mit Retinoid x rezeptorselektivität
IL145401A0 (en) *	1999-03-24	2002-06-30	Anormed Inc	Chemokine receptor binding heterocyclic compounds
AR024158A1 (es) *	1999-06-01	2002-09-04	Smithkline Beecham Corp	Compuestos antibacterianos
TWI243164B (en)	2001-02-13	2005-11-11	Aventis Pharma Gmbh	Acylated indanyl amines and their use as pharmaceuticals
EP1401427A4 (en) *	2001-06-06	2004-12-01	Agouron Pharma	NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF, PROCESSES FOR THE PREPARATION THEREOF
EP2363396A1 (en) *	2001-06-11	2011-09-07	Virochem Pharma Inc.	Thiophene derivatives as antiviral agents for flavivirus infection
EP1434579B1 (en)	2001-10-09	2011-06-08	Amgen Inc.	Imidazole derivatives as antiinflammatory agents
GB0126292D0 (en) *	2001-11-01	2002-01-02	Smithkline Beecham Plc	Compounds
JP2005170790A (ja) *	2002-01-09	2005-06-30	Ajinomoto Co Inc	Ｎ−アルキルスルフォニル置換アミド誘導体
US6521395B1 (en) *	2002-01-30	2003-02-18	Eastman Kodak Company	Infrared couplers for incorporating and recovering metadata
WO2003068769A1 (en) *	2002-02-12	2003-08-21	Pfizer Inc.	Non-peptide compounds affecting the action of gonadotropin-releasing hormone (gnrh)
TW200304820A (en) *	2002-03-25	2003-10-16	Avanir Pharmaceuticals	Use of benzimidazole analogs in the treatment of cell proliferation
JP2005538064A (ja)	2002-06-13	2005-12-15	ファイザー・インク	非ペプチドＧｎＲＨ剤、医薬組成物、およびそれらの使用方法
EP1562611B1 (en) *	2002-11-20	2006-08-02	Paradigm Therapeutics Ltd.	Heterocyclic silicon compounds and their use in the treatment of diseases or conditions associated with gnrh (gonadotropin-releasing hormone)
ZA200507112B (en) *	2003-03-31	2007-03-28	Taisho Pharmaceutical Co Ltd	Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof
US20050197350A1 (en) *	2003-03-31	2005-09-08	Taisho Pharmaceutical Co., Ltd.	Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof
US7427683B2 (en) *	2003-04-25	2008-09-23	Ortho-Mcneil Pharmaceutical, Inc.	c-fms kinase inhibitors
MXPA05011503A (es) *	2003-04-25	2006-05-31	Johnson & Johnson	Inhibidores de la c-fms cinasa.
US20050004133A1 (en) *	2003-06-05	2005-01-06	Makings Lewis R.	Modulators of VR1 receptor
AU2004255913B2 (en) *	2003-07-09	2007-10-11	Takeda Pharmaceutical Company Limited	Organosilicon compounds and their use
RU2303594C2 (ru) *	2003-07-09	2007-07-27	Пэредайм Терапьютикс Лтд.	Кремнийорганические соединения и их применение
AU2004255912B2 (en) *	2003-07-10	2008-05-01	Paradigm Therapeutics Ltd.	Silicon compounds and their use
WO2005039564A1 (en) *	2003-10-02	2005-05-06	Vertex Pharmaceuticals Incorporated	Phthalimide compounds useful as protein kinase inhibitors
US20090291915A1 (en) *	2004-12-17	2009-11-26	Graham Andrew Showell	Silicon Compounds and Their Use
JP5030947B2 (ja)	2005-05-13	2012-09-19	ヴァイロケム・ファーマ・インコーポレーテッド	フラビウイルス感染の治療及び予防のための化合物及び方法
US8193206B2 (en)	2005-06-14	2012-06-05	Taigen Biotechnology Co., Ltd.	Pyrimidine compounds
EA015890B1 (ru)	2005-06-14	2011-12-30	Тайджен Байотекнолоджи Ко. Лтд.	Производные пиримидина
WO2007000582A1 (en) *	2005-06-28	2007-01-04	Takeda Cambridge Limited	Heterocyclic non-peptide gnrh antagonists
US7345178B2 (en) *	2005-08-04	2008-03-18	Sirtris Pharmaceuticals, Inc.	Sirtuin modulating compounds
US8008481B2 (en)	2006-03-31	2011-08-30	Ericsson Anna M	Indazole compounds
US20080070987A1 (en) *	2006-05-12	2008-03-20	Francesc Yraola Font	Meta-xylylenediamine vanadate salts
TW200916472A (en)	2007-06-20	2009-04-16	Sirtris Pharmaceuticals Inc	Sirtuin modulating compounds
CA2701946A1 (en) *	2007-10-11	2009-04-16	Vertex Pharmaceuticals Incorporated	Heteroaryl amides useful as inhibitors of voltage-gated sodium channels
JPWO2009057199A1 (ja)	2007-10-31	2011-03-10	財団法人乙卯研究所	レチノイドプロドラッグ化合物
AU2008355098B2 (en)	2008-04-21	2012-11-15	Gpcr Therapeutics, Inc	Heterocyclic compounds
UY31984A (es) *	2008-07-16	2010-02-26	Boehringer Ingelheim Int	DERIVADOS DE 1-(3,4-difluorobencil)-6-oxo-1,6-dihidropirimidin-5-carboxamidas N-sustituidas y de 2-(3,4-difluorobencil)-3-oxo-2,3-dihidro-1H-pirazol-4-carboxamidas N-sustituidas.
WO2010056847A2 (en)	2008-11-13	2010-05-20	Taigen Biotechnology Co., Ltd.	Lyophilization formulation
SG10201505997TA (en)	2010-08-05	2015-09-29	Amgen Inc	Benzimidazole And Azabenzimidazole Compounds That Inhibit Anaplastic Lymphoma Kinase
CN102050823A (zh) *	2010-10-27	2011-05-11	华东理工大学	新型光稳定剂-鸟嘌呤类似物的合成及表征
US9199918B2 (en) *	2011-02-15	2015-12-01	Georgetown University	Small molecule inhibitors of AGBL2
WO2012155199A1 (en)	2011-05-16	2012-11-22	Bionomics Limited	Amine derivatives as potassium channel blockers
WO2013014204A2 (en)	2011-07-26	2013-01-31	Sanofi	3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
EP2776411B1 (en) *	2011-11-07	2019-06-26	The University of Queensland	Modulators of c3a receptors
CN104869990B (zh) *	2012-10-17	2022-12-20	艾科耐特有限公司	用于治疗眼部新生血管形成的化合物
GB201300304D0 (en) *	2013-01-08	2013-02-20	Kalvista Pharmaceuticals Ltd	Benzylamine derivatives
WO2017070235A1 (en) *	2015-10-19	2017-04-27	Attenua, Inc.	Antitussive compositions and methods
WO2019043217A1 (en)	2017-09-04	2019-03-07	F. Hoffmann-La Roche Ag	DIHYDROBENZIMIDAZOLONES
ES2995214T3 (en)	2019-03-06	2025-02-07	C4 Therapeutics Inc	Heterocyclic compounds for medical treatment

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3499002A (en) *	1968-06-20	1970-03-03	Robins Co Inc A H	1-carbamoyl-3-aroylpyrrolidines
NL6913261A (is) *	1968-09-09	1970-03-11
US3932444A (en) *	1972-04-28	1976-01-13	E. I. Du Pont De Nemours & Co.	4-Imidazolylsulfonylimidazoles
US4013647A (en) *	1976-03-23	1977-03-22	American Home Products Corporation	Morpholine containing tetrazole-5-carboxamide derivatives
GB1491776A (en) *	1976-09-08	1977-11-16	Pfizer Ltd	Thiadiazoles
US4076718A (en) *	1977-01-21	1978-02-28	American Home Products Corporation	2,6-Pyridinediyl-bis-tetrazol-5-carboxamides
US5236928A (en) *	1991-03-19	1993-08-17	Merck & Co., Inc.	Imidazole derivatives bearing acidic functional groups at the 5-position, their compositions and methods of use as angiotensin II antagonists
EP0592512A1 (en)	1991-07-01	1994-04-20	University Technologies International Inc. (Uti)	NON-DESENSITIZING ANALOGS OF GnRH AND OTHER BIOLOGICALLY ACTIVE LIGANDS
CA2126976A1 (en) *	1991-12-31	1993-07-08	Hisashi Takasugi	Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
DE69628705T2 (de) *	1995-08-24	2004-05-13	Basf Ag	Isoxazole- und Isothiazole-5-carboxamid Derivate, deren Herstellung und deren Verwendung als Herbizide
WO1997021707A1 (en) *	1995-12-14	1997-06-19	Merck & Co., Inc.	Antagonists of gonadotropin releasing hormone
CA2254769A1 (en) *	1996-05-20	1997-11-27	Merck & Co., Inc.	Antagonists of gonadotropin releasing hormone
US5878393A (en) *	1996-09-09	1999-03-02	Matsushita Electric Industrial Co., Ltd.	High quality concatenative reading system

1999
- 1999-08-20 AU AU24709/00A patent/AU759310B2/en not_active Ceased
- 1999-08-20 PL PL99356984A patent/PL356984A1/xx unknown
- 1999-08-20 NZ NZ509252A patent/NZ509252A/en unknown
- 1999-08-20 EA EA200100255A patent/EA200100255A1/ru unknown
- 1999-08-20 OA OA1200100043A patent/OA11599A/en unknown
- 1999-08-20 SK SK226-2001A patent/SK2262001A3/sk unknown
- 1999-08-20 CZ CZ2001523A patent/CZ2001523A3/cs unknown
- 1999-08-20 AP APAP/P/2001/002053A patent/AP2001002053A0/en unknown
- 1999-08-20 HR HR20010206A patent/HRP20010206A2/hr not_active Application Discontinuation
- 1999-08-20 DE DE69924387T patent/DE69924387D1/de not_active Expired - Fee Related
- 1999-08-20 JP JP2000574479A patent/JP2002535244A/ja active Pending
- 1999-08-20 AT AT99968010T patent/ATE291423T1/de not_active IP Right Cessation
- 1999-08-20 WO PCT/US1999/018790 patent/WO2000020358A2/en not_active Ceased
- 1999-08-20 IL IL14139699A patent/IL141396A0/xx unknown
- 1999-08-20 HU HU0103622A patent/HUP0103622A3/hu unknown
- 1999-08-20 CN CN99812285A patent/CN1379666A/zh active Pending
- 1999-08-20 CA CA002341346A patent/CA2341346A1/en not_active Abandoned
- 1999-08-20 TR TR2001/00631T patent/TR200100631T2/xx unknown
- 1999-08-20 BR BR9913374-1A patent/BR9913374A/pt not_active IP Right Cessation
- 1999-08-20 YU YU13701A patent/YU13701A/sh unknown
- 1999-08-20 SI SI9920076A patent/SI20746A/sl not_active IP Right Cessation
- 1999-08-20 EP EP99968010A patent/EP1105120B1/en not_active Expired - Lifetime
- 1999-08-20 ID IDW20010406A patent/ID29244A/id unknown
- 1999-08-20 KR KR1020017002021A patent/KR20010085402A/ko not_active Ceased
- 1999-08-20 EE EEP200100102A patent/EE200100102A/xx unknown
- 1999-08-20 ES ES99968010T patent/ES2237966T3/es not_active Expired - Lifetime
- 1999-08-20 GE GE4368A patent/GEP20043315B/en unknown
2001
- 2001-01-19 NO NO20010309A patent/NO20010309L/no not_active Application Discontinuation
- 2001-01-30 ZA ZA200100831A patent/ZA200100831B/en unknown
- 2001-02-16 IS IS5846A patent/IS5846A/is unknown
- 2001-03-16 LV LVP-01-45A patent/LV12732B/en unknown
- 2001-03-19 LT LT2001024A patent/LT4904B/lt unknown
- 2001-03-19 BG BG105362A patent/BG105362A/xx unknown

Also Published As

Publication number	Publication date
EA200100255A1 (ru)	2002-02-28
OA11599A (en)	2004-08-23
TR200100631T2 (tr)	2002-08-21
KR20010085402A (ko)	2001-09-07
NO20010309L (no)	2001-04-11
GEP20043315B (en)	2004-02-10
SI20746A (sl)	2002-06-30
AU759310B2 (en)	2003-04-10
ZA200100831B (en)	2002-08-22
SK2262001A3 (en)	2002-12-03
BG105362A (en)	2001-12-31
ID29244A (id)	2001-08-16
DE69924387D1 (de)	2005-04-28
WO2000020358A3 (en)	2000-11-16
HUP0103622A3 (en)	2003-01-28
ES2237966T3 (es)	2005-08-01
HUP0103622A2 (hu)	2002-04-29
EP1105120A4 (en)	2001-12-19
LV12732A (en)	2001-10-20
AP2001002053A0 (en)	2001-03-31
HRP20010206A2 (en)	2004-02-29
EP1105120A2 (en)	2001-06-13
WO2000020358A2 (en)	2000-04-13
LV12732B (en)	2002-03-20
LT4904B (lt)	2002-04-25
JP2002535244A (ja)	2002-10-22
WO2000020358B1 (en)	2001-01-04
IL141396A0 (en)	2002-03-10
PL356984A1 (en)	2004-07-12
NZ509252A (en)	2004-05-28
ATE291423T1 (de)	2005-04-15
CA2341346A1 (en)	2000-04-13
AU2470900A (en)	2000-04-26
EP1105120B1 (en)	2005-03-23
NO20010309D0 (no)	2001-01-19
YU13701A (sh)	2005-06-10
BR9913374A (pt)	2001-05-15
LT2001024A (en)	2001-11-26
EE200100102A (et)	2002-06-17
CN1379666A (zh)	2002-11-13
CZ2001523A3 (cs)	2002-05-15

Publication	Publication Date	Title
CY2019038I1 (el)	2020-05-29	Μεθοδοι για την κινητοποιηση κυτταρων προγεννητορων/βλαστοκυτταρων
MXPA03008608A (es)	2003-12-08	Revestimiento estructural aislado y metodo relacionado de revestimiento.
DE69907954D1 (de)	2003-06-18	Gasverdichter
NO20000866D0 (no)	2000-02-22	Innvendige isolerte, korrosjonsmotstandsdyktige rørledninger
DK1133586T3 (da)	2002-10-14	Højtrykselektrolysatormodul
AU2003302224A8 (en)	2004-06-18	Aerosol sampling system
AU2003299290A8 (en)	2004-06-18	Exhaust gas system
MXPA03006846A (es)	2003-11-13	Planta de recuperacion de dioxido de carbono.
DE69924387D1 (de)	2005-04-28	Nicht-peptidische gnrh agentia, verfahren und zwischenverbindungen zur ihren herstellung
MXPA02012644A (es)	2003-09-22	Metodo de planeacion de produccion y sistema para planeacion de produccion.
ZA200302548B (en)	2003-10-08	Gas recovery process.
AU2002230094A1 (en)	2002-09-04	Gas insulated switchgear
DE69937009D1 (de)	2007-10-11	Gasisolierte schaltanlage
GB0025088D0 (en)	2000-11-29	Stem cells
DE50009931D1 (de)	2005-05-04	Gaserzeugungssystem
NO993463D0 (no)	1999-07-14	Stålproduksjonsmetode
AU2001226639A1 (en)	2001-07-24	Gas analyser
AU2003256417A8 (en)	2004-02-25	Transposon-based transformation system
GB0106087D0 (en)	2001-05-02	Gas sampler
DE59914964D1 (de)	2009-04-02	Druckgasisolierte Schaltanlage
ATA33698A (de)	2005-04-15	Gasventil
IT247344Y1 (it)	2002-07-09	Rubinetto per gas valvolato.
GB0015699D0 (en)	2000-08-16	Assessment method
GB0110775D0 (en)	2001-06-27	Electrochemical gas sensors
FI20001947A0 (fi)	2000-09-05	Ionikaasu menetelmä