IT1204434B - Composizioni farmaceutiche comprendenti frammenti di acth per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoria - Google Patents
Composizioni farmaceutiche comprendenti frammenti di acth per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoriaInfo
- Publication number
- IT1204434B IT1204434B IT8619086A IT1908686A IT1204434B IT 1204434 B IT1204434 B IT 1204434B IT 8619086 A IT8619086 A IT 8619086A IT 1908686 A IT1908686 A IT 1908686A IT 1204434 B IT1204434 B IT 1204434B
- Authority
- IT
- Italy
- Prior art keywords
- respiratory
- cardiocirculatory
- insufficiency
- pharmaceutical compositions
- therapeutic treatment
- Prior art date
Links
- IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical group C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 title abstract 4
- 230000000241 respiratory effect Effects 0.000 title abstract 2
- 230000035939 shock Effects 0.000 title abstract 2
- 230000002425 cardiocirculatory effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 101800000414 Corticotropin Proteins 0.000 abstract 2
- 239000000275 Adrenocorticotropic Hormone Substances 0.000 abstract 1
- 239000000055 Corticotropin-Releasing Hormone Substances 0.000 abstract 1
- 206010021138 Hypovolaemic shock Diseases 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 229960000258 corticotropin Drugs 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 206010040560 shock Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- A61K38/35—Corticotropin [ACTH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- A61K38/34—Melanocyte stimulating hormone [MSH], e.g. alpha- or beta-melanotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/695—Corticotropin [ACTH]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8619086A IT1204434B (it) | 1986-01-15 | 1986-01-15 | Composizioni farmaceutiche comprendenti frammenti di acth per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoria |
| DE87100016T DE3786682T2 (de) | 1986-01-15 | 1987-01-02 | ACTH-Fragmente enthaltende pharmazeutische Zusammensetzungen zur Behandlung von Schockzuständen sowie von respiratorischen und Herz-Kreislauf-Insuffizienzen. |
| EP87100016A EP0232697B1 (en) | 1986-01-15 | 1987-01-02 | Pharmaceutical compositions containing acth fragments for the therapy of shock conditions and of respiratory and cardiocirculatory insufficiencies |
| AT87100016T ATE91900T1 (de) | 1986-01-15 | 1987-01-02 | Acth-fragmente enthaltende pharmazeutische zusammensetzungen zur behandlung von schockzustaenden sowie von respiratorischen und herz-kreislauf-insuffizienzen. |
| ES87100016T ES2058065T3 (es) | 1986-01-15 | 1987-01-02 | Composiciones farmaceuticas que contienen fragmentos de acth para la terapia de condiciones de shock y de insuficiencias respiratorias y cardiocirculatorias. |
| US07/000,183 US4794104A (en) | 1986-01-15 | 1987-01-02 | Pharmaceutical compositions containing ACTH fragments for the therapy of shock conditions and of respiratory and cardiocirculatory insufficiencies |
| JP62001574A JP2606835B2 (ja) | 1986-01-15 | 1987-01-07 | ショック症状及び呼吸機能障害や心臓循環機能不全を治療する為のacth断片を含有する薬学的組成物及び薬剤キット |
| ZA87246A ZA87246B (en) | 1986-01-15 | 1987-01-14 | Pharmaceutical compositions containing acth fragments for the therapy of shock conditions and of respiratory and cardiocirculatory insufficiencies |
| HK98105520A HK1006283A1 (en) | 1986-01-15 | 1998-06-17 | Pharmaceutical compositions containing acth fragments for the therapy of shock conditions and of respiratory and cardiocirculatory insufficiencies |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8619086A IT1204434B (it) | 1986-01-15 | 1986-01-15 | Composizioni farmaceutiche comprendenti frammenti di acth per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoria |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8619086A0 IT8619086A0 (it) | 1986-01-15 |
| IT1204434B true IT1204434B (it) | 1989-03-01 |
Family
ID=11154420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8619086A IT1204434B (it) | 1986-01-15 | 1986-01-15 | Composizioni farmaceutiche comprendenti frammenti di acth per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoria |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4794104A (it) |
| EP (1) | EP0232697B1 (it) |
| JP (1) | JP2606835B2 (it) |
| AT (1) | ATE91900T1 (it) |
| DE (1) | DE3786682T2 (it) |
| ES (1) | ES2058065T3 (it) |
| HK (1) | HK1006283A1 (it) |
| IT (1) | IT1204434B (it) |
| ZA (1) | ZA87246B (it) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1218472B (it) * | 1985-08-30 | 1990-04-19 | Alfio Bertolini | Composizioni farmaceutiche comprendenti acht (1-24) per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoria |
| FR2691465B1 (fr) * | 1992-05-25 | 1995-08-11 | Pf Medicament | Complexes comprenant au moins un peptide derive de l'alpha msh, peptide, microsphere, medicament et composition galenique les comprenant. |
| US20080146973A1 (en) * | 2006-12-15 | 2008-06-19 | Laerdal Medical As | System for providing feedback on chest compression in CPR |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3234201A (en) * | 1959-05-28 | 1966-02-08 | Ciba Geigy Corp | Octadecapeptides and derivatives thereof |
| CH422813A (de) * | 1960-11-17 | 1966-10-31 | Ciba Geigy | Verfahren zur Herstellung neuer Polypeptide |
| NL278010A (it) * | 1961-05-04 | 1900-01-01 | ||
| US3264280A (en) * | 1961-11-28 | 1966-08-02 | Klaus H Hofmann | Tricosapeptides and intermediates for the preparation thereof |
| NL289055A (it) * | 1963-02-15 | |||
| DE1493649A1 (de) * | 1963-08-16 | 1969-11-13 | Hoechst Ag | Verfahren zur Herstellung adrenocorticotrop wirksamer Peptide |
| CH443335A (de) * | 1964-01-31 | 1967-09-15 | Sandoz Ag | Verfahren zur Herstellung eines neuen Polypeptids |
| DE1265915B (de) * | 1964-12-12 | 1968-04-11 | Hoechst Ag | Verfahren zur Herstellung von protrahiert wirkenden ACTH-Praeparaten |
| NL6509727A (it) * | 1965-07-28 | 1967-01-30 | ||
| CH569699A5 (it) * | 1966-09-10 | 1975-11-28 | Richter Gedeon Vegyeszet | |
| CH488664A (de) * | 1967-02-09 | 1970-04-15 | Ciba Geigy | Verfahren zur Herstellung von adrenocorticotrop wirksamen Peptiden mit verlängerter Wirkung |
| GB1230472A (it) * | 1967-07-10 | 1971-05-05 | ||
| BE758206A (fr) * | 1969-10-31 | 1971-04-29 | Hoechst Ag | Peptides a activite adrenocorticotrope et medicaments qui en contiennent |
| HU167655B (it) * | 1972-08-18 | 1975-11-28 | ||
| HU167360B (it) * | 1972-08-25 | 1975-09-27 | ||
| US3915949A (en) * | 1974-02-12 | 1975-10-28 | Armour Pharma | Solid phase synthesis of ACTH |
| US4457864A (en) * | 1981-10-23 | 1984-07-03 | University Patents, Inc. | Synthetic analogues of α-melanotropin |
-
1986
- 1986-01-15 IT IT8619086A patent/IT1204434B/it active
-
1987
- 1987-01-02 US US07/000,183 patent/US4794104A/en not_active Expired - Lifetime
- 1987-01-02 AT AT87100016T patent/ATE91900T1/de not_active IP Right Cessation
- 1987-01-02 DE DE87100016T patent/DE3786682T2/de not_active Expired - Fee Related
- 1987-01-02 ES ES87100016T patent/ES2058065T3/es not_active Expired - Lifetime
- 1987-01-02 EP EP87100016A patent/EP0232697B1/en not_active Expired - Lifetime
- 1987-01-07 JP JP62001574A patent/JP2606835B2/ja not_active Expired - Lifetime
- 1987-01-14 ZA ZA87246A patent/ZA87246B/xx unknown
-
1998
- 1998-06-17 HK HK98105520A patent/HK1006283A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2606835B2 (ja) | 1997-05-07 |
| EP0232697B1 (en) | 1993-07-28 |
| EP0232697A3 (en) | 1990-05-23 |
| EP0232697A2 (en) | 1987-08-19 |
| JPS62215531A (ja) | 1987-09-22 |
| ATE91900T1 (de) | 1993-08-15 |
| ZA87246B (en) | 1987-09-30 |
| US4794104A (en) | 1988-12-27 |
| DE3786682T2 (de) | 1993-12-23 |
| IT8619086A0 (it) | 1986-01-15 |
| DE3786682D1 (de) | 1993-09-02 |
| ES2058065T3 (es) | 1994-11-01 |
| HK1006283A1 (en) | 1999-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19940128 |