IT1155794B - Metodo per la preparazione industriale di 3,4,5-trimetossi benzaldeide e dell'alcool 3,4,5-trimetossibenzilico - Google Patents

Metodo per la preparazione industriale di 3,4,5-trimetossi benzaldeide e dell'alcool 3,4,5-trimetossibenzilico

Info

Publication number: IT1155794B
Authority: IT; Italy
Prior art keywords: ethyl; opt; benzyl alcohol; benzaldehyde; benzoic acid
Prior art date: 1978-01-27

Application number

IT4781178A

Other languages

English (en)

Italian (it)

Other versions

IT7847811A0 (it

Inventor

Witt Paolo De

Maria Ornella Tinti

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-01-27

Filing date

1978-01-27

Publication date

1987-01-28

1978-01-27 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1978-01-27 Publication of IT7847811A0 publication Critical patent/IT7847811A0/it

1978-01-27 Priority to IT4781178A priority Critical patent/IT1155794B/it

1979-01-17 Priority to NLAANVRAGE7900366,A priority patent/NL186313C/xx

1979-01-18 Priority to US06/004,447 priority patent/US4239702A/en

1979-01-18 Priority to CH47579A priority patent/CH641752A5/it

1979-01-23 Priority to BE193029A priority patent/BE873645A/fr

1979-01-24 Priority to DE19792902541 priority patent/DE2902541A1/de

1979-01-26 Priority to CA000320388A priority patent/CA1121383A/fr

1979-01-26 Priority to FR7902124A priority patent/FR2415614A1/fr

1979-01-26 Priority to LU80835A priority patent/LU80835A1/fr

1979-01-26 Priority to GB7902895A priority patent/GB2013203B/en

1979-01-26 Priority to AT0059779A priority patent/AT364808B/de

1979-01-26 Priority to AU43694/79A priority patent/AU523640B2/en

1979-01-26 Priority to SE7900715A priority patent/SE448372B/sv

1979-01-26 Priority to NO790258A priority patent/NO149956C/no

1979-01-26 Priority to DK33879A priority patent/DK33879A/da

1979-01-26 Priority to MX79101159U priority patent/MX5736E/es

1979-01-26 Priority to ES477207A priority patent/ES477207A1/es

1979-01-26 Priority to PT7969138A priority patent/PT69138A/pt

1979-01-27 Priority to JP864779A priority patent/JPS54112831A/ja

1979-01-30 Priority to IE86/79A priority patent/IE47646B1/en

1987-01-28 Application granted granted Critical

1987-01-28 Publication of IT1155794B publication Critical patent/IT1155794B/it

Links

WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 title abstract 12
HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 title abstract 4
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 title abstract 4
235000019445 benzyl alcohol Nutrition 0.000 title abstract 4
239000005711 Benzoic acid Substances 0.000 title abstract 2
235000010233 benzoic acid Nutrition 0.000 title abstract 2
238000009903 catalytic hydrogenation reaction Methods 0.000 title abstract 2
QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 title abstract 2
YOETUEMZNOLGDB-UHFFFAOYSA-N 2-methylpropyl carbonochloridate Chemical compound CC(C)COC(Cl)=O YOETUEMZNOLGDB-UHFFFAOYSA-N 0.000 title 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 title 1
OPHQOIGEOHXOGX-UHFFFAOYSA-N 3,4,5-trimethoxybenzaldehyde Chemical compound COC1=CC(C=O)=CC(OC)=C1OC OPHQOIGEOHXOGX-UHFFFAOYSA-N 0.000 abstract 2
150000001299 aldehydes Chemical class 0.000 abstract 2
150000008064 anhydrides Chemical class 0.000 abstract 2
239000002904 solvent Substances 0.000 abstract 2
WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 abstract 1
WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 abstract 1
239000001828 Gelatine Substances 0.000 abstract 1
IWYDHOAUDWTVEP-UHFFFAOYSA-N R-2-phenyl-2-hydroxyacetic acid Natural products OC(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-N 0.000 abstract 1
-1 aromatic alcohols Chemical class 0.000 abstract 1
239000005018 casein Substances 0.000 abstract 1
BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 1
235000021240 caseins Nutrition 0.000 abstract 1
229920002301 cellulose acetate Polymers 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
229930016911 cinnamic acid Natural products 0.000 abstract 1
235000013985 cinnamic acid Nutrition 0.000 abstract 1
WZHCOOQXZCIUNC-UHFFFAOYSA-N cyclandelate Chemical compound C1C(C)(C)CC(C)CC1OC(=O)C(O)C1=CC=CC=C1 WZHCOOQXZCIUNC-UHFFFAOYSA-N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000000975 dye Substances 0.000 abstract 1
RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
239000000796 flavoring agent Substances 0.000 abstract 1
235000019634 flavors Nutrition 0.000 abstract 1
229920000159 gelatin Polymers 0.000 abstract 1
235000019322 gelatine Nutrition 0.000 abstract 1
239000012442 inert solvent Substances 0.000 abstract 1
125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 abstract 1
WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 abstract 1
229960001082 trimethoprim Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
- C07C29/149—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IT4781178A 1978-01-27 1978-01-27 Metodo per la preparazione industriale di 3,4,5-trimetossi benzaldeide e dell'alcool 3,4,5-trimetossibenzilico IT1155794B (it)

Priority Applications (20)

Application Number	Priority Date	Filing Date	Title
IT4781178A IT1155794B (it)	1978-01-27	1978-01-27	Metodo per la preparazione industriale di 3,4,5-trimetossi benzaldeide e dell'alcool 3,4,5-trimetossibenzilico
NLAANVRAGE7900366,A NL186313C (nl)	1978-01-27	1979-01-17	Werkwijze voor de bereiding van benzylalcoholen en benzaldehyden.
US06/004,447 US4239702A (en)	1978-01-27	1979-01-18	Process for preparing aromatic aldehydes and alcohols
CH47579A CH641752A5 (it)	1978-01-27	1979-01-18	Procedimento per la preparazione di alcooli aromatici.
BE193029A BE873645A (fr)	1978-01-27	1979-01-23	Procede ameliore de preparation d'aldehydes et d'alcools aromatiques, en particulier de benzaldehyde, d'alcool benzylique et leurs derives
DE19792902541 DE2902541A1 (de)	1978-01-27	1979-01-24	Verbessertes verfahren zur herstellung aromatischer aldehyde und alkohole, insbesondere benzaldehyd, benzylalkohol und ihrer derivate
AT0059779A AT364808B (de)	1978-01-27	1979-01-26	Verfahren zur herstellung von benzylalkohol und substituierten benzylalkoholen
NO790258A NO149956C (no)	1978-01-27	1979-01-26	Fremgangsmaate ved fremstilling av benzylalkohol og derivater derav.
LU80835A LU80835A1 (fr)	1978-01-27	1979-01-26	Procede ameliore de preparation d'aldehydes et d'alcools aque et de leurs derives romatiques,en particulier de benzaldehyde,d'alcool benzyli
GB7902895A GB2013203B (en)	1978-01-27	1979-01-26	Process for preparing aromatic aldehydes and alcohols
CA000320388A CA1121383A (fr)	1978-01-27	1979-01-26	Procede d'obtention d'alcools et d'aldehydes aromatiques, en particulier le benzaldehyde, de benzyalcools et de leurs derives
AU43694/79A AU523640B2 (en)	1978-01-27	1979-01-26	Preparing aromatic aldehydes and alcohols
SE7900715A SE448372B (sv)	1978-01-27	1979-01-26	Forfarande for framstellning av bensylalkohol och derivat derav
FR7902124A FR2415614A1 (fr)	1978-01-27	1979-01-26	Procede de preparation d'aldehydes et alcools aromatiques, en particulier de benzaldehyde, d'alcool benzylique et de leurs derives
DK33879A DK33879A (da)	1978-01-27	1979-01-26	Fremgangsmaade til fremstilling af aromatiske aldehyder eller alkoholer
MX79101159U MX5736E (es)	1978-01-27	1979-01-26	Procedimiento para preparar alcohol bencilico y benzaldehido
ES477207A ES477207A1 (es)	1978-01-27	1979-01-26	Proceso perfeccionado para preparar alcoholes y aldeidos aromaticos.
PT7969138A PT69138A (en)	1978-01-27	1979-01-26	Improved process for preparing aromatic aldehydes and alcohols in particular benzaldehyde benzyl alcohol and derivatives thereof
JP864779A JPS54112831A (en)	1978-01-27	1979-01-27	Manufacture of aromatic alcohol and aldehyde
IE86/79A IE47646B1 (en)	1978-01-27	1979-01-30	Process for preparing aromatic aldehydes and alcohols

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT4781178A IT1155794B (it)	1978-01-27	1978-01-27	Metodo per la preparazione industriale di 3,4,5-trimetossi benzaldeide e dell'alcool 3,4,5-trimetossibenzilico

Publications (2)

Publication Number	Publication Date
IT7847811A0 IT7847811A0 (it)	1978-01-27
IT1155794B true IT1155794B (it)	1987-01-28

Family

ID=11262663

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT4781178A IT1155794B (it)	1978-01-27	1978-01-27	Metodo per la preparazione industriale di 3,4,5-trimetossi benzaldeide e dell'alcool 3,4,5-trimetossibenzilico

Country Status (3)

Country	Link
AT (1)	AT364808B (fr)
BE (1)	BE873645A (fr)
IT (1)	IT1155794B (fr)

1978
- 1978-01-27 IT IT4781178A patent/IT1155794B/it active
1979
- 1979-01-23 BE BE193029A patent/BE873645A/fr unknown
- 1979-01-26 AT AT0059779A patent/AT364808B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATA59779A (de)	1981-04-15
AT364808B (de)	1981-11-25
BE873645A (fr)	1979-05-16
IT7847811A0 (it)	1978-01-27

Publication	Publication Date	Title
KR960703866A (ko)	1996-08-31	피라졸 및 그의 유도체의 제조 방법(Process for Preparing Pyrazole and its Derivatives)
IT1155794B (it)	1987-01-28	Metodo per la preparazione industriale di 3,4,5-trimetossi benzaldeide e dell'alcool 3,4,5-trimetossibenzilico
IT1188814B (it)	1988-01-28	Procedimento migliorato per la preparazione di aldeidi e alcooli aromatici
IE39880B1 (en)	1979-01-17	Catalysts and precesses using them
GB1525908A (en)	1978-09-27	Process for the preparation of a catalyst for use in the oxidation in the vapour phase of unsaturated aldehydes to the corresponding acids
SU745366A3 (ru)	1980-06-30	Способ получени лактона циклопентанкарбоновой кислоты
ES477207A1 (es)	1979-10-16	Proceso perfeccionado para preparar alcoholes y aldeidos aromaticos.
DE69513702D1 (de)	2000-01-13	Verfahren zur Herstellung von Hydroxybenzaldehyden
FR2351932A1 (fr)	1977-12-16	Procede d'oxydation anodique de methylbenzenes
IE790087L (en)	1979-07-27	Process for preparing aromatic aldehydes
ATE33245T1 (de)	1988-04-15	Verfahren zur herstellung von aldehyden.
GB1394651A (en)	1975-05-21	Co-production of ethyl acetate and n-butyl acetate
FR2235925A1 (en)	1975-01-31	Esterification of prostaglandins - using acetals of dimethyl formamide as esterifying agent
GB1430069A (en)	1976-03-31	Esterification process
JPS5268122A (en)	1977-06-06	Preparation of unsaturated carboxylic acids
FR2229688A1 (en)	1974-12-13	Alkyl-alpha-cycnacrylate monomers prepn. - from cyanacetic acid alkyl esters and paraformaldehyde, useful as surgical adhesives
BE814110A (fr)	1974-10-24	Procede de preparation d'esters d'acide sulfonique
JPS6116256B2 (fr)	1986-04-28
SU458231A1 (ru)	1977-08-05	Способ получени гликолей
GB1182357A (en)	1970-02-25	Process for the Production of Acetic Acid
GB1460870A (en)	1977-01-06	2-vinyl-5-methyl-1,3-dioxane and its use in the preparation of butanediol and propanediol
ES438731A1 (es)	1977-06-16	Procedimiento para la obtencion simultanea de butaudiol-1, 4, butaudiol-1, 2- y 2-metilpropandiol-1, 3.
KR920006281A (ko)	1992-04-27	아세트산 및 아세트산 무수물을 동시에 제조하는 방법
GB1530447A (en)	1978-11-01	Alcohol dehydrogenation
ES8406411A3 (es)	1984-08-01	Proceso de preparacion de esteres ciclopropanocarboxilicos sustituidos