IT1190143B - Eteri 5,6-epossi-7-ossabicicloeptano sostituiti utili nel trattamento di trombosi - Google Patents

Eteri 5,6-epossi-7-ossabicicloeptano sostituiti utili nel trattamento di trombosi

Info

Publication number
IT1190143B
IT1190143B IT20970/86A IT2097086A IT1190143B IT 1190143 B IT1190143 B IT 1190143B IT 20970/86 A IT20970/86 A IT 20970/86A IT 2097086 A IT2097086 A IT 2097086A IT 1190143 B IT1190143 B IT 1190143B
Authority
IT
Italy
Prior art keywords
ossabicicloeptano
epossi
thrombosis
ethers
replaced
Prior art date
Application number
IT20970/86A
Other languages
English (en)
Other versions
IT8620970A1 (it
IT8620970A0 (it
Inventor
Das Jagabandhu
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8620970A0 publication Critical patent/IT8620970A0/it
Publication of IT8620970A1 publication Critical patent/IT8620970A1/it
Application granted granted Critical
Publication of IT1190143B publication Critical patent/IT1190143B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT20970/86A 1985-06-28 1986-06-27 Eteri 5,6-epossi-7-ossabicicloeptano sostituiti utili nel trattamento di trombosi IT1190143B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/749,912 US4611006A (en) 1985-06-28 1985-06-28 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease

Publications (3)

Publication Number Publication Date
IT8620970A0 IT8620970A0 (it) 1986-06-27
IT8620970A1 IT8620970A1 (it) 1987-12-27
IT1190143B true IT1190143B (it) 1988-02-10

Family

ID=25015736

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20970/86A IT1190143B (it) 1985-06-28 1986-06-27 Eteri 5,6-epossi-7-ossabicicloeptano sostituiti utili nel trattamento di trombosi

Country Status (7)

Country Link
US (1) US4611006A (it)
JP (1) JPS6212780A (it)
CA (1) CA1249292A (it)
DE (1) DE3621560A1 (it)
FR (1) FR2584074B1 (it)
GB (2) GB8615141D0 (it)
IT (1) IT1190143B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4611005A (en) * 1985-05-21 1986-09-09 E. R. Squibb & Sons, Inc. 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs useful in the treatment of thrombotic disease
US4734426A (en) * 1986-09-24 1988-03-29 E. R. Squibb & Sons, Inc. 5,6-epoxy-7-oxabicycloheptane substituted diamide prostaglandin analogs
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN104817568B (zh) * 2015-05-11 2017-04-12 遵义医学院 5,6‑双脱氢去甲斑蝥醇衍生物及其抗肿瘤应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4073933A (en) * 1975-06-27 1978-02-14 Sumitomo Chemical Company, Limited Novel bicycloheptene derivatives
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
EP0045118B1 (en) * 1979-01-05 1984-04-04 National Research Development Corporation Intermediates for the synthesis of bicyclo (2,2,1) heptanes and bicyclo (2,2,1) hept-2z-enes
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
CA1256887A (en) * 1983-03-14 1989-07-04 Steven E. Hall 7-oxabicycloheptane substituted prostaglandin analogs

Also Published As

Publication number Publication date
GB2177398A (en) 1987-01-21
FR2584074A1 (fr) 1987-01-02
JPS6212780A (ja) 1987-01-21
GB8615141D0 (en) 1986-07-23
DE3621560A1 (de) 1987-01-02
US4611006A (en) 1986-09-09
GB8615743D0 (en) 1986-08-06
CA1249292A (en) 1989-01-24
FR2584074B1 (fr) 1988-08-19
IT8620970A1 (it) 1987-12-27
IT8620970A0 (it) 1986-06-27
GB2177398B (en) 1989-05-04

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