IT1056733B - 4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione - Google Patents

4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione

Info

Publication number: IT1056733B
Authority: IT; Italy
Prior art keywords: reacting; alkyl; nr1r2; obtd; prod
Prior art date: 1973-08-22

Application number

IT2811573A

Other languages

English (en)

Inventor

E Manghisi

G Cascio

Original Assignee

Luso Farmaco Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-08-22

Filing date

1973-08-22

Publication date

1982-02-20

1973-08-22 Application filed by Luso Farmaco Inst filed Critical Luso Farmaco Inst

1973-08-22 Priority to IT2811573A priority Critical patent/IT1056733B/it

1973-10-03 Priority to US403275A priority patent/US3930008A/en

1973-10-10 Priority to AU61216/73A priority patent/AU490583B2/en

1973-10-11 Priority to CH1449973A priority patent/CH605859A5/xx

1973-10-12 Priority to GB4787573A priority patent/GB1429571A/en

1973-10-15 Priority to SE7313966A priority patent/SE391717B/xx

1973-10-15 Priority to FI3183/73A priority patent/FI57752C/fi

1973-10-15 Priority to NL7314147.A priority patent/NL161154C/xx

1973-10-15 Priority to ES419632A priority patent/ES419632A1/es

1973-10-15 Priority to NO4002/73A priority patent/NO140299C/no

1973-10-15 Priority to CA183,418A priority patent/CA1016550A/en

1973-10-16 Priority to DE19732351948 priority patent/DE2351948A1/de

1973-10-16 Priority to JP48116238A priority patent/JPS4993360A/ja

1973-10-16 Priority to DK560273AA priority patent/DK135122B/da

1973-10-16 Priority to FR7336838A priority patent/FR2202701B1/fr

1982-02-20 Application granted granted Critical

1982-02-20 Publication of IT1056733B publication Critical patent/IT1056733B/it

Links

XYVMOLOUBJBNBF-UHFFFAOYSA-N 3h-1,3-oxazol-2-one Chemical compound OC1=NC=CO1 XYVMOLOUBJBNBF-UHFFFAOYSA-N 0.000 title 1
-1 aryl isocyanate Chemical class 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
CKDWPUIZGOQOOM-UHFFFAOYSA-N Carbamyl chloride Chemical compound NC(Cl)=O CKDWPUIZGOQOOM-UHFFFAOYSA-N 0.000 abstract 1
239000004215 Carbon black (E152) Substances 0.000 abstract 1
XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
208000001953 Hypotension Diseases 0.000 abstract 1
YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
230000001387 anti-histamine Effects 0.000 abstract 1
239000003416 antiarrhythmic agent Substances 0.000 abstract 1
210000001772 blood platelet Anatomy 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
230000000994 depressogenic effect Effects 0.000 abstract 1
125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
150000002430 hydrocarbons Chemical class 0.000 abstract 1
ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
208000021822 hypotensive Diseases 0.000 abstract 1
230000001077 hypotensive effect Effects 0.000 abstract 1
125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
239000012948 isocyanate Substances 0.000 abstract 1
GRHBQAYDJPGGLF-UHFFFAOYSA-N isothiocyanic acid Chemical compound N=C=S GRHBQAYDJPGGLF-UHFFFAOYSA-N 0.000 abstract 1
125000002950 monocyclic group Chemical group 0.000 abstract 1
239000003158 myorelaxant agent Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
ZWZVWGITAAIFPS-UHFFFAOYSA-N thiophosgene Chemical compound ClC(Cl)=S ZWZVWGITAAIFPS-UHFFFAOYSA-N 0.000 abstract 1
125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IT2811573A 1972-10-16 1973-08-22 4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione IT1056733B (it)

Priority Applications (15)

Application Number	Priority Date	Filing Date	Title
IT2811573A IT1056733B (it)	1973-08-22	1973-08-22	4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione
US403275A US3930008A (en)	1972-10-16	1973-10-03	4-Aryl-5-aminoalkyl-4-oxazolin-2-ones
AU61216/73A AU490583B2 (en)		1973-10-10	4-aryl-5-aminoalkyl-4-oxazolin-2-ones
CH1449973A CH605859A5 (it)	1972-10-16	1973-10-11
GB4787573A GB1429571A (en)	1972-10-16	1973-10-12	4-aryl-5-aminoalkyl-4-oxazolin-2ones
FI3183/73A FI57752C (fi)	1972-10-16	1973-10-15	Foerfarande foer framstaellning av pao centralnervsystemet verkande 4-fenyl-5-amino-etyl-4-oxazolin-2-onderivat eller dess farmaceutiskt godtagbara salter
SE7313966A SE391717B (sv)	1972-10-16	1973-10-15	Forfarande for framstellning av 4-aryl-5-aminoalkyl-4-oxazolin-2-oner
NL7314147.A NL161154C (nl)	1972-10-16	1973-10-15	Werkwijze voor het bereiden van een farmaceutisch preparaat, dat een 4-oxazoline-2-on-derivaat bevat, gevormd preparaat en werkwijze voor het bereiden van een verbinding geschikt voor gebruik bij voornoemde werkwijze.
ES419632A ES419632A1 (es)	1972-10-16	1973-10-15	Un procedimiento para preparar una 4-amil-5-aminoguil-4-o- xazolin-2-ona.
NO4002/73A NO140299C (no)	1972-10-16	1973-10-15	Analogifremgangsmaate ved fremstilling av terapeutisk aktive 4-aryl-5-aminoalkyl-4-oksazolin-2-oner
CA183,418A CA1016550A (en)	1972-10-16	1973-10-15	4-aryl-5-aminoalkyl-4-oxazolin-2-ones
DE19732351948 DE2351948A1 (de)	1972-10-16	1973-10-16	4-aryl-5-aminoalkyl-4-oxazolin-2-one, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen
JP48116238A JPS4993360A (it)	1972-10-16	1973-10-16
DK560273AA DK135122B (da)	1972-10-16	1973-10-16	Analogifremgangsmåde til fremstilling af 4-aryl-5-aminoalkyl-4-oxazolin-2-onderivater.
FR7336838A FR2202701B1 (it)	1972-10-16	1973-10-16

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT2811573A IT1056733B (it)	1973-08-22	1973-08-22	4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione

Publications (1)

Publication Number	Publication Date
IT1056733B true IT1056733B (it)	1982-02-20

Family

ID=11222959

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT2811573A IT1056733B (it)	1972-10-16	1973-08-22	4 aril 5 aminoalohil 4 ossazolin 2 oni loro derivati e processi per la loro preparazione

Country Status (1)

Country	Link
IT (1)	IT1056733B (it)

1973
- 1973-08-22 IT IT2811573A patent/IT1056733B/it active

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