IT1204948B - 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono. - Google Patents

2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.

Info

Publication number
IT1204948B
IT1204948B IT8719700A IT1970087A IT1204948B IT 1204948 B IT1204948 B IT 1204948B IT 8719700 A IT8719700 A IT 8719700A IT 1970087 A IT1970087 A IT 1970087A IT 1204948 B IT1204948 B IT 1204948B
Authority
IT
Italy
Prior art keywords
thyomethy
pyridins
substitute
preparation
pharmaceutical compositions
Prior art date
Application number
IT8719700A
Other languages
English (en)
Other versions
IT8719700A0 (it
Inventor
A Gandolfi Carmelo
Frigerio Marco
Tofanetti Odoardo
Tognella Sergio
Original Assignee
Boheringer Biochemia Robin S P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boheringer Biochemia Robin S P filed Critical Boheringer Biochemia Robin S P
Priority to IT8719700A priority Critical patent/IT1204948B/it
Publication of IT8719700A0 publication Critical patent/IT8719700A0/it
Priority to DE8888103777T priority patent/DE3873939D1/de
Priority to AT88103777T priority patent/ATE79870T1/de
Priority to EP88103777A priority patent/EP0282904B1/en
Priority to US07/167,164 priority patent/US4918087A/en
Priority to JP63058141A priority patent/JPS63243073A/ja
Application granted granted Critical
Publication of IT1204948B publication Critical patent/IT1204948B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT8719700A 1987-03-13 1987-03-13 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono. IT1204948B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT8719700A IT1204948B (it) 1987-03-13 1987-03-13 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.
DE8888103777T DE3873939D1 (de) 1987-03-13 1988-03-10 2-thiomethyl-substituierte pyridine, verfahren zu deren herstellung und diese enthaltende arzneimittel.
AT88103777T ATE79870T1 (de) 1987-03-13 1988-03-10 2-thiomethyl-substituierte pyridine, verfahren zu deren herstellung und diese enthaltende arzneimittel.
EP88103777A EP0282904B1 (en) 1987-03-13 1988-03-10 2-thiomethyl-substituted-pyridines, a method for their preparation and pharmaceutical compositions containing them
US07/167,164 US4918087A (en) 1987-03-13 1988-03-11 2-thiomethyl-substituted-pyridine and -3,5-dicarboxylates having anti-hypertensive activity
JP63058141A JPS63243073A (ja) 1987-03-13 1988-03-11 ２−チオメチル−置換ピリジン、その製造方法、及び該ピリジンを含有する薬剤組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8719700A IT1204948B (it) 1987-03-13 1987-03-13 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.

Publications (2)

Publication Number Publication Date
IT8719700A0 IT8719700A0 (it) 1987-03-13
IT1204948B true IT1204948B (it) 1989-03-10

Family

ID=11160490

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8719700A IT1204948B (it) 1987-03-13 1987-03-13 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.

Country Status (6)

Country Link
US (1) US4918087A (it)
EP (1) EP0282904B1 (it)
JP (1) JPS63243073A (it)
AT (1) ATE79870T1 (it)
DE (1) DE3873939D1 (it)
IT (1) IT1204948B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8905526D0 (en) * 1989-03-10 1989-04-19 Fujisawa Pharmaceutical Co N-containing heterocyclic compounds,processes for the preparation thereof and composition comprising the same
ES2065234B1 (es) * 1992-10-27 1995-09-01 Smithkline Beecham Corp Compuestos para tratar enfermedades relacionadas con los leucotrienos.
US5380734A (en) * 1993-04-15 1995-01-10 American Home Products Corporation N-cyanoamidine derivatives as anti-influenza agents
DE4430638A1 (de) * 1994-08-29 1996-03-07 Bayer Ag Verwendung von substituierten 4-Phenyl-6-amino-nicotinsäurederivaten als Arzneimittel
DE19532320A1 (de) * 1995-09-01 1997-03-06 Bayer Ag Verfahren zur Herstellung von optisch aktiven ortho-substituierten 4-Aryl-Dihydropyridinen
HUP0201566A3 (en) * 1999-06-14 2004-03-01 Ortho Mcneil Pharm Inc Dithiepino[6,5-b]pyridines, their preparation pharmaceutical compositions containing thereof and an apparatus for their administering
DE10115945A1 (de) * 2001-03-30 2002-10-02 Bayer Ag Substituierte 2-Carba-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3209274A1 (de) * 1982-03-13 1983-09-15 Bayer Ag, 5090 Leverkusen Pyridincarbonsaeureester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
PL140069B1 (en) * 1982-12-21 1987-03-31 Pfizer Method of obtaining new derivatives of dihydropiridine
IT1201454B (it) * 1985-08-19 1989-02-02 Boehringer Biochemia Srl 1,4-diidropiridine-2-sostituite

Also Published As

Publication number Publication date
IT8719700A0 (it) 1987-03-13
ATE79870T1 (de) 1992-09-15
DE3873939D1 (de) 1992-10-01
EP0282904B1 (en) 1992-08-26
JPS63243073A (ja) 1988-10-07
EP0282904A2 (en) 1988-09-21
US4918087A (en) 1990-04-17
EP0282904A3 (en) 1988-10-05

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