IT1196485B - Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica - Google Patents

Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica

Info

Publication number
IT1196485B
IT1196485B IT21112/86A IT2111286A IT1196485B IT 1196485 B IT1196485 B IT 1196485B IT 21112/86 A IT21112/86 A IT 21112/86A IT 2111286 A IT2111286 A IT 2111286A IT 1196485 B IT1196485 B IT 1196485B
Authority
IT
Italy
Prior art keywords
thiazolidin
carboxylic acid
acid derivatives
compounds
formula
Prior art date
Application number
IT21112/86A
Other languages
English (en)
Other versions
IT8621112A1 (it
IT8621112A0 (it
Inventor
Bella Davide Della
Angelo Carenzi
Dario Chiarino
Franco Bellacini
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of IT8621112A0 publication Critical patent/IT8621112A0/it
Priority to IT21112/86A priority Critical patent/IT1196485B/it
Priority to ES87201313T priority patent/ES2054654T3/es
Priority to AT87201313T priority patent/ATE87622T1/de
Priority to EP87201313A priority patent/EP0254354B1/en
Priority to DE8787201313T priority patent/DE3785104T2/de
Priority to IE187287A priority patent/IE60205B1/en
Priority to US07/072,569 priority patent/US4840936A/en
Priority to ZA875099A priority patent/ZA875099B/xx
Priority to AU75566/87A priority patent/AU609406B2/en
Priority to CA000541971A priority patent/CA1322074C/en
Priority to JP62175776A priority patent/JP2603639B2/ja
Publication of IT8621112A1 publication Critical patent/IT8621112A1/it
Application granted granted Critical
Publication of IT1196485B publication Critical patent/IT1196485B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT21112/86A 1986-07-14 1986-07-14 Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica IT1196485B (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT21112/86A IT1196485B (it) 1986-07-14 1986-07-14 Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica
ES87201313T ES2054654T3 (es) 1986-07-14 1987-07-09 Derivados farmaceuticamente utiles de acido tiazolidina-4-carboxilico.
AT87201313T ATE87622T1 (de) 1986-07-14 1987-07-09 Pharmazeutisch nuetzliche thiazolidin-4karbons|ure-derivate.
EP87201313A EP0254354B1 (en) 1986-07-14 1987-07-09 Pharmaceutically useful derivatives of thiazolidine-4-carboxylic acid
DE8787201313T DE3785104T2 (de) 1986-07-14 1987-07-09 Pharmazeutisch nuetzliche thiazolidin-4-karbonsaeure-derivate.
IE187287A IE60205B1 (en) 1986-07-14 1987-07-10 Pharmaceutically useful derivatives of thiazolidine-4-carboxylic acid
US07/072,569 US4840936A (en) 1986-07-14 1987-07-13 Pharmaceutically useful derivatives of thiazolidine-4-carboxylic acid
ZA875099A ZA875099B (en) 1986-07-14 1987-07-13 Pharmaceutically useful derivatives of thiazolidine-4-carboxylic acid
AU75566/87A AU609406B2 (en) 1986-07-14 1987-07-13 Pharmaceutically useful derivatives of thiazolidine-4-carboxylic acid
CA000541971A CA1322074C (en) 1986-07-14 1987-07-14 Pharmaceutically useful derivatives of thiazolidine-4- carboxylic acid
JP62175776A JP2603639B2 (ja) 1986-07-14 1987-07-14 チアゾリジン―4―カルボン酸化合物、その製造方法、この化合物を含有する解熱消炎鎮痛剤および虚血・リパーフュージョン症候群治療薬

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21112/86A IT1196485B (it) 1986-07-14 1986-07-14 Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica

Publications (3)

Publication Number Publication Date
IT8621112A0 IT8621112A0 (it) 1986-07-14
IT8621112A1 IT8621112A1 (it) 1988-01-14
IT1196485B true IT1196485B (it) 1988-11-16

Family

ID=11176919

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21112/86A IT1196485B (it) 1986-07-14 1986-07-14 Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica

Country Status (11)

Country Link
US (1) US4840936A (it)
EP (1) EP0254354B1 (it)
JP (1) JP2603639B2 (it)
AT (1) ATE87622T1 (it)
AU (1) AU609406B2 (it)
CA (1) CA1322074C (it)
DE (1) DE3785104T2 (it)
ES (1) ES2054654T3 (it)
IE (1) IE60205B1 (it)
IT (1) IT1196485B (it)
ZA (1) ZA875099B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1030415A (zh) * 1987-02-20 1989-01-18 山之内制药株式会社 饱和的杂环碳酰胺衍生物和它的制备方法
IT1223565B (it) * 1987-12-21 1990-09-19 Zambon Spa Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica
DE3818850A1 (de) * 1988-06-03 1989-12-07 Hoechst Ag Oligopeptide mit zyklischen prolin-analogen aminosaeuren
IT1230706B (it) * 1989-02-10 1991-10-29 Poli Ind Chimica Spa Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche.
IT1250736B (it) * 1991-08-01 1995-04-21 Zambon Spa Processo per la preparazione dell'acido 5-(2',4'-difluorofenil) salicilico in forma ii pura
DE19711052C2 (de) * 1997-03-03 1999-09-23 Hans Rommelspacher Verwendung von 2-Methyl-thiazolidin-2,4-dicarbonsäure als Mukolytikum
KR20010025470A (ko) * 2000-12-29 2001-04-06 강덕영 치아졸리딘-4-카르복실산 염의 제조방법
CN100334206C (zh) 2002-02-28 2007-08-29 三菱化学株式会社 新型脱氢酶和编码该脱氢酶的基因
CN117677386A (zh) * 2021-07-23 2024-03-08 瓦伦塔有限责任公司 具有亲溶酶体和抗病毒活性的化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2210230A1 (de) * 1972-03-03 1973-09-06 Kolmar Laboratories Verwendung bestimmter thioaether als antimikrobielle und zytostatische mittel
US4430344A (en) * 1978-04-08 1984-02-07 Santen Pharmaceutical Co., Ltd. Antihypertensive 4-thiazolidinecarboxylic acids
DE3002989A1 (de) * 1980-01-29 1981-07-30 Hoechst Ag, 6000 Frankfurt Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels
HU195492B (en) * 1984-07-27 1988-05-30 Boehringer Biochemia Srl Process for producing 2-substituted thiazolidine derivatives with antitussive and mucus regulating action and pharmaceuticals comprising these compounds as active ingredient
IT1176983B (it) * 1984-10-16 1987-08-26 Zambon Spa Dipeptidi ad attivita' farmacologica

Also Published As

Publication number Publication date
DE3785104D1 (de) 1993-05-06
JPS6323876A (ja) 1988-02-01
ZA875099B (en) 1988-04-27
IT8621112A1 (it) 1988-01-14
EP0254354A1 (en) 1988-01-27
EP0254354B1 (en) 1993-03-31
IT8621112A0 (it) 1986-07-14
ATE87622T1 (de) 1993-04-15
JP2603639B2 (ja) 1997-04-23
AU609406B2 (en) 1991-05-02
US4840936A (en) 1989-06-20
AU7556687A (en) 1988-01-21
DE3785104T2 (de) 1993-09-02
CA1322074C (en) 1993-09-07
IE60205B1 (en) 1994-06-15
IE871872L (en) 1988-01-14
ES2054654T3 (es) 1994-08-16

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