IS7833A - Efnasambönd með sameinaða heteróhringi - Google Patents

Efnasambönd með sameinaða heteróhringi

Info

Publication number
IS7833A
IS7833A IS7833A IS7833A IS7833A IS 7833 A IS7833 A IS 7833A IS 7833 A IS7833 A IS 7833A IS 7833 A IS7833 A IS 7833A IS 7833 A IS7833 A IS 7833A
Authority
IS
Iceland
Prior art keywords
heterocyclic compounds
combined
combined heterocyclic
compounds
heterocyclic
Prior art date
Application number
IS7833A
Other languages
English (en)
Inventor
Chen Xi
Chen Xiaoqi
Fan Pingchen
Jaen Juan
Li Leping
T. Mihalic Jeffrey
Original Assignee
Amgen Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc. filed Critical Amgen Inc.
Publication of IS7833A publication Critical patent/IS7833A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IS7833A 2002-11-06 2005-05-02 Efnasambönd með sameinaða heteróhringi IS7833A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42445602P 2002-11-06 2002-11-06
PCT/US2003/035543 WO2004043958A1 (en) 2002-11-06 2003-11-06 Fused heterocyclic compounds

Publications (1)

Publication Number Publication Date
IS7833A true IS7833A (is) 2005-05-02

Family

ID=32312811

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7833A IS7833A (is) 2002-11-06 2005-05-02 Efnasambönd með sameinaða heteróhringi

Country Status (16)

Country Link
US (2) US7253179B2 (is)
EP (1) EP1562943A1 (is)
JP (1) JP4547266B2 (is)
KR (1) KR20050103184A (is)
CN (2) CN1330651C (is)
AU (1) AU2003285160B2 (is)
BR (1) BR0316070A (is)
CA (1) CA2505372A1 (is)
EA (1) EA009421B1 (is)
IS (1) IS7833A (is)
MX (1) MXPA05004739A (is)
NO (1) NO20052655L (is)
NZ (1) NZ540328A (is)
PL (1) PL376659A1 (is)
WO (1) WO2004043958A1 (is)
ZA (1) ZA200503654B (is)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6809104B2 (en) * 2001-05-04 2004-10-26 Tularik Inc. Fused heterocyclic compounds
US20070135425A1 (en) * 2001-05-04 2007-06-14 Amgen Inc. Fused heterocyclic compounds
WO2004043958A1 (en) 2002-11-06 2004-05-27 Amgen Inc. Fused heterocyclic compounds
CA2515717A1 (en) 2003-02-10 2004-08-19 Banyu Pharmaceutical Co., Ltd. Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient
DE102010025663A1 (de) * 2010-06-30 2012-01-05 Karl-Heinz Glüsenkamp Neue beta-Aminoaldehyd-Derivate, Verfahren zu ihrer Herstellung und ihre chemische Verwendung als reaktive Intermediate
WO2012019315A1 (en) 2010-08-10 2012-02-16 Abbott Laboratories Novel trpv3 modulators
US9012651B2 (en) 2011-03-24 2015-04-21 Abbvie Inc. TRPV3 modulators
CA2853097A1 (en) 2011-10-24 2013-05-02 Abbvie Inc. Novel trpv3 modulators
CN106588812B (zh) * 2016-12-07 2019-02-22 烟台大学 一种酰氯制备2，4-二取代噻唑啉类化合物的方法
FI3911631T3 (fi) * 2019-01-14 2025-02-03 Zydus Lifesciences Ltd Uusia substituoituja sulfonyyliureajohdannaisia
HUP2200222A1 (hu) 2022-06-17 2023-12-28 Richter Gedeon Nyrt MCHR1 antagonisták a Prader-Willi szindróma kezelésére

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US23085A (en) * 1859-03-01 chandler
US199549A (en) * 1878-01-22 Improvement in screw-propellers
US176694A (en) * 1876-04-25 Improvement in screw-cutting die-stocks
JPS5825980B2 (ja) 1976-02-12 1983-05-31 ヤマサ醤油株式会社 サイクリックヌクレオチドの定量法
EP0257701A1 (en) 1986-08-15 1988-03-02 Cedona Pharmaceuticals B.V. A process for preparing hydroxyl derivatives of compounds containing a carbazole, dibenzofurane or dibenzothiophene group
US5049655A (en) 1989-03-22 1991-09-17 The Salk Institute For Biological Studies Melanin-concentrating hormones
JP2906654B2 (ja) 1989-11-28 1999-06-21 東レ株式会社 免疫抑制剤及びその製造方法
US5401629A (en) 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
JP3160941B2 (ja) 1991-06-17 2001-04-25 東レ株式会社 カルバゾール誘導体および免疫抑制剤
ES2173866T3 (es) 1991-07-05 2002-11-01 Glaxosmithkline Spa Derivados de hidroisoquinolina.
JP3605825B2 (ja) 1992-09-29 2004-12-22 東レ株式会社 インドール誘導体，その製造方法およびその医薬用途
US5272146A (en) 1992-10-02 1993-12-21 The United States Of America As Represented By The United States Department Of Health And Human Services 1,2-dihydroellipticines with activity against CNS specific cancer cell lines
US5457208A (en) 1993-06-21 1995-10-10 Regents Of The University Of Minnesota Kappa opioid receptor antagonists
US5464841A (en) 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
US5578725A (en) 1995-01-30 1996-11-26 Regents Of The University Of Minnesota Delta opioid receptor antagonists
US5849708A (en) 1995-06-06 1998-12-15 Joslin Diabetes Center, Inc. Promotion of eating behavior
EP0848060A3 (en) 1996-12-11 2000-02-02 Smithkline Beecham Corporation Novel human 11CB splice variant
EP0894799B1 (en) 1997-01-16 2004-04-07 Toray Industries, Inc. Indolomorphinane derivatives and remedies/preventives for cerebral disorders
US6555339B1 (en) 1997-04-14 2003-04-29 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human protein-coupled receptors
WO1999028492A1 (en) 1997-12-03 1999-06-10 Smithkline Beecham Corporation A method of finding agonist and antagonist to human 11cb splice variant
WO1999064002A1 (en) 1998-06-11 1999-12-16 Merck & Co., Inc. Spiropiperidine derivatives as melanocortin receptor agonists
CA2342833A1 (en) 1998-09-17 2000-03-23 Incyte Pharmaceuticals, Inc. Human gpcr proteins
GB9822158D0 (en) 1998-10-09 1998-12-02 Nycomed Imaging As Compositions
CN1344321A (zh) 1998-12-28 2002-04-10 武田药品工业株式会社 筛选方法
US6221613B1 (en) 1998-12-31 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof
WO2000049170A1 (en) 1999-02-18 2000-08-24 Smithkline Beecham Corporation MURINE 11cby RECEPTOR
EP1153932A1 (en) 1999-02-19 2001-11-14 Takeda Chemical Industries, Ltd. Novel g protein-coupled receptor protein and dna thereof
WO2000070347A1 (en) 1999-05-19 2000-11-23 Astrazeneca Ab Assays for agonists, agonists and inverse agonists of melanin concentrating hormone (mch) binding to the somatostatin-like receptor (slc-1)
WO2000075166A1 (en) 1999-06-08 2000-12-14 The Regents Of The University Of California Melanin concentrating hormone receptor
EP1200560A4 (en) 1999-07-14 2003-06-11 Merck & Co Inc MELANINE-CONCENTRATING HORMONE RECEPTOR
AU6117000A (en) 1999-07-26 2001-02-13 Genentech Inc. Novel polynucleotides and method of use thereof
WO2001007606A1 (en) 1999-07-27 2001-02-01 Smithkline Beecham Plc Axor21, a g-protein coupled receptor
WO2001021169A1 (en) 1999-09-20 2001-03-29 Takeda Chemical Industries, Ltd. Mch antagonists
US7115750B1 (en) 1999-09-20 2006-10-03 Takeda Pharmaceutical Company Limited Melanin concentrating hormone antagonist
JP2003514549A (ja) 1999-11-16 2003-04-22 メルク エンド カムパニー インコーポレーテッド Ｇタンパク質共役受容体
JP2001226269A (ja) 2000-02-18 2001-08-21 Takeda Chem Ind Ltd メラニン凝集ホルモン拮抗剤
WO2001068706A1 (en) 2000-03-15 2001-09-20 Merck & Co., Inc. Melanin concentrating hormone receptor chimeric and fusion proteins
JP2005229804A (ja) 2000-03-24 2005-09-02 Astellas Pharma Inc 新規なメラニンコンセントレーティングホルモン受容体
CA2408913A1 (en) 2000-05-16 2001-11-22 Takeda Chemical Industries, Ltd. Melanin-concentrating hormone antagonist
CA2384041A1 (en) 2000-07-05 2002-01-24 Synaptic Pharmaceuticals Corporation Selective melanin concentrating hormone-1 (mch1) receptor antagonists and uses thereof
ATE489626T1 (de) 2000-07-05 2010-12-15 Takeda Pharmaceutical Verfahren zum screenen von mhc- rezeptorantagonisten oder -agonisten
WO2002002744A2 (en) 2000-07-05 2002-01-10 Synaptic Pharmaceutical Corporation Dna encoding a human melanin concentrating hormone receptor (mch1) and uses thereof
US6569861B2 (en) * 2000-07-06 2003-05-27 Neurogen Corporation Melanin concentrating hormone receptor ligands
CA2423792A1 (en) 2000-10-20 2002-04-25 Pfizer Products Inc. Alpha-aryl ethanolamines and their use as beta-3 adrenergic receptor agonists
US20030022891A1 (en) 2000-12-01 2003-01-30 Anandan Palani MCH antagonists and their use in the treatment of obesity
NZ525723A (en) 2000-12-22 2004-11-26 Schering Corp 1,4-di-substituted piperidine antagonists for melanin-concentrating hormone (MCH) and their use in the treatment of obesity or diabetes
US6900329B2 (en) 2001-03-21 2005-05-31 Schering Corporation MCH antagonists and their use in the treatment of obesity
KR20030093257A (ko) 2001-03-21 2003-12-06 파마코페이아, 인크. Ｍｃｈ 조정 활성을 지닌 아릴 및 바이아릴 화합물
ATE460163T1 (de) * 2001-04-12 2010-03-15 Pharmacopeia Llc Arly und diaryl piperidinderivate verwendbar als mch-hemmer
US6809104B2 (en) 2001-05-04 2004-10-26 Tularik Inc. Fused heterocyclic compounds
WO2002089729A2 (en) * 2001-05-04 2002-11-14 Tularik Inc. Fused heterocyclic compounds
IL158941A0 (en) 2001-05-22 2004-05-12 Neurogen Corp Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues
AR037429A1 (es) * 2001-11-26 2004-11-10 Schering Corp Derivados de piperidina antagonistas de la mch, composiciones farmaceuticas, un proceso para su elaboracion y el uso de dichos derivados, solos o en combinacion, para la fabricacion de un medicamento para tratamiento de la obesidad y de trastornos del snc
EP1465635A4 (en) 2002-01-10 2005-04-13 Neurogen Corp MELANIN-CONCENTRATING HORMONIC RECEPTOR LIGANDS: SUBSTITUTED 2- (4-BENZYL-PIPERAZIN-1-YLMETHYL) AND 2- (4-BENZYL-DIAZEPAN-1-YLMETHYL) -1H-BENZOIMIDAZOLE ANALOGUES
WO2004043958A1 (en) * 2002-11-06 2004-05-27 Amgen Inc. Fused heterocyclic compounds

Also Published As

Publication number Publication date
US7253179B2 (en) 2007-08-07
MXPA05004739A (es) 2005-08-02
CN101134757A (zh) 2008-03-05
ZA200503654B (en) 2006-09-27
KR20050103184A (ko) 2005-10-27
CA2505372A1 (en) 2004-05-27
NO20052655L (no) 2005-07-26
AU2003285160A1 (en) 2004-06-03
BR0316070A (pt) 2005-09-27
US20080058365A1 (en) 2008-03-06
EA009421B1 (ru) 2007-12-28
CN1735613A (zh) 2006-02-15
JP2006508130A (ja) 2006-03-09
CN1330651C (zh) 2007-08-08
US20040147538A1 (en) 2004-07-29
AU2003285160B2 (en) 2009-06-04
WO2004043958A1 (en) 2004-05-27
EA200500770A1 (ru) 2005-12-29
NO20052655D0 (no) 2005-06-02
PL376659A1 (pl) 2006-01-09
NZ540328A (en) 2008-02-29
JP4547266B2 (ja) 2010-09-22
EP1562943A1 (en) 2005-08-17

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