IT1141977B - Polipeptide prodotto microbiologicamente con la sequenza di aminoacidi dell'interferone umano,dna e plasmidi che codificano per questa sequenza,microorganismi che contengono queste informazioni genetiche e processo per la loro preparazione - Google Patents

Polipeptide prodotto microbiologicamente con la sequenza di aminoacidi dell'interferone umano,dna e plasmidi che codificano per questa sequenza,microorganismi che contengono queste informazioni genetiche e processo per la loro preparazione

Info

Publication number
IT1141977B
IT1141977B IT19760/81A IT1976081A IT1141977B IT 1141977 B IT1141977 B IT 1141977B IT 19760/81 A IT19760/81 A IT 19760/81A IT 1976081 A IT1976081 A IT 1976081A IT 1141977 B IT1141977 B IT 1141977B
Authority
IT
Italy
Prior art keywords
sequence
polypeptide
human
genetic information
plasmides
Prior art date
Application number
IT19760/81A
Other languages
English (en)
Other versions
IT8119760A0 (it
Inventor
Friedrich Wengenmayer
Joachim Hilfenhaus
Ernst Ludwig Winnacker
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IT8119760A0 publication Critical patent/IT8119760A0/it
Application granted granted Critical
Publication of IT1141977B publication Critical patent/IT1141977B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT19760/81A 1980-02-16 1981-02-13 Polipeptide prodotto microbiologicamente con la sequenza di aminoacidi dell'interferone umano,dna e plasmidi che codificano per questa sequenza,microorganismi che contengono queste informazioni genetiche e processo per la loro preparazione IT1141977B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803005897 DE3005897A1 (de) 1980-02-16 1980-02-16 Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus

Publications (2)

Publication Number Publication Date
IT8119760A0 IT8119760A0 (it) 1981-02-13
IT1141977B true IT1141977B (it) 1986-10-08

Family

ID=6094832

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19760/81A IT1141977B (it) 1980-02-16 1981-02-13 Polipeptide prodotto microbiologicamente con la sequenza di aminoacidi dell'interferone umano,dna e plasmidi che codificano per questa sequenza,microorganismi che contengono queste informazioni genetiche e processo per la loro preparazione

Country Status (13)

Country Link
EP (1) EP0034307B1 (it)
JP (1) JPS56158793A (it)
AT (1) ATE26463T1 (it)
AU (1) AU6728881A (it)
BE (1) BE887529A (it)
DE (2) DE3005897A1 (it)
ES (3) ES8301502A1 (it)
FR (1) FR2478124A1 (it)
GB (1) GB2071108A (it)
IT (1) IT1141977B (it)
NL (1) NL8100718A (it)
SE (1) SE8101005L (it)
ZA (1) ZA81975B (it)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3177213D1 (de) 1980-04-03 1990-10-18 Biogen Inc Dns-sequenzen, rekombinante dns-molekuele und verfahren zur herstellung von dem menschlichen fibroblast-interferon.
EP0042246B1 (en) * 1980-06-12 1987-03-18 The Cancer Institute Of Japanese Foundation For Cancer Research Plasmid
CH651308A5 (de) * 1980-07-01 1985-09-13 Hoffmann La Roche Interferone und deren herstellung.
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
US5582824A (en) * 1981-10-19 1996-12-10 Genentech, Inc. Recombinant DES-CYS-TYR-CYS human immune interferon
JPS58110548A (ja) * 1981-12-24 1983-07-01 Asahi Chem Ind Co Ltd 新規な生理活性ペプチド
JPS58116498A (ja) * 1981-12-28 1983-07-11 Takeda Chem Ind Ltd Ｉｌ‐２をコードする新規伝令ｒｎａの製造法
US4450103A (en) * 1982-03-01 1984-05-22 Cetus Corporation Process for recovering human IFN-β from a transformed microorganism
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
US6432677B1 (en) 1982-03-08 2002-08-13 Genentech, Inc. Non-human animal interferons
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
DE3220116A1 (de) * 1982-05-28 1983-12-01 Dr. Karl Thomae Gmbh, 7950 Biberach Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides
ZA846554B (en) * 1983-09-20 1985-04-24 Hoffmann La Roche Immune interferon and method for its purification
US4855238A (en) 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
MX9203641A (es) * 1983-12-16 1992-07-01 Genentech Inc Interferones gamma recombinantes que poseen estabilidad mejorada y metodos biotecnologicos para su obtencion.
SU1364343A1 (ru) * 1984-07-13 1988-01-07 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Способ получени человеческого лейкоцитарного интерферона альфа-2
WO1998006431A2 (en) * 1996-08-16 1998-02-19 Osther Kurt B Method for treating diabetes
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
WO2008051178A2 (en) 2006-04-12 2008-05-02 Savient Pharmaceuticals, Inc. Purification of proteins with cationic surfactant
DK3321359T3 (da) 2005-04-11 2021-03-08 Horizon Pharma Rheumatology Llc Variante former af uratoxidase og anvendelse deraf
US8273561B2 (en) 2007-10-05 2012-09-25 Nuron Biotech, Inc. High pressure treatment of aggregated interferons
RU2535038C2 (ru) 2009-06-25 2014-12-10 Криэлта Фармасьютикалз ЭлЭлСи Способы и наборы для прогнозирования риска инфузионных реакций и опосредованной антителами потери ответа при терапии пэгилированной уриказой с помощью мониторинга содержания мочевой кислоты в сыворотке крови
US20200237881A1 (en) 2019-01-30 2020-07-30 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
EP3538135A4 (en) 2016-11-11 2020-07-29 Horizon Pharma Rheumatology LLC POLYTHERAPIES OF PREDNISONE AND URICASE MOLECULES AND THEIR USES
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77877C (fi) * 1979-04-20 1989-05-10 Technobiotic Ltd Foerfarande foer framstaellning och rening av human le-formig interferonprotein.
AU538665B2 (en) * 1979-10-30 1984-08-23 Juridical Foundation, Japanese Foundation For Cancer Research Human interferon dna
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
CY1346A (en) * 1980-01-08 1987-01-16 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human interferon-like polypeptides
DK33181A (da) * 1980-02-06 1981-08-07 Searle & Co Fremgangsmaade til fremstilling af et interferonlignende protein

Also Published As

Publication number Publication date
ES499261A0 (es) 1982-06-01
FR2478124A1 (fr) 1981-09-18
ES499259A0 (es) 1982-12-01
EP0034307B1 (de) 1987-04-08
AU6728881A (en) 1981-08-27
ES8301502A1 (es) 1982-12-01
DE3176088D1 (en) 1987-05-14
IT8119760A0 (it) 1981-02-13
ES8205428A1 (es) 1982-06-01
ZA81975B (en) 1982-03-31
BE887529A (fr) 1981-08-17
SE8101005L (sv) 1981-08-17
EP0034307A3 (en) 1981-11-18
DE3005897A1 (de) 1981-09-03
JPS56158793A (en) 1981-12-07
GB2071108A (en) 1981-09-16
NL8100718A (nl) 1981-09-16
EP0034307A2 (de) 1981-08-26
ES8205431A1 (es) 1982-06-01
ES499262A0 (es) 1982-06-01
ATE26463T1 (de) 1987-04-15

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