IT1168205B - Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione - Google Patents

Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione

Info

Publication number
IT1168205B
IT1168205B IT48724/83A IT4872483A IT1168205B IT 1168205 B IT1168205 B IT 1168205B IT 48724/83 A IT48724/83 A IT 48724/83A IT 4872483 A IT4872483 A IT 4872483A IT 1168205 B IT1168205 B IT 1168205B
Authority
IT
Italy
Prior art keywords
ganglioside
sub
monsial
derivate
fungal
Prior art date
Application number
IT48724/83A
Other languages
English (en)
Other versions
IT8348724A1 (it
IT8348724A0 (it
Inventor
Ezio Tubaro
Giovanni Cavallo
Original Assignee
Wellcome Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Italia filed Critical Wellcome Italia
Publication of IT8348724A0 publication Critical patent/IT8348724A0/it
Priority to IT48724/83A priority Critical patent/IT1168205B/it
Priority to US06/632,200 priority patent/US4728641A/en
Priority to HU842819A priority patent/HU198091B/hu
Priority to AT84108621T priority patent/ATE75480T1/de
Priority to DK356984A priority patent/DK166828B1/da
Priority to JP59151160A priority patent/JPS6084296A/ja
Priority to EP84108621A priority patent/EP0136438B1/en
Priority to ES534494A priority patent/ES534494A0/es
Priority to DE8484108621T priority patent/DE3485680D1/de
Publication of IT8348724A1 publication Critical patent/IT8348724A1/it
Application granted granted Critical
Publication of IT1168205B publication Critical patent/IT1168205B/it
Priority to US07/123,763 priority patent/US4831021A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IT48724/83A 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione IT1168205B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT48724/83A IT1168205B (it) 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione
US06/632,200 US4728641A (en) 1983-07-21 1984-07-18 Ganglioside derivatives
DK356984A DK166828B1 (da) 1983-07-21 1984-07-20 Mono-sialo gangliosid gm1p, praeparater indeholdende dette samt anvendelse deraf til fremstilling af et laegemiddel
AT84108621T ATE75480T1 (de) 1983-07-21 1984-07-20 Gangliosid-derivate.
HU842819A HU198091B (en) 1983-07-21 1984-07-20 Process for producing ganglioside derivatives and pharmaceutical compositions comprising same as active ingedient
JP59151160A JPS6084296A (ja) 1983-07-21 1984-07-20 ガングリオシド誘導体
EP84108621A EP0136438B1 (en) 1983-07-21 1984-07-20 Ganglioside derivatives
ES534494A ES534494A0 (es) 1983-07-21 1984-07-20 Un procedimiento para preparar un derivado de mono-sialo-gangliosido
DE8484108621T DE3485680D1 (de) 1983-07-21 1984-07-20 Gangliosid-derivate.
US07/123,763 US4831021A (en) 1983-07-21 1987-11-23 Ganglioside derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48724/83A IT1168205B (it) 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione

Publications (3)

Publication Number Publication Date
IT8348724A0 IT8348724A0 (it) 1983-07-21
IT8348724A1 IT8348724A1 (it) 1985-01-21
IT1168205B true IT1168205B (it) 1987-05-20

Family

ID=11268264

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48724/83A IT1168205B (it) 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione

Country Status (9)

Country Link
US (2) US4728641A (it)
EP (1) EP0136438B1 (it)
JP (1) JPS6084296A (it)
AT (1) ATE75480T1 (it)
DE (1) DE3485680D1 (it)
DK (1) DK166828B1 (it)
ES (1) ES534494A0 (it)
HU (1) HU198091B (it)
IT (1) IT1168205B (it)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH660557A5 (fr) * 1984-10-26 1987-05-15 Nestle Sa Composition anti-bacterienne et procede de preparation de ses constituants actifs.
DK17885D0 (da) * 1985-01-14 1985-01-14 Karlsson Karl Anders Antiviralt middel
JPH0653764B2 (ja) * 1985-07-31 1994-07-20 三井東圧化学株式会社 モノシアロガングリオシドの製造法
ATE94395T1 (de) * 1986-05-09 1993-10-15 Pulverer Gerhard Verwendung von spezifischen monosacchariden zur herstellung eines arzneimittels zur verhinderung von metastasen maligner tumore.
IT1208751B (it) * 1986-06-30 1989-07-10 Fidia Farmaceutici Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali
EP0255717A3 (en) * 1986-08-06 1990-12-05 Mect Corporation Ganglioside related compounds and method of producing the same
IT1212041B (it) * 1987-11-02 1989-11-08 Fidia Farmaceutici Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
AU6902691A (en) * 1989-12-13 1991-07-18 Glycomed Incorporated Synthetic receptor molecules recognizable by a rotavirus
AU7153991A (en) * 1989-12-13 1991-07-18 Glycomed Incorporated Synthesis of rotavirus receptor saccharides
WO1993002686A1 (en) * 1991-07-31 1993-02-18 The Regents Of The University Of California Gangliosides with immunosuppressive ceramide moieties
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
DE4204907A1 (de) * 1992-02-14 1993-08-19 Reutter Werner Neuartige glykokonjugate mit n-substituierten neuraminsaeuren als mittel zur stimulierung des immunsystems
TW261533B (it) * 1992-07-16 1995-11-01 Kirin Brewery
KR100281264B1 (ko) * 1992-10-22 2001-02-01 마나배 게이사꾸 신규한 스핀고당 지질 및 그의 사용
JP4020958B2 (ja) * 1993-04-15 2007-12-12 キリンファーマ株式会社 新規スフィンゴ糖脂質およびその使用
DE19602108A1 (de) * 1996-01-22 1997-07-24 Beiersdorf Ag Gegen Bakterien, Parasiten, Protozoen, Mycota und Viren wirksame Substanzen
US5747476A (en) 1996-07-17 1998-05-05 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoal myeloencephalitis
DE19643585A1 (de) * 1996-10-22 1998-04-23 Beiersdorf Ag Antiadhäsive Sphingolipide
WO2002018401A2 (en) * 2000-09-01 2002-03-07 Neuronyx, Inc. Novel synthetic gangliosides
AU2001288671A1 (en) * 2000-09-01 2002-03-13 Neuronyx, Inc. Novel synthetic gangliosides
US9969980B2 (en) * 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
EP1358910A1 (de) * 2002-05-02 2003-11-05 B.R.A.H.M.S Aktiengesellschaft Verfahren und Mittel zur Prävention, Hemmung und Therapie von Krebserkrankungen
EP1367395A1 (de) * 2002-05-02 2003-12-03 B.R.A.H.M.S Aktiengesellschaft Diagnose von Neoplasmen mit Hilfe von anti-Gangliosid-Antikörpern
US9969977B2 (en) * 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
WO2004080960A2 (en) 2003-03-06 2004-09-23 Neose Technologies Inc. Methods and compositions for the enzymatic synthesis of gangliosides
JP4965063B2 (ja) * 2004-05-07 2012-07-04 雪印メグミルク株式会社 口腔内細菌叢改善剤、抗菌剤及び生育促進剤。
NZ554324A (en) 2004-09-23 2012-03-30 Csr Building Products Ltd Hybrid ventilator which can be driven either by a motor or by wind
US8354370B2 (en) * 2007-06-15 2013-01-15 Garnet Biotherapeutics, Inc. Administering a biological composition or compositions isolated from self-renewing colony forming somatic cell growth medium to treat diseases and disorders
WO2009123877A1 (en) * 2008-03-21 2009-10-08 Braincells, Inc. A method of treating a nervous system disorder by modulation of neurogenesis with mcc-257
DE102010024041A1 (de) * 2010-05-16 2013-04-04 Alfred Kroll Symtomfreiheit der Atemwege

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT295036B (de) * 1968-11-29 1971-12-27 Leikola Erkki E Verfahren zur Herstellung von neuen Produkten tierischen Ursprungs
US4125492A (en) * 1974-05-31 1978-11-14 Pedro Cuatrecasas Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers
FR2478104B1 (fr) * 1980-03-17 1986-08-08 Merieux Inst Nouveaux derives de gangliosides, leur preparation et leur application
EP0058665B1 (en) * 1980-05-09 1986-02-26 LEFFLER, Hakon Carbohydrate derivatives for inhibiting bacterial adherence
CH658458A5 (fr) * 1981-12-17 1986-11-14 Lucchini Lab Sa Procede pour l'obtention du lacto-n-norhexaosyl ceramide.

Also Published As

Publication number Publication date
EP0136438B1 (en) 1992-04-29
HUT35690A (en) 1985-07-29
ES8603191A1 (es) 1985-12-01
EP0136438A3 (en) 1987-05-13
DK356984A (da) 1985-01-22
JPS6084296A (ja) 1985-05-13
HU198091B (en) 1989-07-28
US4831021A (en) 1989-05-16
ATE75480T1 (de) 1992-05-15
ES534494A0 (es) 1985-12-01
IT8348724A1 (it) 1985-01-21
DE3485680D1 (de) 1992-06-04
EP0136438A2 (en) 1985-04-10
DK356984D0 (da) 1984-07-20
IT8348724A0 (it) 1983-07-21
US4728641A (en) 1988-03-01
DK166828B1 (da) 1993-07-19

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19930520