IT1202565B - Purificazione di interleuchina-1 umana ricombinante - Google Patents

Purificazione di interleuchina-1 umana ricombinante

Info

Publication number
IT1202565B
IT1202565B IT19420/87A IT1942087A IT1202565B IT 1202565 B IT1202565 B IT 1202565B IT 19420/87 A IT19420/87 A IT 19420/87A IT 1942087 A IT1942087 A IT 1942087A IT 1202565 B IT1202565 B IT 1202565B
Authority
IT
Italy
Prior art keywords
interleuchina
purification
recombinant human
recombinant
human
Prior art date
Application number
IT19420/87A
Other languages
English (en)
Other versions
IT8719420A0 (it
Inventor
Alvin Seth Stern
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IT8719420A0 publication Critical patent/IT8719420A0/it
Application granted granted Critical
Publication of IT1202565B publication Critical patent/IT1202565B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT19420/87A 1986-02-18 1987-02-18 Purificazione di interleuchina-1 umana ricombinante IT1202565B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/830,406 US5831022A (en) 1986-02-18 1986-02-18 Purification of recombinant human IL-1α

Publications (2)

Publication Number Publication Date
IT8719420A0 IT8719420A0 (it) 1987-02-18
IT1202565B true IT1202565B (it) 1989-02-09

Family

ID=25256938

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19420/87A IT1202565B (it) 1986-02-18 1987-02-18 Purificazione di interleuchina-1 umana ricombinante

Country Status (10)

Country Link
US (1) US5831022A (it)
JP (1) JP2590085B2 (it)
BE (1) BE1000636A5 (it)
CH (1) CH676008A5 (it)
DE (1) DE3704868C2 (it)
DK (1) DK171419B1 (it)
FR (1) FR2595714B1 (it)
GB (1) GB2186580B (it)
IT (1) IT1202565B (it)
NL (1) NL8700397A (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU630341B2 (en) * 1987-12-18 1992-10-29 Immunex Corporation Topical wound-healing preparations comprising interleukin-1 proteins
EP0644203A1 (en) * 1988-07-29 1995-03-22 Otsuka Pharmaceutical Co., Ltd. IL-1alpha derivatives and medicament for treating thrombocytopenia
IT1226713B (it) * 1988-08-05 1991-02-05 Eniricerche Spa Procedimento per la preparazione di interleuchina 1 beta umana ricombinante in forma omogenea.
CA2203504A1 (en) * 1994-10-24 1996-05-02 James A. Williams Vaccine and antitoxin for treatment and prevention of c. difficile disease

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4401756A (en) * 1981-04-14 1983-08-30 Immunex Corporation Process for preparing human interleukin 2
CA1341562C (en) * 1982-03-31 2007-11-27 Tadatsugu Taniguchi Gene coded for interleukin-2 polypeptide, recombinant dna carrying the said gene, a living cell line possessing the recombinant dna, and method for producing interleukin-2 using the said cell
GR79124B (it) * 1982-12-22 1984-10-02 Genentech Inc
FR2550802B1 (fr) * 1983-08-17 1986-04-11 Inst Nat Sante Rech Med Procede de production d'interleukine 1 humaine et medicaments correspondants
DK174501B1 (da) * 1983-12-23 2003-04-28 Hoffmann La Roche Fremgangsmåde til fremstilling af interleukin-2
JPS60149386A (ja) * 1984-01-17 1985-08-06 Dainippon Pharmaceut Co Ltd インタ−ロイキン１をコ−ドする伝令リボ核酸及びその調製法
JPS60197629A (ja) * 1984-03-16 1985-10-07 Chemo Sero Therapeut Res Inst ＨＢｓ抗原の精製方法
DE3419995A1 (de) * 1984-05-29 1985-12-05 Hoechst Ag, 6230 Frankfurt Gentechnologisches verfahren zur herstellung von human-interleukin-2 und mittel zur durchfuehrung dieses verfahrens
CA1340978C (en) * 1984-06-19 2000-05-02 Douglas P. Cerretti Purification, cloning and characterization of the gene for interleukin 1
JPS617296A (ja) * 1984-06-19 1986-01-13 イミユネツクス、コ−ポレ−シヨン インタ−ロイキン１の遺伝子の精製、クロ−ニング及び特性づけ
DE3432196A1 (de) * 1984-09-01 1986-03-06 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neues mechanisches aufschlussverfahren von bakterienzellen zur isolierung von rekombinant hergestellten peptiden
EP0200986B2 (en) * 1985-04-25 1998-03-11 F. Hoffmann-La Roche Ag Recombinant human interleukin-1
US4675387A (en) * 1985-07-26 1987-06-23 E. I. Du Pont De Nemours And Company Method for extracting protein with organic acid
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
US4801686A (en) * 1986-09-04 1989-01-31 Immunex Corporation Purification of recombinant interleukin-1

Also Published As

Publication number Publication date
DE3704868C2 (de) 1995-09-21
GB2186580A (en) 1987-08-19
US5831022A (en) 1998-11-03
JP2590085B2 (ja) 1997-03-12
GB8703663D0 (en) 1987-03-25
DE3704868A1 (de) 1987-08-20
DK171419B1 (da) 1996-10-21
GB2186580B (en) 1990-08-22
FR2595714A1 (fr) 1987-09-18
NL8700397A (nl) 1987-09-16
DK77387D0 (da) 1987-02-16
JPS62209097A (ja) 1987-09-14
IT8719420A0 (it) 1987-02-18
DK77387A (da) 1987-08-19
BE1000636A5 (fr) 1989-02-28
FR2595714B1 (fr) 1990-05-18
CH676008A5 (it) 1990-11-30

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970227