ES439017A1 - Un procedimiento para la preparacion de nuevas piridinas. - Google Patents
Un procedimiento para la preparacion de nuevas piridinas.Info
- Publication number
- ES439017A1 ES439017A1 ES439017A ES439017A ES439017A1 ES 439017 A1 ES439017 A1 ES 439017A1 ES 439017 A ES439017 A ES 439017A ES 439017 A ES439017 A ES 439017A ES 439017 A1 ES439017 A1 ES 439017A1
- Authority
- ES
- Spain
- Prior art keywords
- pyrimidines
- compounds
- formula
- compound
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003230 pyrimidines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7511154A FR2306697A1 (fr) | 1975-04-10 | 1975-04-10 | Nouvelles pyrimidines utilisables comme medicaments antidiabetiques et hypocholesterolemiants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES439017A1 true ES439017A1 (es) | 1977-06-16 |
Family
ID=9153719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES439017A Expired ES439017A1 (es) | 1975-04-10 | 1975-06-30 | Un procedimiento para la preparacion de nuevas piridinas. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3984411A (es) |
| JP (1) | JPS51118777A (es) |
| BE (1) | BE829845A (es) |
| CA (1) | CA1036597A (es) |
| CH (1) | CH603626A5 (es) |
| DE (1) | DE2528360A1 (es) |
| ES (1) | ES439017A1 (es) |
| FR (1) | FR2306697A1 (es) |
| GB (1) | GB1502182A (es) |
| IT (1) | IT1036400B (es) |
| LU (1) | LU72743A1 (es) |
| NL (1) | NL7507441A (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU176972B (hu) * | 1977-06-13 | 1981-06-28 | Gyogyszerkutato Intezet | Sposob poluchenija novykh proizvodnykh piridazinil-gidrazona |
| US4648896A (en) * | 1982-11-15 | 1987-03-10 | Ciba-Geigy Corporation | 2-aryl-4,6-dihalopyrimidines as antidote for protecting cultivated plants from phytotoxic damage caused by herbicides |
| FI895821A7 (fi) * | 1988-12-07 | 1990-06-08 | The Wellcome Foundation Ltd | Farmaseuttisesti aktivisia CNS-yhdisteitä |
| EP1034174B1 (en) * | 1997-11-05 | 2003-08-13 | Neurosearch A/S | Azaring-ether derivatives and their use as nicotinic ach receptor modulators |
| RS20050532A (sr) | 2003-01-14 | 2007-12-31 | Arena Pharmaceuticals Inc., | Derivati 1,2,3-trisupstituisanog arila i heteroarila kao modulatori metabolizma za profilaksu i tretman poremećaja povezanih sa njim, kao što su dijebetes i hiperglikemija |
| DE602004017703D1 (de) * | 2003-02-24 | 2008-12-24 | Arena Pharm Inc | Phenyl- und pyridylpiperidinderivate als modulatoren des glucose-metabolismus |
| AR045047A1 (es) | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
| CA2441775C (en) * | 2003-09-23 | 2004-09-28 | Westport Research Inc. | Container for holding a cryogenic fluid |
| EA011671B1 (ru) * | 2004-06-04 | 2009-04-28 | Арена Фармасьютикалз, Инк. | Замещенные производные арила и гетероарила в качестве модуляторов метаболизма и для профилактики и лечения связанных с ним расстройств |
| DOP2006000010A (es) | 2005-01-10 | 2006-07-31 | Arena Pharm Inc | Procedimiento para preparar eteres aromáticos |
| MY148521A (en) * | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
| BRPI0616245A2 (pt) * | 2005-09-16 | 2011-06-14 | Arena Pharm Inc | modulador de metabolismo, seus usos, composiÇço farmaceutica compreendendo o mesmo, bem como mÉtodo para produÇço da referida composiÇço |
| TW200811147A (en) * | 2006-07-06 | 2008-03-01 | Arena Pharm Inc | Modulators of metabolism and the treatment of disorders related thereto |
| TW200811140A (en) * | 2006-07-06 | 2008-03-01 | Arena Pharm Inc | Modulators of metabolism and the treatment of disorders related thereto |
| AU2008293462B2 (en) | 2007-08-30 | 2013-08-15 | Corteva Agriscience Llc | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides |
| EP2528894A1 (en) | 2010-01-27 | 2012-12-05 | Arena Pharmaceuticals, Inc. | Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof |
| CN103221410B (zh) | 2010-09-22 | 2017-09-15 | 艾尼纳制药公司 | Gpr119受体调节剂和对与其相关的障碍的治疗 |
| CA3002540C (en) | 2015-01-06 | 2023-11-07 | Arena Pharmaceuticals, Inc. | Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor |
| KR102722949B1 (ko) | 2015-06-15 | 2024-10-28 | 엔엠디 파마 에이/에스 | 신경근 장애의 치료에 사용하기 위한 화합물 |
| JP6838744B2 (ja) | 2015-06-22 | 2021-03-03 | アリーナ ファーマシューティカルズ, インコーポレイテッド | S1P1レセプター関連障害における使用のための(R)−2−(7−(4−シクロペンチル−3−(トリフルオロメチル)ベンジルオキシ)−1,2,3,4−テトラヒドロシクロペンタ[b]インドール−3−イル)酢酸(化合物1)の結晶性L−アルギニン塩 |
| CN110520124A (zh) | 2017-02-16 | 2019-11-29 | 艾尼纳制药公司 | 用于治疗原发性胆汁性胆管炎的化合物和方法 |
| US11591284B2 (en) | 2017-12-14 | 2023-02-28 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
| US11147788B2 (en) | 2017-12-14 | 2021-10-19 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
| US12440477B2 (en) | 2017-12-14 | 2025-10-14 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
| US11730714B2 (en) | 2017-12-14 | 2023-08-22 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
| US10385028B2 (en) | 2017-12-14 | 2019-08-20 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
| JP7397011B2 (ja) | 2018-06-06 | 2023-12-12 | アリーナ ファーマシューティカルズ, インコーポレイテッド | S1p1受容体に関連する状態を治療する方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3259623A (en) * | 1963-06-14 | 1966-07-05 | Olin Mathieson | Process for preparing 2-(secondary amino)-halogenopyrimidines |
| US3261833A (en) * | 1964-10-20 | 1966-07-19 | Smith Kline French Lab | 2,4-diamino-6-aminoalkoxy pyrimidines |
| GB1143167A (en) * | 1967-01-25 | 1969-02-19 | Ucb Sa | Derivatives of pyrimidine |
-
1975
- 1975-04-10 FR FR7511154A patent/FR2306697A1/fr active Granted
- 1975-05-23 GB GB22982/75A patent/GB1502182A/en not_active Expired
- 1975-06-04 BE BE157011A patent/BE829845A/xx not_active IP Right Cessation
- 1975-06-16 LU LU72743A patent/LU72743A1/xx unknown
- 1975-06-19 CH CH800275A patent/CH603626A5/xx not_active IP Right Cessation
- 1975-06-23 NL NL7507441A patent/NL7507441A/xx not_active Application Discontinuation
- 1975-06-25 DE DE19752528360 patent/DE2528360A1/de not_active Withdrawn
- 1975-06-27 CA CA230,309A patent/CA1036597A/fr not_active Expired
- 1975-06-30 ES ES439017A patent/ES439017A1/es not_active Expired
- 1975-06-30 JP JP50080752A patent/JPS51118777A/ja active Pending
- 1975-07-01 IT IT68679/75A patent/IT1036400B/it active
- 1975-07-17 US US05/596,880 patent/US3984411A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| LU72743A1 (es) | 1975-10-08 |
| FR2306697B1 (es) | 1979-08-10 |
| JPS51118777A (en) | 1976-10-18 |
| CA1036597A (fr) | 1978-08-15 |
| CH603626A5 (es) | 1978-08-31 |
| NL7507441A (nl) | 1976-10-12 |
| DE2528360A1 (de) | 1976-10-21 |
| BE829845A (fr) | 1975-12-04 |
| US3984411A (en) | 1976-10-05 |
| IT1036400B (it) | 1979-10-30 |
| GB1502182A (en) | 1978-02-22 |
| FR2306697A1 (fr) | 1976-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |