IT1107880B - Procedimento per la preparazione degli acidi 2 aril propionici mediante copulazione diretta coll impiego dei complessi degli alogenuri di magnesio - Google Patents

Procedimento per la preparazione degli acidi 2 aril propionici mediante copulazione diretta coll impiego dei complessi degli alogenuri di magnesio

Info

Publication number: IT1107880B
Authority: IT; Italy
Prior art keywords: copulation; aril; procedure; direct; preparation
Prior art date: 1977-02-16

Application number

IT67279/78A

Other languages

English (en)

Italian (it)

Other versions

IT7867279A0 (it

Original Assignee

Syntex Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-02-16

Filing date

1978-02-10

Publication date

1985-12-02

1977-12-19 Priority claimed from US05/863,290 external-priority patent/US4144397A/en

1978-02-10 Application filed by Syntex Corp filed Critical Syntex Corp

1978-02-10 Publication of IT7867279A0 publication Critical patent/IT7867279A0/it

1985-12-02 Application granted granted Critical

1985-12-02 Publication of IT1107880B publication Critical patent/IT1107880B/it

Links

-1 MAGNESIUM HALIDE Chemical class 0.000 title abstract 2
230000027326 copulation Effects 0.000 title 1
229910052749 magnesium Inorganic materials 0.000 title 1
239000011777 magnesium Substances 0.000 title 1
150000004672 propanoic acids Chemical class 0.000 title 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
UUFQTNFCRMXOAE-UHFFFAOYSA-N 1-methylmethylene Chemical compound C[CH] UUFQTNFCRMXOAE-UHFFFAOYSA-N 0.000 abstract 1
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
239000000010 aprotic solvent Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
- C07C53/19—Acids containing three or more carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/14—Monocyclic dicarboxylic acids
- C07C63/15—Monocyclic dicarboxylic acids all carboxyl groups bound to carbon atoms of the six-membered aromatic ring
- C07C63/24—1,3 - Benzenedicarboxylic acid

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IT67279/78A 1977-02-16 1978-02-10 Procedimento per la preparazione degli acidi 2 aril propionici mediante copulazione diretta coll impiego dei complessi degli alogenuri di magnesio IT1107880B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US76907077A	1977-02-16	1977-02-16
US05/863,290 US4144397A (en)	1977-02-16	1977-12-19	Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed magnesium halide complex

Publications (2)

Publication Number	Publication Date
IT7867279A0 IT7867279A0 (it)	1978-02-10
IT1107880B true IT1107880B (it)	1985-12-02

Family

ID=27118118

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT67279/78A IT1107880B (it)	1977-02-16	1978-02-10	Procedimento per la preparazione degli acidi 2 aril propionici mediante copulazione diretta coll impiego dei complessi degli alogenuri di magnesio

Country Status (18)

Country	Link
CH (3)	CH640499A5 (de)
DD (3)	DD145107A5 (de)
DK (1)	DK156898C (de)
ES (1)	ES467037A1 (de)
FI (1)	FI64571C (de)
HK (2)	HK25483A (de)
HU (2)	HU179309B (de)
IE (1)	IE46614B1 (de)
IL (1)	IL54019A (de)
IT (1)	IT1107880B (de)
MY (2)	MY8400040A (de)
NO (1)	NO145435C (de)
NZ (1)	NZ186472A (de)
PL (1)	PL108144B1 (de)
PT (1)	PT67654B (de)
SE (3)	SE430155B (de)
SU (2)	SU1003749A3 (de)
YU (3)	YU41427B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8915531D0 (en) *	1989-07-06	1989-08-23	Ass Octel	Alkaline earth,transition and lanthanide metal inorganic salt complexes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1459084A (en) *	1973-05-24	1976-12-22	Boots Co Ltd	Preparation of arylalkanoic acid

1978
- 1978-02-09 FI FI780417A patent/FI64571C/fi not_active IP Right Cessation
- 1978-02-09 HU HU78SI1618A patent/HU179309B/hu unknown
- 1978-02-09 HU HU802271A patent/HU183210B/hu unknown
- 1978-02-10 IL IL54019A patent/IL54019A/xx unknown
- 1978-02-10 IT IT67279/78A patent/IT1107880B/it active
- 1978-02-13 SE SE7801648A patent/SE430155B/sv not_active IP Right Cessation
- 1978-02-13 DK DK064578A patent/DK156898C/da not_active IP Right Cessation
- 1978-02-13 YU YU329/78A patent/YU41427B/xx unknown
- 1978-02-14 NZ NZ186472A patent/NZ186472A/xx unknown
- 1978-02-14 PT PT67654A patent/PT67654B/pt unknown
- 1978-02-14 IE IE320/78A patent/IE46614B1/en not_active IP Right Cessation
- 1978-02-15 SU SU782580499A patent/SU1003749A3/ru active
- 1978-02-15 DD DD78214577A patent/DD145107A5/de not_active IP Right Cessation
- 1978-02-15 DD DD78214578A patent/DD148212A5/de not_active IP Right Cessation
- 1978-02-15 DD DD78203717A patent/DD137099A5/de not_active IP Right Cessation
- 1978-02-15 NO NO780524A patent/NO145435C/no unknown
- 1978-02-15 CH CH167578A patent/CH640499A5/de not_active IP Right Cessation
- 1978-02-16 ES ES467037A patent/ES467037A1/es not_active Expired
- 1978-02-16 PL PL1978204667A patent/PL108144B1/pl unknown
- 1978-10-11 SU SU782672198A patent/SU963462A3/ru active
1982
- 1982-03-09 SE SE8201459A patent/SE453094B/sv not_active IP Right Cessation
- 1982-03-09 SE SE8201458A patent/SE453093B/sv not_active IP Right Cessation
- 1982-09-07 CH CH531782A patent/CH640498A5/de not_active IP Right Cessation
- 1982-09-07 CH CH531882A patent/CH640500A5/de not_active IP Right Cessation
1983
- 1983-03-10 YU YU587/83A patent/YU43302B/xx unknown
- 1983-03-10 YU YU588/83A patent/YU42843B/xx unknown
- 1983-08-04 HK HK254/83A patent/HK25483A/xx not_active IP Right Cessation
- 1983-08-04 HK HK253/83A patent/HK25383A/xx not_active IP Right Cessation
1984
- 1984-12-30 MY MY40/84A patent/MY8400040A/xx unknown
- 1984-12-30 MY MY39/84A patent/MY8400039A/xx unknown

Also Published As

Publication number	Publication date
MY8400040A (en)	1984-12-31
YU41427B (en)	1987-06-30
NO145435C (no)	1982-03-24
SE453093B (sv)	1988-01-11
SE8201459L (sv)	1982-03-09
SE430155B (sv)	1983-10-24
YU43302B (en)	1989-06-30
NZ186472A (en)	1979-08-31
HK25383A (en)	1983-08-12
DD148212A5 (de)	1981-05-13
FI64571C (fi)	1983-12-12
IT7867279A0 (it)	1978-02-10
PL108144B1 (pl)	1980-03-31
SE453094B (sv)	1988-01-11
CH640498A5 (en)	1984-01-13
YU58783A (en)	1983-12-31
IE46614B1 (en)	1983-08-10
SE7801648L (sv)	1978-08-17
YU58883A (en)	1983-12-31
DK156898B (da)	1989-10-16
FI780417A7 (fi)	1978-08-17
YU42843B (en)	1988-12-31
NO780524L (no)	1978-08-17
PL204667A1 (pl)	1978-12-04
IE780320L (en)	1978-08-16
MY8400039A (en)	1984-12-31
HU183210B (en)	1984-04-28
SE8201458L (sv)	1982-03-09
DD137099A5 (de)	1979-08-15
YU32978A (en)	1983-06-30
SU1003749A3 (ru)	1983-03-07
HU179309B (en)	1982-09-28
DK64578A (da)	1978-08-17
ES467037A1 (es)	1978-11-01
IL54019A0 (en)	1978-04-30
CH640499A5 (en)	1984-01-13
DK156898C (da)	1990-03-12
IL54019A (en)	1981-06-29
PT67654A (en)	1978-03-01
SU963462A3 (ru)	1982-09-30
PT67654B (en)	1979-07-19
NO145435B (no)	1981-12-14
CH640500A5 (en)	1984-01-13
DD145107A5 (de)	1980-11-19
FI64571B (fi)	1983-08-31
HK25483A (en)	1983-08-12

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970228

Publication	Publication Date	Title
IT1107880B (it)	1985-12-02	Procedimento per la preparazione degli acidi 2 aril propionici mediante copulazione diretta coll impiego dei complessi degli alogenuri di magnesio
FR2355797A1 (fr)	1978-01-20	Procede de preparation de vinylcyclopropanes substitues utilisables dans la preparation d'insecticides
Nagel et al.	1977	Synthesis of alkyl-substituted benzo [c] phenanthrenes and chrysenes by photocyclization
ES472440A1 (es)	1979-04-16	Procedimiento para fabricar derivados de 1,3-difenoxipropan -27ona.
SE7711146L (sv)	1978-04-07	Tiaprostaglandiner
ES445263A1 (es)	1977-06-01	Un procedimiento para preparar un nuevo derivado de dimer- captoetileter.
Reeve et al.	1979	Use of sulfite esters to establish stereochemistry of chiral pinacols
Zampini	1974	DERIVATIVES OF 3, 3, 3-TRIFLUOROPROPANOIC ACID AS RELATED TO THE CARBENOID CHEMISTRY OF TRIFLUORO METHYLMETHYLENES.
Levine et al.	1988	Facile Preparation of a Butane-2, 3-Dione Monoketal
Baker	1988	I. Asymmetric organic photochemistry. II. Palladium-catalyzed allylic arylation of cyclic alkenes
JPS5452024A (en)	1979-04-24	Stereospecific synthesis of optically active compounds
小林道夫	1971	Ethyl p-toluenesulfinate
JPS5673032A (en)	1981-06-17	1-halo-4-decene compound
ES459726A1 (es)	1978-04-01	Procedimiento para la obtencion de la sal 2-(6'metoxi-2'- naftil) propionato de lisina.
ES472098A1 (es)	1979-03-16	Procedimiento para la preparacion de un complejo de haloge- nuro de magnesio mixto de acido alfa-bromo propionico.
ES467249A1 (es)	1978-12-01	Un procedimiento para la obtencion de 2-(3-metil-2-furoil)- 1, 4, 5-trimetil-1, 2, 3, 6-tetrahidropiridina.
JPS56113795A (en)	1981-09-07	2'-deoxy-3',5'-di-o-acetyl-5-fluorouridine derivative, its preparation and antitumor agent containing the same
Rollinson	1980	The synthesis of Lauraceae lactones: obtusilactones, litsenolides, and mahubanolides
JPS5473772A (en)	1979-06-13	Isoxazoline-3-one derivative
FR2325696A1 (fr)	1977-04-22	Preparation perfectionnee de quinacridone en utilisant du chlorure ferrique
FI831198L (fi)	1983-04-11	2-aryl-propionsyra magnesiumhalogenidkomplex och dess framstaellningsfoerfarande
JPS5576900A (en)	1980-06-10	24-fluoro-25-hydroxycholestene or its hydroxyl-protected derivative and their preparation
FR2392012A1 (fr)	1978-12-22	Procede pour la preparation de la carbomethoxy-hydrazone de 2-formylquinoxaline-1,4-di-n-oxyde
JPS56118036A (en)	1981-09-16	Preparation of cis-olefin derivative
GB2004865A (en)	1979-04-11	Methyl-2-picolymercaptan and derivatives thereof which are useful as flavouring agents