IT1182168B - Procedimento per la preparazione di derivati di prednisone, e relativi prodotti intermedi - Google Patents
Procedimento per la preparazione di derivati di prednisone, e relativi prodotti intermediInfo
- Publication number
- IT1182168B IT1182168B IT47630/85A IT4763085A IT1182168B IT 1182168 B IT1182168 B IT 1182168B IT 47630/85 A IT47630/85 A IT 47630/85A IT 4763085 A IT4763085 A IT 4763085A IT 1182168 B IT1182168 B IT 1182168B
- Authority
- IT
- Italy
- Prior art keywords
- procedure
- preparation
- intermediate products
- related intermediate
- prednisone derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR848401684A FR2559156B1 (fr) | 1984-02-03 | 1984-02-03 | Procede de preparation de derives de la prednisone et produits intermediaires de ce procede |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8547630A0 IT8547630A0 (it) | 1985-02-01 |
| IT8547630A1 IT8547630A1 (it) | 1986-08-01 |
| IT1182168B true IT1182168B (it) | 1987-09-30 |
Family
ID=9300741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT47630/85A IT1182168B (it) | 1984-02-03 | 1985-02-01 | Procedimento per la preparazione di derivati di prednisone, e relativi prodotti intermedi |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4601854A (it) |
| JP (1) | JPS60237096A (it) |
| AT (1) | AT393683B (it) |
| BE (1) | BE901627A (it) |
| CA (1) | CA1225635A (it) |
| CH (1) | CH662571A5 (it) |
| DE (1) | DE3503704C2 (it) |
| FR (1) | FR2559156B1 (it) |
| GB (1) | GB2153357B (it) |
| HU (1) | HU191771B (it) |
| IT (1) | IT1182168B (it) |
| LU (1) | LU85755A1 (it) |
| NL (1) | NL194613C (it) |
| SE (1) | SE8500462L (it) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04316593A (ja) * | 1991-02-21 | 1992-11-06 | Japan Tobacco Inc | Ｄ−アロサンの製造方法 |
| CN108014117A (zh) * | 2017-05-19 | 2018-05-11 | 南开大学 | 糖皮质激素受体的小分子拮抗剂 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1158492A (en) * | 1966-02-09 | 1969-07-16 | Boots Pure Drug Co Ltd | Improvements in Acylated Steroids |
| CH490362A (de) * | 1967-04-03 | 1970-05-15 | Upjohn Co | Verfahren zur Herstellung von 20-Ketosteroidverbindungen |
| YU41412B (en) * | 1978-08-15 | 1987-04-30 | Gist Brocades Nv | Process for obtaining 17 beta-hydroxy -3-dxo-17 alpha-pregn-4-en-21-carboxylic acid |
| HU179980B (en) * | 1979-12-28 | 1983-01-28 | Gyogyszerkutato Intezet | Process for preparing substituted steroid-spiro-oxazolidinone derivatives |
| FR2493324B1 (it) * | 1980-11-05 | 1983-01-21 | Roussel Uclaf | |
| JPS5788198A (en) * | 1980-11-21 | 1982-06-01 | Mitsubishi Chem Ind Ltd | Synthetic intermediate of corticoids |
-
1984
- 1984-02-03 FR FR848401684A patent/FR2559156B1/fr not_active Expired
-
1985
- 1985-01-28 US US06/695,485 patent/US4601854A/en not_active Expired - Lifetime
- 1985-02-01 BE BE0/214432A patent/BE901627A/fr not_active IP Right Cessation
- 1985-02-01 JP JP60016711A patent/JPS60237096A/ja not_active Withdrawn
- 1985-02-01 HU HU85399A patent/HU191771B/hu not_active IP Right Cessation
- 1985-02-01 CH CH474/85A patent/CH662571A5/fr not_active IP Right Cessation
- 1985-02-01 IT IT47630/85A patent/IT1182168B/it active
- 1985-02-01 CA CA000473406A patent/CA1225635A/fr not_active Expired
- 1985-02-01 LU LU85755A patent/LU85755A1/fr unknown
- 1985-02-01 SE SE8500462A patent/SE8500462L/ not_active Application Discontinuation
- 1985-02-04 DE DE3503704A patent/DE3503704C2/de not_active Expired - Fee Related
- 1985-02-04 AT AT0031885A patent/AT393683B/de not_active IP Right Cessation
- 1985-02-04 GB GB08502765A patent/GB2153357B/en not_active Expired
- 1985-02-04 NL NL8500297A patent/NL194613C/nl not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3503704A1 (de) | 1985-08-08 |
| SE8500462L (sv) | 1985-08-04 |
| AT393683B (de) | 1991-11-25 |
| NL194613C (nl) | 2002-09-03 |
| LU85755A1 (fr) | 1985-10-22 |
| GB2153357B (en) | 1988-04-07 |
| FR2559156A1 (fr) | 1985-08-09 |
| CA1225635A (fr) | 1987-08-18 |
| HUT37630A (en) | 1986-01-23 |
| NL194613B (nl) | 2002-05-01 |
| ATA31885A (de) | 1991-05-15 |
| CH662571A5 (fr) | 1987-10-15 |
| FR2559156B1 (fr) | 1989-03-24 |
| DE3503704C2 (de) | 1994-06-30 |
| IT8547630A1 (it) | 1986-08-01 |
| US4601854A (en) | 1986-07-22 |
| SE8500462D0 (sv) | 1985-02-01 |
| JPS60237096A (ja) | 1985-11-25 |
| BE901627A (fr) | 1985-08-01 |
| GB2153357A (en) | 1985-08-21 |
| HU191771B (en) | 1987-04-28 |
| NL8500297A (nl) | 1985-09-02 |
| IT8547630A0 (it) | 1985-02-01 |
| GB8502765D0 (en) | 1985-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960206 |