IS8582A - Notkun á dýptarsíun ásamt með samfelldri afskiljun til að fá tærar ræktir af spendýrafrumum - Google Patents

Notkun á dýptarsíun ásamt með samfelldri afskiljun til að fá tærar ræktir af spendýrafrumum

Info

Publication number
IS8582A
IS8582A IS8582A IS8582A IS8582A IS 8582 A IS8582 A IS 8582A IS 8582 A IS8582 A IS 8582A IS 8582 A IS8582 A IS 8582A IS 8582 A IS8582 A IS 8582A
Authority
IS
Iceland
Prior art keywords
filtration
mammalian cells
obtain clear
clear culture
continuous
Prior art date
Application number
IS8582A
Other languages
English (en)
Inventor
Y. Pham Christine
Th÷Mmes J÷Rg
Original Assignee
Biogen Idec Ma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35784204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS8582(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Idec Ma Inc filed Critical Biogen Idec Ma Inc
Publication of IS8582A publication Critical patent/IS8582A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02Separating microorganisms from their culture media
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02Separating microorganisms from the culture medium; Concentration of biomass
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/803Physical recovery methods, e.g. chromatography, grinding

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Water Supply & Treatment (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Centrifugal Separators (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IS8582A 2004-06-21 2006-12-19 Notkun á dýptarsíun ásamt með samfelldri afskiljun til að fá tærar ræktir af spendýrafrumum IS8582A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/871,261 US7157276B2 (en) 2003-06-20 2004-06-21 Use of depth filtration in series with continuous centrifugation to clarify mammalian cell cultures
PCT/US2005/021781 WO2006007459A1 (en) 2004-06-21 2005-06-21 Use of depth filtration in series with continuous centrifugation to clarify mammalian cell cultures

Publications (1)

Publication Number Publication Date
IS8582A true IS8582A (is) 2006-12-19

Family

ID=35784204

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8582A IS8582A (is) 2004-06-21 2006-12-19 Notkun á dýptarsíun ásamt með samfelldri afskiljun til að fá tærar ræktir af spendýrafrumum

Country Status (19)

Country Link
US (2) US7157276B2 (is)
EP (1) EP1776174A4 (is)
JP (1) JP2008503218A (is)
KR (1) KR20070046818A (is)
CN (1) CN100531868C (is)
AU (1) AU2005262431A1 (is)
BR (1) BRPI0512378A (is)
CA (1) CA2572181A1 (is)
CZ (1) CZ2006822A3 (is)
EA (1) EA011353B1 (is)
GE (1) GEP20094715B (is)
IL (1) IL180173A0 (is)
IS (1) IS8582A (is)
MX (1) MXPA06014891A (is)
NO (1) NO20070386L (is)
PL (1) PL382304A1 (is)
RS (1) RS20060680A (is)
WO (1) WO2006007459A1 (is)
ZA (1) ZA200700180B (is)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7157276B2 (en) 2003-06-20 2007-01-02 Biogen Idec Inc. Use of depth filtration in series with continuous centrifugation to clarify mammalian cell cultures
US9222067B2 (en) * 2008-04-22 2015-12-29 Pneumatic Scale Corporation Single use centrifuge system for highly concentrated and/or turbid feeds
US20110184154A1 (en) * 2008-10-17 2011-07-28 Percivia Llc Cell broth clarification and host cell protein removal
EP2402288B1 (en) * 2010-07-02 2016-11-16 Alfa Laval Corporate AB Cleaning equipment for gas scrubber fluid
DK2364760T3 (da) * 2010-02-25 2014-07-28 Alfa Laval Corp Ab Rensningsudstyr til gasskrubbervæske
DK2539281T3 (da) * 2010-02-25 2016-04-18 Alfa Laval Corp Ab Rensningsudstyr til udstødningsgas og gas-scrubber-fluid og fremgangsmåde
US9427748B2 (en) * 2010-04-02 2016-08-30 Pneumatic Scale Corporation Centrifuge system and method that determines fill status through vibration sensing
WO2013043445A2 (en) * 2011-09-21 2013-03-28 Millennium Pharmaceuticals, Inc. Methods for the harvesting of cell cultures
US9556412B2 (en) 2012-04-17 2017-01-31 Regents Of The University Of Minnesota Inlet and outlet geometries for a vertical three-stream microfluidic device
US8911634B2 (en) * 2012-08-07 2014-12-16 Molecular Devices, Llc Apparatus and method for separating materials of different densities
AU2014226126B2 (en) 2013-03-08 2019-02-14 Genzyme Corporation Continuous purification of therapeutic proteins
RU2016107435A (ru) 2013-09-13 2017-10-18 Дженентек, Инк. Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты
CN120904322A (zh) 2013-09-13 2025-11-07 豪夫迈·罗氏有限公司 包含纯化的重组多肽的方法和组合物
TWI709569B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析樹脂及其用於製造方法的用途
TWI709570B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析法及製法
US20170191101A1 (en) * 2014-03-17 2017-07-06 Regeneron Pharmaceuticals, Inc. Clarification of mammalian cell culture
DK3334747T5 (da) 2015-08-13 2024-10-07 Amgen Inc Ladet dybdefiltrering af antigenbindende proteiner
EP3436594A1 (en) * 2016-03-29 2019-02-06 Basf Se Process for producing a polyacrylamide solution with increased viscosity
CN108624499A (zh) * 2017-12-18 2018-10-09 佛山安普泽生物医药股份有限公司 一种哺乳动物细胞大规模生产培养方法
AU2019332764B2 (en) 2018-08-31 2025-05-29 Genzyme Corporation Sterile chromatography resin and use thereof in manufacturing processes
US20220081666A1 (en) * 2018-12-21 2022-03-17 Ichnos Sciences SA Methods of cell culture clarification
GB201904083D0 (en) 2019-03-25 2019-05-08 Ge Healthcare Bio Sciences Ab A bioreactor system
WO2021150996A1 (en) * 2020-01-24 2021-07-29 Amgen Inc. Methods for harvesting biomolecules
EP3936601A1 (en) * 2020-07-06 2022-01-12 Sartorius Stedim Biotech GmbH Clarification setup of a bioprocessing installation
KR102621026B1 (ko) * 2021-10-15 2024-01-09 에스케이바이오사이언스(주) 단백질의 정제방법
CN115466303A (zh) * 2022-09-15 2022-12-13 无锡药明生物技术股份有限公司 一种澄清处理的方法
WO2025184401A1 (en) * 2024-02-29 2025-09-04 Heliobiosys, Inc. A method for the purification of mycosporine-like amino acids from organisms for cosmetics and sunscreens

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0734750B2 (ja) * 1988-02-22 1995-04-19 三菱化学株式会社 エリスリトールの分離・回収方法
DE3831771A1 (de) * 1988-09-19 1990-03-29 Heraeus Sepatech Verfahren zum abtrennen von hochmolekularen substanzen aus fluessigen naehrmedien sowie vorrichtung zur durchfuehrung des verfahrens
JPH05232A (ja) * 1991-02-04 1993-01-08 Nitto Denko Corp 懸濁物質を含む醗酵液の処理方法
US5451660A (en) * 1993-12-13 1995-09-19 Genentech, Inc. Method for purifying polypeptides
US20040248271A1 (en) 2001-06-08 2004-12-09 Bu-Soo Park Composition for detecting peptidoglycan, and diagnostic kit detecting peptidoglycan
EP1453857B1 (en) * 2001-11-28 2014-08-13 Sandoz AG Chromatographic purification of recombinant human erythropoietin
CA2466881A1 (en) * 2001-11-28 2003-06-05 Sandoz Gmbh Cell culture process
WO2003046162A2 (en) 2001-11-28 2003-06-05 Polymun Scientific Immunbiologische Forschung Gmbh Process for the production of polypeptides in mammalian cell cultures
US7157276B2 (en) 2003-06-20 2007-01-02 Biogen Idec Inc. Use of depth filtration in series with continuous centrifugation to clarify mammalian cell cultures

Also Published As

Publication number Publication date
IL180173A0 (en) 2007-06-03
US7157276B2 (en) 2007-01-02
US7759117B2 (en) 2010-07-20
CN100531868C (zh) 2009-08-26
RS20060680A (sr) 2008-06-05
WO2006007459A1 (en) 2006-01-19
EP1776174A1 (en) 2007-04-25
EA200700094A1 (ru) 2007-04-27
MXPA06014891A (es) 2007-03-01
EA011353B1 (ru) 2009-02-27
PL382304A1 (pl) 2007-08-06
BRPI0512378A (pt) 2008-03-11
US20070267360A1 (en) 2007-11-22
NO20070386L (no) 2007-02-14
GEP20094715B (en) 2009-06-25
JP2008503218A (ja) 2008-02-07
CA2572181A1 (en) 2006-01-19
ZA200700180B (en) 2008-05-28
EP1776174A4 (en) 2007-08-15
US20050037333A1 (en) 2005-02-17
AU2005262431A1 (en) 2006-01-19
KR20070046818A (ko) 2007-05-03
CN101014402A (zh) 2007-08-08
CZ2006822A3 (cs) 2007-03-21

Similar Documents

Publication Publication Date Title
IS8582A (is) Notkun á dýptarsíun ásamt með samfelldri afskiljun til að fá tærar ræktir af spendýrafrumum
EP2108043A4 (en) NEW METHODS AND REAGENTS FOR THE PRODUCTION OF CELLS
DK1720972T3 (da) Fremgangsmåde til celledyrkning ved hjælp af fortløbende perfusion og vekslende tangentialt flow
DK2218776T3 (da) Dyreproteinfrit celledyrkningsmedie til dyrkning af celler
EP1815244A4 (en) CELL CULTURE DEVICE
DK2574677T3 (da) Fremgangsmåder til celledyrkning
DK1896572T3 (da) Fremgangsmåde til fremstilling af organotypiske cellekulturer
IS8619A (is) Ræktun mannafósturstofnfrumna
DK2464725T3 (da) Fremstilling af proteiner i glutaminfrie celledyrkningsmedier
EP1788073A4 (en) POROUS BLEACHING ELEMENT FOR CELL CULTURES AND BIOREACTOR THEREWITH, AND CULTURING METHOD THEREFOR
EP2189519A4 (en) CELL CULTURE INSTRUMENT AND CELL CUKLTURE PROCESS WITH THIS
EP2201134A4 (en) GENE EXPRESSION SIGNATURES IN ENRICHED TUMOR CELL SAMPLES
DK2573166T3 (da) Fremgangsmåder til fremstilling af T-celler til celleterapi
MA28882B1 (fr) Nouveaux derives de pyrimidine et leur utilisation comme modulateurs de ppar-alpha
DK2230311T3 (da) Bestanddele af celledyrkningsmedier produceret ud fra planteceller
ATE487245T1 (de) Rehydrierung von brennstoffzellen
EP1751180A4 (en) ENZYMES, CELLS, AND METHODS FOR LOCALLY-SPECIFIC RECOMBINATION AT ASYMMETRIC LOCATIONS
EP1771545A4 (en) Substructure for cell culture and use thereof
PL1835022T3 (pl) Sposób hodowli komórek i jego zastosowanie
DE602005024336D1 (de) Sendung von Nachbarnzellinformationen
DK1971555T3 (da) Bioreaktor og fremgangsmåde til biologisk oprensning af vand
DK1740693T3 (da) Kontinuerligt kulturapparat med bevægelig beholder tilladende udvælgelse af filter-cellevarianter
EP2041268A4 (en) APPLICATION OF THE EXPRESSION OF ANTIAPOPTOTIC GENES IN MAMMALIAN CELLS TO PERFUSION CULTURE
DE502005003027D1 (de) Elektrolysezelle zur herstellung von alkalimetall
IS8646A (is) Aðferð til að framleiða spendýrafrumur