IS7546A - Indól, azaindól og skyld heterósýklísk 4-alkenýl píperidín amíð - Google Patents

Indól, azaindól og skyld heterósýklísk 4-alkenýl píperidín amíð

Info

Publication number: IS7546A
Authority: IS; Iceland
Prior art keywords: azaindole; indole; related heterocyclic; piperidine amide; alkenyl piperidine
Prior art date: 2002-05-28

Application number

IS7546A

Other languages

English (en)

Other versions

IS2945B (is

Inventor

Wang Tao

F. Kadow John

A. Meanwell Nicholas

Yeung Kap-Sun

Zhang Zhongxing

Yin Zhiwei

Qiu Zhilei

H. Deon Daniel

A. James Clint

H. Ruediger Edward

Bachand Carol

Original Assignee

Bristol-Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-28

Filing date

2004-11-22

Publication date

2004-11-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32312411&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS7546(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-11-22 Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company

2004-11-22 Publication of IS7546A publication Critical patent/IS7546A/is

2016-05-15 Publication of IS2945B publication Critical patent/IS2945B/is

Links

SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 2
BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical compound C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title 1
125000000623 heterocyclic group Chemical group 0.000 title 1
PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title 1
RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IS7546A 2002-05-28 2004-11-22 Indól, azaindól og skyld heterósýklísk 4-alkenýl píperidín amíð IS2945B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US38350902P	2002-05-28	2002-05-28
PCT/US2003/013324 WO2004043337A2 (en)	2002-05-28	2003-04-30	Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides

Publications (2)

Publication Number	Publication Date
IS7546A true IS7546A (is)	2004-11-22
IS2945B IS2945B (is)	2016-05-15

Family

ID=32312411

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7546A IS2945B (is)	2002-05-28	2004-11-22	Indól, azaindól og skyld heterósýklísk 4-alkenýl píperidín amíð

Country Status (31)

Country	Link
US (1)	US20040063744A1 (is)
EP (1)	EP1513832B1 (is)
JP (1)	JP4446889B2 (is)
KR (1)	KR101001811B1 (is)
CN (1)	CN100528866C (is)
AR (1)	AR040230A1 (is)
AU (1)	AU2003301958B2 (is)
BR (2)	BRPI0311541B1 (is)
CA (1)	CA2487542C (is)
CL (1)	CL2003001087A1 (is)
CO (1)	CO5631440A2 (is)
DK (1)	DK1513832T3 (is)
ES (1)	ES2460728T3 (is)
GE (1)	GEP20074152B (is)
HR (1)	HRP20041137B1 (is)
IL (1)	IL165200A (is)
IS (1)	IS2945B (is)
MX (1)	MXPA04011670A (is)
MY (1)	MY139058A (is)
NO (1)	NO329691B1 (is)
NZ (1)	NZ536661A (is)
PE (1)	PE20040526A1 (is)
PL (1)	PL216388B1 (is)
PT (1)	PT1513832E (is)
RS (1)	RS53021B (is)
RU (1)	RU2323934C2 (is)
SI (1)	SI1513832T1 (is)
TW (1)	TWI310381B (is)
UA (1)	UA79470C2 (is)
WO (1)	WO2004043337A2 (is)
ZA (1)	ZA200409504B (is)

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US6476034B2 (en) *	2000-02-22	2002-11-05	Bristol-Myers Squibb Company	Antiviral azaindole derivatives
US20040110785A1 (en) *	2001-02-02	2004-06-10	Tao Wang	Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
US20050075364A1 (en) *	2003-07-01	2005-04-07	Kap-Sun Yeung	Indole, azaindole and related heterocyclic N-substituted piperazine derivatives
US20050124623A1 (en)	2003-11-26	2005-06-09	Bender John A.	Diazaindole-dicarbonyl-piperazinyl antiviral agents
US7087610B2 (en) *	2004-06-03	2006-08-08	Bristol-Myers Squibb Company	Benzothiazole antiviral agents
DK1753764T3 (da)	2004-06-09	2009-02-16	Glaxo Group Ltd	Pyrrolopyridin-derivater
US20060100209A1 (en) *	2004-11-09	2006-05-11	Chong-Hui Gu	Formulations of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
US20060100432A1 (en) *	2004-11-09	2006-05-11	Matiskella John D	Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
US7601715B2 (en) *	2005-06-22	2009-10-13	Bristol-Myers Squibb Company	Process for preparing triazole substituted azaindoleoxoacetic piperazine derivatives and novel salt forms produced therein
BRPI0614272A2 (pt) *	2005-08-09	2011-03-22	Glaxo Group Ltd	derivados de imidazopiridinas como ligantes de receptores canabinóides
US7851476B2 (en) *	2005-12-14	2010-12-14	Bristol-Myers Squibb Company	Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine
US7807671B2 (en) *	2006-04-25	2010-10-05	Bristol-Myers Squibb Company	Diketo-piperazine and piperidine derivatives as antiviral agents
US7504399B2 (en) *	2006-06-08	2009-03-17	Bristol-Meyers Squibb Company	Piperazine enamines as antiviral agents
US7572810B2 (en) *	2006-06-08	2009-08-11	Bristol-Myers Squibb Company	Alkene piperidine derivatives as antiviral agents
KR20100017372A (ko) *	2007-05-25	2010-02-16	애보트 게엠베하 운트 콤파니 카게	향대사성 글루타메이트 수용체 2（ｍｇｌｕ2 수용체）의 포지티브 조절자로서의 헤테로사이클릭 화합물
WO2009011912A1 (en) *	2007-07-18	2009-01-22	Bristol-Myers Squibb Company	A composition for treating hiv comprising virus-like particles
JP5433691B2 (ja) *	2008-06-25	2014-03-05	ブリストル−マイヤーズスクイブカンパニー	Ｈｉｖ結合阻害剤としてのジケトピペリジン誘導体
EP2303876B1 (en) *	2008-06-25	2014-03-19	Bristol-Myers Squibb Company	Diketo azolopiperidines and azolopiperazines as anti-hiv agents
CN102143739B (zh) *	2008-09-04	2014-12-17	百时美施贵宝公司	用于最优化传递hiv附着抑制剂的稳定的药用组合物
WO2010099166A1 (en)	2009-02-27	2010-09-02	Siga Technologies, Inc.	Thienopyridine derivatives for the treatment and prevention of dengue virus infections
CN102428069B (zh)	2009-04-02	2014-04-02	盐野义制药株式会社	丙烯酰胺化合物及其用途
EP2308866A1 (de)	2009-10-09	2011-04-13	Bayer CropScience AG	Phenylpyri(mi)dinylpyrazole und ihre Verwendung als Fungizide
EP2601174B1 (en) *	2010-08-06	2014-11-26	Bristol-Myers Squibb Company	Substituted indole and azaindole oxoacetyl piperazinamide derivatives
US8912195B2 (en)	2010-12-02	2014-12-16	Bristol-Myers Squibb Company	Alkyl amides as HIV attachment inhibitors
WO2012142080A1 (en)	2011-04-12	2012-10-18	Bristol-Myers Squibb Company	Thioamide, amidoxime and amidrazone derivatives as hiv attachment inhibitors
EP2751119B1 (en)	2011-08-29	2016-11-23	VIIV Healthcare UK (No.5) Limited	Fused bicyclic diamine derivatives as hiv attachment inhibitors
WO2013033059A1 (en)	2011-08-29	2013-03-07	Bristol-Myers Squibb Company	Spiro bicyclic diamine derivatives as hiv attachment inhibitors
JP6114314B2 (ja) *	2012-02-08	2017-04-12	ブリストル−マイヤーズスクイブカンパニーＢｒｉｓｔｏｌ−ＭｙｅｒｓＳｑｕｉｂｂＣｏｍｐａｎｙ	Ｈｉｖ付着阻害剤であるピペラジンプロドラッグ化合物の製造方法
US9193725B2 (en)	2012-03-14	2015-11-24	Bristol-Meyers Squibb Company	Cyclic hydrazine derivatives as HIV attachment inhibitors
ES2616432T3 (es) *	2012-08-09	2017-06-13	VIIV Healthcare UK (No.5) Limited	Derivados de alquenos tricíclicos como inhibidores de la unión del VIH
WO2014025854A1 (en) *	2012-08-09	2014-02-13	Bristol-Myers Squibb Company	Piperidine amide derivatives as hiv attachment inhibitors
WO2017112576A1 (en) *	2015-12-21	2017-06-29	Dow Global Technologies Llc	Methods for external base-free suzuki couplings
CN108059611A (zh) *	2018-01-22	2018-05-22	济南舜景医药科技有限公司	一种用于治疗心率不齐药物中间体的合成方法
CN109053575A (zh) *	2018-08-24	2018-12-21	遵义医学院	3-环丙基-1-甲基-1h-吡唑-4-甲醛的制备工艺
JP7690493B2 (ja) *	2020-05-04	2025-06-10	大鵬薬品工業株式会社	Ｉａｐアンタゴニスト化合物及びその中間体、並びにそれを合成する方法
WO2022146920A1 (en) *	2020-12-28	2022-07-07	Celgene Corporation	Heterocyclic compounds and their use for parasitic diseases

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2003
- 2003-04-29 US US10/425,370 patent/US20040063744A1/en not_active Abandoned
- 2003-04-30 BR BRPI0311541-0A patent/BRPI0311541B1/pt unknown
- 2003-04-30 DK DK03811179.5T patent/DK1513832T3/da active
- 2003-04-30 CA CA2487542A patent/CA2487542C/en not_active Expired - Fee Related
- 2003-04-30 AU AU2003301958A patent/AU2003301958B2/en not_active Ceased
- 2003-04-30 RU RU2004138565/04A patent/RU2323934C2/ru not_active IP Right Cessation
- 2003-04-30 PT PT38111795T patent/PT1513832E/pt unknown
- 2003-04-30 GE GEAP8554A patent/GEP20074152B/en unknown
- 2003-04-30 SI SI200332346T patent/SI1513832T1/sl unknown
- 2003-04-30 KR KR1020047019219A patent/KR101001811B1/ko not_active Expired - Fee Related
- 2003-04-30 UA UA20041210893A patent/UA79470C2/uk unknown
- 2003-04-30 RS YU101304A patent/RS53021B/sr unknown
- 2003-04-30 HR HRP20041137AA patent/HRP20041137B1/hr not_active IP Right Cessation
- 2003-04-30 EP EP03811179.5A patent/EP1513832B1/en not_active Expired - Lifetime
- 2003-04-30 JP JP2004551400A patent/JP4446889B2/ja not_active Expired - Fee Related
- 2003-04-30 NZ NZ536661A patent/NZ536661A/en not_active IP Right Cessation
- 2003-04-30 BR BRPI0311541-0A patent/BR0311541A/pt not_active IP Right Cessation
- 2003-04-30 PL PL373603A patent/PL216388B1/pl unknown
- 2003-04-30 ES ES03811179.5T patent/ES2460728T3/es not_active Expired - Lifetime
- 2003-04-30 CN CNB038175657A patent/CN100528866C/zh not_active Expired - Fee Related
- 2003-04-30 MX MXPA04011670A patent/MXPA04011670A/es active IP Right Grant
- 2003-04-30 WO PCT/US2003/013324 patent/WO2004043337A2/en not_active Ceased
- 2003-05-22 TW TW092113891A patent/TWI310381B/zh not_active IP Right Cessation
- 2003-05-23 MY MYPI20031927A patent/MY139058A/en unknown
- 2003-05-28 PE PE2003000514A patent/PE20040526A1/es not_active Application Discontinuation
- 2003-05-28 AR ARP030101879A patent/AR040230A1/es not_active Application Discontinuation
- 2003-05-28 CL CL200301087A patent/CL2003001087A1/es unknown
2004
- 2004-11-15 IL IL165200A patent/IL165200A/en active IP Right Grant
- 2004-11-22 IS IS7546A patent/IS2945B/is unknown
- 2004-11-22 NO NO20045064A patent/NO329691B1/no not_active IP Right Cessation
- 2004-11-24 ZA ZA200409504A patent/ZA200409504B/en unknown
- 2004-11-26 CO CO04119328A patent/CO5631440A2/es active IP Right Grant

Also Published As

Publication number	Publication date
US20040063744A1 (en)	2004-04-01
PL216388B1 (pl)	2014-03-31
ES2460728T3 (es)	2014-05-14
CN100528866C (zh)	2009-08-19
CA2487542A1 (en)	2004-05-27
CL2003001087A1 (es)	2005-02-11
JP4446889B2 (ja)	2010-04-07
WO2004043337A2 (en)	2004-05-27
AR040230A1 (es)	2005-03-23
JP2006507326A (ja)	2006-03-02
CA2487542C (en)	2011-09-27
TW200406397A (en)	2004-05-01
CN1671697A (zh)	2005-09-21
MY139058A (en)	2009-08-28
ZA200409504B (en)	2006-05-31
NZ536661A (en)	2007-12-21
CO5631440A2 (es)	2006-04-28
KR101001811B1 (ko)	2010-12-15
WO2004043337A3 (en)	2004-11-11
UA79470C2 (en)	2007-06-25
BR0311541A (pt)	2006-06-06
EP1513832A4 (en)	2010-03-10
HRP20041137B1 (hr)	2014-11-21
PT1513832E (pt)	2014-05-22
HRP20041137A2 (en)	2005-06-30
TWI310381B (en)	2009-06-01
KR20050013558A (ko)	2005-02-04
IL165200A (en)	2011-01-31
DK1513832T3 (da)	2014-05-26
PL373603A1 (en)	2005-09-05
IL165200A0 (en)	2005-12-18
GEP20074152B (en)	2007-07-10
NO20045064L (no)	2005-02-23
EP1513832A2 (en)	2005-03-16
NO329691B1 (no)	2010-11-29
AU2003301958B2 (en)	2009-10-01
AU2003301958A1 (en)	2004-06-03
RU2323934C2 (ru)	2008-05-10
BRPI0311541B1 (pt)	2018-04-24
RU2004138565A (ru)	2005-07-20
RS53021B (sr)	2014-04-30
PE20040526A1 (es)	2004-08-28
SI1513832T1 (sl)	2014-04-30
IS2945B (is)	2016-05-15
RS101304A (sr)	2006-10-27
MXPA04011670A (es)	2005-03-07
EP1513832B1 (en)	2014-03-05

Publication	Publication Date	Title
IS2945B (is)	2016-05-15	Indól, azaindól og skyld heterósýklísk 4-alkenýl píperidín amíð
EP1474135A4 (en)	2006-01-18	INDOL, AZAINDOL AND RELATED HETEROCYCLIC PYRROLIDINE DERIVATIVES
DE60336314D1 (de)	2011-04-21	Substituierte indole
DK1515969T3 (da)	2010-12-13	Spiroindolinpiperidinderivater
ATE517888T1 (de)	2011-08-15	Indolylmaleimid-derivate
DK1537078T3 (da)	2010-08-02	Indoler med anti-diabetisk aktivitet
IS2599B (is)	2010-04-15	3-fenýlsúlfónýl-8-píperasín-1-ýl-kínólín og lyfjafræðilega viðurkenndar afleiður þess
IS2504B (is)	2009-04-15	Fosfónóoxýkínasólínafleiður og lyfjafræileg notkun þeirra
DE60301683D1 (de)	2005-11-03	Leseverstärker
ATE308543T1 (de)	2005-11-15	Piperidinderivate
DK1554250T3 (da)	2007-12-17	Hidtil ukendt lactamer og anvendelser deraf
ATE423117T1 (de)	2009-03-15	Heterocyclische 7-aminoalkylidenylchinolone und - naphthyridone
IS8040A (is)	2005-09-22	Arómatískt oxýfenýl og arómatískar súlfanýlfenýl afleiður
AU2003236512A8 (en)	2004-01-06	Indole, azaindole and related heterocyclic sulfonylureido piperazine derivatives
FI20020341A7 (fi)	2003-08-21	Turvasäilytyslaite
ATE361290T1 (de)	2007-05-15	1-(indol-3-yl)carbonyl piperazinderivate
DE60335283D1 (de)	2011-01-20	Bildaufnahmevorrichtung
IS7980A (is)	2005-08-12	Díarýlmetýlídenpíperidínafleiður, framleiðsla þeirra og notkun
DE60329232D1 (de)	2009-10-22	Aufzeichnungsvorrichtung
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ATE405560T1 (de)	2008-09-15	Indolderivaten
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