DK1917267T3 - Krystalform af asenapinmaleat - Google Patents
Krystalform af asenapinmaleatInfo
- Publication number
- DK1917267T3 DK1917267T3 DK06725622T DK06725622T DK1917267T3 DK 1917267 T3 DK1917267 T3 DK 1917267T3 DK 06725622 T DK06725622 T DK 06725622T DK 06725622 T DK06725622 T DK 06725622T DK 1917267 T3 DK1917267 T3 DK 1917267T3
- Authority
- DK
- Denmark
- Prior art keywords
- crystal form
- asenapine maleate
- asenapine
- maleate
- crystal
- Prior art date
Links
- GMDCDXMAFMEDAG-CHHFXETESA-N (S,S)-asenapine maleate Chemical compound OC(=O)\C=C/C(O)=O.O1C2=CC=CC=C2[C@H]2CN(C)C[C@@H]2C2=CC(Cl)=CC=C21 GMDCDXMAFMEDAG-CHHFXETESA-N 0.000 title 1
- 229960001615 asenapine maleate Drugs 0.000 title 1
- 239000013078 crystal Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05102742 | 2005-04-07 | ||
| EP05102969 | 2005-04-14 | ||
| PCT/EP2006/061408 WO2006106135A1 (en) | 2005-04-07 | 2006-04-06 | Crystal form of asenapine maleate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1917267T3 true DK1917267T3 (da) | 2009-04-14 |
Family
ID=36617328
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06112332T DK1710245T3 (da) | 2005-04-07 | 2006-04-06 | Krystalform af asenapinmaleat |
| DK06725622T DK1917267T3 (da) | 2005-04-07 | 2006-04-06 | Krystalform af asenapinmaleat |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06112332T DK1710245T3 (da) | 2005-04-07 | 2006-04-06 | Krystalform af asenapinmaleat |
Country Status (31)
| Country | Link |
|---|---|
| EP (2) | EP1710245B1 (da) |
| JP (1) | JP5058151B2 (da) |
| KR (1) | KR101422843B1 (da) |
| AR (1) | AR056306A1 (da) |
| AT (2) | ATE370954T1 (da) |
| AU (1) | AU2006231617B2 (da) |
| BR (1) | BRPI0609741A8 (da) |
| CA (1) | CA2603509C (da) |
| CY (2) | CY1106902T1 (da) |
| DE (2) | DE602006000080T2 (da) |
| DK (2) | DK1710245T3 (da) |
| DO (1) | DOP2006000082A (da) |
| ES (2) | ES2293626T3 (da) |
| GT (1) | GT200600135A (da) |
| HN (1) | HN2006014095A (da) |
| HR (1) | HRP20070429T3 (da) |
| IL (1) | IL186355A (da) |
| MX (1) | MX2007012445A (da) |
| MY (1) | MY137969A (da) |
| NO (1) | NO340520B1 (da) |
| NZ (1) | NZ562124A (da) |
| PE (1) | PE20061311A1 (da) |
| PL (2) | PL1710245T3 (da) |
| PT (2) | PT1917267E (da) |
| RS (1) | RS50532B (da) |
| RU (1) | RU2405786C2 (da) |
| SI (2) | SI1917267T1 (da) |
| SV (1) | SV2006002473A (da) |
| TW (1) | TWI364423B (da) |
| UY (1) | UY29459A1 (da) |
| WO (1) | WO2006106135A1 (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2078024A1 (en) * | 2006-10-06 | 2009-07-15 | N.V. Organon | Amorphous asenapine and processes for preparing same |
| RU2012102247A (ru) * | 2009-06-24 | 2013-07-27 | Мсд Осс Б.В. | Инъекционные композиции, содержащие асенапин и способ лечения с их применением |
| WO2011159903A2 (en) * | 2010-06-18 | 2011-12-22 | Dr. Reddy's Laboratories Ltd. | Asenapine maleate |
| WO2012066565A2 (en) * | 2010-11-16 | 2012-05-24 | Cadila Healthcare Limited | Asenapine maleate amorphous and crystalline form and process for preparation thereof |
| EP2468750A1 (en) | 2010-12-13 | 2012-06-27 | Chemo Ibérica, S.A. | Polymorphic forms of asenapine maleate and processes for their preparation |
| WO2012123325A1 (en) | 2011-03-11 | 2012-09-20 | Medichem S.A. | NEW CRYSTAL FORMS OF THE SALT OF TRANS-5-CHLORO-2-METHYL-2,3,3A,12b-TETRAHYDRO-1H-DIBENZO[2,3:6,7]OXEPINO[4,5-c]PYRROLE WITH MALEIC ACID |
| ITMI20110734A1 (it) * | 2011-05-02 | 2012-11-03 | Olon Spa | Sali cristallini di asenapina |
| EP2524921A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel Crystalline Salts of Asenapine |
| EP2524919A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel crystalline salts of Asenapine with organic Di-acids and Tri-acids |
| EP2524920A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel Crystalline Asenapine Hydrochloride Salt Forms |
| US9533994B2 (en) | 2011-05-18 | 2017-01-03 | Laboratorios Lesvi S.L. | Monoclinic crystalline form of asenapine maleate with a specific particle size distribution |
| JP6014656B2 (ja) * | 2011-05-18 | 2016-10-25 | ラビラトリオス レスビ エス エレ | 化合物の多形体 |
| EP2572703A1 (en) | 2011-09-21 | 2013-03-27 | Hexal AG | Compressed oral dosage form for asenapine maleate |
| WO2013041604A1 (en) | 2011-09-21 | 2013-03-28 | Sandoz Ag | Crystal form of asenapine maleate |
| KR102013477B1 (ko) * | 2012-07-26 | 2019-08-22 | 히사미쓰 세이야꾸 가부시키가이샤 | 첩부제 |
| ITMI20121810A1 (it) | 2012-10-24 | 2014-04-25 | Chemo Iberica Sa | Poliformi di maleato di asenapina e processo per la loro preparazione |
| WO2014090386A1 (en) | 2012-12-11 | 2014-06-19 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Orally disintegrating tablet containing asenapine |
| WO2014127786A1 (en) | 2013-02-22 | 2014-08-28 | Zentiva, K.S. | Orally disintegrating pharmaceutical composition comprising asenapine |
| EP3350194A4 (en) | 2015-09-02 | 2019-04-24 | Eloxx Pharmaceuticals Ltd. | AMINO-LIKES DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF GENETIC DISEASES |
| ES2769286T3 (es) | 2016-12-20 | 2020-06-25 | Lts Lohmann Therapie Systeme Ag | Sistema terapéutico transdérmico que contiene asenapina |
| WO2018115010A1 (en) | 2016-12-20 | 2018-06-28 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene |
| ES2881783T3 (es) | 2017-06-26 | 2021-11-30 | Lts Lohmann Therapie Systeme Ag | Sistema terapéutico transdérmico que contiene asenapina y polímero de acrílico y silicona |
| CN112533593A (zh) | 2018-06-20 | 2021-03-19 | 罗曼治疗系统股份公司 | 含有阿塞那平的透皮治疗系统 |
| CA3101420A1 (en) | 2018-06-20 | 2019-12-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7605526A (nl) * | 1976-05-24 | 1977-11-28 | Akzo Nv | Nieuwe tetracyclische derivaten. |
| JP4099224B2 (ja) * | 1994-03-02 | 2008-06-11 | ナームローゼ・フエンノートチヤツプ・オルガノン | 舌下又はバッカル医薬組成物 |
| AU2418499A (en) * | 1997-12-19 | 1999-07-12 | Akzo Nobel N.V. | Org-5222 in the treatment of depression |
| TWI327915B (en) * | 2003-06-12 | 2010-08-01 | Organon Nv | Pharmaceutical composition comprising antipsychotic agent and use of the antipsychotic agent for treating patients with overweight |
-
2006
- 2006-04-06 DE DE602006000080T patent/DE602006000080T2/de not_active Expired - Lifetime
- 2006-04-06 SI SI200630190T patent/SI1917267T1/sl unknown
- 2006-04-06 DK DK06112332T patent/DK1710245T3/da active
- 2006-04-06 SI SI200630006T patent/SI1710245T1/sl unknown
- 2006-04-06 DK DK06725622T patent/DK1917267T3/da active
- 2006-04-06 PL PL06112332T patent/PL1710245T3/pl unknown
- 2006-04-06 RU RU2007141198/04A patent/RU2405786C2/ru active Protection Beyond IP Right Term
- 2006-04-06 JP JP2008504776A patent/JP5058151B2/ja not_active Expired - Lifetime
- 2006-04-06 AU AU2006231617A patent/AU2006231617B2/en not_active Expired
- 2006-04-06 SV SV2006002473A patent/SV2006002473A/es unknown
- 2006-04-06 GT GT200600135A patent/GT200600135A/es unknown
- 2006-04-06 TW TW095112187A patent/TWI364423B/zh active
- 2006-04-06 MY MYPI20061554A patent/MY137969A/en unknown
- 2006-04-06 DO DO2006P000082A patent/DOP2006000082A/es unknown
- 2006-04-06 EP EP06112332A patent/EP1710245B1/en not_active Expired - Lifetime
- 2006-04-06 AT AT06112332T patent/ATE370954T1/de active
- 2006-04-06 EP EP06725622A patent/EP1917267B1/en not_active Expired - Lifetime
- 2006-04-06 PT PT06725622T patent/PT1917267E/pt unknown
- 2006-04-06 MX MX2007012445A patent/MX2007012445A/es active IP Right Grant
- 2006-04-06 WO PCT/EP2006/061408 patent/WO2006106135A1/en not_active Ceased
- 2006-04-06 KR KR1020077025428A patent/KR101422843B1/ko not_active Expired - Lifetime
- 2006-04-06 ES ES06112332T patent/ES2293626T3/es not_active Expired - Lifetime
- 2006-04-06 NZ NZ562124A patent/NZ562124A/en unknown
- 2006-04-06 PE PE2006000377A patent/PE20061311A1/es active IP Right Grant
- 2006-04-06 RS RSP-2007/0436A patent/RS50532B/sr unknown
- 2006-04-06 DE DE602006004463T patent/DE602006004463D1/de not_active Expired - Lifetime
- 2006-04-06 AR ARP060101358A patent/AR056306A1/es not_active Application Discontinuation
- 2006-04-06 AT AT06725622T patent/ATE418556T1/de active
- 2006-04-06 PL PL06725622T patent/PL1917267T3/pl unknown
- 2006-04-06 UY UY29459A patent/UY29459A1/es not_active Application Discontinuation
- 2006-04-06 PT PT06112332T patent/PT1710245E/pt unknown
- 2006-04-06 HN HN2006014095A patent/HN2006014095A/es unknown
- 2006-04-06 CA CA2603509A patent/CA2603509C/en not_active Expired - Lifetime
- 2006-04-06 BR BRPI0609741A patent/BRPI0609741A8/pt not_active IP Right Cessation
- 2006-04-06 ES ES06725622T patent/ES2318742T3/es not_active Expired - Lifetime
-
2007
- 2007-09-19 HR HR20070429T patent/HRP20070429T3/xx unknown
- 2007-10-02 CY CY20071101258T patent/CY1106902T1/el unknown
- 2007-10-07 IL IL186355A patent/IL186355A/en active IP Right Grant
- 2007-10-10 NO NO20075142A patent/NO340520B1/no unknown
-
2009
- 2009-01-30 CY CY20091100111T patent/CY1108742T1/el unknown
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