IT1062605B - Substrato cromogeno per trombine ed enzimi trombinici - Google Patents

Substrato cromogeno per trombine ed enzimi trombinici

Info

Publication number
IT1062605B
IT1062605B IT50364/76A IT5036476A IT1062605B IT 1062605 B IT1062605 B IT 1062605B IT 50364/76 A IT50364/76 A IT 50364/76A IT 5036476 A IT5036476 A IT 5036476A IT 1062605 B IT1062605 B IT 1062605B
Authority
IT
Italy
Prior art keywords
thrombinic
thrombines
enzymes
chromogenic substrate
chromogenic
Prior art date
Application number
IT50364/76A
Other languages
English (en)
Italian (it)
Original Assignee
Kabi Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Ab filed Critical Kabi Ab
Application granted granted Critical
Publication of IT1062605B publication Critical patent/IT1062605B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/30—Naphthyl amides, e.g. beta-NA, 2-NA, 4-methoxy-beta-naphthylamine, i.e. 4MNA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT50364/76A 1975-07-11 1976-07-09 Substrato cromogeno per trombine ed enzimi trombinici IT1062605B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7507975-6A SE407405B (sv) 1975-07-11 1975-07-11 Nya kromogena trombinsubstrat

Publications (1)

Publication Number Publication Date
IT1062605B true IT1062605B (it) 1984-10-20

Family

ID=20325116

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50364/76A IT1062605B (it) 1975-07-11 1976-07-09 Substrato cromogeno per trombine ed enzimi trombinici

Country Status (22)

Country Link
JP (1) JPS5224590A (cs)
AT (1) AT348686B (cs)
AU (1) AU497547B2 (cs)
BE (1) BE843970A (cs)
CA (1) CA1068261A (cs)
CH (1) CH622287A5 (cs)
CS (1) CS196314B2 (cs)
DD (1) DD128691A5 (cs)
DE (1) DE2629195C3 (cs)
DK (1) DK145799C (cs)
ES (1) ES449739A1 (cs)
FI (1) FI56525C (cs)
FR (1) FR2317280A1 (cs)
GB (1) GB1510926A (cs)
IL (1) IL49829A (cs)
IT (1) IT1062605B (cs)
NL (1) NL188355C (cs)
NO (1) NO142576C (cs)
PL (1) PL103003B1 (cs)
SE (1) SE407405B (cs)
SU (1) SU719492A3 (cs)
ZA (1) ZA763586B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5255593A (en) * 1975-10-30 1977-05-07 Ajinomoto Kk Measuring method of enzyme activity
DE2757992A1 (de) * 1977-12-24 1979-06-28 Boehringer Mannheim Gmbh Verfahren zur prothrombin-bestimmung
DE2812943C3 (de) * 1978-03-23 1981-05-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Reagens zur Bestimmung der biologischen Aktivität von Heparin im Plasma
US4289498A (en) * 1979-01-08 1981-09-15 Ortho Diagnostics, Inc. One-stage prothrombin assay and compositions useful therein
EP0018002B1 (de) * 1979-04-24 1983-02-09 Marcel Jozefonvicz Neues Bestimmungsverfahren für Proteasen und Antiproteasen
FR2471410A2 (fr) * 1979-12-17 1981-06-19 Jozefonvicz Marcel Perfectionnements apportes a un procede de dosage des proteases et des anti-proteases et notamment des proteases et antiproteases des systemes de la coagulation et du complement
DE3005540A1 (de) * 1980-02-14 1981-08-20 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und reagens zur bestimmung der biologischen aktivitaet von heparin im plasma
DK155051C (da) * 1980-05-06 1989-07-03 Pentapharm Ag Tripeptidderivater samt fremgangsmaade til kvantitativ analyse for proteolytiske enzymer under anvendelse deraf
JPS5856695A (ja) * 1981-09-28 1983-04-04 Nitto Boseki Co Ltd 新規なトロンビン測定用基質
DE3211254A1 (de) * 1982-03-26 1983-09-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zum nachweis des vorliegens einer allergie und zum spezifischen nachweis des fuer die allergie verantwortlichen allergens
DK201084A (da) * 1983-04-28 1984-10-29 Kimberly Clark Co Fremgangsmaade til bestemmelse af cathepsin b i naervaerelse af andre proteolytiske enzymer, og forbindelser til anvendelse ved fremgangsmaaden
CN101180405A (zh) 2005-05-20 2008-05-14 株式会社三菱化学药得论 酶分析方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE380257B (sv) * 1972-05-02 1975-11-03 Bofors Ab Nya diagnostiskt verksamma substrat med hog specificitet till trombin och andra proteolytiska enzymer av typen peptidyl-peptid-hydrolaser
SE380258B (sv) * 1972-05-02 1975-11-03 Bofors Ab Nya diagnostiskt verksamma substrat med hog specificitet till trypsin och andra enzymer av typen peptidyl-peptid-hydrolaser

Also Published As

Publication number Publication date
CH622287A5 (en) 1981-03-31
DE2629195A1 (de) 1977-01-13
SE407405B (sv) 1979-03-26
FI762010A7 (cs) 1977-01-12
DE2629195B2 (de) 1980-01-10
AU497547B2 (en) 1978-12-14
JPS5615239B2 (cs) 1981-04-09
SU719492A3 (ru) 1980-02-29
DD128691A5 (de) 1977-12-07
IL49829A (en) 1978-12-17
NL188355B (nl) 1992-01-02
JPS5224590A (en) 1977-02-24
FR2317280B1 (cs) 1980-05-16
IL49829A0 (en) 1976-08-31
SE7507975L (sv) 1977-01-12
FI56525C (fi) 1980-02-11
GB1510926A (en) 1978-05-17
AT348686B (de) 1979-02-26
AU1530576A (en) 1978-01-05
FR2317280A1 (fr) 1977-02-04
CS196314B2 (en) 1980-03-31
ES449739A1 (es) 1978-01-16
DK312676A (da) 1977-01-12
NL7607104A (nl) 1977-01-13
CA1068261A (en) 1979-12-18
DE2629195C3 (de) 1983-11-17
FI56525B (fi) 1979-10-31
DK145799B (da) 1983-03-07
NL188355C (nl) 1992-06-01
DK145799C (da) 1983-08-29
NO762407L (cs) 1977-01-12
NO142576B (no) 1980-06-02
ATA463976A (de) 1978-07-15
PL103003B1 (pl) 1979-05-31
ZA763586B (en) 1977-05-25
NO142576C (no) 1980-09-10
BE843970A (fr) 1976-11-03

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940726