IT1212041B - Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche - Google Patents

Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche

Info

Publication number
IT1212041B
IT1212041B IT8748565A IT4856587A IT1212041B IT 1212041 B IT1212041 B IT 1212041B IT 8748565 A IT8748565 A IT 8748565A IT 4856587 A IT4856587 A IT 4856587A IT 1212041 B IT1212041 B IT 1212041B
Authority
IT
Italy
Prior art keywords
gangliosides
therapeutic agents
agents capable
peripheral neuropathies
eliminating pain
Prior art date
Application number
IT8748565A
Other languages
English (en)
Other versions
IT8748565A0 (it
Inventor
Della Valle Francesco
Romeo Aurelio
Original Assignee
Fidia Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici
Priority to IT8748565A priority Critical patent/IT1212041B/it
Publication of IT8748565A0 publication Critical patent/IT8748565A0/it
Priority to US07/260,067 priority patent/US5045532A/en
Priority to AU24432/88A priority patent/AU620570B2/en
Priority to EP19880118160 priority patent/EP0315113A3/en
Priority to ZA888174A priority patent/ZA888174B/xx
Priority to DK608888A priority patent/DK608888A/da
Priority to JP63280223A priority patent/JPH01157995A/ja
Application granted granted Critical
Publication of IT1212041B publication Critical patent/IT1212041B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT8748565A 1987-11-02 1987-11-02 Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche IT1212041B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT8748565A IT1212041B (it) 1987-11-02 1987-11-02 Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
US07/260,067 US5045532A (en) 1987-11-02 1988-10-20 Inner esters of gangliosides with analgesic-antiinflammatory activity
AU24432/88A AU620570B2 (en) 1987-11-02 1988-10-28 Inner esters of gangliosides with analgesic-antiinflammatory activity
EP19880118160 EP0315113A3 (en) 1987-11-02 1988-10-31 Inner esters of gangliosides with analgesic-antiinflammatory activity
ZA888174A ZA888174B (en) 1987-11-02 1988-11-01 Inner esters of gangliosides with analgesic-antiinflammatory activity
DK608888A DK608888A (da) 1987-11-02 1988-11-01 Anvendelse af polysaccharidderivater
JP63280223A JPH01157995A (ja) 1987-11-02 1988-11-02 鎮痛−抗炎症活性を有するガングリオシドの内部エステル

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8748565A IT1212041B (it) 1987-11-02 1987-11-02 Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche

Publications (2)

Publication Number Publication Date
IT8748565A0 IT8748565A0 (it) 1987-11-02
IT1212041B true IT1212041B (it) 1989-11-08

Family

ID=11267354

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8748565A IT1212041B (it) 1987-11-02 1987-11-02 Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche

Country Status (7)

Country Link
US (1) US5045532A (it)
EP (1) EP0315113A3 (it)
JP (1) JPH01157995A (it)
AU (1) AU620570B2 (it)
DK (1) DK608888A (it)
IT (1) IT1212041B (it)
ZA (1) ZA888174B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1232175B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Analoghi semisintetici di gangliosidi
IT1232176B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Derivati di-lisogangliosidi
IT1249034B (it) * 1990-06-29 1995-02-11 Fidia Spa Impiego del monosialoganglioside gm1 e del suo derivato estere interno per impedire l'instaurarsi della tolleranza nell'uomo all'effetto analgesico della morfina e analoghi
US5646123A (en) * 1991-06-10 1997-07-08 Alberta Research Council Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen
IT1251991B (it) * 1991-11-08 1995-05-27 Fidia Spa Impiego di gangliosidi per la preparazione di composizioni farmaceutiche attive nella prevenzione di disfunzioni associate all'abuso di cocaina e psicostimolanti ad essa collegati
EP0642523B1 (en) * 1991-11-11 1997-07-16 Symbicom Ab Ganglioside analogs
JP2005527467A (ja) 2001-08-29 2005-09-15 ネオーズ テクノロジーズ， インコーポレイテッド 新規な合成ガングリオシド誘導体およびその組成物
WO2004080960A2 (en) 2003-03-06 2004-09-23 Neose Technologies Inc. Methods and compositions for the enzymatic synthesis of gangliosides
US7682794B2 (en) * 2003-07-15 2010-03-23 The Regents Of The University Of California Methods for detecting and analyzing N-glycolylneuraminic acid (Neu5Gc) in biological materials
EP2089023A2 (en) 2006-11-02 2009-08-19 Aestus Therapeutics, Inc. Methods of treating neuropathic pain with agonists of ppar-gamma
JP4005115B1 (ja) * 2007-02-08 2007-11-07 日本臓器製薬株式会社 疼痛疾患治療剤
US20120035120A1 (en) 2009-03-25 2012-02-09 Seneb Biosciences, Inc. Glycolipids as treatment for disease
WO2013151649A1 (en) 2012-04-04 2013-10-10 Sialix Inc Glycan-interacting compounds
US9879087B2 (en) 2014-11-12 2018-01-30 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
US20170306046A1 (en) 2014-11-12 2017-10-26 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
CN108463248B (zh) 2015-11-12 2022-10-21 西雅图基因公司 聚糖相互作用化合物及使用方法
EP3541847A4 (en) 2016-11-17 2020-07-08 Seattle Genetics, Inc. COMPOUNDS INTERACTING WITH GLYCANE AND METHODS OF USE
EP3589319A4 (en) 2017-03-03 2021-07-14 Seagen Inc. GLYCAN INTERACTING COMPOUNDS AND METHOD OF USE

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4593091A (en) * 1981-08-04 1986-06-03 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4476119A (en) * 1981-08-04 1984-10-09 Fidia S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4716223A (en) * 1981-08-04 1987-12-29 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
IT1168205B (it) * 1983-07-21 1987-05-20 Wellcome Italia Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione
IT1212896B (it) * 1983-11-08 1989-11-30 Della Valle Francesco Metodo di somministrazione per via inalatoria di gangliosidi e derivati, e composizioni farmaceutiche relative
IT1177863B (it) * 1984-07-03 1987-08-26 Fidia Farmaceutici Una miscela gangliosidica come agente terapeutico capare di eliminare il dolore nele neuropatie periferiche
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
IT1182209B (it) * 1985-02-18 1987-09-30 Fidia Farmaceutici Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali

Also Published As

Publication number Publication date
JPH01157995A (ja) 1989-06-21
EP0315113A2 (en) 1989-05-10
DK608888D0 (da) 1988-11-01
IT8748565A0 (it) 1987-11-02
AU620570B2 (en) 1992-02-20
DK608888A (da) 1989-05-03
EP0315113A3 (en) 1990-12-19
US5045532A (en) 1991-09-03
AU2443288A (en) 1989-05-04
ZA888174B (en) 1989-08-30

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19931201