IS7926A - 4-útskipt bensímídasól og notkun þeirra sem magasýruseytishemla - Google Patents

4-útskipt bensímídasól og notkun þeirra sem magasýruseytishemla

Info

Publication number
IS7926A
IS7926A IS7926A IS7926A IS7926A IS 7926 A IS7926 A IS 7926A IS 7926 A IS7926 A IS 7926A IS 7926 A IS7926 A IS 7926A IS 7926 A IS7926 A IS 7926A
Authority
IS
Iceland
Prior art keywords
antacids
substituted benzimidazole
benzimidazole
substituted
Prior art date
Application number
IS7926A
Other languages
English (en)
Inventor
Buhr Wilm
Jan Zimmermann Peter
Vittoria Chiesa M.
Palmer Andreas
Brehm Christof
Grundler Gerhard
Senn-Bilfinger Jörg
Simon Wolfgang-Alexander
Postius Stefan
Kromer Wolfgang
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of IS7926A publication Critical patent/IS7926A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS7926A 2002-12-13 2005-07-01 4-útskipt bensímídasól og notkun þeirra sem magasýruseytishemla IS7926A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02027874 2002-12-13
EP03021348 2003-09-20
PCT/EP2003/014069 WO2004054984A1 (en) 2002-12-13 2003-12-11 4-substituted benzimidazoles and their use as inhibitors of gastric secretion

Publications (1)

Publication Number Publication Date
IS7926A true IS7926A (is) 2005-07-01

Family

ID=32598782

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7926A IS7926A (is) 2002-12-13 2005-07-01 4-útskipt bensímídasól og notkun þeirra sem magasýruseytishemla

Country Status (19)

Country Link
US (1) US20060194969A1 (is)
EP (1) EP1575924A1 (is)
JP (1) JP2006511600A (is)
KR (1) KR20050084170A (is)
AR (1) AR043063A1 (is)
AU (1) AU2003294831A1 (is)
BR (1) BR0317041A (is)
CA (1) CA2508838A1 (is)
CO (1) CO5580786A2 (is)
EA (1) EA008779B1 (is)
HR (1) HRP20050612A2 (is)
IS (1) IS7926A (is)
MX (1) MXPA05006052A (is)
NO (1) NO20053242L (is)
NZ (1) NZ540862A (is)
PL (1) PL375820A1 (is)
RS (1) RS20050435A (is)
TW (1) TW200504031A (is)
WO (1) WO2004054984A1 (is)

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* Cited by examiner, † Cited by third party
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WO2004087701A1 (en) 2003-04-04 2004-10-14 Altana Pharma Ag Cyclic benzimidazoles
AR049168A1 (es) * 2004-05-18 2006-07-05 Altana Pharma Ag Derivados de benzimidazol
US20080119510A1 (en) * 2004-12-09 2008-05-22 Altana Pharma Ag Substituted Imidazo [4,5-B] Pyridines As Inhibitors Of Gastric Acid Secretion
JP2008534475A (ja) * 2005-03-24 2008-08-28 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 6−チアミド置換されたベンゾイミダゾール
DE602006009105D1 (de) * 2005-06-14 2009-10-22 Raqualia Pharma Inc Chroman-substituierte benzimidazolderivate als säurepumpenantagonisten
AR057061A1 (es) * 2005-06-16 2007-11-14 Altana Pharma Ag Espiro-bencimidazoles farmaceuticamente activos y su uso en la fabricacion de medicamentos
JP2009504798A (ja) * 2005-08-22 2009-02-05 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 同位体置換されたベンゾイミダゾール誘導体
WO2007031860A1 (en) * 2005-09-15 2007-03-22 Pfizer Japan Inc. Indane substituted benzimidazoles and their use as acid pump inhibitors
KR101088247B1 (ko) 2005-12-19 2011-11-30 라퀄리아 파마 인코포레이티드 크로메인 치환된 벤즈이미다졸 및 이들의 산 펌프억제제로서의 용도
WO2007072142A2 (en) * 2005-12-19 2007-06-28 Pfizer Japan Inc. Benzimidazole-5-carboxamide derivatives
WO2008017466A1 (en) * 2006-08-08 2008-02-14 Nycomed Gmbh Pharmaceutically active tetrahydroisoquinoline-substituted benzimidazole derivatives
JP5140080B2 (ja) 2006-09-21 2013-02-06 ラクオリア創薬株式会社 選択的アシッドポンプ阻害剤としてのベンゾイミダゾール誘導体
WO2008071765A1 (en) * 2006-12-14 2008-06-19 Nycomed Gmbh Pharmaceutically active spiro-substituted benzimidazole derivatives
WO2008084067A2 (en) * 2007-01-12 2008-07-17 Nycomed Gmbh Pharmaceutically active dihydrobenzofurane-substituted benzimidazole derivatives
WO2008151927A2 (en) * 2007-06-15 2008-12-18 Nycomed Gmbh 6-n-substituted benz imidazole derivatives as acid pump antagonists
ES2424214T3 (es) 2007-08-27 2013-09-30 Siga Technologies, Inc. Medicamentos antivirales para el tratamiento de una infección por Arenavirus
WO2010081670A2 (en) * 2009-01-14 2010-07-22 Lonza Ltd Process for the preparation of benzimidazoles
KR101605063B1 (ko) 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제
WO2012081036A2 (en) * 2010-12-13 2012-06-21 Sequent Scientific Limited A process for preparation of 4,4'-(1-methyl-1,2-ethandiyl)-bis-(2,6-piperazinedione)
RU2506259C1 (ru) * 2012-12-04 2014-02-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный университет им. П.Г. Демидова" Способ получения 4-{4-амино-2-хлоро-5-[(5-хлоро-2-метил-1н-бензимидазол-6-ил)амино]фенокси}бензойной кислоты
WO2014124458A1 (en) 2013-02-11 2014-08-14 The Regents Of The University Of California Compositions and methods for treating neurodegenerative diseases
SI3010503T1 (sl) 2013-06-21 2020-07-31 Zenith Epigenetics Ltd. Novi biciklični inhibitorji bromodomene
JP6461118B2 (ja) 2013-06-21 2019-01-30 ゼニス・エピジェネティクス・リミテッドZenith Epigenetics Ltd. ブロモドメイン阻害剤としての新規の置換された二環式化合物
KR101472686B1 (ko) 2013-07-09 2014-12-16 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 제조방법
JP6542212B2 (ja) 2013-07-31 2019-07-10 ゼニス・エピジェネティクス・リミテッドZenith Epigenetics Ltd. ブロモドメイン阻害剤としての新規キナゾリノン
US10710992B2 (en) 2014-12-01 2020-07-14 Zenith Epigenetics Ltd. Substituted pyridinones as bromodomain inhibitors
WO2016092375A1 (en) 2014-12-11 2016-06-16 Zenith Epigenetics Corp. Substituted heterocycles as bromodomain inhibitors
CA2966450A1 (en) 2014-12-17 2016-06-23 Olesya KHARENKO Inhibitors of bromodomains
KR101684053B1 (ko) 2015-01-20 2016-12-08 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 신규 결정형 및 이의 제조방법
HUE056322T2 (hu) * 2015-06-08 2022-02-28 Hk Inno N Corp Benzimidazol-származék alkalmazásai éjszakai savvisszaáramláshoz
AU2018290225A1 (en) 2017-06-21 2020-01-23 Mitokinin, Inc. Compositions and methods using the same for treatment of neurodegenerative and mitochondrial disease
EP3920930A4 (en) * 2019-02-04 2023-03-08 Simon Fraser University METHODS AND COMPOUNDS FOR INHIBITING THE INACTIVATION OF VOLTAGE CONTROLLED SODIUM CHANNELS
CN113527272B (zh) * 2021-08-06 2023-07-21 西安淳甄新材料有限公司 一种特戈拉赞的合成方法
KR102708701B1 (ko) 2021-12-27 2024-09-24 에이치케이이노엔 주식회사 벤즈이미다졸 유도체의 제조방법
WO2024210689A1 (ko) * 2023-04-07 2024-10-10 제이더블유중외제약 주식회사 벤즈이미다졸 유도체의 염
WO2025111224A1 (en) * 2023-11-21 2025-05-30 Fmc Corporation Linked bicyclic compounds for controlling and combating invertebrate pests

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SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
SE9602286D0 (sv) * 1996-06-10 1996-06-10 Astra Ab New compounds

Also Published As

Publication number Publication date
NO20053242D0 (no) 2005-07-01
HRP20050612A2 (en) 2006-08-31
JP2006511600A (ja) 2006-04-06
EP1575924A1 (en) 2005-09-21
AU2003294831A1 (en) 2004-07-09
CO5580786A2 (es) 2005-11-30
BR0317041A (pt) 2005-10-25
PL375820A1 (en) 2005-12-12
TW200504031A (en) 2005-02-01
WO2004054984A1 (en) 2004-07-01
CA2508838A1 (en) 2004-07-01
RS20050435A (sr) 2007-08-03
NO20053242L (no) 2005-07-01
EA200500895A1 (ru) 2005-12-29
MXPA05006052A (es) 2005-08-18
KR20050084170A (ko) 2005-08-26
EA008779B1 (ru) 2007-08-31
AR043063A1 (es) 2005-07-13
US20060194969A1 (en) 2006-08-31
NZ540862A (en) 2008-07-31

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