IS6438A - Nýjar asabísýklóoktanafleiður sem eru gagnlegar við meðhöndlun á hjartsláttartruflunum - Google Patents

Nýjar asabísýklóoktanafleiður sem eru gagnlegar við meðhöndlun á hjartsláttartruflunum

Info

Publication number
IS6438A
IS6438A IS6438A IS6438A IS6438A IS 6438 A IS6438 A IS 6438A IS 6438 A IS6438 A IS 6438A IS 6438 A IS6438 A IS 6438A IS 6438 A IS6438 A IS 6438A
Authority
IS
Iceland
Prior art keywords
asabicyclooctane
arrhythmias
treatment
new
derivatives useful
Prior art date
Application number
IS6438A
Other languages
English (en)
Inventor
Björsne Magnus
Pontén Fritiof
Strandlund Gert
Svensson Peder
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS6438A publication Critical patent/IS6438A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/24—Camphidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IS6438A 1999-12-23 2002-06-20 Nýjar asabísýklóoktanafleiður sem eru gagnlegar við meðhöndlun á hjartsláttartruflunum IS6438A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9904765A SE9904765D0 (sv) 1999-12-23 1999-12-23 Pharmaceutically-useful compounds
PCT/SE2000/002604 WO2001047893A1 (en) 1999-12-23 2000-12-19 New azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
IS6438A true IS6438A (is) 2002-06-20

Family

ID=20418291

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6438A IS6438A (is) 1999-12-23 2002-06-20 Nýjar asabísýklóoktanafleiður sem eru gagnlegar við meðhöndlun á hjartsláttartruflunum

Country Status (26)

Country Link
US (1) US6559162B2 (is)
EP (1) EP1244631A1 (is)
JP (1) JP2003519128A (is)
KR (1) KR20020063261A (is)
CN (1) CN1229350C (is)
AR (1) AR026925A1 (is)
AU (1) AU777069B2 (is)
BR (1) BR0016678A (is)
CA (1) CA2394097A1 (is)
CO (1) CO5261611A1 (is)
CZ (1) CZ20022174A3 (is)
EE (1) EE200200305A (is)
HU (1) HUP0301030A3 (is)
IL (1) IL150212A0 (is)
IS (1) IS6438A (is)
MX (1) MXPA02006249A (is)
MY (1) MY133785A (is)
NO (1) NO20023038L (is)
NZ (1) NZ519497A (is)
PL (1) PL357098A1 (is)
RU (1) RU2262505C2 (is)
SE (1) SE9904765D0 (is)
SK (1) SK8912002A3 (is)
UA (1) UA75057C2 (is)
WO (1) WO2001047893A1 (is)
ZA (1) ZA200204310B (is)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
JP2003528076A (ja) * 2000-03-20 2003-09-24 メルク シャープ エンド ドーム リミテッド スルホンアミド置換架橋ビシクロアルキル誘導体
MXPA04000565A (es) * 2001-07-19 2005-06-17 Cv Therapeutics Inc Compuestos de piperazina sustituidos y su uso como inhibidores de oxidacion de acidos grasos.
US7001909B2 (en) * 2001-07-19 2006-02-21 Cv Therapeutics, Inc. Substituted heterocyclic compounds
EA200500173A1 (ru) 2002-07-08 2005-08-25 Рэнбакси Лабораториз Лимитед Производные 3,6-дизамещенного азабицикло[3.1.0]гексана в качестве антагонистов мускариновых рецепторов
US7056924B2 (en) * 2002-07-18 2006-06-06 Cv Therapeutics, Inc. Substituted heterocyclic compounds
US7488748B2 (en) * 2003-01-28 2009-02-10 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
EP1618091A1 (en) 2003-04-09 2006-01-25 Ranbaxy Laboratories, Ltd. Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
WO2004089900A1 (en) 2003-04-11 2004-10-21 Ranbaxy Laboratories Limited Azabicyclo derivatives as muscarinic receptor antagonists
CA2530376A1 (en) * 2003-06-23 2005-01-06 Cv Therapeutics, Inc. Urea derivatives of piperazines and piperidines as fatty acid oxidation inhibitors
WO2006035303A1 (en) * 2004-09-29 2006-04-06 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
JP4994772B2 (ja) * 2006-10-11 2012-08-08 日本曹達株式会社 ビスアミノールエーテル化合物を用いるピペリジン−4−オン誘導体の製造方法
JP4999061B2 (ja) * 2006-10-11 2012-08-15 日本曹達株式会社 ピペリジン−4−オン誘導体の製造方法
JP5694765B2 (ja) * 2007-05-17 2015-04-01 コーテックス ファーマシューティカルズ, インコーポレイテッド グルタミン酸作動性シナプス反応を増強するための二置換アミド
CN102311439B (zh) * 2010-07-02 2015-11-25 上海药明康德新药开发有限公司 1-取代-3,8-二氮杂双环[3.2.1]辛烷衍生物及制备方法
CN102452981B (zh) * 2010-11-03 2015-08-19 上海药明康德新药开发有限公司 1,3-二取代-3-氮杂双环[3.2.1]辛烷衍生物及制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
GB8516371D0 (en) * 1985-06-28 1985-07-31 Beecham Group Plc Compounds
PT88381B (pt) 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5070094A (en) * 1989-09-05 1991-12-03 G. D. Searle & Co. N-benzyltropaneamides
US5084572A (en) * 1989-11-13 1992-01-28 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo [3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
FR2707986B1 (fr) * 1993-07-22 1996-02-23 Smithkline Beecham Labo Pharma Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments.
JP3235913B2 (ja) 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
US5468858A (en) 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4402931A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
NZ326874A (en) 1996-03-29 2000-01-28 Pfizer 6-phenylpyridyl-2-amine derivatives
AU733454B2 (en) 1996-10-30 2001-05-17 Schering Corporation Piperazino derivatives as neurokinin antagonists
SE9704709D0 (sv) 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
TR200102911T2 (tr) 1999-04-09 2002-01-21 Astrazeneca Ab Adamantan türevleri.
SE9901875D0 (sv) 1999-05-25 1999-05-25 Astra Pharma Prod Novel compounds

Also Published As

Publication number Publication date
PL357098A1 (en) 2004-07-12
CZ20022174A3 (cs) 2002-09-11
AU2565901A (en) 2001-07-09
EP1244631A1 (en) 2002-10-02
SK8912002A3 (en) 2003-02-04
UA75057C2 (en) 2006-03-15
US6559162B2 (en) 2003-05-06
CO5261611A1 (es) 2003-03-31
ZA200204310B (en) 2003-08-29
NZ519497A (en) 2004-02-27
IL150212A0 (en) 2002-12-01
JP2003519128A (ja) 2003-06-17
MY133785A (en) 2007-11-30
NO20023038L (no) 2002-08-22
US20020137766A1 (en) 2002-09-26
KR20020063261A (ko) 2002-08-01
NO20023038D0 (no) 2002-06-21
HUP0301030A2 (hu) 2003-08-28
BR0016678A (pt) 2002-10-15
RU2002114821A (ru) 2004-01-20
WO2001047893A1 (en) 2001-07-05
AU777069B2 (en) 2004-09-30
CA2394097A1 (en) 2001-07-05
SE9904765D0 (sv) 1999-12-23
HUP0301030A3 (en) 2007-03-28
RU2262505C2 (ru) 2005-10-20
CN1434802A (zh) 2003-08-06
AR026925A1 (es) 2003-03-05
CN1229350C (zh) 2005-11-30
MXPA02006249A (es) 2004-09-06
EE200200305A (et) 2003-06-16

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