IT1222590B - Nuove 2-aralchil-1,4-diidropiridine,un metodo per la loro preparazione e composizioni farmaceutiche che le contengono - Google Patents

Nuove 2-aralchil-1,4-diidropiridine,un metodo per la loro preparazione e composizioni farmaceutiche che le contengono

Info

Publication number: IT1222590B
Authority: IT; Italy
Prior art keywords: alkyl; alkoxy; opt; nhcor5; substd
Prior art date: 1987-09-04

Application number

IT21796/87A

Other languages

English (en)

Other versions

IT8721796A0 (it

Inventor

Marco Frigerio

Carmelo A Gandolfi

Odoardo Tofanetti

Andrea Zaliani

Mauro Germini

Sergio Tognella

Original Assignee

Boehringer Biochemia Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-04

Filing date

1987-09-04

Publication date

1990-09-05

1987-09-04 Application filed by Boehringer Biochemia Srl filed Critical Boehringer Biochemia Srl

1987-09-04 Publication of IT8721796A0 publication Critical patent/IT8721796A0/it

1987-09-04 Priority to IT21796/87A priority Critical patent/IT1222590B/it

1987-12-21 Priority to JP88501013A priority patent/JPH02501736A/ja

1987-12-21 Priority to US07/378,515 priority patent/US5075324A/en

1987-12-21 Priority to AU11530/88A priority patent/AU1153088A/en

1987-12-21 Priority to PCT/EP1987/000815 priority patent/WO1988005043A1/en

1987-12-22 Priority to EP87119069A priority patent/EP0272693A3/en

1987-12-22 Priority to PT86440A priority patent/PT86440B/pt

1987-12-23 Priority to IE873524A priority patent/IE873524L/xx

1987-12-23 Priority to IL84932A priority patent/IL84932A0/xx

1987-12-23 Priority to CA000555178A priority patent/CA1322754C/en

1987-12-24 Priority to PH36298A priority patent/PH24933A/en

1990-09-05 Application granted granted Critical

1990-09-05 Publication of IT1222590B publication Critical patent/IT1222590B/it

Links

JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
230000003276 anti-hypertensive effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 9
125000003545 alkoxy group Chemical group 0.000 abstract 7
125000004414 alkyl thio group Chemical group 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 2
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
125000000440 benzylamino group Chemical group [H]N(*)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
125000004438 haloalkoxy group Chemical group 0.000 abstract 2
125000001188 haloalkyl group Chemical group 0.000 abstract 2
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 2
125000004953 trihalomethyl group Chemical group 0.000 abstract 2
YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical compound C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 abstract 1
125000000590 4-methylphenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)C([H])([H])[H] 0.000 abstract 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
-1 benzylthio Chemical group 0.000 abstract 1
125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 1
125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IT21796/87A 1986-12-24 1987-09-04 Nuove 2-aralchil-1,4-diidropiridine,un metodo per la loro preparazione e composizioni farmaceutiche che le contengono IT1222590B (it)

Priority Applications (11)

Application Number	Priority Date	Filing Date	Title
IT21796/87A IT1222590B (it)	1987-09-04	1987-09-04	Nuove 2-aralchil-1,4-diidropiridine,un metodo per la loro preparazione e composizioni farmaceutiche che le contengono
PCT/EP1987/000815 WO1988005043A1 (en)	1986-12-24	1987-12-21	New aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them
US07/378,515 US5075324A (en)	1986-12-24	1987-12-21	Aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical composition containing them
AU11530/88A AU1153088A (en)	1986-12-24	1987-12-21	New aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them
JP88501013A JPH02501736A (ja)	1986-12-24	1987-12-21	新規なアラルキル‐１，４‐ジヒドロピリジンおよびその製造法、ならびにそれを含有する製薬組成物
EP87119069A EP0272693A3 (en)	1986-12-24	1987-12-22	New aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them
PT86440A PT86440B (pt)	1986-12-24	1987-12-22	Processo para a preparacao de novas aralquil-1,4-di-hidropiridinas e de preparacoes farmaceuticas que as contem
IE873524A IE873524L (en)	1986-12-24	1987-12-23	New aralkyl-1, 4-dihydropyridines, a method for their¹preparation and pharmaceutical compositions containing them
IL84932A IL84932A0 (en)	1986-12-24	1987-12-23	Aralkyl-1,4-dihydropyridines,a method for their preparation and pharmaceutical compositions containing them
CA000555178A CA1322754C (en)	1986-12-24	1987-12-23	Aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them
PH36298A PH24933A (en)	1986-12-24	1987-12-24	New-aralkyl-1,4-dihydropyridines,a method for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT21796/87A IT1222590B (it)	1987-09-04	1987-09-04	Nuove 2-aralchil-1,4-diidropiridine,un metodo per la loro preparazione e composizioni farmaceutiche che le contengono

Publications (2)

Publication Number	Publication Date
IT8721796A0 IT8721796A0 (it)	1987-09-04
IT1222590B true IT1222590B (it)	1990-09-05

Family

ID=11186966

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT21796/87A IT1222590B (it)	1986-12-24	1987-09-04	Nuove 2-aralchil-1,4-diidropiridine,un metodo per la loro preparazione e composizioni farmaceutiche che le contengono

Country Status (1)

Country	Link
IT (1)	IT1222590B (it)

1987
- 1987-09-04 IT IT21796/87A patent/IT1222590B/it active

Also Published As

Publication number	Publication date
IT8721796A0 (it)	1987-09-04

Publication	Publication Date	Title
AU587623B2 (en)	1989-08-24	Herbicidal 5-imidazole carboxylic acid derivatives
ATE135911T1 (de)	1996-04-15	Verwendung von bestimmten 5-ht3- rezeptorantagonisten zur behandlung von eingeweideschmerzen
EP0129433A3 (en)	1987-05-06	Amines as fungicidal agents
HU9502841D0 (en)	1995-11-28	New imidazolidines substituted by a heterocycle, their preparation process and intermediates, their use as medicaments and the pharmaceutical compositions containing them
MX9707652A (es)	1997-11-29	Derivados de 1,3-dihidro-1-(fenilalquil)-2h-imidazol-2-ona y composiciones que los contienen usados com inhibidores de fosfodiesterasa iv y de citocina, y procedimiento para preparar dichos derivados.
HUT44523A (en)	1988-03-28	Process for producing new aromatic carboxamide derivatives and pharmaceutical compositions containing them as active components
RU97106097A (ru)	1999-05-20	Производные 2-амино-1,2,3,4-тетрагидро-нафталина, обладающие активностью в отношении сердечно-сосудистой системы
ATE45877T1 (de)	1989-09-15	Naphthalenische anti-sporiasis-wirkstoffe.
ES8602013A1 (es)	1985-11-01	Un procedimiento para preparar derivados de penem
ATE61353T1 (de)	1991-03-15	2,3-diaminoacrylonitrilderivate.
CS8609276A2 (en)	1990-12-13	Herbicide and method of its active substance preparation
ES8800201A1 (es)	1987-11-01	Procedimiento para preparar compuestos diarilicos
EP0231619A3 (en)	1988-01-27	3-phenoxy(or phenylthio)cyclopentanecarbonylamino acid analogues
ES8609254A1 (es)	1986-07-16	Un procedimiento para preparar un derivado de piridinodicar-boxilato
CS465686A2 (en)	1989-09-12	Insecticide and acaricide and method of active substances production