IT1036400B - Pirimidine utilzzabili come prodotti antodiabetici ed ipolesterolici - Google Patents

Pirimidine utilzzabili come prodotti antodiabetici ed ipolesterolici

Info

Publication number
IT1036400B
IT1036400B IT68679/75A IT6867975A IT1036400B IT 1036400 B IT1036400 B IT 1036400B IT 68679/75 A IT68679/75 A IT 68679/75A IT 6867975 A IT6867975 A IT 6867975A IT 1036400 B IT1036400 B IT 1036400B
Authority
IT
Italy
Prior art keywords
hypolesterolic
pyrimidins
useable
diabetic
products
Prior art date
Application number
IT68679/75A
Other languages
English (en)
Inventor
Georges Mattioda
Rene Millischer
J M Claverie
Original Assignee
Rech Applic Scienti Soc Gen De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rech Applic Scienti Soc Gen De filed Critical Rech Applic Scienti Soc Gen De
Application granted granted Critical
Publication of IT1036400B publication Critical patent/IT1036400B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT68679/75A 1975-04-10 1975-07-01 Pirimidine utilzzabili come prodotti antodiabetici ed ipolesterolici IT1036400B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7511154A FR2306697A1 (fr) 1975-04-10 1975-04-10 Nouvelles pyrimidines utilisables comme medicaments antidiabetiques et hypocholesterolemiants

Publications (1)

Publication Number Publication Date
IT1036400B true IT1036400B (it) 1979-10-30

Family

ID=9153719

Family Applications (1)

Application Number Title Priority Date Filing Date
IT68679/75A IT1036400B (it) 1975-04-10 1975-07-01 Pirimidine utilzzabili come prodotti antodiabetici ed ipolesterolici

Country Status (12)

Country Link
US (1) US3984411A (it)
JP (1) JPS51118777A (it)
BE (1) BE829845A (it)
CA (1) CA1036597A (it)
CH (1) CH603626A5 (it)
DE (1) DE2528360A1 (it)
ES (1) ES439017A1 (it)
FR (1) FR2306697A1 (it)
GB (1) GB1502182A (it)
IT (1) IT1036400B (it)
LU (1) LU72743A1 (it)
NL (1) NL7507441A (it)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU176972B (hu) * 1977-06-13 1981-06-28 Gyogyszerkutato Intezet Sposob poluchenija novykh proizvodnykh piridazinil-gidrazona
US4648896A (en) * 1982-11-15 1987-03-10 Ciba-Geigy Corporation 2-aryl-4,6-dihalopyrimidines as antidote for protecting cultivated plants from phytotoxic damage caused by herbicides
FI895821A7 (fi) * 1988-12-07 1990-06-08 The Wellcome Foundation Ltd Farmaseuttisesti aktivisia CNS-yhdisteitä
CA2306477A1 (en) * 1997-11-05 1999-05-20 Neurosearch A/S Azaring-ether derivatives and their use as nicotinic ach receptor modulators
CN102558155A (zh) 2003-01-14 2012-07-11 阿伦纳药品公司 作为代谢调节剂的芳基和杂芳基衍生物及其所涉及的疾病如糖尿病和高血糖症的预防和治疗
WO2004076413A2 (en) * 2003-02-24 2004-09-10 Arena Pharmaceuticals, Inc. Phenyl- and pyridylpiperidine-derivatives as modulators of glucose metabolism
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
CA2441775C (en) * 2003-09-23 2004-09-28 Westport Research Inc. Container for holding a cryogenic fluid
HRP20090093T3 (en) * 2004-06-04 2009-03-31 Arena Pharmaceuticals Inc. Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
GEP20104966B (en) * 2005-09-16 2010-04-26 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
TW200811147A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
TW200811140A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
AU2008293462B2 (en) 2007-08-30 2013-08-15 Corteva Agriscience Llc 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides
CA2786994C (en) 2010-01-27 2018-01-16 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
MX2013003184A (es) 2010-09-22 2013-06-07 Arena Pharm Inc Moduladores del receptor gpr119 y el tratamiento de transtornos relacionados con el mismo.
AU2016205361C1 (en) 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
MX389242B (es) 2015-06-15 2025-03-20 Nmd Pharma As Compuestos para su uso en el tratamiento de trastornos neuromusculares
PL3310760T3 (pl) 2015-06-22 2023-03-06 Arena Pharmaceuticals, Inc. Krystaliczna sól L-argininy kwasu (R)-2-(7-(4-cyklopentylo-3-(trifluorometylo)benzyloksy)- 1,2,3,4-tetrahydrocyklo-penta[b]indol-3-ilo)octowego do zastosowania w zaburzeniach związanych z receptorem S1P1
KR20190116416A (ko) 2017-02-16 2019-10-14 아레나 파마슈티칼스, 인크. 원발 담즙성 담관염을 치료하기 위한 화합물 및 방법
US11730714B2 (en) 2017-12-14 2023-08-22 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US12440477B2 (en) 2017-12-14 2025-10-14 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US11591284B2 (en) 2017-12-14 2023-02-28 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US10385028B2 (en) 2017-12-14 2019-08-20 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US11147788B2 (en) 2017-12-14 2021-10-19 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
AU2019280822A1 (en) 2018-06-06 2021-01-07 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
US3261833A (en) * 1964-10-20 1966-07-19 Smith Kline French Lab 2,4-diamino-6-aminoalkoxy pyrimidines
GB1143167A (en) * 1967-01-25 1969-02-19 Ucb Sa Derivatives of pyrimidine

Also Published As

Publication number Publication date
JPS51118777A (en) 1976-10-18
ES439017A1 (es) 1977-06-16
CH603626A5 (it) 1978-08-31
FR2306697B1 (it) 1979-08-10
NL7507441A (nl) 1976-10-12
GB1502182A (en) 1978-02-22
CA1036597A (fr) 1978-08-15
FR2306697A1 (fr) 1976-11-05
BE829845A (fr) 1975-12-04
US3984411A (en) 1976-10-05
DE2528360A1 (de) 1976-10-21
LU72743A1 (it) 1975-10-08

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