IS5898A - 5HT1 viðtaka gerandefni og metóklópramíð til meðhöndlunar á mígreni - Google Patents
5HT1 viðtaka gerandefni og metóklópramíð til meðhöndlunar á mígreniInfo
- Publication number
- IS5898A IS5898A IS5898A IS5898A IS5898A IS 5898 A IS5898 A IS 5898A IS 5898 A IS5898 A IS 5898A IS 5898 A IS5898 A IS 5898A IS 5898 A IS5898 A IS 5898A
- Authority
- IS
- Iceland
- Prior art keywords
- metoclopramide
- migraine
- treatment
- receptor agonists
- agonists
- Prior art date
Links
- 102000035038 5-HT1 receptors Human genes 0.000 title 1
- 108091005478 5-HT1 receptors Proteins 0.000 title 1
- 208000019695 Migraine disease Diseases 0.000 title 1
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 title 1
- 229960004503 metoclopramide Drugs 0.000 title 1
- 206010027599 migraine Diseases 0.000 title 1
- 239000000018 receptor agonist Substances 0.000 title 1
- 229940044601 receptor agonist Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10632898P | 1998-10-30 | 1998-10-30 | |
| PCT/IB1999/001694 WO2000025778A1 (en) | 1998-10-30 | 1999-10-18 | 5ht1 receptor agonists and metoclopramide for the treatment of migraine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS5898A true IS5898A (is) | 2001-03-16 |
Family
ID=22310818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS5898A IS5898A (is) | 1998-10-30 | 2001-03-16 | 5HT1 viðtaka gerandefni og metóklópramíð til meðhöndlunar á mígreni |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US6255334B1 (is) |
| EP (1) | EP1126840A1 (is) |
| JP (1) | JP2002528497A (is) |
| KR (1) | KR20010089363A (is) |
| CN (1) | CN1325304A (is) |
| AP (1) | AP2001002129A0 (is) |
| AR (1) | AR019246A1 (is) |
| AU (1) | AU5994799A (is) |
| BG (1) | BG105534A (is) |
| BR (1) | BR9914901A (is) |
| CA (1) | CA2348543A1 (is) |
| CO (1) | CO4950530A1 (is) |
| CZ (1) | CZ20011468A3 (is) |
| EA (1) | EA200100284A1 (is) |
| EE (1) | EE200100243A (is) |
| GT (1) | GT199900189A (is) |
| HK (1) | HK1040929A1 (is) |
| HR (1) | HRP20010298A2 (is) |
| HU (1) | HUP0104696A3 (is) |
| ID (1) | ID28291A (is) |
| IL (1) | IL141957A0 (is) |
| IS (1) | IS5898A (is) |
| MA (1) | MA26702A1 (is) |
| NO (1) | NO20012013D0 (is) |
| OA (1) | OA11669A (is) |
| PA (1) | PA8484801A1 (is) |
| PE (1) | PE20001284A1 (is) |
| PL (1) | PL347541A1 (is) |
| SK (1) | SK5522001A3 (is) |
| TN (1) | TNSN99203A1 (is) |
| TR (1) | TR200101174T2 (is) |
| TW (1) | TW524692B (is) |
| WO (1) | WO2000025778A1 (is) |
| ZA (1) | ZA200103322B (is) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0105131D0 (en) * | 2001-03-01 | 2001-04-18 | Pfizer Ltd | Compositions having improved bioavailability |
| US6579898B2 (en) * | 2001-03-01 | 2003-06-17 | Pfizer Inc. | Compositions having improved bioavailability |
| WO2002094242A1 (en) * | 2001-05-24 | 2002-11-28 | Alexza Molecular Delivery Corporation | Delivery of rizatriptan or zolmitriptan through an inhalation route |
| US7498019B2 (en) | 2001-05-24 | 2009-03-03 | Alexza Pharmaceuticals, Inc. | Delivery of compounds for the treatment of headache through an inhalation route |
| US20030051728A1 (en) | 2001-06-05 | 2003-03-20 | Lloyd Peter M. | Method and device for delivering a physiologically active compound |
| US7090830B2 (en) | 2001-05-24 | 2006-08-15 | Alexza Pharmaceuticals, Inc. | Drug condensation aerosols and kits |
| US7458374B2 (en) | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
| US7078016B2 (en) | 2001-11-21 | 2006-07-18 | Alexza Pharmaceuticals, Inc. | Delivery of caffeine through an inhalation route |
| US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
| JP2005503425A (ja) * | 2001-05-24 | 2005-02-03 | アレックザ モレキュラー デリヴァリー コーポレイション | 所定の吸入ルートによる薬剤エステルの送出 |
| US7585493B2 (en) | 2001-05-24 | 2009-09-08 | Alexza Pharmaceuticals, Inc. | Thin-film drug delivery article and method of use |
| US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
| ATE415155T1 (de) * | 2001-05-24 | 2008-12-15 | Alexza Pharmaceuticals Inc | Verabreichung von alprazolam, estazolam, midazolam oder triazolam durch inhalation |
| WO2003041693A1 (en) * | 2001-11-09 | 2003-05-22 | Alexza Molecular Delivery Corporation | Delivery of diazepam through an inhalation route |
| WO2003094900A1 (en) | 2002-05-13 | 2003-11-20 | Alexza Molecular Delivery Corporation | Delivery of drug amines through an inhalation route |
| US7550133B2 (en) | 2002-11-26 | 2009-06-23 | Alexza Pharmaceuticals, Inc. | Respiratory drug condensation aerosols and methods of making and using them |
| US20040105818A1 (en) | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
| JP2006514934A (ja) | 2002-11-26 | 2006-05-18 | アレックザ ファーマシューティカルズ， インコーポレイテッド | 疼痛治療用薬剤製造のためのロキサピンまたはアモキサピンの使用 |
| US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
| US20040234916A1 (en) | 2003-05-21 | 2004-11-25 | Alexza Molecular Delivery Corporation | Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same |
| US7540286B2 (en) | 2004-06-03 | 2009-06-02 | Alexza Pharmaceuticals, Inc. | Multiple dose condensation aerosol devices and methods of forming condensation aerosols |
| US20060002989A1 (en) * | 2004-06-10 | 2006-01-05 | Ahmed Salah U | Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same |
| US20050282879A1 (en) * | 2004-06-17 | 2005-12-22 | Foad Salehani | Methods and composition for treatment of migraine and symptoms thereof |
| EP1781360A1 (en) | 2004-08-12 | 2007-05-09 | Alexza Pharmaceuticals, Inc. | Aerosol drug delivery device incorporating percussively activated heat packages |
| ZA200709038B (en) * | 2005-04-13 | 2009-01-28 | Neuraxon Inc | Substituted indole compounds having nos inhibitory activity |
| CN101466709B (zh) * | 2006-04-13 | 2013-03-20 | 轴突公司 | 具有nos抑制活性的1,5和3,6-取代的吲哚化合物 |
| US20080139510A1 (en) * | 2006-12-07 | 2008-06-12 | Abe Rose | Treatment of migraine headaches with sublingual amino acids |
| WO2008112661A2 (en) | 2007-03-09 | 2008-09-18 | Alexza Pharmaceuticals, Inc. | Heating unit for use in a drug delivery device |
| EP2219449A4 (en) * | 2007-11-16 | 2010-10-27 | Univ Arizona State | METHOD FOR THE TREATMENT OF EXPOSURE TO DAMAGING |
| WO2009062318A1 (en) * | 2007-11-16 | 2009-05-22 | Neuraxon, Inc. | 3,5-substituted indole compounds having nos and norepinephrine reuptake inhibitory activity |
| EA201000808A1 (ru) * | 2007-11-16 | 2011-04-29 | Ньюраксон, Инк. | Индольные соединения и способы лечения висцеральной боли |
| AU2013202680C1 (en) * | 2008-04-28 | 2016-06-23 | Zogenix, Inc. | Novel formulations for treatment of migraine |
| US12214118B2 (en) | 2018-02-02 | 2025-02-04 | Alexza Pharmaceuticals, Inc. | Electrical condensation aerosol device |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698571A (en) * | 1994-10-05 | 1997-12-16 | Eli Lilly And Company | 5-HT1F mediated inhibition of neurogenic meningeal extravasation: a method for the treatment of migraine |
| WO1998002186A1 (en) * | 1996-07-11 | 1998-01-22 | Farmarc Nederland B.V. | Inclusion complex containing indole selective serotonin agonist |
| GB9709739D0 (en) | 1997-05-14 | 1997-07-02 | Merck Sharp & Dohme | Pharmaceutical formulation |
-
1999
- 1999-09-01 US US09/387,990 patent/US6255334B1/en not_active Expired - Fee Related
- 1999-10-18 WO PCT/IB1999/001694 patent/WO2000025778A1/en not_active Ceased
- 1999-10-18 EE EEP200100243A patent/EE200100243A/xx unknown
- 1999-10-18 BR BR9914901-0A patent/BR9914901A/pt not_active IP Right Cessation
- 1999-10-18 OA OA1200100100A patent/OA11669A/en unknown
- 1999-10-18 AP APAP/P/2001/002129A patent/AP2001002129A0/en unknown
- 1999-10-18 HK HK02102736.3A patent/HK1040929A1/zh unknown
- 1999-10-18 CZ CZ20011468A patent/CZ20011468A3/cs unknown
- 1999-10-18 CA CA002348543A patent/CA2348543A1/en not_active Abandoned
- 1999-10-18 IL IL14195799A patent/IL141957A0/xx unknown
- 1999-10-18 HR HR20010298A patent/HRP20010298A2/hr not_active Application Discontinuation
- 1999-10-18 AU AU59947/99A patent/AU5994799A/en not_active Abandoned
- 1999-10-18 JP JP2000579219A patent/JP2002528497A/ja active Pending
- 1999-10-18 HU HU0104696A patent/HUP0104696A3/hu unknown
- 1999-10-18 EA EA200100284A patent/EA200100284A1/ru unknown
- 1999-10-18 ID IDW00200100930A patent/ID28291A/id unknown
- 1999-10-18 SK SK552-2001A patent/SK5522001A3/sk unknown
- 1999-10-18 KR KR1020017005271A patent/KR20010089363A/ko not_active Ceased
- 1999-10-18 TR TR2001/01174T patent/TR200101174T2/xx unknown
- 1999-10-18 CN CN99812756A patent/CN1325304A/zh active Pending
- 1999-10-18 EP EP99971318A patent/EP1126840A1/en not_active Withdrawn
- 1999-10-18 PL PL99347541A patent/PL347541A1/xx not_active Application Discontinuation
- 1999-10-27 PA PA19998484801A patent/PA8484801A1/es unknown
- 1999-10-27 TN TNTNSN99203A patent/TNSN99203A1/fr unknown
- 1999-10-27 MA MA25827A patent/MA26702A1/fr unknown
- 1999-10-27 TW TW088118594A patent/TW524692B/zh active
- 1999-10-28 AR ARP990105447A patent/AR019246A1/es not_active Application Discontinuation
- 1999-10-29 PE PE1999001083A patent/PE20001284A1/es not_active Application Discontinuation
- 1999-10-29 CO CO99068659A patent/CO4950530A1/es unknown
- 1999-10-29 GT GT199900189A patent/GT199900189A/es unknown
-
2001
- 2001-03-16 IS IS5898A patent/IS5898A/is unknown
- 2001-04-19 US US09/838,440 patent/US20010020036A1/en not_active Abandoned
- 2001-04-24 ZA ZA200103322A patent/ZA200103322B/en unknown
- 2001-04-24 NO NO20012013A patent/NO20012013D0/no not_active Application Discontinuation
- 2001-05-22 BG BG105534A patent/BG105534A/xx unknown
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