IT1171605B - Derivati di acido 4-fenil-4-ossobuten-2-oico farmacologicamente attivi e procedimento per la loro preparazione - Google Patents

Derivati di acido 4-fenil-4-ossobuten-2-oico farmacologicamente attivi e procedimento per la loro preparazione

Info

Publication number
IT1171605B
IT1171605B IT49549/81A IT4954981A IT1171605B IT 1171605 B IT1171605 B IT 1171605B IT 49549/81 A IT49549/81 A IT 49549/81A IT 4954981 A IT4954981 A IT 4954981A IT 1171605 B IT1171605 B IT 1171605B
Authority
IT
Italy
Prior art keywords
ossobuten
fenyl
procedure
preparation
acid derivatives
Prior art date
Application number
IT49549/81A
Other languages
English (en)
Other versions
IT8149549A0 (it
IT8149549A1 (it
Inventor
Mario Bianchi
Fernando Barzaghi
Original Assignee
Roussel Maestretti Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Maestretti Spa filed Critical Roussel Maestretti Spa
Publication of IT8149549A0 publication Critical patent/IT8149549A0/it
Priority to IT49549/81A priority Critical patent/IT1171605B/it
Priority to GB08230215A priority patent/GB2108500B/en
Priority to SE8205869A priority patent/SE456502B/sv
Priority to US06/435,371 priority patent/US4486429A/en
Priority to NL8204060A priority patent/NL8204060A/nl
Priority to CH6134/82A priority patent/CH655715A5/fr
Priority to LU84430A priority patent/LU84430A1/xx
Priority to CA000413878A priority patent/CA1189526A/fr
Priority to BE0/209296A priority patent/BE894767A/fr
Priority to FR8217622A priority patent/FR2534909B1/fr
Priority to DE19823239209 priority patent/DE3239209A1/de
Priority to JP57184811A priority patent/JPS5883664A/ja
Priority to AT0388782A priority patent/AT390254B/de
Publication of IT8149549A1 publication Critical patent/IT8149549A1/it
Application granted granted Critical
Publication of IT1171605B publication Critical patent/IT1171605B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT49549/81A 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico farmacologicamente attivi e procedimento per la loro preparazione IT1171605B (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT49549/81A IT1171605B (it) 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico farmacologicamente attivi e procedimento per la loro preparazione
GB08230215A GB2108500B (en) 1981-10-22 1981-10-22 Aminobenzene medicaments
SE8205869A SE456502B (sv) 1981-10-22 1982-10-15 Aminerade derivat av 4-fenyl-4-oxo-2-butensyra, nemnda derivat till anvendning som lekemedel, farmaceutiska kompositioner innehallande dessa derivat samt sett for framstellning derav
US06/435,371 US4486429A (en) 1981-10-22 1982-10-20 Amino derivatives of 4-phenyl 4-oxobuten-2-oic acid, pharmaceutical compositions containing them, and methods for preparing and therapeutically using them
LU84430A LU84430A1 (it) 1981-10-22 1982-10-21
CH6134/82A CH655715A5 (fr) 1981-10-22 1982-10-21 Derives amines de l'acide 4-phenyl 4-oxo 2-butenoique, leur preparation et medicaments les renfermant.
NL8204060A NL8204060A (nl) 1981-10-22 1982-10-21 Derivaten van 4-fenyl-4-oxo-2-buteenzuur en zouten daarvan, farmaceutische preparaten op basis daarvan, en werkwijze voor het bereiden van een en ander.
CA000413878A CA1189526A (fr) 1981-10-22 1982-10-21 Procede de preparation de nouveaux derives amines de l'acide 4-phenyl 4-oxo 2-butenoique et de leurs sels
BE0/209296A BE894767A (fr) 1981-10-22 1982-10-21 Nouveaux derives amines de l'acide 4-phenyl 4-oxo 2-butenoique, leur preparation, leur application comme medicaments et les compositions les renfermant
FR8217622A FR2534909B1 (fr) 1981-10-22 1982-10-21 Nouveaux derives amines de l'acide 4-phenyl 4-oxo 2-butenoiques, leur preparation, leur application comme medicaments et les compositions les renfermant
DE19823239209 DE3239209A1 (de) 1981-10-22 1982-10-22 Neue amino-derivate der 4-phenyl-4-oxo-2-butensaeure, deren herstellung, deren verwendung als arzneimittel und die sie enthaltenden zusammensetzungen
JP57184811A JPS5883664A (ja) 1981-10-22 1982-10-22 ４−フエニル−４−オキソ−２−ブテン酸の新アミン誘導体、それらの製造法、それらの薬剤としての使用及びこれらを含む組成物
AT0388782A AT390254B (de) 1981-10-22 1982-10-22 Verfahren zur herstellung von neuen aminderivaten der 4-phenyl-4-oxo-2-butensaeure und von deren salzen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49549/81A IT1171605B (it) 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico farmacologicamente attivi e procedimento per la loro preparazione

Publications (3)

Publication Number Publication Date
IT8149549A0 IT8149549A0 (it) 1981-10-22
IT8149549A1 IT8149549A1 (it) 1983-04-22
IT1171605B true IT1171605B (it) 1987-06-10

Family

ID=11270996

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49549/81A IT1171605B (it) 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico farmacologicamente attivi e procedimento per la loro preparazione

Country Status (13)

Country Link
US (1) US4486429A (it)
JP (1) JPS5883664A (it)
AT (1) AT390254B (it)
BE (1) BE894767A (it)
CA (1) CA1189526A (it)
CH (1) CH655715A5 (it)
DE (1) DE3239209A1 (it)
FR (1) FR2534909B1 (it)
GB (1) GB2108500B (it)
IT (1) IT1171605B (it)
LU (1) LU84430A1 (it)
NL (1) NL8204060A (it)
SE (1) SE456502B (it)

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB588108A (en) * 1944-10-23 1947-05-14 Roche Products Ltd Manufacture of bacteriostatic substances
US2532579A (en) * 1946-08-06 1950-12-05 Du Pont Pest control compositions containing beta-acyl acrylates
US2562208A (en) * 1947-04-14 1951-07-31 Schering Corp Fungistatic composition
US2555955A (en) * 1948-03-25 1951-06-05 Searle & Co Phenyl amino benzoyl alkanoic acids
US3046301A (en) * 1959-10-29 1962-07-24 Burroughs Wellcome Co Method of making chlorambucil
DE1282644B (de) * 1962-09-08 1968-11-14 Hoechst Ag Verfahren zur Herstellung von ungesaettigten ª€-Ketocarbonsaeureestern
GR37790B (el) * 1966-12-30 1969-07-15 F. Hoffmann - La Roche & Co. Aktiengesellschaft Μεθοδος δια την παρασκευην παραγωγων του αρουλακρυλικου οξεος.
DE2047806A1 (en) * 1970-09-29 1972-04-06 Dr Karl Thomae GmbH, 7950 Biberach 3-aroyl-acrylic acids - pharmaceutical intermediates prepd from acetophenones and glyoxylic acid derivs
DE2103749A1 (en) * 1971-01-27 1972-08-10 Dr. Karl Thomae GmbH, 7951 Biberach 3-acyl-acrylic acids prepn - from a ketone and glyoxylic acid (deriv)
DE2112716A1 (de) * 1971-03-17 1972-10-05 Thomae Gmbh Dr K Neue 4-(4-Biphenylyl)-4-oxobuttersaeuren,ihre Salze und ihre Ester
DE2116293A1 (de) * 1971-04-02 1972-10-19 Cassella Farbwerke Mainkur Ag, 6000 Frankfurt Ketonderivate und Verfahren zu ihrer Herstellung
DE2123246C2 (de) * 1971-05-11 1982-11-25 Basf Ag, 6700 Ludwigshafen 6-[p-(β-Phenyläthylaminoacetylamino)-phenyl]-4,5-dihydropyridazon-(3)
US3753997A (en) * 1971-06-07 1973-08-21 A Ash Trifluoromethly substituted-2,6-diphenyl-4-pyridyl carbinolamine antimalarials
US4017517A (en) * 1971-09-13 1977-04-12 Takeda Chemical Industries, Ltd. 2-(Trisubstituted benzoyl)-propionic acid and a method for the production thereof
BE788749A (fr) * 1971-09-13 1973-03-13 Takeda Chemical Industries Ltd Acide 3-(benzoyl trisubstitue)-propionique et son procede de preparation
BE795893A (fr) * 1972-02-28 1973-06-18 Unicler Derives de (methylene dioxy-3,4 phenyl)-1 dimethyl-4,4 pentene-1, leur preparation et leur application en therrapeutique
GB1392100A (en) * 1972-09-13 1975-04-23 Beecham Group Ltd Insecticides
CH591415A5 (en) * 1972-09-13 1977-09-15 Takeda Chemical Industries Ltd 3-(Tri-substd. benzoyl) propionic acids - as relaxants or spasmolytics for the gall bladder
FR2270856B1 (it) * 1974-01-17 1978-07-21 Screen
US3953463A (en) * 1974-03-06 1976-04-27 The United States Of America As Represented By The Secretary Of The Army 2-Aryl-6-trifluoromethyl-4-pyridyl-carbinolamine antimalarials
US3940404A (en) * 1974-03-06 1976-02-24 The United States Of America As Represented By The Secretary Of The Army 2-Substituted phenyl-6-trifluoromethyl-4-pyridyl-carbinolamines
IL48319A0 (en) * 1974-10-26 1975-12-31 Merck Patent Gmbh Araliphatic nitrogen compounds and a process for their preparation
JPS5536434A (en) * 1978-09-07 1980-03-14 Sankyo Co Ltd 4-phenyl-4-oxo-2-butenoic acid derivative and its preparation

Also Published As

Publication number Publication date
DE3239209A1 (de) 1983-05-05
GB2108500A (en) 1983-05-18
FR2534909B1 (fr) 1986-02-14
BE894767A (fr) 1983-04-21
SE8205869D0 (sv) 1982-10-15
ATA388782A (de) 1989-09-15
SE456502B (sv) 1988-10-10
IT8149549A0 (it) 1981-10-22
FR2534909A1 (fr) 1984-04-27
GB2108500B (en) 1985-05-15
US4486429A (en) 1984-12-04
SE8205869L (sv) 1983-04-23
IT8149549A1 (it) 1983-04-22
AT390254B (de) 1990-04-10
CA1189526A (fr) 1985-06-25
LU84430A1 (it) 1983-06-13
JPS5883664A (ja) 1983-05-19
NL8204060A (nl) 1983-05-16
CH655715A5 (fr) 1986-05-15

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19931012