IS8071A - Aðferð við meðhöndlun á hnútahersli, fitudreyra og tengdum ástands tegundum og lyfjafræðilegum samsetningum - Google Patents

Aðferð við meðhöndlun á hnútahersli, fitudreyra og tengdum ástands tegundum og lyfjafræðilegum samsetningum

Info

Publication number: IS8071A
Authority: IS; Iceland
Prior art keywords: liposuction; scoliosis; nodular; treatment; pharmaceutical compositions
Prior art date: 2003-05-15

Application number

IS8071A

Other languages

English (en)

Other versions

IS2708B (is

Inventor

Cheng Kang

M. Waters Gerard

M. Metters Kathleen

O'neill Gary

Original Assignee

Merck & Co., Inc.

Merck Frosst Canada Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-15

Filing date

2005-10-13

Publication date

2005-10-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33476734&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS8071(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-10-13 Application filed by Merck & Co., Inc., Merck Frosst Canada Ltd. filed Critical Merck & Co., Inc.

2005-10-13 Publication of IS8071A publication Critical patent/IS8071A/is

2011-01-15 Publication of IS2708B publication Critical patent/IS2708B/is

Links

238000007443 liposuction Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
206010039722 scoliosis Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IS8071A 2003-05-15 2005-10-13 Aðferð til að meðhöndla hnútahersli, blóðfituröskun og tengdar ástandstegundir og lyfjasamsetningar IS2708B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US47066503P	2003-05-15	2003-05-15
PCT/US2004/014980 WO2004103370A1 (en)	2003-05-15	2004-05-13	Method of treating atherosclerosis, dyslipidemias and related conditions and pharmaceutical compositions

Publications (2)

Publication Number	Publication Date
IS8071A true IS8071A (is)	2005-10-13
IS2708B IS2708B (is)	2011-01-15

Family

ID=33476734

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS8071A IS2708B (is)	2003-05-15	2005-10-13	Aðferð til að meðhöndla hnútahersli, blóðfituröskun og tengdar ástandstegundir og lyfjasamsetningar

Country Status (44)

Country	Link
US (4)	US20040229844A1 (is)
EP (3)	EP2286816A1 (is)
JP (2)	JP4637833B2 (is)
KR (2)	KR100960749B1 (is)
CN (3)	CN101559227B (is)
AR (1)	AR041089A1 (is)
AU (2)	AU2004240597B2 (is)
BR (1)	BRPI0410273A (is)
CA (1)	CA2525772C (is)
CL (1)	CL2004001056A1 (is)
CO (1)	CO5630034A2 (is)
CR (2)	CR8047A (is)
CY (2)	CY1109476T1 (is)
DE (1)	DE602004022036D1 (is)
DK (2)	DK2116244T3 (is)
DO (1)	DOP2004000907A (is)
EA (2)	EA009744B1 (is)
EC (1)	ECSP056156A (is)
ES (2)	ES2328148T3 (is)
GE (2)	GEP20105025B (is)
GT (1)	GT200400098A (is)
HN (1)	HN2004000171A (is)
HR (2)	HRP20090424T1 (is)
IL (1)	IL171962A (is)
IS (1)	IS2708B (is)
JO (1)	JO2564B1 (is)
MA (1)	MA27835A1 (is)
ME (1)	MEP60108A (is)
MX (1)	MXPA05012272A (is)
MY (1)	MY140639A (is)
NO (1)	NO20055957L (is)
NZ (2)	NZ572515A (is)
PA (1)	PA8603201A1 (is)
PE (1)	PE20050552A1 (is)
PL (2)	PL1624871T3 (is)
PT (2)	PT1624871E (is)
RS (3)	RS20120499A1 (is)
SG (1)	SG153667A1 (is)
SI (2)	SI2116244T1 (is)
TN (1)	TNSN05290A1 (is)
TW (2)	TWI341199B (is)
UA (1)	UA89615C2 (is)
WO (1)	WO2004103370A1 (is)
ZA (1)	ZA200508288B (is)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60215000T2 (de) *	2001-05-23	2007-08-09	Merck Frosst Canada & Co, Kirkland	Dihydropyrroloil[1,2-a]indol- und Tetrahydropyridol[1,2-a]indol-Derivate als Prostaglandin-D2-Rezeptor-Antagonisten
US7094572B2 (en) *	2003-03-14	2006-08-22	Bristol-Myers Squibb	Polynucleotide encoding a novel human G-protein coupled receptor variant of HM74, HGPRBMY74
TWI258478B (en)	2003-10-31	2006-07-21	Arena Pharm Inc	Tetrazole derivatives and methods of treatment of metabolic-related disorders thereof
US7019022B2 (en) *	2003-12-15	2006-03-28	Merck Frosst Canada & Co.	Substituted tetrahydrocarbazole and cyclopentanoindole derivatives
SI1799196T1 (sl)	2004-10-08	2016-10-28	Forward Pharma A/S	Farmacevtski sestavki z nadzorovanim sproščanjem, obsegajoči ester fumarne kisline
PE20060949A1 (es)	2004-12-23	2006-10-11	Arena Pharm Inc	Derivados fusionados de pirazol como agonistas del receptor de niacina
WO2006078776A2 (en) *	2005-01-19	2006-07-27	The Trustees Of The University Of Pennsylvania	Inhibitors and methods of treatment of cardiovascular diseases, and methods for identifying inhibitors
CA2598273A1 (en) *	2005-02-17	2006-08-24	Merck & Co., Inc.	Method of treating atherosclerosis, dyslipidemias and related conditions
AU2006214286A1 (en) *	2005-02-18	2006-08-24	Arena Pharmaceuticals, Inc.	Methods and compositions for the treatment of lipid-associated disorders
US7750015B2 (en) *	2005-05-17	2010-07-06	Schering Corporation	Nitrogen-containing heterocyclic compounds and methods of use thereof
BRPI0610133A2 (pt) *	2005-05-17	2010-06-01	Schering Corp	heterociclos como agonistas de receptor de ácido nicotìnico para o tratamento de dislipidemia
US7737155B2 (en) *	2005-05-17	2010-06-15	Schering Corporation	Nitrogen-containing heterocyclic compounds and methods of use thereof
JP2009507791A (ja) *	2005-08-29	2009-02-26	メルクエンドカムパニーインコーポレーテッド	ナイアシン受容体アゴニスト、このような化合物を含有する組成物、および治療方法
AU2006284751A1 (en) *	2005-09-01	2007-03-08	Array Biopharma Inc.	Raf inhibitor compounds and methods of use thereof
EP1940382A2 (en) *	2005-10-07	2008-07-09	Aditech Pharma AB	Combination therapy with fumaric acid esters for the treatment of autoimmune and/or inflammatory disorders
CA2634235A1 (en) *	2005-12-21	2007-07-05	Schering Corporation	Combination of an h3 antagonist/inverse agonist and an appetite suppressant
CA2634940A1 (en) *	2005-12-21	2007-07-05	Schering Corporation	Treatment of nonalcoholic fatty liver disease using cholesterol lowering agents and h3 receptor antagonist/inverse agonist
AU2007208478A1 (en) *	2006-01-20	2007-08-02	Schering Corpooration	Heterocycles as nicotinic acid receptor agonists for the treatment of dyyslipidemia
US20090069275A1 (en) *	2006-02-17	2009-03-12	Rocca Jose G	Low flush niacin formulation
MX2009002918A (es) *	2006-09-15	2009-03-31	Schering Corp	Derivados azetidinona y sus metodos de uso.
MX2009002921A (es) *	2006-09-15	2009-04-01	Schering Corp	Derivados de azetidinona para el tratamiento de trastornos del metabolismo lipidico.
WO2008033431A1 (en)	2006-09-15	2008-03-20	Schering Corporation	Spirocyclic azetidinone derivatives for the treatment of disorders of lipid metabolism, pain, diabetes and other disorders
WO2008039882A1 (en) *	2006-09-30	2008-04-03	Sanofi-Aventis U.S. Llc	A combination of niacin and a prostaglandin d2 receptor antagonist
WO2008097535A2 (en) *	2007-02-08	2008-08-14	Merck & Co., Inc.	Method of treating atherosclerosis, dyslipidemias and related conditions
US20090076117A1 (en) *	2007-09-17	2009-03-19	Protia, Llc	Deuterium-enriched laropiprant
CN101559058B (zh) *	2008-04-16	2011-07-20	北京本草天源药物研究院	一种治疗血脂异常的药物组合物
RU2010151944A (ru) *	2008-05-20	2012-06-27	Серенис Терапьютикс С.А. (Fr)	Ниацин и нспвс для комбинированной терапии
WO2010030360A1 (en)	2008-09-11	2010-03-18	Arena Pharmaceuticals, Inc.	3H-IMIDAZO[4,5-b]PYRIDIN-5-OL DERIVATIVES USEFUL IN THE TREATMENT OF GPR81 RECEPTOR DISORDERS
WO2010036600A1 (en) *	2008-09-24	2010-04-01	Merck Sharp & Dohme Corp.	Pharmaceutical compositions of atorvastatin
US20110245209A1 (en)	2008-12-16	2011-10-06	Schering Corporation	Pyridopyrimidine derivatives and methods of use thereof
US20110243940A1 (en)	2008-12-16	2011-10-06	Schering Corporation	Bicyclic pyranone derivatives and methods of use thereof
EP2564839B1 (en)	2009-01-09	2016-05-11	Forward Pharma A/S	Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix
MX2012010038A (es)	2010-03-16	2012-10-01	Aventis Pharma Inc	Una pirimidina sustituida como un antagonista del receptor de la prostaglandina d2.
CA2793223A1 (en)	2010-03-16	2011-09-22	Aventis Pharmaceuticals Inc.	Substituted pyrimidines as prostaglandin d2 receptor antagonists
JP6770522B2 (ja)	2015-02-13	2020-10-14	アンスティチュナショナルドゥラサンテエドゥラルシェルシュメディカル	全身性エリテマトーデスを予防し、及び／又は、治療するためのｐｔｇｄｒ−１及び／又はｐｔｇｄｒ−２アンタゴニスト

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3535326A (en) *	1967-03-06	1970-10-20	Sumitomo Chemical Co	Certain tetrahydro carboline derivatives
BE787444A (fr) *	1971-08-13	1973-02-12	Hoffmann La Roche	Composes polycycliques
US4009181A (en) *	1973-01-22	1977-02-22	Hoffmann-La Roche Inc.	Cyclopenta[b]indole-2-carboxylic acids and derivatives thereof
US4057559A (en) *	1973-10-01	1977-11-08	American Home Products Corporation	Carbazole acetic acid derivatives
US4166452A (en)	1976-05-03	1979-09-04	Generales Constantine D J Jr	Apparatus for testing human responses to stimuli
US4256108A (en)	1977-04-07	1981-03-17	Alza Corporation	Microporous-semipermeable laminated osmotic system
WO1979000169A1 (en)	1977-09-30	1979-04-05	Rca Corp	Television system scheduler
US4342767A (en)	1980-01-23	1982-08-03	Merck & Co., Inc.	Hypocholesteremic fermentation products
US4444784A (en)	1980-08-05	1984-04-24	Merck & Co., Inc.	Antihypercholesterolemic compounds
US4265874A (en)	1980-04-25	1981-05-05	Alza Corporation	Method of delivering drug with aid of effervescent activity generated in environment of use
MX7065E (es)	1980-06-06	1987-04-10	Sankyo Co	Un procedimiento microbiologico para preparar derivados de ml-236b
US5354772A (en)	1982-11-22	1994-10-11	Sandoz Pharm. Corp.	Indole analogs of mevalonolactone and derivatives thereof
US5021447A (en) *	1986-01-23	1991-06-04	Merck Frosst Canada, Inc.	Tetrahydrocarbazole 1-alkanoic acids and pharmaecutical compositions
US4808608A (en) *	1986-01-23	1989-02-28	Merck & Co., Inc.	Tetrahydrocarbazole 1-alkanoic acids, pharmaceutical compositions and use
US4940719A (en) *	1986-03-27	1990-07-10	Merck Frosst Canada, Inc.	Tetrahydrocarbazole esters, pharmaceutical compositions and use
US4775680A (en) *	1987-07-21	1988-10-04	Merck & Co., Inc.	Cyclohept[b]indolealkanoic acids, pharmaceutical compositions and use
FI94339C (fi)	1989-07-21	1995-08-25	Warner Lambert Co	Menetelmä farmaseuttisesti käyttökelpoisen /R-(R,R)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
JP2648897B2 (ja)	1991-07-01	1997-09-03	塩野義製薬株式会社	ピリミジン誘導体
US5190972A (en) *	1992-01-27	1993-03-02	The University Of Melbourne	Method of combatting cyclosporine organ toxicity with prostaglandin analogs
US5631365A (en)	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
AU5787996A (en) *	1995-04-19	1996-11-07	Lipoprotein Technologies, Inc.	Compositions, kits, and methods for administration of antilipemic and anti-platelet aggregation drugs
PT877750E (pt)	1995-10-31	2002-09-30	Schering Corp	2-azetidinonas substituidas por acucar uteis como agentes hipocolesterolemiantes
AU7472896A (en)	1995-11-02	1997-05-22	Schering Corporation	Process for preparing 1-(4-fluorophenyl)-3(r)-(3(s)-hydroxy-3-({phenyl or 4-fluorophenyl})-propyl)-4(s)-(4-hydroxyphenyl)-2-azetidinon
DK0814782T3 (da)	1995-12-22	2002-12-16	Nissan Chemical Ind Ltd	Farmaceutisk præparat stabiliseret med et basisk middel
US5739321A (en)	1996-05-31	1998-04-14	Schering Corporation	3-hydroxy γ-lactone based enantionselective synthesis of azetidinones
US5886171A (en)	1996-05-31	1999-03-23	Schering Corporation	3-hydroxy gamma-lactone based enantioselective synthesis of azetidinones
US5756470A (en)	1996-10-29	1998-05-26	Schering Corporation	Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
US20010006644A1 (en) *	1997-07-31	2001-07-05	David J. Bova	Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
US6469035B1 (en) *	1997-07-31	2002-10-22	Eugenio A. Cefali	Methods of pretreating hyperlipidemic individuals with a flush inhibiting agent prior to the start of single daily dose nicotinic acid therapy to reduce flushing provoked by nicotinic acid
EP1017390B1 (en) *	1997-07-31	2007-04-18	Kos Life Sciences, Inc.	Coated tablet comprising nicotinic acid or a compound metabolized to nicotinic acid in an extended release form, and a coating containing an hmg-coa reductase inhibitor in an immediate release form
CA2307068C (en) *	1997-10-27	2007-04-10	Dr. Reddy's Laboratories Limited	Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them
US6133001A (en)	1998-02-23	2000-10-17	Schering Corporation	Stereoselective microbial reduction for the preparation of 1-(4-fluorophenyl)-3(R)-[3(S)-Hydroxy-3-(4-fluorophenyl)propyl)]-4(S)-(4 -hydroxyphenyl)-2-azetidinone
US5919672A (en)	1998-10-02	1999-07-06	Schering Corporation	Resolution of trans-2-(alkoxycarbonylethyl)-lactams useful in the synthesis of 1-(4-fluoro-phenyl)-3(R)- (S)-hydroxy-3-(4-fluorophenyl)-propyl!-4(S)-(4-hydroxyphenyl)-2-azetidinone
CA2353981C (en)	1998-12-07	2005-04-26	Schering Corporation	Process for the synthesis of azetidinones
DE69911058T2 (de)	1998-12-23	2004-06-03	G.D. Searle Llc, Chicago	Kombinationen einem ibat inhibitor und einem mtp inhibitor für kardiovaskuläre indikationen
JP3679715B2 (ja)	1999-04-05	2005-08-03	シェーリングコーポレイション	１−（４−フルオロフェニル）−３（ｒ）−［３（ｓ）−ヒドロキシ−３−（４−フルオロフェニル）プロピル）］−４（ｓ）−（４−ヒドロキシフェニル）−２−アゼチジノンの調製のための立体選択的微生物還元
AU4343500A (en)	1999-04-16	2000-11-02	Schering Corporation	Use of azetidinone compounds
IT1306141B1 (it) *	1999-05-17	2001-05-30	Giampiero Valletta	Composizione per il trattamento del prurito uremico e di forme diprurito non riconducibili a lesioni organiche.
KR20030010589A (ko)	2000-03-09	2003-02-05	오노 야꾸힝 고교 가부시키가이샤	인돌 유도체, 그 제조 방법 및 용도
US20010047027A1 (en) *	2000-04-12	2001-11-29	Marc Labelle	Prostaglandin D2 receptor antagonists
JP2002008186A (ja) *	2000-06-23	2002-01-11	Mitsubishi Heavy Ind Ltd	車種識別装置
US6410583B1 (en) *	2000-07-25	2002-06-25	Merck Frosst Canada & Co.	Cyclopentanoindoles, compositions containing such compounds and methods of treatment
JP3889563B2 (ja) *	2000-09-13	2007-03-07	三洋電機株式会社	映像信号処理回路
EP1377834A2 (en)	2001-04-11	2004-01-07	Glaxo Group Limited	Medicaments which are modulators of hm74 and/or hm74a activity
DE60215000T2 (de) *	2001-05-23	2007-08-09	Merck Frosst Canada & Co, Kirkland	Dihydropyrroloil[1,2-a]indol- und Tetrahydropyridol[1,2-a]indol-Derivate als Prostaglandin-D2-Rezeptor-Antagonisten
EP1424335A4 (en)	2001-09-07	2005-11-16	Ono Pharmaceutical Co	INDOLE DERIVATIVES
AR038136A1 (es) *	2002-01-24	2004-12-29	Merck Frosst Canada Inc	Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento
CN100378083C (zh) *	2002-03-19	2008-04-02	小野药品工业株式会社	羧酸化合物和含有所述化合物作为活性成分的药物制剂
CN100402026C (zh) *	2002-06-03	2008-07-16	诺瓦提斯公司	取代的氰基吡咯烷和含有它们的组合制剂用于治疗高脂血症和相关疾病的用途
US7019022B2 (en) *	2003-12-15	2006-03-28	Merck Frosst Canada & Co.	Substituted tetrahydrocarbazole and cyclopentanoindole derivatives
JP4129960B2 (ja) *	2005-07-01	2008-08-06	タキゲン製造株式会社	ステー

2004
- 2004-05-05 AR ARP040101527A patent/AR041089A1/es unknown
- 2004-05-06 PE PE2004000463A patent/PE20050552A1/es not_active Application Discontinuation
- 2004-05-06 JO JO200454A patent/JO2564B1/en active
- 2004-05-10 MY MYPI20041729A patent/MY140639A/en unknown
- 2004-05-13 JP JP2006515355A patent/JP4637833B2/ja not_active Expired - Fee Related
- 2004-05-13 KR KR1020077029888A patent/KR100960749B1/ko not_active Expired - Fee Related
- 2004-05-13 PL PL04785539T patent/PL1624871T3/pl unknown
- 2004-05-13 UA UAA200512018A patent/UA89615C2/ru unknown
- 2004-05-13 EP EP10182413A patent/EP2286816A1/en not_active Withdrawn
- 2004-05-13 CA CA2525772A patent/CA2525772C/en not_active Expired - Fee Related
- 2004-05-13 PL PL09163448T patent/PL2116244T3/pl unknown
- 2004-05-13 NZ NZ572515A patent/NZ572515A/en not_active IP Right Cessation
- 2004-05-13 SG SG200708456-9A patent/SG153667A1/en unknown
- 2004-05-13 RS RS20120499A patent/RS20120499A1/sr unknown
- 2004-05-13 KR KR1020057021795A patent/KR100806008B1/ko not_active Expired - Lifetime
- 2004-05-13 RS YU20050777A patent/RS52731B/sr unknown
- 2004-05-13 SI SI200431951T patent/SI2116244T1/sl unknown
- 2004-05-13 CN CN2008101690579A patent/CN101559227B/zh not_active Expired - Fee Related
- 2004-05-13 ES ES04785539T patent/ES2328148T3/es not_active Expired - Lifetime
- 2004-05-13 AU AU2004240597A patent/AU2004240597B2/en not_active Ceased
- 2004-05-13 BR BRPI0410273-8A patent/BRPI0410273A/pt not_active IP Right Cessation
- 2004-05-13 ME MEP-601/08A patent/MEP60108A/xx unknown
- 2004-05-13 EA EA200501817A patent/EA009744B1/ru not_active IP Right Cessation
- 2004-05-13 DE DE602004022036T patent/DE602004022036D1/de not_active Expired - Lifetime
- 2004-05-13 GE GEAP200410277A patent/GEP20105025B/en unknown
- 2004-05-13 CN CNB2004800128531A patent/CN100441184C/zh not_active Expired - Fee Related
- 2004-05-13 EA EA200702674A patent/EA011895B1/ru not_active IP Right Cessation
- 2004-05-13 EP EP04785539A patent/EP1624871B1/en not_active Expired - Lifetime
- 2004-05-13 MX MXPA05012272A patent/MXPA05012272A/es active IP Right Grant
- 2004-05-13 PT PT04785539T patent/PT1624871E/pt unknown
- 2004-05-13 EP EP09163448A patent/EP2116244B1/en not_active Expired - Lifetime
- 2004-05-13 US US10/844,773 patent/US20040229844A1/en not_active Abandoned
- 2004-05-13 SI SI200431221T patent/SI1624871T1/sl unknown
- 2004-05-13 GT GT200400098A patent/GT200400098A/es unknown
- 2004-05-13 HR HR20090424T patent/HRP20090424T1/xx unknown
- 2004-05-13 WO PCT/US2004/014980 patent/WO2004103370A1/en not_active Ceased
- 2004-05-13 DK DK09163448.5T patent/DK2116244T3/da active
- 2004-05-13 GE GEAP20049114A patent/GEP20084569B/en unknown
- 2004-05-13 CN CN2012100149106A patent/CN102526735A/zh active Pending
- 2004-05-13 DK DK04785539T patent/DK1624871T3/da active
- 2004-05-13 ES ES09163448T patent/ES2392743T3/es not_active Expired - Lifetime
- 2004-05-13 NZ NZ543399A patent/NZ543399A/en not_active IP Right Cessation
- 2004-05-13 RS RS20120498A patent/RS20120498A1/sr unknown
- 2004-05-13 PT PT09163448T patent/PT2116244E/pt unknown
- 2004-05-14 HN HN2004000171A patent/HN2004000171A/es unknown
- 2004-05-14 PA PA20048603201A patent/PA8603201A1/es unknown
- 2004-05-14 TW TW096125297A patent/TWI341199B/zh not_active IP Right Cessation
- 2004-05-14 CL CL200401056A patent/CL2004001056A1/es unknown
- 2004-05-14 TW TW093113730A patent/TWI334354B/zh not_active IP Right Cessation
- 2004-05-14 DO DO2004000907A patent/DOP2004000907A/es unknown
2005
- 2005-10-13 ZA ZA200508288A patent/ZA200508288B/xx unknown
- 2005-10-13 IS IS8071A patent/IS2708B/is unknown
- 2005-10-19 CR CR8047A patent/CR8047A/es unknown
- 2005-11-09 MA MA28589A patent/MA27835A1/fr unknown
- 2005-11-10 CO CO05114676A patent/CO5630034A2/es active IP Right Grant
- 2005-11-11 EC EC2005006156A patent/ECSP056156A/es unknown
- 2005-11-14 TN TNP2005000290A patent/TNSN05290A1/en unknown
- 2005-11-14 IL IL171962A patent/IL171962A/en not_active IP Right Cessation
- 2005-12-14 NO NO20055957A patent/NO20055957L/no not_active Application Discontinuation
2008
- 2008-03-11 CR CR9808A patent/CR9808A/es not_active Application Discontinuation
2009
- 2009-05-21 US US12/470,049 patent/US20090233977A1/en not_active Abandoned
- 2009-10-13 CY CY20091101051T patent/CY1109476T1/el unknown
- 2009-11-30 US US12/627,787 patent/US20100076002A1/en not_active Abandoned
- 2009-12-02 JP JP2009274146A patent/JP2010077151A/ja active Pending
2011
- 2011-01-24 US US13/012,696 patent/US20110118292A1/en not_active Abandoned
- 2011-03-07 AU AU2011200986A patent/AU2011200986B2/en not_active Ceased
2012
- 2012-10-11 HR HRP20120818TT patent/HRP20120818T1/hr unknown
- 2012-11-05 CY CY20121101050T patent/CY1113342T1/el unknown

Also Published As

Publication number	Publication date
SI1624871T1 (sl)	2009-12-31
CR8047A (es)	2006-07-14
HN2004000171A (es)	2011-07-11
PT2116244E (pt)	2012-11-02
RS20120499A1 (sr)	2013-08-30
UA89615C2 (ru)	2010-02-25
EP2286816A1 (en)	2011-02-23
EA200501817A1 (ru)	2006-06-30
EA009744B1 (ru)	2008-04-28
NO20055957L (no)	2006-02-14
CO5630034A2 (es)	2006-04-28
IL171962A (en)	2012-06-28
RS20050777A (sr)	2008-04-04
US20100076002A1 (en)	2010-03-25
GT200400098A (es)	2005-03-03
RS52731B (sr)	2013-08-30
DK2116244T3 (da)	2012-11-26
TWI334354B (en)	2010-12-11
MXPA05012272A (es)	2006-05-19
TWI341199B (en)	2011-05-01
US20110118292A1 (en)	2011-05-19
TW200503757A (en)	2005-02-01
AU2004240597B2 (en)	2011-01-06
EP1624871A1 (en)	2006-02-15
CR9808A (es)	2008-07-29
MA27835A1 (fr)	2006-04-03
PL1624871T3 (pl)	2009-12-31
CY1109476T1 (el)	2014-08-13
AU2011200986A1 (en)	2011-03-31
JP2010077151A (ja)	2010-04-08
GEP20105025B (en)	2010-06-25
GEP20084569B (en)	2008-12-25
KR20060012617A (ko)	2006-02-08
PE20050552A1 (es)	2005-08-06
PL2116244T3 (pl)	2013-01-31
NZ543399A (en)	2009-02-28
TW200803844A (en)	2008-01-16
CA2525772A1 (en)	2004-12-02
CN102526735A (zh)	2012-07-04
JP4637833B2 (ja)	2011-02-23
JO2564B1 (en)	2010-11-03
CN100441184C (zh)	2008-12-10
CY1113342T1 (el)	2016-06-22
AU2011200986B2 (en)	2012-11-08
CN1787819A (zh)	2006-06-14
CL2004001056A1 (es)	2005-03-28
SI2116244T1 (sl)	2012-12-31
WO2004103370A1 (en)	2004-12-02
CA2525772C (en)	2011-03-15
US20040229844A1 (en)	2004-11-18
MEP60108A (en)	2011-05-10
PT1624871E (pt)	2009-09-07
IS2708B (is)	2011-01-15
TNSN05290A1 (en)	2007-07-10
JP2006526030A (ja)	2006-11-16
HRP20090424T1 (en)	2009-09-30
CN101559227A (zh)	2009-10-21
DK1624871T3 (da)	2009-11-16
IL171962A0 (en)	2006-04-10
AR041089A1 (es)	2005-05-04
DOP2004000907A (es)	2004-11-30
MY140639A (en)	2010-01-15
EP2116244B1 (en)	2012-08-08
ES2392743T3 (es)	2012-12-13
KR100960749B1 (ko)	2010-06-01
SG153667A1 (en)	2009-07-29
EP1624871B1 (en)	2009-07-15
ECSP056156A (es)	2006-04-19
KR100806008B1 (ko)	2008-02-26
EP2116244A1 (en)	2009-11-11
US20090233977A1 (en)	2009-09-17
EA011895B1 (ru)	2009-06-30
ZA200508288B (en)	2008-08-27
PA8603201A1 (es)	2005-02-04
NZ572515A (en)	2010-07-30
ES2328148T3 (es)	2009-11-10
HRP20120818T1 (hr)	2012-11-30
KR20080003470A (ko)	2008-01-07
AU2004240597A1 (en)	2004-12-02
RS20120498A1 (sr)	2013-08-30
DE602004022036D1 (de)	2009-08-27
CN101559227B (zh)	2012-03-21
EA200702674A1 (ru)	2008-04-28
HK1092722A1 (zh)	2007-02-16
BRPI0410273A (pt)	2006-05-16

Publication	Publication Date	Title
IS8142A (is)	2005-11-23	Læknislyf gagnleg til meðferðar á verkjum
IS8267A (is)	2006-01-26	[1,8]naftýridín-2-ón og tengd efnasambönd til notkunar við meðferð á geðklofa
IS7684A (is)	2005-02-03	Ný efnasambönd, blöndur og aðferðir til að meðhöndla bólgusjúkdóma og -ástand
EA200500098A1 (ru)	2005-08-25	Лекарственное средство и способ лечения патологического синдрома
DE502004002801D1 (de)	2007-03-15	Bohrlochbehandlungsmittel, enthaltend ethercarbonsäuren
NO20052760D0 (no)	2005-06-07	Fremgangsmate for behandling av kreft og beslektede fremgangsmater.
IS2722B (is)	2011-03-15	1, 2, 3, 4- Tetrasetin indól til meðhöndlunar á öndunarfærasjúkdómum
EP1696877A4 (en)	2010-06-09	PROCESS FOR PAIN TREATMENT
NO20043839L (no)	2004-11-12	Havbunnsbasert intervensjonssystem, fremgangsmate for og komponeter i dette
ITMO20040191A1 (it)	2004-10-23	Macchina e metodo per il trattamento extracorporeo di sangue.
IS7648A (is)	2005-01-13	Dífenýlasetídínónafleiður til að meðhöndla fituefnaskiptasjúkdóma
DK1342881T3 (da)	2006-10-23	Opskummet syrebehandlingsvæske
NO20032220D0 (no)	2003-05-15	Löfteverktöy II og fremgangsmåte for anvendelse av samme
NO20035156D0 (no)	2003-11-20	Fremgangsmåter for brönnbehandling
DE60239766D1 (de)	2011-05-26	Wärmebehandlungssystem
NO20044195L (no)	2004-10-01	Biofosfoninsyrer for behandling og prevensjon av osteoprose
ATE402167T1 (de)	2008-08-15	4-tetrazolyl-4-phenylpiperidinderivate zur schmerzbehandlung
NO20045554L (no)	2004-12-20	Fremgangsmate for behandling av diabetes
IS6077A (is)	2001-09-18	Efnasambönd og aðferðir til meðhöndlunar á asma, ofnæmi og bólgutruflunum
ATE389742T1 (de)	2008-04-15	Gewebebehandlungsmittel
IS7163A (is)	2004-02-26	Aðferðir til meðhöndlunar á lungnasjúkdómi
EP1651237A4 (en)	2008-10-01	METHODS OF TREATING DERMATOLOGICAL DISORDERS
IS8497A (is)	2006-06-02	Aðferðir og hvarfefni til að meðhöndla bólgusjúkdóma
DK1553950T3 (da)	2007-10-15	Terapeutisk behandling
IS3004B (is)	2018-09-15	Aðferð til meðhöndlunar á svefnleysi á frumstigi