IS7926A - 4-útskipt bensímídasól og notkun þeirra sem magasýruseytishemla - Google Patents

4-útskipt bensímídasól og notkun þeirra sem magasýruseytishemla

Info

Publication number
IS7926A
IS7926A IS7926A IS7926A IS7926A IS 7926 A IS7926 A IS 7926A IS 7926 A IS7926 A IS 7926A IS 7926 A IS7926 A IS 7926A IS 7926 A IS7926 A IS 7926A
Authority
IS
Iceland
Prior art keywords
antacids
substituted benzimidazole
benzimidazole
substituted
Prior art date
Application number
IS7926A
Other languages
English (en)
Inventor
Buhr Wilm
Jan Zimmermann Peter
Vittoria Chiesa M.
Palmer Andreas
Brehm Christof
Grundler Gerhard
Senn-Bilfinger Jörg
Simon Wolfgang-Alexander
Postius Stefan
Kromer Wolfgang
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of IS7926A publication Critical patent/IS7926A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS7926A 2002-12-13 2005-07-01 4-útskipt bensímídasól og notkun þeirra sem magasýruseytishemla IS7926A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02027874 2002-12-13
EP03021348 2003-09-20
PCT/EP2003/014069 WO2004054984A1 (en) 2002-12-13 2003-12-11 4-substituted benzimidazoles and their use as inhibitors of gastric secretion

Publications (1)

Publication Number Publication Date
IS7926A true IS7926A (is) 2005-07-01

Family

ID=32598782

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7926A IS7926A (is) 2002-12-13 2005-07-01 4-útskipt bensímídasól og notkun þeirra sem magasýruseytishemla

Country Status (19)

Country Link
US (1) US20060194969A1 (is)
EP (1) EP1575924A1 (is)
JP (1) JP2006511600A (is)
KR (1) KR20050084170A (is)
AR (1) AR043063A1 (is)
AU (1) AU2003294831A1 (is)
BR (1) BR0317041A (is)
CA (1) CA2508838A1 (is)
CO (1) CO5580786A2 (is)
EA (1) EA008779B1 (is)
HR (1) HRP20050612A2 (is)
IS (1) IS7926A (is)
MX (1) MXPA05006052A (is)
NO (1) NO20053242L (is)
NZ (1) NZ540862A (is)
PL (1) PL375820A1 (is)
RS (1) RS20050435A (is)
TW (1) TW200504031A (is)
WO (1) WO2004054984A1 (is)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004087701A1 (en) 2003-04-04 2004-10-14 Altana Pharma Ag Cyclic benzimidazoles
AR049168A1 (es) * 2004-05-18 2006-07-05 Altana Pharma Ag Derivados de benzimidazol
EP1824850A2 (en) * 2004-12-09 2007-08-29 Nycomed GmbH SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS INHIBITORS OF GASTRIC ACID SECRETION
WO2006100254A1 (en) * 2005-03-24 2006-09-28 Nycomed Gmbh 6-thioamide substituted benzimidazoles
JP2008543824A (ja) * 2005-06-14 2008-12-04 ファイザー株式会社 アシッドポンプアンタゴニストとしてのクロマン置換ベンゾイミダゾール誘導体
AR057061A1 (es) * 2005-06-16 2007-11-14 Altana Pharma Ag Espiro-bencimidazoles farmaceuticamente activos y su uso en la fabricacion de medicamentos
AU2006283876A1 (en) * 2005-08-22 2007-03-01 Nycomed Gmbh Isotopically substituted benzimidazole derivatives
WO2007031860A1 (en) * 2005-09-15 2007-03-22 Pfizer Japan Inc. Indane substituted benzimidazoles and their use as acid pump inhibitors
WO2007072142A2 (en) * 2005-12-19 2007-06-28 Pfizer Japan Inc. Benzimidazole-5-carboxamide derivatives
WO2007072146A1 (en) * 2005-12-19 2007-06-28 Pfizer Japan Inc. Chromane substituted benzimidazoles and their use as acid pump inhibitors
WO2008017466A1 (en) * 2006-08-08 2008-02-14 Nycomed Gmbh Pharmaceutically active tetrahydroisoquinoline-substituted benzimidazole derivatives
JP5140080B2 (ja) 2006-09-21 2013-02-06 ラクオリア創薬株式会社 選択的アシッドポンプ阻害剤としてのベンゾイミダゾール誘導体
WO2008071765A1 (en) * 2006-12-14 2008-06-19 Nycomed Gmbh Pharmaceutically active spiro-substituted benzimidazole derivatives
WO2008084067A2 (en) * 2007-01-12 2008-07-17 Nycomed Gmbh Pharmaceutically active dihydrobenzofurane-substituted benzimidazole derivatives
WO2008151927A2 (en) * 2007-06-15 2008-12-18 Nycomed Gmbh 6-n-substituted benz imidazole derivatives as acid pump antagonists
CA2698075C (en) * 2007-08-27 2016-04-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
WO2010081670A2 (en) * 2009-01-14 2010-07-22 Lonza Ltd Process for the preparation of benzimidazoles
EP2452680B1 (en) 2009-07-09 2019-12-18 RaQualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
WO2012081036A2 (en) * 2010-12-13 2012-06-21 Sequent Scientific Limited A process for preparation of 4,4'-(1-methyl-1,2-ethandiyl)-bis-(2,6-piperazinedione)
RU2506259C1 (ru) * 2012-12-04 2014-02-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный университет им. П.Г. Демидова" Способ получения 4-{4-амино-2-хлоро-5-[(5-хлоро-2-метил-1н-бензимидазол-6-ил)амино]фенокси}бензойной кислоты
AU2014214561C1 (en) 2013-02-11 2019-01-17 Mitokinin, Inc. Compositions and methods for treating neurodegenerative diseases
CN105473581B (zh) * 2013-06-21 2019-04-23 齐尼思表观遗传学有限公司 作为溴结构域抑制剂的新取代的双环化合物
KR102307566B1 (ko) 2013-06-21 2021-10-05 제니쓰 에피제네틱스 리미티드 신규한 바이사이클릭 브로모도메인 억제제
KR101472686B1 (ko) 2013-07-09 2014-12-16 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 제조방법
CA2919948C (en) 2013-07-31 2020-07-21 Zenith Epigenetics Corp. Novel quinazolinones as bromodomain inhibitors
HK1245246A1 (zh) 2014-12-01 2018-08-24 恒翼生物医药科技(上海)有限公司 作为溴域抑制剂的取代吡啶酮
WO2016092375A1 (en) 2014-12-11 2016-06-16 Zenith Epigenetics Corp. Substituted heterocycles as bromodomain inhibitors
CN107406438B (zh) 2014-12-17 2021-05-14 恒翼生物医药科技(上海)有限公司 溴结构域的抑制剂
KR101684053B1 (ko) 2015-01-20 2016-12-08 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 신규 결정형 및 이의 제조방법
MA41730B1 (fr) * 2015-06-08 2019-03-29 Cj Healthcare Corp Utilisation de dérivé de benzimidazole pour l'acidité nocturne
WO2018237145A1 (en) 2017-06-21 2018-12-27 Mitokinin, Inc. Compositions and methods using the same for treatment of neurodegenerative and mitochondrial disease
US20220125784A1 (en) * 2019-02-04 2022-04-28 Simon Fraser University Methods and compounds for inhibition of inactivation of voltage-gated sodium channels
CN113527272B (zh) * 2021-08-06 2023-07-21 西安淳甄新材料有限公司 一种特戈拉赞的合成方法
KR102708701B1 (ko) 2021-12-27 2024-09-24 에이치케이이노엔 주식회사 벤즈이미다졸 유도체의 제조방법
WO2024210689A1 (ko) * 2023-04-07 2024-10-10 제이더블유중외제약 주식회사 벤즈이미다졸 유도체의 염
WO2025111224A1 (en) * 2023-11-21 2025-05-30 Fmc Corporation Linked bicyclic compounds for controlling and combating invertebrate pests

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
SE9602286D0 (sv) * 1996-06-10 1996-06-10 Astra Ab New compounds

Also Published As

Publication number Publication date
WO2004054984A1 (en) 2004-07-01
PL375820A1 (en) 2005-12-12
KR20050084170A (ko) 2005-08-26
EA008779B1 (ru) 2007-08-31
HRP20050612A2 (en) 2006-08-31
MXPA05006052A (es) 2005-08-18
NO20053242D0 (no) 2005-07-01
NZ540862A (en) 2008-07-31
EP1575924A1 (en) 2005-09-21
JP2006511600A (ja) 2006-04-06
NO20053242L (no) 2005-07-01
TW200504031A (en) 2005-02-01
EA200500895A1 (ru) 2005-12-29
AU2003294831A1 (en) 2004-07-09
US20060194969A1 (en) 2006-08-31
RS20050435A (sr) 2007-08-03
CO5580786A2 (es) 2005-11-30
CA2508838A1 (en) 2004-07-01
BR0317041A (pt) 2005-10-25
AR043063A1 (es) 2005-07-13

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