IT1210849B - Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che licontengono. - Google Patents

Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che licontengono.

Info

Publication number: IT1210849B
Authority: IT; Italy
Prior art keywords: erythromycin; propionic ester; salts; cooh; acid
Prior art date: 1981-02-02

Application number

IT8219410A

Other languages

English (en)

Other versions

IT8219410A0 (it

Inventor

Gonella Jacques

Original Assignee

Refarmed Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-02-02

Filing date

1982-02-02

Publication date

1989-09-29

1981-02-02 Priority claimed from FR8101930A external-priority patent/FR2502627A1/fr

1982-01-20 Priority claimed from FR8200821A external-priority patent/FR2519988B1/fr

1982-02-02 Application filed by Refarmed Sa filed Critical Refarmed Sa

1982-02-02 Publication of IT8219410A0 publication Critical patent/IT8219410A0/it

1989-09-29 Application granted granted Critical

1989-09-29 Publication of IT1210849B publication Critical patent/IT1210849B/it

Links

ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 12
229960003276 erythromycin Drugs 0.000 title abstract 6
150000003839 salts Chemical class 0.000 title abstract 2
XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical class CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 title 1
FKRCODPIKNYEAC-UHFFFAOYSA-N ethyl propionate Chemical compound CCOC(=O)CC FKRCODPIKNYEAC-UHFFFAOYSA-N 0.000 abstract 3
150000003573 thiols Chemical class 0.000 abstract 2
JJVXHDTWVIPRBZ-VKHMYHEASA-N (2r)-2-[carboxy(methyl)amino]-3-sulfanylpropanoic acid Chemical compound OC(=O)N(C)[C@@H](CS)C(O)=O JJVXHDTWVIPRBZ-VKHMYHEASA-N 0.000 abstract 1
DZLNHFMRPBPULJ-VKHMYHEASA-N L-thioproline Chemical compound OC(=O)[C@@H]1CSCN1 DZLNHFMRPBPULJ-VKHMYHEASA-N 0.000 abstract 1
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000000443 aerosol Substances 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
239000003172 expectorant agent Substances 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
231100000053 low toxicity Toxicity 0.000 abstract 1
229940066491 mucolytics Drugs 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
-1 propionyl ester Chemical class 0.000 abstract 1
NJRXVEJTAYWCQJ-UHFFFAOYSA-N thiomalic acid Chemical compound OC(=O)CC(S)C(O)=O NJRXVEJTAYWCQJ-UHFFFAOYSA-N 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)

IT8219410A 1981-02-02 1982-02-02 Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che licontengono. IT1210849B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8101930A FR2502627A1 (fr)	1981-02-02	1981-02-02	Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent
FR8200821A FR2519988B1 (fr)	1982-01-20	1982-01-20	Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent

Publications (2)

Publication Number	Publication Date
IT8219410A0 IT8219410A0 (it)	1982-02-02
IT1210849B true IT1210849B (it)	1989-09-29

Family

ID=26222205

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IT8219410A IT1210849B (it)	1981-02-02	1982-02-02	Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che licontengono.
IT8421319A IT1227789B (it)	1981-02-02	1984-06-08	Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che li contengono.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IT8421319A IT1227789B (it)	1981-02-02	1984-06-08	Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che li contengono.

Country Status (1)

Country	Link
IT (2)	IT1210849B (it)

1982
- 1982-02-02 IT IT8219410A patent/IT1210849B/it active
1984
- 1984-06-08 IT IT8421319A patent/IT1227789B/it active Protection Beyond IP Right Term

Also Published As

Publication number	Publication date
IT8421319A0 (it)	1984-06-08
IT8219410A0 (it)	1982-02-02
IT1227789B (it)	1991-05-07

Similar Documents

Publication	Publication Date	Title
GB1527871A (en)	1978-10-11	Folic acid derivatives and use in radioassay
DE3262569D1 (en)	1985-04-18	Salicylic derivatives of n-acetylcysteine
ES459659A1 (es)	1978-05-01	Procedimiento para el curtido al cromo de pellejos de anima-les.
JPS5697213A (en)	1981-08-05	Permanent wave lotion
Kaars Sijpesteijn et al.	1962	On the conversion of sodium dimethyldithiocarbamate into its α-aminobutyruc acid derivative by microorganisms
IT1104556B (it)	1985-10-21	Sale di lisina dell'acido meta-benzoil-idratropico,processo per la sua preparazione e composizione farmaceutiche che lo contengono
KR840002406A (ko)	1984-07-21	3위치가 티오메틸 복소환 그룹에 의해 치환된 신규의 세팔로스포린유도체의 제조방법세
SE7416387L (it)	1975-07-03
KR900000334A (ko)	1990-01-30	폴리아릴렌 설피드설폰의 제조방법
FR2355829A1 (fr)	1978-01-20	Nouveaux derives de la nitroxoline utile en therapeutique
JPS5231021A (en)	1977-03-09	Process for purification of crude n-omega-long-chain acyl basic amino acid or its metal salt
GB1307227A (en)	1973-02-14	Pharmaceutical compositions comprising dicarboxylic acids and their derivatives
CH609668A5 (en)	1979-03-15	Process for the preparation of acetic acid derivatives
ES8801636A1 (es)	1988-02-16	Un procedimiento para preparar nuevos derivados de imidazol
ES8207179A1 (es)	1982-09-01	Nuevo procedimiento de fabricacion de derivados de 5,6,7,7atetrahidro-4h-tieno(3,2-c)piridin-2-ona .
ES434239A1 (es)	1976-12-16	Procedimiento para la recuperacion de cefalosporina c de unmedio acuoso.
FR2310986A2 (fr)	1976-12-10	Procede de preparation d'une forme stereoisomere de carbamyl aminoacides et des aminoacides correspondants
GB1471276A (en)	1977-04-21	5-benzylpicolinic acid deri vatives
ES8800144A1 (es)	1987-11-01	Procedimiento de obtencion de un tioester de la n-acetilcisteina y de sus sales de interes terapeutico
GB1252580A (it)	1971-11-10
JPS5587783A (en)	1980-07-02	Hexahydrobenzofuranacetic acid derivative and anti-inflammatory analgesic
JPS5545624A (en)	1980-03-31	Amino acid
CH605545A5 (en)	1978-09-29	Prepn. of antiinflammatory substd. derivs. of propionic acid
JPS56142286A (en)	1981-11-06	Preparation of penicillin 1-oxide
JPS5461169A (en)	1979-05-17	Alpha-thio-alpha-(2-thienyl)caboxylic acid derivatives

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970227